LLPS-Art-2723
MAPKKK3
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitogen-activated protein kinase kinase kinase 3; MAP3K alpha protein kinase; AtMAP3Kalpha |
| Gene Name: | MAPKKK3, MAP3KA, At1g53570, F22G10.18, T3F20.12 |
| Ensembl Gene: | AT1G53570 |
| Ensembl Protein: | AT1G53570.6 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT1G53570.6 | AT1G53570.6 |
| Ensembl | AT1G53570.5 | AT1G53570.5 |
| Ensembl | AT1G53570.7 | AT1G53570.7 |
| Ensembl | AT1G53570.4 | AT1G53570.4 |
| Ensembl | AT1G53570.2 | AT1G53570.2 |
| Ensembl | AT1G53570.3 | AT1G53570.3 |
| Ensembl | AT1G53570.1 | AT1G53570.1 |
| UniProt | F4HRJ4, M3K3A_ARATH, F4HRJ5, F4HRJ8, O82649, Q56ZS2, Q8W582, Q9LPH2, Q9ZRF7 | |
| GeneBank | AF419572, AY140005, AC018748, U58918, AK220889, AC024260, CP002684, BT002598, AJ010090 | AAD10848.1, AEE32964.1, CAA08994.1, AAL31904.1, BAD94298.1, AAG51965.1, AEE32962.1, AEE32961.1, AAM98147.1, AEE32963.1, AAF78433.1, AEE32960.1, AAO00958.1 |
| RefSeq | NM_001036104.2, NM_001198282.1, NM_001198283.1, NM_104235.4, NM_179472.3 | NP_001031181.1, NP_001185211.1, NP_001185212.1, NP_564635.1, NP_849803.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MPTWWGRKSC KNKDDNHRGI ISTDRDIKSS AVVVDPPLTP TRGGTPRCSR EFAGASSAFS 60 61 GFDSDSTEKK GHPLPRPLLS PVSIHHQDHV SGSTSGSTSV SSVSSSGSAD DQSQLVASRG 120 121 RGDVKFNVAA APRSPERVSP KAATITTRPT SPRHQRLSGV VSLESSTGRN DDGRSSSECH 180 181 PLPRPPTSPT SPSAVHGSRI GGGYETSPSG FSTWKKGKFL GSGTFGQVYL GFNSEKGKMC 240 241 AIKEVKVISD DQTSKECLKQ LNQEINLLNQ LCHPNIVQYY GSELSEETLS VYLEYVSGGS 300 301 IHKLLKDYGS FTEPVIQNYT RQILAGLAYL HGRNTVHRDI KGANILVDPN GEIKLADFGM 360 361 AKHVTAFSTM LSFKGSPYWM APEVVMSQNG YTHAVDIWSL GCTILEMATS KPPWSQFEGV 420 421 AAIFKIGNSK DTPEIPDHLS NDAKNFIRLC LQRNPTVRPT ASQLLEHPFL RNTTRVASTS 480 481 LPKDFPPRSY DGNFSLQPTR EPYPGRLSHD NYAKQPLSRT IKSPSRENVR AITSLPVSPC 540 541 SSPLRQLGPA YKSCFLSPPH PSYAFPGQDS GYNLAEFAAS PFRMKKDAMM EPSSFRTQTP 600 601 NSPLRSRLV 609 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGCCTACTT GGTGGGGAAG AAAGTCCTGC AAGAACAAGG ACGATAATCA CAGAGGAATC 60 61 ATCTCCACAG ATAGAGATAT CAAGAGCTCT GCTGTTGTTG TTGATCCTCC TCTCACTCCT 120 121 ACTCGTGGTG GTACACCTCG TTGCAGTCGT GAATTCGCTG GAGCTTCTTC TGCTTTCTCT 180 181 GGTTTTGACT CTGATTCTAC CGAGAAGAAA GGTCACCCTC TTCCTCGTCC TTTGCTCTCT 240 241 CCTGTTTCGA TCCATCATCA AGATCATGTA AGCGGATCCA CTTCTGGATC TACATCTGTT 300 301 TCTAGCGTTA GCTCATCTGG ATCAGCTGAT GATCAGAGTC AACTTGTTGC TTCTAGGGGT 360 361 CGTGGTGATG TGAAATTCAA TGTAGCAGCA GCACCACGTA GTCCTGAGAG AGTTTCTCCA 420 421 AAGGCAGCTA CTATTACTAC TAGGCCCACG TCTCCACGGC ATCAGCGTTT GTCTGGAGTT 480 481 GTGAGCTTAG AGTCTTCTAC AGGGAGGAAT GATGATGGAA GGTCCTCCTC TGAGTGTCAT 540 541 CCTTTGCCTC GACCACCTAC TTCTCCTACA AGCCCTTCTG CTGTGCATGG TTCCAGGATT 600 601 GGAGGAGGCT ACGAGACCTC TCCTTCGGGG TTTTCCACGT GGAAAAAAGG GAAATTTCTT 660 661 GGGAGTGGCA CCTTTGGTCA AGTCTATCTT GGTTTCAACA GTGAGAAAGG GAAAATGTGT 720 721 GCTATTAAAG AGGTCAAGGT CATTTCTGAC GATCAAACAT CAAAAGAATG TCTGAAGCAA 780 781 CTAAATCAGG AGATAAATTT GCTTAACCAG CTTTGTCATC CGAATATTGT CCAGTATTAC 840 841 GGAAGTGAAC TGAGTGAAGA AACCTTGTCC GTCTACTTGG AGTACGTGTC AGGTGGTTCA 900 901 ATCCATAAAC TACTTAAGGA TTATGGTTCT TTCACTGAAC CCGTTATCCA AAACTACACG 960 961 CGGCAGATTC TTGCTGGGCT TGCCTATTTA CATGGACGAA ATACAGTACA TAGGGACATC 1020 1021 AAAGGAGCAA ATATATTAGT GGATCCGAAT GGTGAAATCA AGTTGGCAGA CTTTGGGATG 1080 1081 GCCAAACATG TAACAGCCTT TTCTACTATG CTTTCTTTTA AAGGGAGTCC TTACTGGATG 1140 1141 GCACCCGAGG TTGTGATGAG CCAAAATGGC TACACTCATG CAGTCGATAT CTGGAGTTTG 1200 1201 GGTTGTACTA TTCTGGAAAT GGCAACATCA AAGCCACCTT GGAGCCAGTT TGAAGGGGTT 1260 1261 GCTGCGATTT TCAAAATCGG AAACAGTAAA GACACCCCGG AAATACCTGA TCACCTTTCA 1320 1321 AATGATGCAA AGAATTTTAT AAGGCTTTGT CTGCAACGAA ATCCGACAGT ACGTCCTACA 1380 1381 GCTTCTCAGC TTCTAGAACA CCCTTTTCTA CGTAACACAA CAAGAGTGGC TAGTACTAGT 1440 1441 TTGCCCAAAG ACTTCCCCCC ACGTTCCTAT GATGGAAACT TCTCACTGCA GCCTACAAGG 1500 1501 GAACCCTATC CAGGGAGACT GAGCCATGAT AATTATGCAA AACAGCCATT GTCTAGAACT 1560 1561 ATAAAGAGCC CGAGGTAA 1578 |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| PTM | ||||
| EPSD | ||||
| Interaction | ||||
| iRefIndex | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| iEKPD | ||||
| Localization | ||||
| COMPARTMENTS | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-2598 | Arabidopsis lyrata | 93.77 | 0.0 | 1008 |
| LLPS-Orp-0777 | Oryza punctata | 73.21 | 4e-126 | 395 |
| LLPS-Bro-1271 | Brassica oleracea | 68.64 | 0.0 | 713 |
| LLPS-Brr-2774 | Brassica rapa | 67.41 | 0.0 | 694 |
| LLPS-Gor-2617 | Gossypium raimondii | 63.67 | 0.0 | 587 |
| LLPS-Glm-2532 | Glycine max | 62.4 | 4e-176 | 520 |
| LLPS-Met-1935 | Medicago truncatula | 61.4 | 2e-168 | 504 |
| LLPS-Mua-2223 | Musa acuminata | 60.7 | 1e-137 | 426 |
| LLPS-Hov-2008 | Hordeum vulgare | 58.46 | 8e-94 | 303 |
| LLPS-Lep-1410 | Leersia perrieri | 58.45 | 4e-143 | 439 |
| LLPS-Tru-2080 | Triticum urartu | 58.09 | 4e-92 | 301 |
| LLPS-Via-1496 | Vigna angularis | 57.94 | 1e-165 | 489 |
| LLPS-Vir-1833 | Vigna radiata | 55.06 | 0.0 | 563 |
| LLPS-Sob-2360 | Sorghum bicolor | 53.94 | 6e-134 | 410 |
| LLPS-Thc-1133 | Theobroma cacao | 52.83 | 6e-83 | 280 |
| LLPS-Tra-3065 | Triticum aestivum | 52.27 | 3e-81 | 276 |
| LLPS-Ori-1585 | Oryza indica | 51.89 | 3e-81 | 276 |
| LLPS-Orr-2425 | Oryza rufipogon | 51.56 | 3e-125 | 398 |
| LLPS-Zem-0879 | Zea mays | 51.52 | 5e-81 | 275 |
| LLPS-Orm-1518 | Oryza meridionalis | 51.02 | 2e-120 | 389 |
| LLPS-Orb-1505 | Oryza barthii | 51.02 | 3e-120 | 388 |
| LLPS-Orni-0662 | Oryza nivara | 51.02 | 5e-120 | 387 |
| LLPS-Orgl-1860 | Oryza glumaepatula | 51.02 | 2e-120 | 389 |
| LLPS-Brd-2373 | Brachypodium distachyon | 50.9 | 1e-81 | 277 |
| LLPS-Ors-2042 | Oryza sativa | 50.79 | 4e-120 | 384 |
| LLPS-Org-1451 | Oryza glaberrima | 50.79 | 1e-121 | 388 |
| LLPS-Sei-1386 | Setaria italica | 50.76 | 1e-79 | 271 |
| LLPS-Orbr-1114 | Oryza brachyantha | 50.68 | 6e-123 | 392 |
| LLPS-Asf-0918 | Aspergillus flavus | 47.09 | 4e-55 | 193 |
| LLPS-Ved-1304 | Verticillium dahliae | 46.67 | 1e-61 | 228 |
| LLPS-Nec-1293 | Neurospora crassa | 46.67 | 1e-63 | 234 |
| LLPS-Fuo-0191 | Fusarium oxysporum | 46.47 | 5e-65 | 228 |
| LLPS-Asn-0738 | Aspergillus nidulans | 46.45 | 3e-51 | 196 |
| LLPS-Cog-1135 | Colletotrichum gloeosporioides | 46.3 | 2e-62 | 229 |
| LLPS-Cogr-0117 | Colletotrichum graminicola | 46.3 | 3e-62 | 229 |
| LLPS-Trr-1292 | Trichoderma reesei | 45.93 | 5e-62 | 229 |
| LLPS-Trv-1383 | Trichoderma virens | 45.93 | 5e-62 | 229 |
| LLPS-Coo-0271 | Colletotrichum orbiculare | 45.93 | 5e-61 | 226 |
| LLPS-Map-0011 | Magnaporthe poae | 45.72 | 8e-63 | 231 |
| LLPS-Fus-0913 | Fusarium solani | 45.71 | 1e-62 | 231 |
| LLPS-Gag-0603 | Gaeumannomyces graminis | 45.56 | 5e-62 | 229 |
| LLPS-Fuv-0909 | Fusarium verticillioides | 45.42 | 5e-57 | 214 |
| LLPS-Mao-0159 | Magnaporthe oryzae | 45.35 | 2e-61 | 227 |
| LLPS-Ast-0995 | Aspergillus terreus | 45.15 | 3e-62 | 229 |
| LLPS-Asc-0810 | Aspergillus clavatus | 45.15 | 5e-62 | 229 |
| LLPS-Beb-1013 | Beauveria bassiana | 45.07 | 6e-62 | 229 |
| LLPS-Pyt-1314 | Pyrenophora teres | 44.98 | 7e-63 | 231 |
| LLPS-Lem-0986 | Leptosphaeria maculans | 44.98 | 6e-63 | 232 |
| LLPS-Scf-1980 | Scleropages formosus | 44.94 | 6e-60 | 206 |
| LLPS-Scs-1084 | Sclerotinia sclerotiorum | 44.81 | 1e-60 | 225 |
| LLPS-Nef-1291 | Neosartorya fischeri | 44.78 | 5e-62 | 229 |
| LLPS-Abg-1683 | Absidia glauca | 44.78 | 1e-63 | 233 |
| LLPS-Sac-0160 | Saccharomyces cerevisiae | 44.68 | 1e-65 | 239 |
| LLPS-Asfu-1652 | Aspergillus fumigatus | 44.65 | 3e-61 | 226 |
| LLPS-Spr-0719 | Sporisorium reilianum | 44.57 | 2e-62 | 231 |
| LLPS-Asni-0960 | Aspergillus niger | 44.57 | 7e-63 | 231 |
| LLPS-Miv-0701 | Microbotryum violaceum | 44.44 | 2e-60 | 224 |
| LLPS-Usm-0886 | Ustilago maydis | 43.82 | 1e-61 | 228 |
| LLPS-Pug-0845 | Puccinia graminis | 43.7 | 1e-63 | 231 |
| LLPS-Aso-0608 | Aspergillus oryzae | 43.66 | 4e-61 | 226 |
| LLPS-Asg-0750 | Ashbya gossypii | 43.55 | 1e-65 | 239 |
| LLPS-Scj-0499 | Schizosaccharomyces japonicus | 43.53 | 6e-66 | 238 |
| LLPS-Blg-1055 | Blumeria graminis | 43.38 | 1e-60 | 225 |
| LLPS-Tum-1535 | Tuber melanosporum | 43.33 | 2e-59 | 221 |
| LLPS-Viv-1902 | Vitis vinifera | 43.28 | 2e-54 | 206 |
| LLPS-Zyt-1287 | Zymoseptoria tritici | 43.2 | 1e-56 | 198 |
| LLPS-Yal-0138 | Yarrowia lipolytica | 43.12 | 4e-62 | 229 |
| LLPS-Scc-0435 | Schizosaccharomyces cryophilus | 43.03 | 4e-51 | 195 |
| LLPS-Mel-0499 | Melampsora laricipopulina | 42.8 | 4e-57 | 199 |
| LLPS-Scp-0000 | Schizosaccharomyces pombe | 42.52 | 5e-53 | 200 |
| LLPS-Phn-1189 | Phaeosphaeria nodorum | 42.32 | 2e-54 | 206 |
| LLPS-Brn-1417 | Brassica napus | 42.07 | 4e-53 | 202 |
| LLPS-Pytr-1115 | Pyrenophora triticirepentis | 41.95 | 3e-54 | 205 |
| LLPS-Hea-1094 | Helianthus annuus | 41.95 | 1e-52 | 201 |
| LLPS-Crn-1306 | Cryptococcus neoformans | 41.94 | 1e-55 | 210 |
| LLPS-Prp-1369 | Prunus persica | 41.33 | 4e-52 | 199 |
| LLPS-Dos-0152 | Dothistroma septosporum | 40.94 | 6e-57 | 214 |
| LLPS-Cis-0713 | Ciona savignyi | 40.89 | 4e-50 | 192 |
| LLPS-Mae-2302 | Manihot esculenta | 40.71 | 4e-53 | 202 |
| LLPS-Nia-0113 | Nicotiana attenuata | 40.64 | 9e-53 | 201 |
| LLPS-Sol-2247 | Solanum lycopersicum | 40.64 | 4e-53 | 202 |
| LLPS-Kop-1060 | Komagataella pastoris | 40.62 | 5e-62 | 228 |
| LLPS-Put-0431 | Puccinia triticina | 40.45 | 1e-50 | 192 |
| LLPS-Chr-1491 | Chlamydomonas reinhardtii | 40.07 | 2e-56 | 212 |
| LLPS-Php-2124 | Physcomitrella patens | 39.93 | 3e-51 | 196 |
| LLPS-Anc-3736 | Anolis carolinensis | 38.15 | 4e-50 | 193 |
| LLPS-Leo-0638 | Lepisosteus oculatus | 38.06 | 2e-50 | 194 |
| LLPS-Amt-1439 | Amborella trichopoda | 37.98 | 1e-51 | 194 |
| LLPS-Phv-2354 | Phaseolus vulgaris | 37.91 | 1e-53 | 199 |
| LLPS-Dar-4255 | Danio rerio | 37.78 | 1e-49 | 191 |
| LLPS-Osl-0906 | Ostreococcus lucimarinus | 37.78 | 2e-50 | 181 |
| LLPS-Cus-2213 | Cucumis sativus | 37.69 | 9e-51 | 191 |
| LLPS-Fia-1511 | Ficedula albicollis | 37.5 | 6e-50 | 192 |
| LLPS-Tag-2289 | Taeniopygia guttata | 37.5 | 5e-50 | 192 |
| LLPS-Bot-1189 | Bos taurus | 37.5 | 2e-50 | 194 |
| LLPS-Myl-1140 | Myotis lucifugus | 37.41 | 1e-50 | 194 |
| LLPS-Pot-2561 | Populus trichocarpa | 37.18 | 4e-50 | 189 |
| LLPS-Hos-2935 | Homo sapiens | 37.13 | 3e-50 | 193 |
| LLPS-Pat-4351 | Pan troglodytes | 37.13 | 3e-50 | 193 |
| LLPS-Urm-2128 | Ursus maritimus | 37.13 | 8e-50 | 192 |
| LLPS-Pap-2159 | Pan paniscus | 37.13 | 6e-50 | 192 |
| LLPS-Fec-1765 | Felis catus | 37.13 | 3e-50 | 193 |
| LLPS-Man-4767 | Macaca nemestrina | 37.13 | 5e-50 | 192 |
| LLPS-Loa-4383 | Loxodonta africana | 37.13 | 3e-50 | 193 |
| LLPS-Otg-0907 | Otolemur garnettii | 37.13 | 4e-50 | 193 |
| LLPS-Orc-1886 | Oryctolagus cuniculus | 37.13 | 4e-50 | 192 |
| LLPS-Rhb-1237 | Rhinopithecus bieti | 37.13 | 4e-50 | 193 |
| LLPS-Caf-0654 | Canis familiaris | 37.13 | 2e-50 | 194 |
| LLPS-Cap-4146 | Cavia porcellus | 37.13 | 4e-50 | 193 |
| LLPS-Eqc-4381 | Equus caballus | 37.13 | 2e-50 | 194 |
| LLPS-Mam-3847 | Macaca mulatta | 37.13 | 5e-50 | 192 |
| LLPS-Gaga-1379 | Gallus gallus | 37.13 | 1e-49 | 191 |
| LLPS-Cas-3194 | Carlito syrichta | 37.13 | 4e-50 | 192 |
| LLPS-Nol-1371 | Nomascus leucogenys | 37.13 | 4e-50 | 193 |
| LLPS-Ict-4624 | Ictidomys tridecemlineatus | 37.13 | 4e-50 | 193 |
| LLPS-Maf-4310 | Macaca fascicularis | 37.13 | 2e-50 | 194 |
| LLPS-Mum-0925 | Mus musculus | 37.13 | 3e-50 | 193 |
| LLPS-Mea-1458 | Mesocricetus auratus | 37.13 | 3e-50 | 193 |
| LLPS-Ora-1534 | Ornithorhynchus anatinus | 37.13 | 7e-50 | 192 |
| LLPS-Chs-4742 | Chlorocebus sabaeus | 37.13 | 5e-50 | 192 |
| LLPS-Sus-0239 | Sus scrofa | 37.13 | 3e-50 | 193 |
| LLPS-Cea-3475 | Cercocebus atys | 37.13 | 3e-50 | 193 |
| LLPS-Aon-1996 | Aotus nancymaae | 37.13 | 3e-50 | 193 |
| LLPS-Gog-3905 | Gorilla gorilla | 37.13 | 5e-50 | 192 |
| LLPS-Fud-2494 | Fukomys damarensis | 37.13 | 4e-50 | 192 |
| LLPS-Caj-2588 | Callithrix jacchus | 37.13 | 3e-50 | 193 |
| LLPS-Dio-3007 | Dipodomys ordii | 37.13 | 3e-50 | 193 |
| LLPS-Ran-4366 | Rattus norvegicus | 37.13 | 2e-50 | 194 |
| LLPS-Mal-2755 | Mandrillus leucophaeus | 37.13 | 5e-50 | 192 |
| LLPS-Paa-3119 | Papio anubis | 37.13 | 3e-50 | 193 |
| LLPS-Mup-2779 | Mustela putorius furo | 37.13 | 4e-50 | 192 |
| LLPS-Aim-2905 | Ailuropoda melanoleuca | 37.13 | 6e-50 | 192 |
| LLPS-Poa-0454 | Pongo abelii | 37.04 | 8e-50 | 192 |
| LLPS-Icp-1181 | Ictalurus punctatus | 36.9 | 1e-49 | 192 |
| LLPS-Mod-2880 | Monodelphis domestica | 36.76 | 1e-49 | 191 |