LLPS-Bot-2974
PRPF3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | U4/U6 small nuclear ribonucleoprotein Prp3 |
| Gene Name: | PRPF3 |
| Ensembl Gene: | ENSBTAG00000013946.4 |
| Ensembl Protein: | ENSBTAP00000066951.1 |
| Organism: | Bos taurus |
| Taxa ID: | 9913 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nuclear speckle, Nucleolus | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSBTAT00000083022.1 | ENSBTAP00000066951.1 |
| Ensembl | ENSBTAT00000080551.1 | ENSBTAP00000071368.1 |
| Ensembl | ENSBTAT00000018533.4 | ENSBTAP00000018533.3 |
| UniProt | F2Z4C4, F2Z4C4_BOVIN | |
| RefSeq | XM_005203870.3 | XP_005203927.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MALSKRELDE LKPWIEKTVK RVLGFSEPTV VTAALNCVGK GMDKKKAADH LKPFLDDSTL 60 61 RFVDKLFEAV EEGRSSRHSK SSSDRSRKRE LKEVFGDDSE ISKESSGVKK RRIPRFEEVE 120 121 EEPEVIPGPP SESPGMLTKL QIKQMMEAAT RQIEERKKQL SFISPPTPQP KTPSSSQPER 180 181 LPIGNTIQPS QAATFMNDAI EKARKAAELQ ARIQAQLALK PGLIGNANMV GLANLHAMGI 240 241 APPKVELKDQ TKPTPLILDE QGRTVDATGK EIELTHRMPT LKANIRAVKR EQFKQQLKEK 300 301 PSEDMESNTF FDPRVSIAPS QRQRRTFKFH DKGKFEKIAQ RLRTKAQLEK LQAEISQAAR 360 361 KTGIHTSTRL ALIAPKKELK EGDIPEIEWW DSYIIPNGFD LTEENPKRED YFGITNLVEH 420 421 PAQLNPPVDN DTPVTLGVYL TKKEQKKLRR QTRREAQKEL QEKVRLGLMP PPEPKVRISN 480 481 LMRVLGTEAV QDPTKVEAHV RAQMAKRQKA HEEANAARKL TAEQRKVKKI KKLKEDISQG 540 541 VHISVYRVRN LSNPAKKFKI EANAGQLYLT GVVVLHKDVN VVVVEGGPKA QKKFKRLMLH 600 601 RIKWDEQTSN TKGDDDEESD EEAVKKTNKC VLVWEGTAKD RSFGEMKFKQ CPTENMAREH 660 661 FKKHGAEHYW DLALSESVLE STD 683 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCACTAT CTAAGAGGGA GCTGGATGAA CTGAAACCAT GGATAGAAAA GACAGTGAAG 60 61 AGGGTGCTGG GTTTCTCAGA GCCCACAGTG GTCACAGCAG CACTGAACTG TGTGGGGAAG 120 121 GGCATGGACA AGAAGAAAGC AGCTGACCAT CTGAAACCTT TTCTTGATGA TTCTACTCTC 180 181 CGATTTGTGG ACAAACTGTT TGAAGCTGTG GAGGAAGGCC GAAGCTCTAG GCATTCCAAG 240 241 TCCAGCAGTG ACCGGAGCAG GAAACGAGAG CTAAAGGAAG TGTTTGGTGA TGACTCTGAG 300 301 ATCTCCAAGG AATCATCAGG AGTAAAGAAG CGACGGATAC CCCGTTTTGA AGAGGTAGAA 360 361 GAGGAGCCAG AAGTGATCCC TGGGCCTCCC TCAGAGAGTC CTGGCATGCT GACTAAGCTC 420 421 CAGATCAAAC AGATGATGGA GGCAGCAACA CGGCAAATTG AGGAGAGGAA AAAGCAACTG 480 481 AGCTTCATTA GCCCTCCTAC ACCTCAGCCA AAGACTCCTT CATCCTCCCA ACCAGAGCGA 540 541 CTTCCAATTG GCAACACTAT TCAGCCCTCC CAGGCCGCCA CTTTCATGAA TGATGCCATT 600 601 GAGAAGGCAA GGAAAGCAGC TGAACTACAA GCCCGCATCC AAGCCCAGCT GGCACTGAAG 660 661 CCAGGGCTCA TCGGCAATGC CAACATGGTG GGCCTGGCCA ATCTCCATGC TATGGGCATT 720 721 GCTCCCCCGA AGGTGGAGTT AAAAGATCAA ACTAAACCTA CACCATTGAT TCTTGATGAA 780 781 CAAGGTCGAA CTGTAGATGC AACAGGCAAG GAAATTGAGC TGACACACAG AATGCCTACT 840 841 CTGAAGGCCA ATATTCGGGC TGTGAAGAGG GAACAATTCA AGCAACAGCT AAAAGAAAAG 900 901 CCATCAGAAG ACATGGAATC TAATACCTTT TTTGATCCAC GAGTCTCAAT TGCCCCTTCC 960 961 CAGCGCCAGA GACGCACTTT TAAATTCCAT GACAAGGGCA AATTTGAAAA GATTGCCCAG 1020 1021 CGGTTACGGA CAAAGGCTCA ACTAGAGAAG CTGCAGGCAG AGATCTCACA GGCTGCTCGA 1080 1081 AAAACAGGAA TTCATACTTC AACTAGACTG GCCCTCATTG CTCCTAAGAA GGAATTGAAA 1140 1141 GAAGGCGACA TCCCTGAAAT TGAGTGGTGG GACTCTTACA TCATCCCCAA TGGCTTTGAC 1200 1201 CTTACAGAGG AAAATCCCAA GAGAGAAGAT TATTTTGGAA TCACAAATCT TGTTGAACAT 1260 1261 CCAGCCCAGC TCAACCCTCC AGTTGACAAT GACACACCAG TTACTCTGGG AGTATATCTG 1320 1321 ACCAAGAAGG AACAGAAGAA ACTTCGAAGG CAAACGAGGA GGGAAGCACA GAAGGAGCTA 1380 1381 CAGGAGAAAG TCAGGCTGGG CCTGATGCCT CCTCCAGAAC CCAAAGTGAG AATTTCAAAT 1440 1441 TTGATGCGAG TATTAGGAAC AGAAGCTGTT CAAGACCCCA CGAAGGTAGA AGCCCATGTC 1500 1501 AGAGCTCAGA TGGCAAAAAG ACAGAAAGCG CATGAAGAGG CCAATGCTGC CCGAAAACTT 1560 1561 ACAGCAGAAC AGAGAAAGGT CAAGAAAATT AAAAAGCTTA AAGAAGACAT TTCACAGGGG 1620 1621 GTACACATAT CTGTATATAG AGTTCGAAAT TTGAGCAACC CAGCCAAGAA GTTCAAGATT 1680 1681 GAGGCCAATG CTGGGCAGCT GTACCTGACA GGGGTGGTGG TACTGCACAA GGATGTCAAC 1740 1741 GTGGTAGTAG TGGAAGGGGG CCCCAAGGCC CAGAAGAAAT TTAAGCGTCT CATGCTGCAT 1800 1801 CGGATAAAGT GGGATGAACA GACATCTAAC ACAAAGGGAG ATGATGATGA GGAATCTGAT 1860 1861 GAGGAAGCTG TCAAGAAAAC CAACAAATGT GTACTAGTCT GGGAGGGTAC AGCCAAAGAC 1920 1921 CGGAGCTTTG GGGAGATGAA GTTCAAACAG TGCCCTACAG AGAACATGGC TCGGGAGCAT 1980 1981 TTCAAAAAGC ATGGGGCTGA GCACTACTGG GACCTTGCGC TGAGCGAATC TGTGCTGGAG 2040 2041 TCCACCGACT GA 2052 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Orc-3642 | Oryctolagus cuniculus | 100.0 | 0.0 | 1190 |
| LLPS-Urm-0884 | Ursus maritimus | 100.0 | 0.0 | 1190 |
| LLPS-Pat-2479 | Pan troglodytes | 100.0 | 0.0 | 1190 |
| LLPS-Hos-0444 | Homo sapiens | 100.0 | 0.0 | 1190 |
| LLPS-Fec-0410 | Felis catus | 100.0 | 0.0 | 1190 |
| LLPS-Man-2905 | Macaca nemestrina | 100.0 | 0.0 | 1190 |
| LLPS-Ict-1207 | Ictidomys tridecemlineatus | 100.0 | 0.0 | 1190 |
| LLPS-Caf-2224 | Canis familiaris | 100.0 | 0.0 | 1190 |
| LLPS-Poa-0573 | Pongo abelii | 100.0 | 0.0 | 1085 |
| LLPS-Eqc-2647 | Equus caballus | 100.0 | 0.0 | 1190 |
| LLPS-Mam-2235 | Macaca mulatta | 100.0 | 0.0 | 1063 |
| LLPS-Gog-3265 | Gorilla gorilla | 100.0 | 0.0 | 631 |
| LLPS-Caj-1913 | Callithrix jacchus | 100.0 | 0.0 | 1190 |
| LLPS-Maf-2834 | Macaca fascicularis | 100.0 | 0.0 | 1190 |
| LLPS-Aon-1177 | Aotus nancymaae | 100.0 | 0.0 | 1190 |
| LLPS-Sus-1865 | Sus scrofa | 100.0 | 0.0 | 1190 |
| LLPS-Mal-2410 | Mandrillus leucophaeus | 100.0 | 0.0 | 631 |
| LLPS-Ova-1084 | Ovis aries | 100.0 | 0.0 | 1190 |
| LLPS-Pap-0537 | Pan paniscus | 99.85 | 0.0 | 1184 |
| LLPS-Paa-0253 | Papio anubis | 99.85 | 0.0 | 1188 |
| LLPS-Aim-1604 | Ailuropoda melanoleuca | 99.85 | 0.0 | 1188 |
| LLPS-Loa-0447 | Loxodonta africana | 99.71 | 0.0 | 1189 |
| LLPS-Mea-0347 | Mesocricetus auratus | 99.71 | 0.0 | 1189 |
| LLPS-Dio-0440 | Dipodomys ordii | 99.68 | 0.0 | 1090 |
| LLPS-Cap-0976 | Cavia porcellus | 99.56 | 0.0 | 1187 |
| LLPS-Mum-2605 | Mus musculus | 99.56 | 0.0 | 1187 |
| LLPS-Cas-2902 | Carlito syrichta | 99.41 | 0.0 | 1183 |
| LLPS-Fud-0890 | Fukomys damarensis | 99.41 | 0.0 | 1184 |
| LLPS-Ran-2975 | Rattus norvegicus | 99.41 | 0.0 | 1187 |
| LLPS-Myl-0324 | Myotis lucifugus | 99.27 | 0.0 | 1182 |
| LLPS-Mod-1680 | Monodelphis domestica | 98.39 | 0.0 | 1171 |
| LLPS-Sah-3575 | Sarcophilus harrisii | 98.25 | 0.0 | 1166 |
| LLPS-Rhb-0462 | Rhinopithecus bieti | 96.45 | 3e-68 | 240 |
| LLPS-Pes-3096 | Pelodiscus sinensis | 96.05 | 0.0 | 1167 |
| LLPS-Anp-0292 | Anas platyrhynchos | 95.03 | 0.0 | 1147 |
| LLPS-Meg-0069 | Meleagris gallopavo | 94.88 | 0.0 | 1146 |
| LLPS-Gaga-0147 | Gallus gallus | 94.88 | 0.0 | 1146 |
| LLPS-Nol-0321 | Nomascus leucogenys | 94.5 | 0.0 | 982 |
| LLPS-Mup-0620 | Mustela putorius furo | 94.23 | 0.0 | 1124 |
| LLPS-Anc-1897 | Anolis carolinensis | 92.58 | 0.0 | 1112 |
| LLPS-Xet-0953 | Xenopus tropicalis | 87.5 | 0.0 | 1065 |
| LLPS-Cea-0702 | Cercocebus atys | 84.59 | 0.0 | 925 |
| LLPS-Lac-0682 | Latimeria chalumnae | 81.48 | 0.0 | 892 |
| LLPS-Tag-1682 | Taeniopygia guttata | 80.14 | 0.0 | 951 |
| LLPS-Icp-3589 | Ictalurus punctatus | 72.86 | 0.0 | 920 |
| LLPS-Asm-0904 | Astyanax mexicanus | 72.5 | 0.0 | 927 |
| LLPS-Dar-1940 | Danio rerio | 72.02 | 0.0 | 910 |
| LLPS-Orl-0042 | Oryzias latipes | 71.98 | 0.0 | 901 |
| LLPS-Scf-2884 | Scleropages formosus | 71.93 | 0.0 | 938 |
| LLPS-Xim-0009 | Xiphophorus maculatus | 71.74 | 0.0 | 901 |
| LLPS-Pof-1239 | Poecilia formosa | 71.63 | 0.0 | 895 |
| LLPS-Ten-0583 | Tetraodon nigroviridis | 71.31 | 0.0 | 911 |
| LLPS-Scm-0796 | Scophthalmus maximus | 70.79 | 0.0 | 908 |
| LLPS-Orn-0252 | Oreochromis niloticus | 70.54 | 0.0 | 901 |
| LLPS-Tar-0268 | Takifugu rubripes | 70.43 | 0.0 | 869 |
| LLPS-Gaa-0978 | Gasterosteus aculeatus | 70.07 | 0.0 | 913 |
| LLPS-Ora-1599 | Ornithorhynchus anatinus | 65.41 | 0.0 | 765 |
| LLPS-Cii-0699 | Ciona intestinalis | 59.19 | 2e-141 | 427 |
| LLPS-Cis-0840 | Ciona savignyi | 57.98 | 9e-165 | 493 |
| LLPS-Drm-1300 | Drosophila melanogaster | 53.11 | 7e-164 | 491 |
| LLPS-Cae-0997 | Caenorhabditis elegans | 47.31 | 2e-103 | 335 |
| LLPS-Scj-0203 | Schizosaccharomyces japonicus | 42.44 | 6e-69 | 241 |
| LLPS-Php-0754 | Physcomitrella patens | 40.64 | 1e-63 | 230 |
| LLPS-Asfu-0964 | Aspergillus fumigatus | 40.35 | 4e-67 | 237 |
| LLPS-Ast-0104 | Aspergillus terreus | 40.23 | 5e-42 | 162 |
| LLPS-Put-0310 | Puccinia triticina | 40.07 | 4e-40 | 158 |
| LLPS-Lep-0212 | Leersia perrieri | 40.05 | 7e-65 | 235 |
| LLPS-Asc-0860 | Aspergillus clavatus | 40.0 | 7e-69 | 242 |
| LLPS-Tra-0149 | Triticum aestivum | 40.0 | 3e-66 | 239 |
| LLPS-Abg-1444 | Absidia glauca | 40.0 | 6e-74 | 255 |
| LLPS-Scp-0722 | Schizosaccharomyces pombe | 39.95 | 1e-66 | 235 |
| LLPS-Hov-1993 | Hordeum vulgare | 39.91 | 1e-62 | 229 |
| LLPS-Sei-1136 | Setaria italica | 39.64 | 5e-65 | 236 |
| LLPS-Nef-0909 | Neosartorya fischeri | 39.6 | 3e-66 | 234 |
| LLPS-Sob-1119 | Sorghum bicolor | 39.59 | 2e-65 | 237 |
| LLPS-Scc-0812 | Schizosaccharomyces cryophilus | 39.15 | 7e-72 | 248 |
| LLPS-Arl-1677 | Arabidopsis lyrata | 39.11 | 9e-66 | 237 |
| LLPS-Gor-0263 | Gossypium raimondii | 38.99 | 3e-70 | 249 |
| LLPS-Tum-0476 | Tuber melanosporum | 38.9 | 3e-68 | 240 |
| LLPS-Zyt-0331 | Zymoseptoria tritici | 38.86 | 1e-62 | 225 |
| LLPS-Zem-0432 | Zea mays | 38.69 | 4e-64 | 233 |
| LLPS-Blg-0775 | Blumeria graminis | 38.64 | 2e-64 | 228 |
| LLPS-Orbr-1295 | Oryza brachyantha | 38.62 | 2e-64 | 233 |
| LLPS-Asni-1144 | Aspergillus niger | 38.61 | 2e-65 | 231 |
| LLPS-Thc-0703 | Theobroma cacao | 38.49 | 3e-67 | 241 |
| LLPS-Mae-0183 | Manihot esculenta | 38.48 | 1e-66 | 241 |
| LLPS-Ors-1094 | Oryza sativa | 38.46 | 3e-63 | 224 |
| LLPS-Sol-1125 | Solanum lycopersicum | 38.46 | 6e-70 | 247 |
| LLPS-Orgl-1472 | Oryza glumaepatula | 38.46 | 2e-59 | 219 |
| LLPS-Ved-0806 | Verticillium dahliae | 38.4 | 7e-69 | 238 |
| LLPS-Beb-0735 | Beauveria bassiana | 38.38 | 3e-61 | 218 |
| LLPS-Brd-0213 | Brachypodium distachyon | 38.33 | 3e-65 | 235 |
| LLPS-Fuo-0304 | Fusarium oxysporum | 38.3 | 1e-66 | 233 |
| LLPS-Chr-0462 | Chlamydomonas reinhardtii | 38.26 | 1e-37 | 154 |
| LLPS-Org-0372 | Oryza glaberrima | 38.25 | 5e-61 | 221 |
| LLPS-Orm-0122 | Oryza meridionalis | 38.25 | 1e-58 | 217 |
| LLPS-Orb-0656 | Oryza barthii | 38.25 | 5e-61 | 221 |
| LLPS-Sot-1600 | Solanum tuberosum | 38.2 | 2e-67 | 243 |
| LLPS-Mao-1415 | Magnaporthe oryzae | 38.18 | 1e-62 | 222 |
| LLPS-Amt-1381 | Amborella trichopoda | 38.14 | 8e-69 | 246 |
| LLPS-Gas-0468 | Galdieria sulphuraria | 38.1 | 5e-67 | 237 |
| LLPS-Fuv-0328 | Fusarium verticillioides | 38.05 | 3e-65 | 229 |
| LLPS-Coc-0756 | Corchorus capsularis | 38.04 | 5e-65 | 234 |
| LLPS-Cogr-0577 | Colletotrichum graminicola | 37.98 | 2e-68 | 237 |
| LLPS-Scs-0223 | Sclerotinia sclerotiorum | 37.94 | 3e-67 | 235 |
| LLPS-Tru-0494 | Triticum urartu | 37.84 | 2e-54 | 199 |
| LLPS-Nia-0980 | Nicotiana attenuata | 37.75 | 4e-67 | 241 |
| LLPS-Orr-1600 | Oryza rufipogon | 37.72 | 7e-61 | 223 |
| LLPS-Asn-0894 | Aspergillus nidulans | 37.72 | 3e-63 | 227 |
| LLPS-Prp-0931 | Prunus persica | 37.68 | 7e-65 | 236 |
| LLPS-Pot-0686 | Populus trichocarpa | 37.58 | 5e-69 | 247 |
| LLPS-Trv-0208 | Trichoderma virens | 37.56 | 3e-63 | 223 |
| LLPS-Orni-1079 | Oryza nivara | 37.52 | 2e-59 | 219 |
| LLPS-Ori-1665 | Oryza indica | 37.52 | 2e-59 | 219 |
| LLPS-Orp-0592 | Oryza punctata | 37.35 | 5e-61 | 223 |
| LLPS-Asf-1132 | Aspergillus flavus | 37.35 | 7e-64 | 228 |
| LLPS-Aso-1004 | Aspergillus oryzae | 37.35 | 2e-64 | 228 |
| LLPS-Nec-1023 | Neurospora crassa | 37.33 | 3e-55 | 201 |
| LLPS-Hea-1318 | Helianthus annuus | 37.27 | 2e-68 | 244 |
| LLPS-Lem-0242 | Leptosphaeria maculans | 37.24 | 3e-61 | 222 |
| LLPS-Fus-0467 | Fusarium solani | 37.22 | 5e-63 | 222 |
| LLPS-Cus-1130 | Cucumis sativus | 37.18 | 7e-63 | 230 |
| LLPS-Trr-0184 | Trichoderma reesei | 37.04 | 4e-62 | 220 |
| LLPS-Bro-1223 | Brassica oleracea | 37.0 | 2e-65 | 236 |
| LLPS-Brn-0770 | Brassica napus | 37.0 | 4e-66 | 237 |
| LLPS-Crn-1000 | Cryptococcus neoformans | 36.94 | 3e-56 | 204 |
| LLPS-Yal-0479 | Yarrowia lipolytica | 36.84 | 1e-50 | 189 |
| LLPS-Mel-0210 | Melampsora laricipopulina | 36.79 | 4e-65 | 232 |
| LLPS-Art-0634 | Arabidopsis thaliana | 36.77 | 8e-67 | 240 |
| LLPS-Dos-0336 | Dothistroma septosporum | 36.48 | 5e-58 | 213 |
| LLPS-Spr-0664 | Sporisorium reilianum | 36.36 | 1e-56 | 209 |
| LLPS-Met-1382 | Medicago truncatula | 36.28 | 9e-64 | 232 |
| LLPS-Map-0214 | Magnaporthe poae | 36.19 | 3e-66 | 232 |
| LLPS-Chc-0101 | Chondrus crispus | 36.18 | 2e-59 | 216 |
| LLPS-Viv-0707 | Vitis vinifera | 36.12 | 4e-66 | 239 |
| LLPS-Usm-0165 | Ustilago maydis | 35.97 | 3e-53 | 199 |
| LLPS-Vir-0787 | Vigna radiata | 35.97 | 9e-66 | 238 |
| LLPS-Cog-1035 | Colletotrichum gloeosporioides | 35.9 | 3e-59 | 213 |
| LLPS-Glm-0131 | Glycine max | 35.85 | 2e-66 | 239 |
| LLPS-Brr-0396 | Brassica rapa | 35.7 | 5e-60 | 220 |
| LLPS-Pyt-1280 | Pyrenophora teres | 35.61 | 3e-60 | 216 |
| LLPS-Phv-0559 | Phaseolus vulgaris | 35.51 | 1e-66 | 240 |
| LLPS-Pytr-0972 | Pyrenophora triticirepentis | 35.43 | 1e-60 | 217 |
| LLPS-Via-0011 | Vigna angularis | 35.38 | 9e-64 | 232 |
| LLPS-Phn-0578 | Phaeosphaeria nodorum | 35.35 | 6e-60 | 215 |
| LLPS-Gag-0680 | Gaeumannomyces graminis | 35.32 | 3e-64 | 227 |
| LLPS-Osl-0101 | Ostreococcus lucimarinus | 34.92 | 6e-53 | 194 |
| LLPS-Miv-0188 | Microbotryum violaceum | 34.85 | 3e-57 | 211 |
| LLPS-Mua-1645 | Musa acuminata | 34.81 | 5e-51 | 194 |
| LLPS-Sem-1180 | Selaginella moellendorffii | 34.61 | 6e-56 | 208 |
| LLPS-Pug-0713 | Puccinia graminis | 33.71 | 1e-62 | 225 |
| LLPS-Kop-0081 | Komagataella pastoris | 33.1 | 8e-51 | 188 |
| LLPS-Coo-0649 | Colletotrichum orbiculare | 32.66 | 1e-63 | 225 |
| LLPS-Asg-0724 | Ashbya gossypii | 29.37 | 5e-24 | 109 |
| LLPS-Sac-1362 | Saccharomyces cerevisiae | 27.3 | 2e-20 | 99.0 |