• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asm-2401

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Coatomer subunit beta'
Ensembl Gene: ENSAMXG00000005818.2
Ensembl Protein: ENSAMXP00000006074.2
Organism: Astyanax mexicanus
Taxa ID: 7994
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPLRLDIKRK  LTARSDRVKS  VDLHPTEPWM  LASLYNGSVC  VWNHETQTLV  KTFEVCDLPV  60
61    RASKFVARKN  WVITGADDMQ  IRVFNYNTLE  RVHMFEAHSD  YIRCIAVHPT  QPYILTSSDD  120
121   MLIKLWDWEK  KWSCSQVFEG  HTHYVMQIVI  NPKDNNQFAS  ASLDRTIKVW  QLGSSSPNFT  180
181   LEGHEKGVNC  IDYYSGGDKP  YLISGADDRL  VKIWDYQNKT  CVQTLEGHAQ  NVSCVSFHPE  240
241   LPIIVTGSED  GTVRIWHSST  YRLESTLNYG  MERVWCVCGL  RGSNNVALGY  DEGSIIIKLG  300
301   REEPAMSMDT  NGKIIWAKHS  EVQQANLKAM  GDAEIKDGER  LPLAVKDMGS  CEIYPQTIQH  360
361   NPNGRFVVVC  GDGEYIIYTA  MALRNKSFGS  AQEFVWAHDS  SEYAIRESNS  LVKIFKNFKE  420
421   KKSFRPDFGA  EGIYGGFLLG  VRSVNGLAFY  DWENTELIRR  IEIQPKHIFW  SDSGELVCIA  480
481   TEESFFILRY  LADKVAASQE  SNEGVTEDGI  EDAFEVQGEI  QEIVKTGLWV  GDCFIYTSSV  540
541   NRLNYFVGGE  IVTIAHLDRT  MYLLGYIPKD  DRLYLGDKEL  NIVSYSLLVS  VLEYQTAVMR  600
601   RDFGMADKVL  PTIPKEQRTR  VAHFLEKQGF  KQQALAVSTD  PEHRFELALQ  LGELKIAYQL  660
661   AVEAESEQKW  KQLAELAISK  CQFGLAQECL  HHAQDYGGLL  LLATASGNAA  MVSKLAEGAE  720
721   RDGKNNVAFM  TYFLQGKLDQ  CLELLIRTNR  LPEAAFLART  YLPSQVSRVV  KLWRESLSKV  780
781   NQKAAESLAD  PTEYENLFPG  LKEAFVAEHF  LRETCLGKTR  PATDYPLVTP  NEERNVLEEA  840
841   SGYEPKGVLP  TPPQQVDDSE  EAPAEAGVLA  SVMAAVSAPV  ASAVASFAPP  EPEPVKEPEV  900
901   DIEVGDELKD  KTLEELEDDL  DNMELDDIDT  TDVNLDDDFL  DD  942
Nucleotide CDS Sequence (FASTA)
1     ATGCCTCTGA  GGCTGGACAT  CAAGCGCAAG  CTCACGGCTC  GGTCCGACCG  TGTCAAGAGC  60
61    GTGGACCTTC  ATCCCACGGA  GCCATGGATG  CTGGCCAGTC  TGTACAACGG  CAGCGTCTGC  120
121   GTCTGGAACC  ATGAAACACA  AACCTTGGTG  AAGACGTTTG  AAGTGTGCGA  CCTGCCAGTA  180
181   CGAGCCTCAA  AGTTTGTGGC  CAGGAAAAAC  TGGGTTATCA  CTGGAGCAGA  TGATATGCAG  240
241   ATTCGGGTTT  TCAACTACAA  CACACTAGAA  CGGGTCCATA  TGTTCGAGGC  TCATTCGGAT  300
301   TATATCCGCT  GCATTGCTGT  GCACCCCACC  CAGCCCTACA  TCCTTACTAG  TAGTGATGAC  360
361   ATGCTGATTA  AGCTGTGGGA  CTGGGAGAAG  AAGTGGTCCT  GTAGCCAGGT  GTTTGAGGGC  420
421   CACACACACT  ACGTCATGCA  GATCGTCATC  AACCCCAAAG  ACAACAACCA  GTTTGCTAGT  480
481   GCATCGCTGG  ACAGAACCAT  CAAGGTCTGG  CAGCTGGGAT  CCTCGTCTCC  TAACTTCACT  540
541   CTGGAGGGTC  ATGAGAAAGG  AGTGAACTGC  ATTGATTATT  ACAGTGGAGG  AGATAAGCCT  600
601   TATCTTATTT  CTGGAGCTGA  TGACAGGCTG  GTGAAGATTT  GGGACTACCA  GAATAAGACG  660
661   TGTGTGCAGA  CTCTTGAAGG  TCATGCTCAG  AATGTATCAT  GTGTGAGCTT  CCACCCAGAG  720
721   CTGCCCATCA  TCGTCACAGG  ATCTGAGGAT  GGCACAGTAC  GTATCTGGCA  CTCCAGCACT  780
781   TATCGACTGG  AGAGCACACT  GAACTACGGC  ATGGAGCGGG  TGTGGTGTGT  CTGTGGCCTG  840
841   CGTGGCTCCA  ACAATGTGGC  GTTAGGTTAT  GATGAGGGCA  GCATCATTAT  CAAGCTTGGT  900
901   CGTGAAGAGC  CAGCCATGTC  AATGGATACC  AATGGAAAGA  TTATCTGGGC  TAAGCACTCT  960
961   GAGGTTCAGC  AGGCTAACCT  AAAGGCAATG  GGGGATGCTG  AGATTAAAGA  TGGAGAGAGG  1020
1021  CTGCCTCTGG  CTGTAAAAGA  CATGGGCAGC  TGCGAGATCT  ACCCACAGAC  TATTCAACAC  1080
1081  AACCCTAATG  GAAGGTTTGT  GGTGGTGTGT  GGAGATGGGG  AGTACATCAT  CTACACAGCA  1140
1141  ATGGCTCTGA  GGAACAAAAG  CTTCGGCTCA  GCTCAGGAGT  TTGTCTGGGA  GCAATATGTT  1200
1201  GTCCAATCAC  ATTACAAATA  CCAGTCTCTC  TCTCTTTTTC  ATTTATTTAT  CTTTTGTTTA  1260
1261  GGTATCTATG  GTGGATTTTT  GCTGGGCGTC  AGGTCTGTTA  ACGGTTTGGC  CTTCTATGAC  1320
1321  TGGGAGAACA  CAGAGCTGAT  TCGACGCATT  GAGATTCAAC  CCAAACATAT  CTTCTGGTCA  1380
1381  GACTCTGGAG  AGCTGGTGTG  TATCGCCACT  GAGGAGTCCT  TCTTCATCCT  GCGCTATCTG  1440
1441  GCTGATAAAG  TGGCTGCATC  TCAAGAGTCT  AATGAGGGAG  TGACTGAAGA  TGGTATTGAA  1500
1501  GATGCTTTTG  AGTGCACTTA  TAAATACATT  CAAAGTGAGA  TCCAGGAGAT  TGTAAAGACA  1560
1561  GGTCTGTGGG  TGGGAGACTG  CTTCATCTAC  ACAAGCTCTG  TCAACAGGCT  CAACTACTTT  1620
1621  GTAGGAGGAG  AGATTGTCAC  CATCGCCCAC  CTGGACAGGA  CTATGTACCT  GCTGGGCTAC  1680
1681  ATCCCTAAAG  ATGACCGACT  GTACCTGGGA  GACAAGGAGC  TGAACATTGT  TAGTTACTCT  1740
1741  CTACTGGTGT  CGGTTCTGGA  GTACCAGACG  GCGGTAATGC  GGCGAGACTT  TGGAATGGCC  1800
1801  GATAAAGTAC  TTCCCACCAT  TCCAAAAGAG  CAGAGGACCA  GAGTGGCCCA  TTTTCTGGAG  1860
1861  AAACAGGGCT  TCAAGCAGCA  GGCACTTGCT  GTATCCACTG  ACCCAGAGCA  CAGATTTGAG  1920
1921  CTTGCTCTGC  AATTAGGAGA  ACTGAAGATC  GCCTACCAAT  TAGCAGTAGA  AGCAGAGTCT  1980
1981  GAGCAGAAGT  GGAAGCAGTT  GGCTGAGCTG  GCCATCAGCA  AGTGCCAGTT  TGGGCTGGCC  2040
2041  CAGGAGTGCC  TCCATCATGC  CCAGGACTAT  GGTGGCTTGC  TGCTGCTGGC  CACCGCCTCC  2100
2101  GGTAACGCTG  CTATGGTGAG  CAAACTGGCC  GAAGGTGCCG  AGCGCGATGG  CAAGAACAAC  2160
2161  GTGGCCTTTA  TGACCTACTT  CCTGCAGGGG  AAATTGGACC  AGTGTCTGGA  ACTCCTGATC  2220
2221  AGGACCAATC  GGTTGCCTGA  GGCTGCCTTT  TTGGCTCGCA  CGTATCTACC  CAGCCAAGTG  2280
2281  TCCAGAGTGG  TGAAGCTGTG  GAGAGAGAGC  CTGTCTAAAG  TAAACCAAAA  GGCAGCCGAG  2340
2341  TCTCTGGCCG  ACCCCACGGA  GTACGAGAAC  CTGTTCCCTG  GCCTGAAGGA  GGCTTTTGTG  2400
2401  GCCGAGCACT  TTCTCCGTGA  GACCTGCCTG  GGCAAGACTA  GACCGGCTAC  TGACTACCCA  2460
2461  CTGGTCACGG  TGAGACACTG  TTTGTTTATA  CACTTATACA  CCTCTTTTAC  TACTCTGGAG  2520
2521  GAACTGGAAG  ACGACTTGGA  CAACATGGAG  CTGGATGACA  TCGACACCAC  AGACGTCAAC  2580
2581  CTGGACGACG  ACTTCTTAGA  CGATTAA  2607

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Cytoplasmic vesicle
ER-Golgi transport
Golgi apparatus
Membrane
Protein transport
Reference proteome
Transport
WD repeat

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPI-coated vesicle membrane
Cellular Component
Golgi membrane
Cellular Component
Membrane coat
Molecular Function
Structural molecule activity
Biological Process
Intracellular protein transport
Biological Process
Vesicle-mediated transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Icp-0929Ictalurus punctatus97.00.01763
LLPS-Orn-3226Oreochromis niloticus96.270.01739
LLPS-Leo-1193Lepisosteus oculatus96.110.01719
LLPS-Scm-3814Scophthalmus maximus96.00.01719
LLPS-Dar-1571Danio rerio95.720.01741
LLPS-Gaa-0096Gasterosteus aculeatus95.560.01723
LLPS-Dio-0888Dipodomys ordii95.540.01061
LLPS-Xim-1685Xiphophorus maculatus95.270.01741
LLPS-Orl-1413Oryzias latipes95.170.01742
LLPS-Pof-1757Poecilia formosa95.040.01738
LLPS-Scf-0669Scleropages formosus94.90.01715
LLPS-Ten-0313Tetraodon nigroviridis94.80.01717
LLPS-Lac-0678Latimeria chalumnae94.580.01698
LLPS-Pes-0327Pelodiscus sinensis94.460.01691
LLPS-Chs-0761Chlorocebus sabaeus94.360.01145
LLPS-Tar-3113Takifugu rubripes94.250.01720
LLPS-Gaga-1309Gallus gallus94.240.01697
LLPS-Anp-0002Anas platyrhynchos94.240.01695
LLPS-Caf-2611Canis familiaris94.080.01676
LLPS-Bot-1193Bos taurus94.080.01675
LLPS-Ova-1538Ovis aries94.080.01677
LLPS-Anc-1773Anolis carolinensis93.970.01680
LLPS-Aim-2042Ailuropoda melanoleuca93.960.01672
LLPS-Mup-2166Mustela putorius furo93.960.01674
LLPS-Sus-2822Sus scrofa93.960.01675
LLPS-Ora-1131Ornithorhynchus anatinus93.90.01626
LLPS-Tut-0499Tursiops truncatus93.850.01670
LLPS-Gog-4667Gorilla gorilla93.720.01667
LLPS-Mea-3748Mesocricetus auratus93.490.01571
LLPS-Fud-0412Fukomys damarensis92.980.01558
LLPS-Mod-1623Monodelphis domestica92.640.01691
LLPS-Eqc-3186Equus caballus92.580.01674
LLPS-Xet-2061Xenopus tropicalis92.540.01655
LLPS-Mam-1003Macaca mulatta92.470.01675
LLPS-Cas-1284Carlito syrichta92.470.01675
LLPS-Fec-3371Felis catus92.470.01675
LLPS-Urm-0131Ursus maritimus92.470.01678
LLPS-Man-0479Macaca nemestrina92.470.01675
LLPS-Paa-2734Papio anubis92.470.01676
LLPS-Maf-0629Macaca fascicularis92.470.01675
LLPS-Aon-0657Aotus nancymaae92.470.01675
LLPS-Cea-1602Cercocebus atys92.470.01675
LLPS-Caj-1943Callithrix jacchus92.470.01677
LLPS-Sah-0061Sarcophilus harrisii92.410.01690
LLPS-Cap-4053Cavia porcellus92.350.01675
LLPS-Pat-0965Pan troglodytes92.350.01673
LLPS-Mal-4496Mandrillus leucophaeus92.350.01672
LLPS-Pap-4121Pan paniscus92.340.01670
LLPS-Nol-1561Nomascus leucogenys92.30.01662
LLPS-Loa-2950Loxodonta africana92.250.01666
LLPS-Ict-1521Ictidomys tridecemlineatus92.170.01676
LLPS-Mum-3057Mus musculus92.170.01676
LLPS-Hos-0103Homo sapiens92.120.01670
LLPS-Tag-2537Taeniopygia guttata91.910.01693
LLPS-Myl-0406Myotis lucifugus91.890.01640
LLPS-Fia-1494Ficedula albicollis91.760.01639
LLPS-Orc-0950Oryctolagus cuniculus91.120.01669
LLPS-Poa-0082Pongo abelii89.980.01582
LLPS-Ran-1798Rattus norvegicus81.280.01226
LLPS-Cii-0200Ciona intestinalis78.320.01437
LLPS-Cis-0411Ciona savignyi76.390.01433
LLPS-Rhb-4052Rhinopithecus bieti76.040.01298
LLPS-Drm-1052Drosophila melanogaster70.820.01296
LLPS-Hov-2206Hordeum vulgare66.841e-91 295
LLPS-Sei-2320Setaria italica64.120.01103
LLPS-Cae-1807Caenorhabditis elegans63.50.01197
LLPS-Zem-0748Zea mays63.460.01112
LLPS-Viv-0873Vitis vinifera63.070.01113
LLPS-Met-1542Medicago truncatula63.00.01128
LLPS-Glm-2305Glycine max62.880.01120
LLPS-Orbr-1352Oryza brachyantha62.840.01100
LLPS-Brd-1243Brachypodium distachyon62.720.01105
LLPS-Sob-2284Sorghum bicolor62.640.01120
LLPS-Org-0006Oryza glaberrima62.470.01105
LLPS-Ors-2280Oryza sativa62.470.01108
LLPS-Php-1866Physcomitrella patens62.450.01099
LLPS-Prp-1297Prunus persica62.390.01113
LLPS-Gor-0353Gossypium raimondii62.380.01108
LLPS-Abg-0427Absidia glauca62.360.01092
LLPS-Pot-0169Populus trichocarpa62.350.01111
LLPS-Sem-0072Selaginella moellendorffii62.350.01080
LLPS-Mae-0415Manihot esculenta62.270.01115
LLPS-Phv-1580Phaseolus vulgaris62.270.01109
LLPS-Thc-0237Theobroma cacao62.150.01112
LLPS-Nia-2644Nicotiana attenuata62.140.01122
LLPS-Via-0965Vigna angularis62.130.01090
LLPS-Art-2394Arabidopsis thaliana62.030.01106
LLPS-Bro-2686Brassica oleracea61.960.01112
LLPS-Arl-1738Arabidopsis lyrata61.960.01110
LLPS-Brr-0123Brassica rapa61.910.01111
LLPS-Brn-2105Brassica napus61.910.01109
LLPS-Hea-2432Helianthus annuus61.910.01105
LLPS-Coc-1959Corchorus capsularis61.360.01030
LLPS-Cus-0945Cucumis sativus61.360.01107
LLPS-Dac-1730Daucus carota61.360.01085
LLPS-Orr-0815Oryza rufipogon61.230.01077
LLPS-Orgl-0376Oryza glumaepatula61.230.01076
LLPS-Orb-0714Oryza barthii61.230.01076
LLPS-Orni-1245Oryza nivara61.230.01077
LLPS-Sot-0221Solanum tuberosum61.010.01029
LLPS-Phn-1220Phaeosphaeria nodorum60.784e-129 411
LLPS-Sol-1528Solanum lycopersicum60.740.01118
LLPS-Amt-0760Amborella trichopoda60.210.01070
LLPS-Osl-1339Ostreococcus lucimarinus60.070.01051
LLPS-Chr-1449Chlamydomonas reinhardtii59.930.01035
LLPS-Lep-1077Leersia perrieri59.580.01090
LLPS-Vir-1710Vigna radiata59.380.01007
LLPS-Ori-1775Oryza indica59.050.01078
LLPS-Mua-0314Musa acuminata58.930.01102
LLPS-Tra-1041Triticum aestivum58.90.01098
LLPS-Orp-1855Oryza punctata57.540.01063
LLPS-Orm-1924Oryza meridionalis56.60.0 998
LLPS-Asc-1567Aspergillus clavatus56.510.0 974
LLPS-Fuo-1131Fusarium oxysporum56.260.0 952
LLPS-Tum-1463Tuber melanosporum56.130.0 982
LLPS-Asn-1557Aspergillus nidulans55.950.0 961
LLPS-Fus-1391Fusarium solani55.930.0 959
LLPS-Fuv-0027Fusarium verticillioides55.830.0 951
LLPS-Mao-0790Magnaporthe oryzae55.690.0 952
LLPS-Ved-0349Verticillium dahliae55.360.0 959
LLPS-Cogr-0142Colletotrichum graminicola55.360.0 963
LLPS-Map-0121Magnaporthe poae55.330.0 955
LLPS-Dos-1366Dothistroma septosporum55.190.0 973
LLPS-Zyt-1366Zymoseptoria tritici55.190.0 977
LLPS-Trr-0261Trichoderma reesei55.090.0 959
LLPS-Gag-0040Gaeumannomyces graminis55.090.0 952
LLPS-Coo-0328Colletotrichum orbiculare55.090.0 961
LLPS-Pyt-0091Pyrenophora teres55.020.0 972
LLPS-Chc-0314Chondrus crispus54.860.0 990
LLPS-Ast-0694Aspergillus terreus54.690.0 960
LLPS-Pytr-1221Pyrenophora triticirepentis54.590.0 923
LLPS-Trv-0735Trichoderma virens54.590.0 954
LLPS-Beb-0391Beauveria bassiana54.240.0 927
LLPS-Lem-0914Leptosphaeria maculans54.220.0 942
LLPS-Pug-0156Puccinia graminis54.170.0 937
LLPS-Put-0633Puccinia triticina54.050.0 933
LLPS-Blg-0294Blumeria graminis53.910.0 955
LLPS-Asfu-0899Aspergillus fumigatus53.50.0 973
LLPS-Nec-0778Neurospora crassa53.480.0 935
LLPS-Aso-0195Aspergillus oryzae53.460.0 967
LLPS-Mel-1012Melampsora laricipopulina53.460.0 922
LLPS-Nef-1473Neosartorya fischeri53.220.0 962
LLPS-Gas-0964Galdieria sulphuraria53.00.0 960
LLPS-Asf-1094Aspergillus flavus52.990.0 914
LLPS-Spr-1212Sporisorium reilianum52.380.0 940
LLPS-Miv-0438Microbotryum violaceum52.180.0 928
LLPS-Tru-1025Triticum urartu52.030.0 938
LLPS-Crn-1297Cryptococcus neoformans51.330.0 912
LLPS-Usm-1435Ustilago maydis51.160.0 918
LLPS-Yal-0704Yarrowia lipolytica50.80.0 873
LLPS-Kop-0741Komagataella pastoris49.690.0 867
LLPS-Cym-0140Cyanidioschyzon merolae48.530.0 843
LLPS-Scj-1378Schizosaccharomyces japonicus47.720.0 832
LLPS-Sac-0164Saccharomyces cerevisiae47.430.0 783
LLPS-Cog-0449Colletotrichum gloeosporioides46.770.0 751
LLPS-Scp-0593Schizosaccharomyces pombe46.650.0 825
LLPS-Asg-0867Ashbya gossypii46.40.0 751
LLPS-Scc-1234Schizosaccharomyces cryophilus45.320.0 798
LLPS-Asni-1486Aspergillus niger24.569e-81 290