• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Aso-1470
fbaA

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Fructose-bisphosphate aldolase
Gene Name: fbaA, AO090003000725
Ensembl Gene: AO090003000725
Ensembl Protein: BAE57870
Organism: Aspergillus oryzae
Taxa ID: 510516
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION


Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MGVGVLEKLS  RKTGVIVGDD  VLRLFEHAQQ  NNYAIPAVNV  TSSSTVVASL  EAARDQNCPI  60
61    VLQLSQGGAA  YFAGKGVSND  GQQASIAGGI  AAAHYIRSLA  PAYGIPVVLH  TDHCAKKLLP  120
121   WLDGLLDEDE  RYFKLHGEPL  FSSHMIDLSE  EPVDYNIQTT  AAYLKRAAPM  KQWLEMEIGI  180
181   TGGEEDGVNN  EDVDNNSLYT  QPEDILAIHK  ALSPISPYFS  IAAGFGNVHG  VYKPGNVKLH  240
241   PELLKKHQAY  VKEKIGSNKD  KPVFFVFHGG  SGSSKEEYKE  AISYGVVKVN  VDTDMQFAYM  300
301   SGIRDYILKK  KDYLMTAVGN  PEGEDKPNKK  SFDPRVWVRE  GEKTMSQRVK  VALEDFNTAG  360
361   QL  362

▼ KEYWORD


ID
Family
Complete proteome
Glycolysis
Lyase
Metal-binding
Reference proteome
Zinc

▼ GENE ONTOLOGY


ID
Classification
Description
Molecular Function
Fructose-bisphosphate aldolase activity
Molecular Function
Zinc ion binding
Biological Process
Glycolytic process

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asf-1492Aspergillus flavus100.00.0 645
LLPS-Ast-0308Aspergillus terreus91.670.0 592
LLPS-Asni-0220Aspergillus niger90.560.0 592
LLPS-Nef-1216Neosartorya fischeri90.560.0 593
LLPS-Asc-1393Aspergillus clavatus90.00.0 585
LLPS-Asfu-1516Aspergillus fumigatus90.00.0 592
LLPS-Asn-0812Aspergillus nidulans88.610.0 582
LLPS-Beb-0788Beauveria bassiana82.780.0 536
LLPS-Fuv-1196Fusarium verticillioides82.50.0 530
LLPS-Trv-1033Trichoderma virens82.50.0 532
LLPS-Trr-1373Trichoderma reesei82.50.0 530
LLPS-Fuo-1243Fusarium oxysporum82.220.0 528
LLPS-Blg-1295Blumeria graminis80.280.0 517
LLPS-Fus-1541Fusarium solani80.280.0 524
LLPS-Dos-1249Dothistroma septosporum78.254e-174 496
LLPS-Zyt-0796Zymoseptoria tritici77.971e-172 492
LLPS-Phn-1089Phaeosphaeria nodorum77.782e-174 497
LLPS-Pyt-1177Pyrenophora teres77.187e-172 491
LLPS-Gag-1289Gaeumannomyces graminis76.676e-175 498
LLPS-Tum-0222Tuber melanosporum76.125e-173 496
LLPS-Coo-0685Colletotrichum orbiculare75.562e-165 474
LLPS-Map-1315Magnaporthe poae75.02e-171 489
LLPS-Cog-1374Colletotrichum gloeosporioides74.651e-161 464
LLPS-Mao-0107Magnaporthe oryzae74.175e-168 481
LLPS-Cogr-1112Colletotrichum graminicola74.023e-165 474
LLPS-Lem-1221Leptosphaeria maculans73.525e-157 452
LLPS-Ved-0822Verticillium dahliae73.338e-1473.6
LLPS-Nec-0063Neurospora crassa73.29e-168 480
LLPS-Kop-0349Komagataella pastoris71.995e-160 461
LLPS-Yal-0695Yarrowia lipolytica70.722e-158 456
LLPS-Pytr-1572Pyrenophora triticirepentis70.635e-155 448
LLPS-Crn-1372Cryptococcus neoformans70.354e-150 435
LLPS-Scj-0389Schizosaccharomyces japonicus68.894e-150 435
LLPS-Scp-1125Schizosaccharomyces pombe68.868e-151 437
LLPS-Asg-1005Ashbya gossypii68.332e-155 449
LLPS-Scc-0477Schizosaccharomyces cryophilus67.515e-149 432
LLPS-Sac-0473Saccharomyces cerevisiae66.391e-148 431
LLPS-Spr-1355Sporisorium reilianum66.392e-149 433
LLPS-Usm-0316Ustilago maydis66.393e-148 430
LLPS-Mel-0036Melampsora laricipopulina64.573e-137 402
LLPS-Put-1144Puccinia triticina63.041e-133 395
LLPS-Abg-1805Absidia glauca62.227e-132 389
LLPS-Pug-0033Puccinia graminis62.127e-134 394
LLPS-Miv-0268Microbotryum violaceum59.432e-125 374
LLPS-Osl-0530Ostreococcus lucimarinus53.352e-110 333
LLPS-Via-2056Vigna angularis40.481e-0757.8
LLPS-Vir-1703Vigna radiata40.484e-0756.2
LLPS-Thc-0413Theobroma cacao39.534e-0756.2
LLPS-Art-2596Arabidopsis thaliana39.295e-0755.8
LLPS-Glm-1878Glycine max28.376e-0755.5