LLPS-Asm-a234
AK1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Adenylate kinase isoenzyme 1 |
| Gene Name: | AK1 |
| Ensembl Gene: | ENSAMXG00000040942.1 |
| Ensembl Protein: | ENSAMXP00000028085.1 |
| Organism: | Astyanax mexicanus |
| Taxa ID: | 7994 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSAMXT00000032503.1 | ENSAMXP00000028085.1 |
| Ensembl | ENSAMXT00000040006.1 | ENSAMXP00000042473.1 |
| Ensembl | ENSAMXT00000046338.1 | ENSAMXP00000038915.1 |
| UniProt | A0A3B1JAM3, A0A3B1JAM3_ASTMX |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MGQGCFSALW RRSTHPADPQ PDKIKDAKII FVVGGPGSGK GTQCEKVVAK YGYTHLSSGD 60 61 LLRAEVASGS ERGKQLQAIM QKGELVPLDT VLDMIKDAMI AKADVSKGFL IDGYPREVKQ 120 121 GEEFEKKIGA PALLLYVDAK SETMVKRLMK RGETSGRADD NEETIKKRLD LYYKATEPVI 180 181 TFYEGRGIVR KINSELAVDD VFAEVSKAID GLK 213 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | Adenylate kinase activity | |
Molecular Function | ATP binding | |
Molecular Function | Nucleoside diphosphate kinase activity | |
Biological Process | ADP biosynthetic process | |
Biological Process | AMP metabolic process | |
Biological Process | ATP metabolic process | |
Biological Process | Nucleoside triphosphate biosynthetic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a274 | Homo sapiens | 5e-103 | 305 | undefined |
| LLPS-Mum-a273 | Mus musculus | 3e-106 | 313 | undefined |