DrLLPS - Data resource of LLPS

LLPS-Asm-a389

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Mitochondrial Rho GTPase
Ensembl Gene:	ENSAMXG00000034712.1
Ensembl Protein:	ENSAMXP00000049773.1
Organism:	Astyanax mexicanus
Taxa ID:	7994
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Postsynaptic density	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-a457	Q8IXI2	Client	Postsynaptic density	73.49	0.0	1040
Mus musculus	LLPS-Mum-a454	Q8BG51	Client	Postsynaptic density	72.75	0.0	1036

▼ FUNCTION

Mitochondrial GTPase involved in mitochondrial trafficking.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSAMXT00000042242.1	ENSAMXP00000049773.1
Ensembl	ENSAMXT00000042844.1	ENSAMXP00000046199.1
Ensembl	ENSAMXT00000010589.2	ENSAMXP00000010589.2
Ensembl	ENSAMXT00000055056.1	ENSAMXP00000037309.1
Ensembl	ENSAMXT00000030621.1	ENSAMXP00000053474.1
Ensembl	ENSAMXT00000046917.1	ENSAMXP00000039641.1
UniProt		W5KSM7, W5KSM7_ASTMX

▼ SEQUENCE

Protein Sequence (FASTA)
1 MLFPVLCSIE AEQSDEQLYQ EISKANVICI VYSVNNKKSI EKVTSHWIPL INDRTDKDSR 60 61 VPLILVGNKS DLVEHSSMET ILPIMNQYSE IETCVECSAK NLKNISELFY YAQKAVLHPT 120 121 GPLYCPEEKE MKPSCIKALT RIFKISDLDN DGVLNDNELN FFQRTCFNMP LAPQALEDVK 180 181 NVVRRNMTDG VKDNGLTLKG FLFLHTLFIQ RGRHETTWTV LRRFGYDDDL ELTQEYLFPL 240 241 LKIPPDCTTE LNHNAYLFLQ SVFDKHDKDR DCALSPDELK DLFKVFPYMP WGPDVNNTVC 300 301 TNEQGWITYQ GYLSQWTLTT YLDVQRCLEY LGYLGYSIIH EQESQAAAIT VTRNKRIDLQ 360 361 KKQTQRSVFR CNVLGAQGSG KSGFLQAFLG RNVTRQKKIR DDHKSYYAIS TTYVYGQEKY 420 421 LLLHEVLPVF EVLSEADLAC DVVCLVYDIS NPRSFEYCAK AYKKYFMDSK TPCMMIAAKS 480 481 DLHEVRQHYS LSPLDFCRRH KLHPPQQFSC NSADAPSKDI YTKLTTMAMY PHVKFRCMCS 540 541 CNRCTFCICQ NLLNCELLRT VRAKFCSAVL NRLGPWVDEV GAYLLADEET SLIHQVHEVT 600 601 FVEDSIYMES SVDPFVPRHM TQTDLKNSTF WLRASVGATV FAVLGFAMYK ALLKQR 656

Protein Sequence (FASTA)

1     MLFPVLCSIE  AEQSDEQLYQ  EISKANVICI  VYSVNNKKSI  EKVTSHWIPL  INDRTDKDSR  60
61    VPLILVGNKS  DLVEHSSMET  ILPIMNQYSE  IETCVECSAK  NLKNISELFY  YAQKAVLHPT  120
121   GPLYCPEEKE  MKPSCIKALT  RIFKISDLDN  DGVLNDNELN  FFQRTCFNMP  LAPQALEDVK  180
181   NVVRRNMTDG  VKDNGLTLKG  FLFLHTLFIQ  RGRHETTWTV  LRRFGYDDDL  ELTQEYLFPL  240
241   LKIPPDCTTE  LNHNAYLFLQ  SVFDKHDKDR  DCALSPDELK  DLFKVFPYMP  WGPDVNNTVC  300
301   TNEQGWITYQ  GYLSQWTLTT  YLDVQRCLEY  LGYLGYSIIH  EQESQAAAIT  VTRNKRIDLQ  360
361   KKQTQRSVFR  CNVLGAQGSG  KSGFLQAFLG  RNVTRQKKIR  DDHKSYYAIS  TTYVYGQEKY  420
421   LLLHEVLPVF  EVLSEADLAC  DVVCLVYDIS  NPRSFEYCAK  AYKKYFMDSK  TPCMMIAAKS  480
481   DLHEVRQHYS  LSPLDFCRRH  KLHPPQQFSC  NSADAPSKDI  YTKLTTMAMY  PHVKFRCMCS  540
541   CNRCTFCICQ  NLLNCELLRT  VRAKFCSAVL  NRLGPWVDEV  GAYLLADEET  SLIHQVHEVT  600
601   FVEDSIYMES  SVDPFVPRHM  TQTDLKNSTF  WLRASVGATV  FAVLGFAMYK  ALLKQR  656

▼ KEYWORD

ID	Family
KW-0106	Calcium
KW-0181	Complete proteome
KW-0342	GTP-binding
KW-0378	Hydrolase
KW-0472	Membrane
KW-0496	Mitochondrion
KW-1000	Mitochondrion outer membrane
KW-0547	Nucleotide-binding
KW-1185	Reference proteome
KW-0812	Transmembrane
KW-1133	Transmembrane helix

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0031307	Cellular Component	Integral component of mitochondrial outer membrane
GO:0005509	Molecular Function	Calcium ion binding
GO:0005525	Molecular Function	GTP binding
GO:0003924	Molecular Function	GTPase activity
GO:0007005	Biological Process	Mitochondrion organization

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Hos-a457	Homo sapiens	0.0	1040	undefined
LLPS-Mum-a454	Mus musculus	0.0	1036	undefined

LLPS-Asm-a389

Protein Sequence

Nucleotide Sequence