LLPS-Art-2658
GDI2

▼ OVERVIEW

Status: Unreviewed
Protein Name: Guanosine nucleotide diphosphate dissociation inhibitor 2
Gene Name: GDI2, At3g59920, F24G16.190
Ensembl Gene: AT3G59920
Ensembl Protein: AT3G59920.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
OthersPredicted from orthologs(View)

▼ FUNCTION

Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDEEYEVIVL  GTGLKECILS  GLLSVDGVKV  LHMDRNDYYG  GESTSLNLNQ  LWKKFRGEEK  60
61    APEHLGASRD  YNVDMMPKFM  MGNGKLVRTL  IHTDVTKYLS  FKAVDGSYVF  VKGKVQKVPA  120
121   TPMEALKSSL  MGIFEKRRAG  KFFSFVQEYD  EKDPKTHDGM  DLTRVTTKEL  IAKYGLDGNT  180
181   IDFIGHAVAL  HTNDQHLDQP  AFDTVMRMKL  YAESLARFQG  TSPYIYPLYG  LGELPQAFAR  240
241   LSAVYGGTYM  LNKPECKVEF  DEGGKVIGVT  SEGETAKCKK  IVCDPSYLPN  KVRKIGRVAR  300
301   AIAIMSHPIP  NTNDSHSVQV  IIPQKQLARK  SDMYVFCCSY  SHNVAPKGKF  IAFVSTDAET  360
361   DNPQTELKPG  TDLLGPVDEI  FFDMYDRYEP  VNEPELDNCF  ISTSYDATTH  FETTVADVLN  420
421   MYTLITGKQL  DLSVDLSAAS  AAEE  444
Nucleotide CDS Sequence (FASTA)
1     ATGGATGAAG  AGTACGAGGT  TATTGTTCTC  GGCACCGGTC  TCAAGGAGTG  TATCCTCAGC  60
61    GGTCTCCTTT  CCGTCGATGG  TGTCAAGGTG  CTTCACATGG  ACAGGAATGA  CTACTATGGT  120
121   GGAGAATCAA  CTTCCCTTAA  TCTCAATCAG  CTTTGGAAGA  AGTTCAGGGG  AGAAGAGAAG  180
181   GCTCCTGAGC  ATTTAGGCGC  TAGCCGGGAT  TACAATGTTG  ACATGATGCC  TAAGTTTATG  240
241   ATGGGAAATG  GCAAGCTTGT  TCGTACCCTT  ATTCATACAG  ATGTTACAAA  GTATTTGTCC  300
301   TTCAAAGCTG  TTGATGGAAG  CTATGTTTTC  GTCAAAGGAA  AGGTTCAAAA  GGTGCCAGCT  360
361   ACTCCTATGG  AGGCCCTGAA  ATCTTCTCTC  ATGGGCATAT  TTGAGAAACG  TCGAGCCGGC  420
421   AAGTTTTTCA  GTTTTGTTCA  AGAATACGAT  GAGAAGGACC  CAAAAACACA  CGATGGAATG  480
481   GATTTGACCA  GAGTTACAAC  AAAGGAACTG  ATTGCGAAAT  ATGGTCTTGA  TGGCAACACT  540
541   ATTGACTTTA  TTGGTCACGC  AGTGGCACTT  CACACGAATG  ACCAACATCT  CGACCAACCC  600
601   GCCTTTGATA  CTGTAATGAG  AATGAAGCTC  TATGCGGAAT  CTCTTGCACG  TTTCCAAGGA  660
661   ACATCTCCAT  ATATTTATCC  TCTCTATGGG  TTGGGAGAAC  TACCCCAGGC  ATTTGCACGA  720
721   CTTAGTGCTG  TCTATGGTGG  CACATATATG  TTGAACAAAC  CTGAGTGCAA  GGTAGAGTTT  780
781   GACGAGGGAG  GTAAGGTTAT  TGGTGTAACA  TCTGAGGGAG  AGACTGCTAA  ATGCAAAAAG  840
841   ATTGTGTGTG  ACCCTTCATA  CCTGCCGAAC  AAGGTTAGGA  AGATTGGCAG  GGTTGCTCGG  900
901   GCCATCGCCA  TTATGAGCCA  CCCGATTCCG  AACACCAATG  ATTCTCACTC  AGTGCAGGTC  960
961   ATCATACCCC  AGAAACAGTT  GGCCCGCAAA  TCGGATATGT  ATGTCTTCTG  TTGTTCGTAC  1020
1021  TCCCACAACG  TTGCTCCCAA  GGGAAAATTC  ATTGCATTTG  TGTCTACAGA  TGCAGAGACT  1080
1081  GATAACCCTC  AAACCGAACT  AAAGCCTGGA  ACTGATCTTT  TGGGTCCTGT  TGATGAGATA  1140
1141  TTCTTCGACA  TGTATGATAG  ATACGAGCCT  GTCAACGAGC  CAGAGTTGGA  CAACTGCTTT  1200
1201  ATTTCAACGA  GCTATGATGC  TACAACACAC  TTTGAGACAA  CTGTTGCGGA  TGTGTTGAAC  1260
1261  ATGTATACCC  TAATCACCGG  AAAGCAACTG  GACCTAAGTG  TTGACCTGAG  TGCCGCAAGT  1320
1321  GCTGCAGAGG  AATGA  1335

▼ KEYWORD

ID
Family
Complete proteome
GTPase activation
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apoplast
Cellular Component
Cytosol
Cellular Component
Plasmodesma
Molecular Function
GTPase activator activity
Molecular Function
Rab GDP-dissociation inhibitor activity
Biological Process
Protein transport
Biological Process
Small GTPase mediated signal transduction

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-1404Arabidopsis lyrata98.830.0 887
LLPS-Tru-0549Triticum urartu86.679e-0858.5
LLPS-Dac-1188Daucus carota85.980.0 783
LLPS-Hov-1619Hordeum vulgare85.550.0 778
LLPS-Orbr-1532Oryza brachyantha85.050.0 776
LLPS-Brd-0643Brachypodium distachyon85.050.0 778
LLPS-Orm-0991Oryza meridionalis84.810.0 773
LLPS-Orr-0790Oryza rufipogon84.810.0 770
LLPS-Pot-2549Populus trichocarpa84.810.0 774
LLPS-Sei-2244Setaria italica84.810.0 775
LLPS-Ori-1899Oryza indica84.810.0 773
LLPS-Ors-0897Oryza sativa84.580.0 775
LLPS-Orgl-1535Oryza glumaepatula84.580.0 775
LLPS-Orni-2195Oryza nivara84.580.0 775
LLPS-Org-0622Oryza glaberrima84.350.0 775
LLPS-Orp-0688Oryza punctata84.350.0 769
LLPS-Orb-2057Oryza barthii84.350.0 775
LLPS-Sob-0354Sorghum bicolor84.110.0 773
LLPS-Nia-2093Nicotiana attenuata84.110.0 766
LLPS-Zem-0936Zea mays81.920.0 760
LLPS-Viv-0233Vitis vinifera80.01e-68 221
LLPS-Gor-1527Gossypium raimondii79.440.0 728
LLPS-Mua-2403Musa acuminata79.020.0 729
LLPS-Mae-0680Manihot esculenta78.040.0 726
LLPS-Prp-1540Prunus persica77.80.0 722
LLPS-Lep-0400Leersia perrieri77.620.0 717
LLPS-Tra-2721Triticum aestivum77.620.0 727
LLPS-Glm-2346Glycine max77.570.0 716
LLPS-Bro-0614Brassica oleracea77.340.0 719
LLPS-Brr-2513Brassica rapa77.340.0 720
LLPS-Vir-1267Vigna radiata77.340.0 690
LLPS-Brn-2636Brassica napus77.340.0 721
LLPS-Php-1495Physcomitrella patens76.460.0 683
LLPS-Hea-1662Helianthus annuus75.290.0 709
LLPS-Sol-2510Solanum lycopersicum73.980.0 669
LLPS-Coc-0364Corchorus capsularis66.081e-69 224
LLPS-Chr-1249Chlamydomonas reinhardtii64.80.0 559
LLPS-Phv-2050Phaseolus vulgaris60.321e-73 237
LLPS-Mod-2400Monodelphis domestica57.941e-180 520
LLPS-Hos-2773Homo sapiens57.711e-180 520
LLPS-Gog-3686Gorilla gorilla57.711e-180 520
LLPS-Mam-1672Macaca mulatta57.482e-180 519
LLPS-Orc-1608Oryctolagus cuniculus57.480.0 520
LLPS-Dio-3794Dipodomys ordii57.482e-180 519
LLPS-Bot-3233Bos taurus57.480.0 520
LLPS-Mea-2717Mesocricetus auratus57.480.0 521
LLPS-Mum-3942Mus musculus57.243e-180 518
LLPS-Dar-3725Danio rerio57.219e-179 515
LLPS-Scf-2261Scleropages formosus57.013e-179 516
LLPS-Fud-3705Fukomys damarensis57.019e-180 517
LLPS-Asm-3168Astyanax mexicanus56.787e-175 513
LLPS-Myl-3992Myotis lucifugus56.631e-172 499
LLPS-Ova-3376Ovis aries56.424e-171 494
LLPS-Man-4059Macaca nemestrina56.283e-177 511
LLPS-Paa-3301Papio anubis56.283e-177 511
LLPS-Maf-4183Macaca fascicularis56.283e-177 511
LLPS-Cea-2374Cercocebus atys56.283e-177 511
LLPS-Aon-4622Aotus nancymaae56.284e-176 508
LLPS-Pap-1661Pan paniscus56.057e-177 510
LLPS-Pat-4326Pan troglodytes56.057e-177 510
LLPS-Chs-1768Chlorocebus sabaeus56.054e-176 508
LLPS-Poa-1434Pongo abelii55.813e-176 508
LLPS-Eqc-3658Equus caballus55.582e-173 501
LLPS-Gaga-3138Gallus gallus55.586e-172 504
LLPS-Rhb-1914Rhinopithecus bieti55.423e-168 487
LLPS-Fec-1725Felis catus55.355e-173 500
LLPS-Crn-0355Cryptococcus neoformans55.26e-168 487
LLPS-Ict-3259Ictidomys tridecemlineatus55.122e-172 499
LLPS-Mal-2620Mandrillus leucophaeus55.093e-168 489
LLPS-Caf-1422Canis familiaris54.942e-165 480
LLPS-Loa-3491Loxodonta africana54.884e-173 500
LLPS-Aim-1876Ailuropoda melanoleuca54.881e-169 493
LLPS-Sah-0846Sarcophilus harrisii54.882e-171 498
LLPS-Sus-4627Sus scrofa54.882e-170 493
LLPS-Nol-3953Nomascus leucogenys54.693e-170 493
LLPS-Anc-3514Anolis carolinensis54.692e-165 481
LLPS-Tag-3033Taeniopygia guttata54.684e-167 484
LLPS-Ran-4541Rattus norvegicus54.421e-172 499
LLPS-Ora-3151Ornithorhynchus anatinus54.355e-168 487
LLPS-Mel-0503Melampsora laricipopulina54.275e-167 485
LLPS-Cae-0396Caenorhabditis elegans54.262e-167 486
LLPS-Fia-3131Ficedula albicollis54.26e-165 479
LLPS-Caj-2693Callithrix jacchus54.11e-168 489
LLPS-Urm-2274Ursus maritimus53.922e-158 462
LLPS-Abg-0449Absidia glauca53.861e-168 489
LLPS-Meg-2440Meleagris gallopavo53.763e-167 485
LLPS-Anp-3373Anas platyrhynchos53.769e-133 394
LLPS-Pes-2829Pelodiscus sinensis53.732e-162 473
LLPS-Put-0321Puccinia triticina53.722e-161 474
LLPS-Mup-4570Mustela putorius furo53.683e-157 459
LLPS-Spr-1306Sporisorium reilianum53.615e-163 475
LLPS-Xet-1442Xenopus tropicalis53.61e-165 481
LLPS-Usm-0648Ustilago maydis53.449e-163 474
LLPS-Pug-1494Puccinia graminis53.123e-164 478
LLPS-Chc-0583Chondrus crispus52.914e-159 465
LLPS-Cas-2617Carlito syrichta52.883e-160 468
LLPS-Sac-1052Saccharomyces cerevisiae52.191e-158 463
LLPS-Cap-2519Cavia porcellus52.093e-159 464
LLPS-Fuv-1062Fusarium verticillioides52.08e-149 439
LLPS-Fuo-1254Fusarium oxysporum51.784e-149 440
LLPS-Tar-2140Takifugu rubripes51.673e-84 266
LLPS-Lac-2400Latimeria chalumnae51.543e-140 415
LLPS-Otg-3982Otolemur garnettii51.395e-155 454
LLPS-Beb-0425Beauveria bassiana50.896e-144 426
LLPS-Trv-0876Trichoderma virens50.672e-142 422
LLPS-Icp-3295Ictalurus punctatus50.471e-148 436
LLPS-Mao-1135Magnaporthe oryzae49.892e-140 417
LLPS-Leo-3243Lepisosteus oculatus45.213e-103 318
LLPS-Lem-1088Leptosphaeria maculans23.382e-1479.3