• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asn-0667
kex1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pheromone-processing carboxypeptidase kex1; Carboxypeptidase D
Gene Name: kex1, AN1384
Ensembl Gene: ANIA_10184
Ensembl Protein: CBF87602
Organism: Aspergillus nidulans
Taxa ID: 227321
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity).

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGLLSFRQPS  WRISRSQFYP  IWALSQLLLN  PIAVLAQSAA  DYYVESLPGA  PEGPLLKMHA  60
61    GHIEVDPEHN  GHLFFWHYQN  RHIANRQRTI  IWLNGGPGCS  SMDGALMEIG  PYRLKDNETL  120
121   EYNEGSWDEF  ANLLFVDQPV  GTGFSFANTN  SYLHELDEMA  AQFITFLEKW  FAVFPEYERD  180
181   DIYIAGESYA  GQYIPYIAKA  IQDRNKDIHE  KQSSSARWNL  RGLLIGNGWI  SPAEQYPAYL  240
241   SFAYEEGLVE  EGSKLGKELE  TLLSICKSKM  ETGPKISITD  CEAVLNKLLD  KTVDSNNQCI  300
301   NMYDIRLRDG  SCGTTWPPDL  VDVKPYLHTY  EVIQALNISP  EKESGWDECD  GNVGAAFRPQ  360
361   KSEPSVKLLP  GLLESGIEIL  LFSGDKDLIC  NHVGTEQLIS  NMKWAGGTGF  ETSPGVWAPR  420
421   HDWTFEDEPA  GYYQYARNLT  YVLLYNASHM  APFDLPRRTR  DMVDRFMHVD  IASIGGAPAD  480
481   SRIDGEPLPQ  TSVGGQPNST  VHQEEEQQKI  KETEWNAYAK  SGEAVLVVVI  IGVLVWGFLI  540
541   WRSRRRHNGY  SGIAIKSPSR  TSIMGRFHNN  HSNGADVEAG  DFDEAELDDL  HSPGLDRENY  600
601   AVGEDSDDEA  HRQDLPRAQE  SSSKSENNLV  T  631
Nucleotide CDS Sequence (FASTA)
1     ATGGGTCTTT  TGTCATTCCG  CCAACCCTCT  TGGAGGATAA  GCCGCTCACA  ATTCTATCCA  60
61    ATATGGGCAT  TGTCACAACT  CCTCCTTAAT  CCCATCGCAG  TTTTAGCTCA  GTCTGCAGCC  120
121   GACTATTATG  TGGAATCTTT  ACCCGGGGCC  CCAGAGGGCC  CGTTACTAAA  GATGCATGCT  180
181   GGACATATTG  AGGTAGACCC  GGAGCACAAC  GGACATCTTT  TTTTCTGGCA  CTATCAAAAT  240
241   CGGCACATTG  CAAATCGCCA  GCGAACAATA  ATCTGGTTGA  ATGGGGGACC  CGGCTGCAGC  300
301   TCCATGGATG  GCGCGCTGAT  GGAGATTGGC  CCGTACCGTC  TGAAAGATAA  CGAAACTCTA  360
361   GAATATAACG  AGGGATCATG  GGACGAGTTC  GCAAATCTTC  TCTTTGTTGA  TCAGCCTGTT  420
421   GGAACCGGTT  TCAGCTTCGC  CAATACCAAT  AGCTATCTGC  ATGAGCTAGA  TGAAATGGCT  480
481   GCCCAATTCA  TCACTTTCTT  GGAGAAATGG  TTCGCCGTGT  TTCCCGAGTA  CGAGCGAGAT  540
541   GATATCTACA  TCGCTGGCGA  ATCATATGCG  GGCCAATATA  TTCCATACAT  TGCAAAAGCT  600
601   ATTCAGGATC  GAAACAAAGA  CATCCACGAA  AAGCAATCTA  GCAGTGCGCG  TTGGAATCTT  660
661   CGCGGTCTTC  TTATTGGCAA  TGGTTGGATA  TCGCCGGCGG  AACAATATCC  GGCGTATTTG  720
721   AGCTTTGCCT  ATGAAGAAGG  TCTTGTTGAG  GAAGGTAGCA  AGCTTGGAAA  AGAGCTTGAA  780
781   ACTTTACTCT  CTATCTGCAA  GTCTAAGATG  GAAACTGGAC  CTAAAATATC  CATAACGGAC  840
841   TGTGAAGCTG  TTTTGAATAA  GCTTCTGGAC  AAGACTGTGG  ATTCGAACAA  CCAATGCATC  900
901   AATATGTACG  ATATTCGGCT  CAGGGACGGT  TCTTGTGGTA  CGACCTGGCC  ACCAGACTTG  960
961   GTGGATGTGA  AGCCATATTT  ACATACCTAT  GAGGTGATTC  AAGCATTGAA  TATCAGCCCA  1020
1021  GAGAAAGAGT  CAGGCTGGGA  CGAATGTGAC  GGCAATGTGG  GGGCCGCATT  TCGGCCGCAA  1080
1081  AAATCCGAAC  CATCAGTCAA  ATTGCTCCCC  GGCTTGCTCG  AGTCGGGTAT  CGAAATCCTC  1140
1141  CTCTTCAGCG  GCGATAAAGA  TCTAATTTGC  AATCACGTCG  GGACTGAGCA  ACTTATTAGC  1200
1201  AACATGAAGT  GGGCAGGTGG  TACTGGCTTT  GAAACATCCC  CGGGGGTATG  GGCTCCACGA  1260
1261  CACGACTGGA  CGTTCGAAGA  TGAGCCGGCC  GGTTACTATC  AGTATGCGAG  GAACTTGACT  1320
1321  TACGTTCTCC  TTTACAATGC  CAGTCACATG  GCCCCCTTCG  ATCTTCCCCG  CCGCACGCGA  1380
1381  GACATGGTGG  ACCGCTTCAT  GCACGTTGAT  ATCGCCAGCA  TCGGCGGTGC  ACCTGCGGAT  1440
1441  TCACGCATCG  ATGGCGAACC  GTTGCCTCAA  ACTTCTGTGG  GCGGTCAGCC  CAACAGCACA  1500
1501  GTTCACCAAG  AGGAAGAGCA  GCAAAAGATT  AAAGAAACCG  AGTGGAACGC  CTACGCAAAG  1560
1561  TCCGGTGAAG  CCGTCCTTGT  CGTTGTTATT  ATCGGTGTGC  TGGTCTGGGG  TTTTCTCATC  1620
1621  TGGCGCAGTC  GCCGGCGACA  CAATGGCTAC  AGCGGAATTG  CCATTAAATC  CCCAAGTAGA  1680
1681  ACCTCTATCA  TGGGCCGTTT  CCATAACAAT  CATAGTAACG  GCGCAGACGT  AGAGGCCGGT  1740
1741  GACTTTGATG  AGGCTGAGTT  GGATGACTTA  CACTCGCCAG  GCCTGGACCG  GGAAAATTAT  1800
1801  GCTGTCGGGG  AAGACAGTGA  TGACGAAGCG  CATCGACAGG  ATCTACCACG  CGCCCAAGAA  1860
1861  TCTTCATCGA  AAAGCGAGAA  TAATCTTGTA  ACGTAA  1896

▼ KEYWORD

ID
Family
Apoptosis
Carboxypeptidase
Complete proteome
Glycoprotein
Golgi apparatus
Hydrolase
Membrane
Protease
Reference proteome
Signal
Transmembrane
Transmembrane helix

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of membrane
Cellular Component
Trans-Golgi network
Molecular Function
Serine-type carboxypeptidase activity
Biological Process
Apoptotic process
Biological Process
Proteolysis involved in cellular protein catabolic process

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aso-1347Aspergillus oryzae74.490.0 888
LLPS-Asfu-0319Aspergillus fumigatus74.490.0 903
LLPS-Asf-0989Aspergillus flavus74.190.0 833
LLPS-Asc-1351Aspergillus clavatus72.940.0 898
LLPS-Nef-1575Neosartorya fischeri72.60.0 900
LLPS-Map-0995Magnaporthe poae61.760.0 711
LLPS-Gag-1604Gaeumannomyces graminis60.580.0 699
LLPS-Mao-1035Magnaporthe oryzae60.030.0 703
LLPS-Pyt-0608Pyrenophora teres59.750.0 691
LLPS-Fus-0740Fusarium solani58.460.0 679
LLPS-Zyt-1197Zymoseptoria tritici57.740.0 605
LLPS-Cog-0776Colletotrichum gloeosporioides57.310.0 682
LLPS-Phn-1248Phaeosphaeria nodorum56.820.0 697
LLPS-Beb-0221Beauveria bassiana56.380.0 659
LLPS-Pytr-1128Pyrenophora triticirepentis56.380.0 686
LLPS-Tum-1357Tuber melanosporum56.330.0 649
LLPS-Trv-1159Trichoderma virens56.160.0 670
LLPS-Trr-1632Trichoderma reesei55.640.0 684
LLPS-Lem-1106Leptosphaeria maculans55.160.0 702
LLPS-Abg-1087Absidia glauca44.023e-125 390
LLPS-Viv-1531Vitis vinifera33.092e-50 186
LLPS-Brr-2666Brassica rapa32.464e-21 102
LLPS-Vir-1729Vigna radiata32.32e-45 178
LLPS-Via-0752Vigna angularis32.045e-45 171
LLPS-Sob-1930Sorghum bicolor31.892e-44 169
LLPS-Glm-2822Glycine max31.622e-47 177
LLPS-Sol-2402Solanum lycopersicum31.355e-45 171
LLPS-Pot-1191Populus trichocarpa31.18e-49 182
LLPS-Coc-1075Corchorus capsularis31.09e-46 173
LLPS-Sot-2030Solanum tuberosum30.881e-43 167
LLPS-Cus-2379Cucumis sativus30.865e-57 206
LLPS-Chs-0243Chlorocebus sabaeus30.811e-52 193
LLPS-Maf-4706Macaca fascicularis30.811e-51 190
LLPS-Mal-1824Mandrillus leucophaeus30.813e-51 189
LLPS-Paa-0547Papio anubis30.812e-51 190
LLPS-Man-3144Macaca nemestrina30.812e-51 190
LLPS-Mam-1548Macaca mulatta30.812e-51 190
LLPS-Sei-2237Setaria italica30.772e-43 166
LLPS-Zem-0297Zea mays30.775e-45 171
LLPS-Mua-0192Musa acuminata30.653e-61 218
LLPS-Gor-0537Gossypium raimondii30.648e-41 159
LLPS-Bro-2177Brassica oleracea30.627e-43 165
LLPS-Prp-0656Prunus persica30.621e-42 164
LLPS-Cea-4586Cercocebus atys30.578e-51 188
LLPS-Rhb-4585Rhinopithecus bieti30.574e-51 189
LLPS-Hos-1379Homo sapiens30.561e-52 193
LLPS-Brd-1068Brachypodium distachyon30.461e-56 205
LLPS-Met-2070Medicago truncatula30.439e-47 176
LLPS-Phv-2104Phaseolus vulgaris30.433e-42 162
LLPS-Hov-2099Hordeum vulgare30.412e-43 166
LLPS-Mup-2091Mustela putorius furo30.417e-49 182
LLPS-Brn-0467Brassica napus30.399e-41 158
LLPS-Coo-1393Colletotrichum orbiculare30.382e-44 174
LLPS-Pap-0062Pan paniscus30.324e-53 194
LLPS-Pat-1020Pan troglodytes30.323e-53 195
LLPS-Tra-3056Triticum aestivum30.313e-42 163
LLPS-Aim-4219Ailuropoda melanoleuca30.282e-42 164
LLPS-Mae-2318Manihot esculenta30.242e-43 166
LLPS-Eqc-3281Equus caballus30.247e-47 178
LLPS-Hea-2716Helianthus annuus30.23e-45 172
LLPS-Orp-1431Oryza punctata30.189e-45 170
LLPS-Gog-2737Gorilla gorilla30.097e-52 191
LLPS-Urm-4002Ursus maritimus29.924e-42 162
LLPS-Loa-1439Loxodonta africana29.95e-43 165
LLPS-Lep-0632Leersia perrieri29.842e-56 204
LLPS-Thc-1741Theobroma cacao29.683e-45 173
LLPS-Art-2781Arabidopsis thaliana29.633e-40 157
LLPS-Poa-1675Pongo abelii29.627e-50 186
LLPS-Orbr-1829Oryza brachyantha29.573e-56 204
LLPS-Orni-1221Oryza nivara29.535e-57 206
LLPS-Orb-0958Oryza barthii29.536e-57 206
LLPS-Orm-1498Oryza meridionalis29.535e-57 206
LLPS-Orc-1811Oryctolagus cuniculus29.523e-50 187
LLPS-Ors-2289Oryza sativa29.491e-41 161
LLPS-Org-1951Oryza glaberrima29.491e-41 161
LLPS-Amt-1112Amborella trichopoda29.462e-43 166
LLPS-Orr-2310Oryza rufipogon29.42e-40 158
LLPS-Ict-2111Ictidomys tridecemlineatus29.365e-48 180
LLPS-Arl-2054Arabidopsis lyrata29.292e-38 151
LLPS-Dac-0776Daucus carota29.274e-43 166
LLPS-Mea-0792Mesocricetus auratus29.264e-46 175
LLPS-Ori-0808Oryza indica29.266e-41 159
LLPS-Orgl-0812Oryza glumaepatula29.262e-40 157
LLPS-Cap-1090Cavia porcellus29.214e-44 169
LLPS-Otg-0672Otolemur garnettii29.012e-40 157
LLPS-Fud-1894Fukomys damarensis28.981e-44 171
LLPS-Anc-1970Anolis carolinensis28.975e-45 173
LLPS-Osl-0041Ostreococcus lucimarinus28.912e-49 185
LLPS-Ora-1812Ornithorhynchus anatinus28.95e-46 174
LLPS-Ran-2969Rattus norvegicus28.85e-49 183
LLPS-Aon-2612Aotus nancymaae28.745e-51 189
LLPS-Mum-3381Mus musculus28.676e-49 183
LLPS-Tru-1638Triticum urartu28.675e-53 195
LLPS-Caf-1321Canis familiaris28.572e-46 176
LLPS-Fec-4537Felis catus28.541e-47 179
LLPS-Myl-1012Myotis lucifugus28.513e-48 181
LLPS-Nia-1066Nicotiana attenuata28.513e-44 169
LLPS-Tar-3131Takifugu rubripes28.473e-51 189
LLPS-Nol-4390Nomascus leucogenys28.271e-45 172
LLPS-Lac-2802Latimeria chalumnae28.245e-47 177
LLPS-Bot-0682Bos taurus28.235e-43 167
LLPS-Dar-2112Danio rerio28.015e-46 174
LLPS-Ova-0264Ovis aries27.992e-43 167
LLPS-Orn-3929Oreochromis niloticus27.923e-48 181
LLPS-Scm-3656Scophthalmus maximus27.753e-49 184
LLPS-Pes-3062Pelodiscus sinensis27.743e-45 172
LLPS-Xim-3515Xiphophorus maculatus27.656e-48 181
LLPS-Caj-4388Callithrix jacchus27.584e-45 172
LLPS-Sah-2176Sarcophilus harrisii27.584e-39 154
LLPS-Xet-3955Xenopus tropicalis27.553e-45 172
LLPS-Ten-2773Tetraodon nigroviridis27.44e-46 175
LLPS-Mod-3542Monodelphis domestica27.366e-40 156
LLPS-Gaa-0821Gasterosteus aculeatus27.299e-48 179
LLPS-Sem-2270Selaginella moellendorffii27.111e-30 129
LLPS-Scf-3195Scleropages formosus27.066e-45 171
LLPS-Pof-0369Poecilia formosa27.03e-44 169
LLPS-Icp-3333Ictalurus punctatus26.982e-42 164
LLPS-Sus-3951Sus scrofa26.95e-41 159
LLPS-Php-0898Physcomitrella patens26.541e-35 143
LLPS-Cas-2676Carlito syrichta26.31e-1685.1
LLPS-Leo-2740Lepisosteus oculatus26.219e-43 165
LLPS-Dio-3524Dipodomys ordii25.872e-39 154
LLPS-Drm-2259Drosophila melanogaster25.543e-34 140
LLPS-Orl-3603Oryzias latipes25.056e-39 154
LLPS-Chr-1596Chlamydomonas reinhardtii24.071e-29 126