LLPS-Aso-1450
hacA
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Transcriptional activator hacA |
| Gene Name: | hacA, AO090124000074 |
| Ensembl Gene: | AO090124000074 |
| Ensembl Protein: | BAE62622 |
| Organism: | Aspergillus oryzae |
| Taxa ID: | 510516 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| Transcriptional activator involved in the unfolded protein response (UPR) pathway. Recognizes and binds to the UPR element (UPRE) in the promoter of UPR-regulated genes. Increases the synthesis of endoplasmic reticulum-resident proteins required for protein folding as well as components of the secretory pathway (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | BAE62622 | BAE62622 |
| UniProt | Q1XGE2, HAC1_ASPOR, Q2U743 | |
| GeneBank | AP007165, AB246349 | BAE93063.1, BAE62622.1 |
| RefSeq | XM_001823703.2 | XP_001823755.2 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSCDMEKTMS SVDSLPATPA SEVPVLTVSP ADTSLNSADV KTQEVKPEEK KPAKKRKSWG 60 61 QELPVPKTNL PPRKRAKTED EKEQRRIERV LRNRAAAQTS RERKRLEMEK LENEKIQMEQ 120 121 QNQFLLQRLS QMEAENNRLS QQLAQLAAEV RGSRANTPMP GSPATASPTL TPTLFKQERD 180 181 ELPLERIPFP TPSLSDYSPT LKPSTLAESS DVAQHPAAVL LSVAGLEGDG SALPLFDLGS 240 241 DLKHHSTDDV AAPLSDDDFN RLFHGDSSVE PDSSVFEDGL AFDVLEGGDL SAFPFDSMVN 300 301 FDSEPVTLEG IEMAHGLPDE TTCKTSSVQP GFGASTTRCD GQGIAAGC 348 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Biological Process | Response to unfolded protein |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Asf-1459 | Aspergillus flavus | 100.0 | 3e-112 | 341 |
| LLPS-Nef-1553 | Neosartorya fischeri | 87.68 | 2e-86 | 274 |
| LLPS-Asfu-0351 | Aspergillus fumigatus | 86.73 | 9e-84 | 267 |
| LLPS-Asc-0787 | Aspergillus clavatus | 86.73 | 3e-87 | 276 |
| LLPS-Asn-0214 | Aspergillus nidulans | 83.65 | 2e-78 | 253 |
| LLPS-Asni-1342 | Aspergillus niger | 79.94 | 9e-162 | 463 |
| LLPS-Ast-0385 | Aspergillus terreus | 76.16 | 1e-145 | 422 |
| LLPS-Fuv-1575 | Fusarium verticillioides | 65.17 | 2e-18 | 90.5 |
| LLPS-Fuo-1312 | Fusarium oxysporum | 62.92 | 7e-18 | 88.6 |
| LLPS-Blg-1472 | Blumeria graminis | 48.85 | 1e-23 | 104 |