LLPS-Asfu-a032
AFUA_4G07710
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pyruvate carboxylase |
| Gene Name: | AFUA_4G07710 |
| Ensembl Gene: | AFUA_4G07710 |
| Ensembl Protein: | EAL90016 |
| Organism: | Aspergillus fumigatus |
| Taxa ID: | 330879 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EAL90016 | EAL90016 |
| UniProt | Q4WP18, Q4WP18_ASPFU | |
| GeneBank | AAHF01000005 | EAL90016.1 |
| RefSeq | XM_746961.1 | XP_752054.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAAFRQPEE AVDDTHFIDD HHEHHRDSVH RRLRANSAIM QFQKILVANR GEIPIRIFRT 60 61 AHELSLQTVA IYSYEDRLSM HRQKADEAYM IGHRGQYTPV AAYLAIDEIV KIAQEHGVHL 120 121 IHPGYGFLSE NAEFARKVEN AGIVFVGPTP ETIEALGDKV SARQLAIKCG VPVVPGTPGP 180 181 VERYEEVKAF TDTYGFPIII KAAFGGGGRG MRVVRDQADL RDAFERATSE ARSAFGNGTV 240 241 FVERFLDRPK HIEVQLLGDN HGNVIHLFER DCSVQRRHQK VVEIAPAKDL PNDVRDRILA 300 301 DAVKLAKTVN YRNAGTAEFL VDQQNRYYFI EINPRIQVEH TITEEITGID IVAAQIQIAA 360 361 GATLEQLGLT QDRISTRGFA IQCRITTEDP ANGFRPDTGK IEVYRSAGGN GVRLDGGNGF 420 421 AGAIISPHYD SMLVKCTCRG STYEIARRKV VRALVEFRIR GVKTNIPFLT SLLSHPTFID 480 481 GTCWTTFIDD TPELFALIGS QNRAQKLLAY LGDVAVNGSS IKGQIGEPKL KGEIIKPTLL 540 541 DDAGKPIDVS VPCAQGWKQI IDREGPAAFA KAVRANKGCL IMDTTWRDAH QSLLATRVRT 600 601 IDLLNIAKET SHAYANAYSL ECWGGATFDV AMRFLYEDPW DRLRKLRKAV PNIPFQMLLR 660 661 GANGVAYSSL PDNAIYHFCK QAKKCGVDIF RVFDALNDVD QLEVGIKAVQ AAEGVVEATI 720 721 CYSGDMLNPK KKYNLEYYLA LVDKIVKLNP HILGIKDMAG VLKPQAARLL VGSIRERYPD 780 781 LPIHVHTHDS AGTGVASMVA CAQAGADAVD AATDSMSGMT SQPSVGAILA SLEGTEHDPK 840 841 LNLAHVRAID SYWQQLRLLY SPFEAGLTGP DPEVYEHEIP GGQLTNLLFQ ASQLGLGQQW 900 901 AETKKAYESA NDLLGDIVKV TPTSKVVGDL AQFMVSNKLT PEDVVARAGE LDFPGSVLEF 960 961 LEGLMGQPFG GFPEPLRSKA LRGRRKLDKR PGLYLEPLDL AKIKNQIREK YGSATEYDVA 1020 1021 SYAMYPKVFE DYKKFVQKFG DLSILPTRYF LAKPEIGEEF HVELEQGKVL ILKLLAIGPL 1080 1081 SEQTGQREVF YEVNGEVRQV TVDDNKASVD NTARPKADIG DSSQIGAPMS GVVVEIRVHE 1140 1141 GSEVKKGDPV AVLSAMKMEM VISAPHSGKV SGLLVKEGDS VDGQDLICKI AKA 1193 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCTG CCTTTCGCCA GCCCGAGGAG GCGGTCGATG ACACCCACTT CATCGATGAT 60 61 CATCATGAGC ACCACAGAGA CTCGGTCCAC CGCCGGCTAC GTGCCAACTC TGCCATCATG 120 121 CAATTTCAAA AGATCCTTGT CGCCAACCGT GGTGAAATTC CCATCCGTAT CTTCCGTACC 180 181 GCCCACGAAC TTTCTCTCCA GACAGTCGCC ATCTACTCGT ATGAGGATCG TCTGTCCATG 240 241 CACCGCCAGA AGGCCGACGA GGCCTACATG ATCGGTCATC GCGGTCAATA TACCCCCGTT 300 301 GCGGCCTACT TGGCCATTGA TGAGATCGTC AAGATTGCTC AGGAGCATGG TGTGCACCTG 360 361 ATTCACCCCG GTTACGGCTT CTTGTCTGAG AACGCCGAGT TTGCTCGCAA GGTCGAGAAT 420 421 GCTGGTATTG TCTTTGTGGG CCCCACCCCG GAGACCATCG AAGCCCTCGG CGACAAGGTC 480 481 TCTGCCCGTC AATTGGCCAT CAAGTGCGGC GTCCCCGTGG TCCCCGGTAC TCCTGGTCCA 540 541 GTGGAGCGCT ACGAGGAGGT CAAGGCCTTC ACCGACACCT ATGGCTTCCC CATCATCATC 600 601 AAGGCTGCCT TCGGCGGTGG TGGCCGTGGT ATGCGTGTCG TCCGCGATCA GGCCGATCTG 660 661 CGGGACGCCT TTGAGCGTGC TACCTCCGAG GCCCGCTCTG CGTTTGGTAA CGGCACCGTC 720 721 TTCGTCGAGC GTTTCCTCGA CCGCCCCAAG CACATCGAAG TCCAGCTTCT CGGTGACAAC 780 781 CACGGTAACG TCATCCACCT GTTCGAGCGT GACTGCTCCG TTCAGCGCCG TCACCAGAAG 840 841 GTCGTTGAGA TCGCCCCCGC CAAGGATCTG CCGAACGATG TGCGCGACCG CATTTTGGCG 900 901 GATGCGGTGA AGCTGGCCAA GACGGTCAAC TACCGCAACG CCGGTACCGC CGAGTTCCTG 960 961 GTTGACCAGC AGAACCGCTA CTACTTCATC GAAATCAACC CTCGTATTCA GGTCGAGCAC 1020 1021 ACCATCACCG AGGAAATCAC CGGCATCGAT ATTGTCGCTG CTCAGATCCA AATCGCTGCC 1080 1081 GGTGCCACGC TGGAGCAGTT GGGCCTGACC CAGGACCGCA TCTCCACCCG CGGTTTCGCC 1140 1141 ATCCAGTGCC GTATCACCAC CGAAGACCCG GCTAACGGCT TCAGACCCGA TACTGGAAAG 1200 1201 ATCGAAGTCT ACCGTTCCGC TGGTGGAAAC GGCGTTCGTT TGGACGGTGG CAACGGTTTC 1260 1261 GCGGGTGCCA TCATCTCCCC TCACTACGAC TCCATGCTGG TCAAGTGTAC CTGCCGTGGT 1320 1321 TCCACATACG AGATTGCGCG CCGCAAGGTC GTGCGTGCCC TGGTCGAATT CCGTATTCGC 1380 1381 GGTGTCAAGA CCAACATTCC GTTCCTCACC TCACTGCTGA GCCACCCCAC CTTCATTGAT 1440 1441 GGCACGTGCT GGACCACCTT CATCGATGAC ACTCCCGAGC TGTTCGCTCT TATCGGCAGC 1500 1501 CAGAACCGTG CCCAGAAACT TCTTGCCTAC TTGGGTGATG TCGCCGTTAA CGGCAGCAGC 1560 1561 ATCAAGGGCC AGATCGGTGA GCCTAAGCTC AAGGGCGAGA TCATCAAGCC TACCCTGCTG 1620 1621 GACGATGCCG GTAAGCCGAT TGACGTGAGC GTTCCCTGCG CCCAGGGTTG GAAGCAGATC 1680 1681 ATCGACCGTG AAGGTCCCGC GGCTTTTGCC AAGGCTGTCC GTGCCAACAA GGGTTGCTTG 1740 1741 ATTATGGACA CCACCTGGCG TGATGCCCAC CAGTCGCTGT TGGCTACTCG TGTCCGCACG 1800 1801 ATCGATCTGC TGAACATCGC CAAGGAAACC AGTCACGCGT ACGCCAACGC TTACAGTTTG 1860 1861 GAATGCTGGG GTGGTGCCAC TTTCGATGTC GCCATGCGCT TCCTCTACGA GGATCCCTGG 1920 1921 GACCGTCTGC GCAAGCTGCG CAAGGCCGTG CCCAACATTC CCTTCCAGAT GCTGCTCCGC 1980 1981 GGTGCCAACG GGGTCGCCTA CTCGTCTCTT CCCGACAACG CCATTTACCA CTTCTGCAAG 2040 2041 CAGGCCAAGA AGTGCGGTGT CGACATCTTC CGTGTTTTCG ATGCGCTCAA CGACGTCGAC 2100 2101 CAGCTCGAGG TCGGTATCAA GGCTGTGCAG GCCGCCGAGG GTGTCGTCGA GGCCACCATC 2160 2161 TGCTACAGCG GAGACATGCT GAACCCCAAG AAGAAGTACA ACCTCGAGTA TTACCTGGCG 2220 2221 TTGGTGGACA AGATTGTCAA GCTCAACCCC CACATTCTTG GTATCAAGGA TATGGCCGGT 2280 2281 GTGTTGAAGC CCCAGGCCGC GCGCCTGCTG GTTGGCTCCA TCCGTGAGCG CTACCCCGAC 2340 2341 CTTCCCATCC ACGTCCACAC CCACGACTCT GCCGGTACTG GTGTGGCCTC CATGGTTGCC 2400 2401 TGCGCTCAGG CCGGCGCTGA CGCCGTCGAC GCCGCCACCG ACAGCATGTC CGGTATGACG 2460 2461 TCTCAGCCCA GCGTTGGTGC TATCCTTGCT TCTCTCGAGG GCACCGAGCA CGACCCCAAG 2520 2521 CTCAATCTGG CCCACGTTCG TGCCATTGAC TCCTATTGGC AGCAGCTGCG CTTGCTGTAC 2580 2581 TCGCCGTTCG AGGCTGGTCT GACCGGCCCT GACCCTGAGG TCTACGAGCA CGAAATTCCC 2640 2641 GGTGGTCAGC TGACCAACCT CCTCTTCCAG GCCAGTCAGC TCGGCCTGGG TCAGCAGTGG 2700 2701 GCCGAGACCA AGAAGGCATA TGAGTCGGCC AACGACCTGC TCGGCGACAT TGTCAAGGTC 2760 2761 ACCCCCACCT CCAAGGTTGT CGGTGACTTG GCTCAGTTCA TGGTCTCCAA CAAGCTGACT 2820 2821 CCCGAGGACG TTGTCGCCCG TGCTGGCGAG CTGGACTTCC CCGGCTCTGT CCTTGAATTC 2880 2881 CTCGAGGGTC TCATGGGCCA GCCCTTCGGT GGCTTCCCCG AGCCTCTGCG ATCCAAGGCT 2940 2941 CTGCGTGGCC GCCGCAAGCT CGACAAGCGC CCCGGTCTCT ACCTGGAGCC TCTGGACCTG 3000 3001 GCCAAGATCA AGAACCAGAT TCGGGAGAAG TATGGCTCCG CCACTGAGTA CGACGTGGCC 3060 3061 AGTTACGCCA TGTACCCCAA GGTCTTTGAG GACTACAAGA AGTTCGTGCA GAAGTTTGGT 3120 3121 GATCTCTCCA TCCTGCCTAC CCGCTACTTC CTGGCCAAGC CCGAGATCGG CGAGGAATTC 3180 3181 CACGTAGAGC TGGAGCAGGG TAAGGTCCTG ATCCTCAAGT TGCTGGCTAT CGGCCCCCTG 3240 3241 TCCGAGCAGA CCGGTCAGCG TGAGGTCTTC TACGAGGTCA ATGGTGAGGT CCGTCAGGTC 3300 3301 ACCGTCGACG ACAACAAGGC CTCTGTCGAT AACACCGCCC GCCCCAAGGC CGACATTGGC 3360 3361 GACAGCAGCC AAATCGGTGC TCCCATGAGC GGTGTCGTCG TTGAAATCCG TGTCCACGAA 3420 3421 GGCTCGGAGG TCAAGAAGGG TGACCCCGTT GCCGTTCTGA GCGCCATGAA GATGGAAATG 3480 3481 GTTATCTCTG CTCCTCACAG CGGAAAGGTC TCTGGCCTGC TCGTCAAGGA AGGCGATTCC 3540 3541 GTTGATGGCC AGGACCTCAT TTGTAAGATC GCCAAGGCAT AG 3582 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | Biotin binding | |
Molecular Function | Metal ion binding | |
Molecular Function | Pyruvate carboxylase activity | |
Biological Process | Gluconeogenesis | |
Biological Process | Pyruvate metabolic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Hos-a962 | Homo sapiens | 0.0 | 1237 | undefined |
| LLPS-Mum-a947 | Mus musculus | 0.0 | 1246 | undefined |