LLPS-Art-2449
KIN17

▼ OVERVIEW

Status: Unreviewed
Protein Name: KIN17-like protein
Gene Name: KIN17, At1g55460, T5A14.13
Ensembl Gene: AT1G55460
Ensembl Protein: AT1G55460.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nuclear speckle, NucleolusPredicted from orthologs(View)

▼ FUNCTION

Promotes the copper deficiency response by direct interaction with SPL7. Acts with SPL7 in a common pathway to promote copper-responsive genes and alleviate oxidative stress during copper-limiting periods. May promote SPL7 function when copper is limiting (PubMed:24335506). Participates in the control of general plant growth and development, and in the response to counteract the negative effects of UV radiation (PubMed:24713636).

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MGKNDFLTPK  AIANRIKAKG  LQKLRWYCQM  CQKQCRDENG  FKCHCMSESH  QRQMQVFGQN  60
61    PTRVVDGYSE  EFEQTFLDLM  RRSHRFSRIA  ATVVYNEYIN  DRHHVHMNST  EWATLTEFIK  120
121   HLGKTGKCKV  EETPKGWFIT  YIDRDSETLF  KERLKNKRVK  SDLAEEEKQE  REIQRQIERA  180
181   AEKLNGGGGE  GETSGNDEVV  DDGDDERKKD  EDLRLKSGVK  VGFALGGGVK  QVATGKERGE  240
241   SSKLLFGDEE  NDKVERGEKR  KRSGDSGRSE  KERRSALDEL  MKEEEKKKER  MNRKDYWLFE  300
301   GIIVKVMSKA  LAEKGYYKQK  GVVKKVIDNY  VGEIKMLDSK  HVLRVDQKEL  ETVLPQIGGM  360
361   VKIVNGAYRG  SNARLLGVDT  EKFCAKVQIE  KGVYDGRVIK  SIEYEDICKL  A  411
Nucleotide CDS Sequence (FASTA)
1     ATGGGTAAGA  ACGATTTTCT  AACCCCAAAG  GCGATTGCGA  ATCGAATTAA  AGCCAAAGGA  60
61    CTTCAAAAGC  TTCGATGGTA  TTGTCAGATG  TGTCAGAAAC  AATGCCGAGA  CGAGAATGGA  120
121   TTCAAGTGTC  ATTGTATGAG  CGAATCTCAC  CAGAGGCAGA  TGCAAGTTTT  TGGGCAGAAT  180
181   CCGACTCGTG  TTGTCGATGG  TTACTCTGAA  GAATTCGAGC  AGACGTTTCT  CGATCTGATG  240
241   AGGCGGAGCC  ACCGTTTCTC  TCGTATCGCT  GCCACTGTTG  TCTACAATGA  GTATATTAAC  300
301   GATAGACATC  ATGTTCACAT  GAATTCGACG  GAGTGGGCGA  CGTTGACGGA  GTTTATCAAG  360
361   CATCTTGGGA  AAACTGGTAA  GTGTAAGGTT  GAAGAAACTC  CTAAAGGTTG  GTTTATTACT  420
421   TATATAGATA  GAGATTCTGA  GACTTTGTTT  AAGGAGAGGT  TGAAGAATAA  GAGAGTTAAG  480
481   AGTGATTTAG  CTGAGGAGGA  GAAGCAAGAG  AGGGAGATTC  AGAGACAGAT  TGAGAGAGCT  540
541   GCTGAGAAAT  TGAATGGTGG  TGGTGGTGAA  GGTGAAACCA  GTGGTAATGA  TGAAGTTGTG  600
601   GATGATGGTG  ATGATGAGAG  GAAGAAAGAT  GAAGACTTGA  GGTTGAAGAG  TGGGGTCAAG  660
661   GTTGGATTTG  CTCTTGGTGG  AGGTGTTAAA  CAGGTTGCTA  CGGGTAAAGA  GAGAGGGGAA  720
721   AGCTCGAAAC  TTTTGTTTGG  GGATGAAGAG  AATGACAAGG  TTGAGAGAGG  GGAGAAGAGG  780
781   AAGAGAAGTG  GGGACTCCGG  GAGGAGCGAG  AAGGAGAGGA  GATCAGCTTT  GGATGAGTTG  840
841   ATGAAGGAGG  AAGAGAAGAA  GAAGGAGAGG  ATGAATCGGA  AAGATTACTG  GTTGTTCGAA  900
901   GGGATCATTG  TGAAGGTGAT  GAGTAAGGCT  TTGGCAGAGA  AAGGGTATTA  TAAGCAAAAA  960
961   GGTGTTGTGA  AGAAAGTGAT  TGATAATTAT  GTTGGGGAGA  TCAAAATGCT  TGATTCTAAA  1020
1021  CATGTGTTGA  GAGTTGATCA  AAAGGAGCTA  GAGACTGTGC  TTCCACAAAT  TGGAGGGATG  1080
1081  GTGAAGATAG  TGAATGGGGC  ATATCGTGGT  TCGAATGCAA  GGTTGTTGGG  TGTGGATACA  1140
1141  GAGAAGTTCT  GTGCTAAAGT  GCAGATCGAG  AAAGGTGTCT  ATGATGGAAG  AGTCATCAAG  1200
1201  TCCATTGAGT  ACGAGGACAT  ATGCAAACTT  GCTTAG  1236

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Metal-binding
Nucleus
Reference proteome
Stress response
Zinc
Zinc-finger

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nuclear speck
Cellular Component
Nucleus
Molecular Function
Double-stranded DNA binding
Molecular Function
Metal ion binding
Biological Process
Cellular response to copper ion starvation
Biological Process
Cellular response to DNA damage stimulus
Biological Process
DNA replication
Biological Process
Regulation of developmental growth

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Function
PIRSF
Localization
COMPARTMENTSNLSdb

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0227Arabidopsis lyrata93.690.0 662
LLPS-Coc-1787Corchorus capsularis90.28e-23 101
LLPS-Org-0184Oryza glaberrima82.824e-96 301
LLPS-Orm-1386Oryza meridionalis82.823e-92 300
LLPS-Orr-1239Oryza rufipogon82.826e-91 300
LLPS-Ors-0147Oryza sativa82.824e-96 301
LLPS-Orgl-1848Oryza glumaepatula82.822e-91 300
LLPS-Orni-1620Oryza nivara82.824e-96 301
LLPS-Orb-1442Oryza barthii82.825e-91 301
LLPS-Ori-0733Oryza indica82.824e-96 301
LLPS-Sei-1134Setaria italica82.213e-96 301
LLPS-Brr-2483Brassica rapa81.640.0 572
LLPS-Sob-2459Sorghum bicolor80.982e-95 299
LLPS-Brd-1630Brachypodium distachyon80.983e-94 296
LLPS-Tru-0303Triticum urartu80.374e-94 296
LLPS-Hov-1625Hordeum vulgare80.371e-93 296
LLPS-Tra-0952Triticum aestivum80.373e-94 296
LLPS-Bro-0703Brassica oleracea80.150.0 597
LLPS-Brn-3277Brassica napus79.810.0 550
LLPS-Xet-0609Xenopus tropicalis75.617e-38 146
LLPS-Prp-0728Prunus persica74.940.0 542
LLPS-Gor-1705Gossypium raimondii73.910.0 543
LLPS-Mae-2042Manihot esculenta73.720.0 539
LLPS-Pot-0563Populus trichocarpa72.640.0 530
LLPS-Thc-0253Theobroma cacao70.80.0 520
LLPS-Viv-0689Vitis vinifera70.561e-178 511
LLPS-Dac-0287Daucus carota69.760.0 523
LLPS-Met-1177Medicago truncatula69.710.0 518
LLPS-Glm-2394Glycine max69.711e-179 513
LLPS-Amt-1227Amborella trichopoda68.777e-173 496
LLPS-Chr-1531Chlamydomonas reinhardtii68.529e-78 254
LLPS-Orl-2245Oryzias latipes68.464e-72 238
LLPS-Nia-1965Nicotiana attenuata68.376e-177 507
LLPS-Phv-1554Phaseolus vulgaris68.361e-177 508
LLPS-Cus-1287Cucumis sativus68.191e-178 511
LLPS-Via-0635Vigna angularis68.183e-180 515
LLPS-Mod-2520Monodelphis domestica67.791e-71 236
LLPS-Sah-0834Sarcophilus harrisii67.791e-71 236
LLPS-Ora-1308Ornithorhynchus anatinus67.792e-71 238
LLPS-Sol-0694Solanum lycopersicum67.311e-175 503
LLPS-Sot-1732Solanum tuberosum67.073e-175 503
LLPS-Hea-1006Helianthus annuus66.591e-174 501
LLPS-Lep-1567Leersia perrieri66.281e-167 484
LLPS-Zem-1830Zea mays66.274e-166 480
LLPS-Orbr-1080Oryza brachyantha66.121e-166 482
LLPS-Ten-2872Tetraodon nigroviridis65.792e-71 236
LLPS-Lac-2469Latimeria chalumnae65.642e-73 241
LLPS-Mua-0303Musa acuminata65.462e-176 506
LLPS-Nol-3009Nomascus leucogenys65.035e-73 240
LLPS-Ict-3562Ictidomys tridecemlineatus65.032e-73 241
LLPS-Cas-1472Carlito syrichta65.032e-73 241
LLPS-Mam-2195Macaca mulatta65.033e-73 241
LLPS-Caf-0524Canis familiaris65.032e-73 241
LLPS-Poa-2021Pongo abelii65.032e-73 241
LLPS-Cap-0138Cavia porcellus65.032e-73 241
LLPS-Eqc-1150Equus caballus65.031e-71 238
LLPS-Orc-0362Oryctolagus cuniculus65.031e-73 242
LLPS-Man-3954Macaca nemestrina65.033e-73 241
LLPS-Hos-1175Homo sapiens65.032e-73 241
LLPS-Urm-0349Ursus maritimus65.031e-71 242
LLPS-Pap-0518Pan paniscus65.032e-73 241
LLPS-Pat-1703Pan troglodytes65.032e-73 241
LLPS-Fec-3303Felis catus65.031e-73 242
LLPS-Paa-2969Papio anubis65.033e-73 241
LLPS-Myl-2162Myotis lucifugus65.032e-73 241
LLPS-Ova-1215Ovis aries65.032e-73 241
LLPS-Mup-3177Mustela putorius furo65.032e-73 241
LLPS-Aim-2548Ailuropoda melanoleuca65.032e-73 241
LLPS-Dio-1169Dipodomys ordii65.032e-73 241
LLPS-Bot-0925Bos taurus65.032e-73 241
LLPS-Fud-4188Fukomys damarensis65.032e-73 241
LLPS-Caj-0510Callithrix jacchus65.032e-72 239
LLPS-Gog-4042Gorilla gorilla65.032e-73 241
LLPS-Leo-0800Lepisosteus oculatus65.032e-73 241
LLPS-Sus-2792Sus scrofa65.032e-73 241
LLPS-Aon-2694Aotus nancymaae65.032e-73 241
LLPS-Maf-0919Macaca fascicularis65.033e-73 241
LLPS-Chs-1339Chlorocebus sabaeus65.033e-73 241
LLPS-Otg-0383Otolemur garnettii64.423e-73 240
LLPS-Loa-0681Loxodonta africana64.427e-73 240
LLPS-Asm-3384Astyanax mexicanus64.425e-72 238
LLPS-Mea-2087Mesocricetus auratus64.422e-73 241
LLPS-Mal-3742Mandrillus leucophaeus63.978e-58 196
LLPS-Rhb-0848Rhinopithecus bieti63.82e-72 238
LLPS-Dar-1580Danio rerio63.81e-72 239
LLPS-Scf-0054Scleropages formosus63.81e-73 241
LLPS-Pof-2919Poecilia formosa63.193e-73 241
LLPS-Xim-1205Xiphophorus maculatus63.193e-73 241
LLPS-Gas-0613Galdieria sulphuraria62.342e-59 204
LLPS-Gaa-0500Gasterosteus aculeatus61.353e-71 235
LLPS-Cea-0539Cercocebus atys60.618e-63 213
LLPS-Cis-1268Ciona savignyi60.05e-61 208
LLPS-Cii-0679Ciona intestinalis58.715e-57 198
LLPS-Scj-0670Schizosaccharomyces japonicus56.381e-56 194
LLPS-Pes-2683Pelodiscus sinensis55.779e-35 137
LLPS-Php-1009Physcomitrella patens55.695e-148 433
LLPS-Mel-0608Melampsora laricipopulina55.261e-55 189
LLPS-Sem-1606Selaginella moellendorffii54.722e-139 411
LLPS-Drm-1709Drosophila melanogaster54.363e-57 199
LLPS-Abg-1655Absidia glauca53.951e-55 192
LLPS-Fuo-0946Fusarium oxysporum53.025e-50 178
LLPS-Cae-0988Caenorhabditis elegans52.743e-51 183
LLPS-Zyt-0501Zymoseptoria tritici52.353e-50 179
LLPS-Yal-0238Yarrowia lipolytica52.25e-54 186
LLPS-Gaga-1962Gallus gallus52.156e-51 181
LLPS-Osl-0407Ostreococcus lucimarinus51.922e-54 189
LLPS-Lem-0383Leptosphaeria maculans51.399e-47 168
LLPS-Chc-0623Chondrus crispus51.021e-49 179
LLPS-Ved-0559Verticillium dahliae51.013e-49 176
LLPS-Asf-0128Aspergillus flavus51.014e-51 181
LLPS-Aso-1428Aspergillus oryzae51.014e-51 181
LLPS-Orp-0600Oryza punctata50.798e-56 193
LLPS-Pytr-0644Pyrenophora triticirepentis50.693e-47 169
LLPS-Pyt-0106Pyrenophora teres50.693e-47 169
LLPS-Scc-0721Schizosaccharomyces cryophilus50.635e-51 180
LLPS-Coo-0461Colletotrichum orbiculare50.342e-47 171
LLPS-Dos-1325Dothistroma septosporum50.331e-48 174
LLPS-Gag-1231Gaeumannomyces graminis50.02e-48 174
LLPS-Pug-0171Puccinia graminis49.698e-53 186
LLPS-Mao-0896Magnaporthe oryzae49.694e-48 172
LLPS-Cogr-1494Colletotrichum graminicola49.666e-47 170
LLPS-Asfu-0385Aspergillus fumigatus49.661e-49 177
LLPS-Trv-0349Trichoderma virens49.668e-49 175
LLPS-Nef-0005Neosartorya fischeri49.667e-50 178
LLPS-Fus-1276Fusarium solani49.663e-48 173
LLPS-Trr-0833Trichoderma reesei49.662e-48 174
LLPS-Scp-0215Schizosaccharomyces pombe49.381e-51 181
LLPS-Map-1084Magnaporthe poae49.341e-48 175
LLPS-Crn-1114Cryptococcus neoformans49.083e-46 167
LLPS-Asc-0722Aspergillus clavatus48.995e-50 178
LLPS-Spr-1448Sporisorium reilianum48.71e-47 172
LLPS-Asn-0360Aspergillus nidulans48.325e-49 175
LLPS-Tum-0460Tuber melanosporum48.159e-49 174
LLPS-Blg-1081Blumeria graminis48.156e-49 175
LLPS-Usm-0545Ustilago maydis48.051e-46 169
LLPS-Anp-3300Anas platyrhynchos47.79e-107 327
LLPS-Cog-1271Colletotrichum gloeosporioides47.655e-44 162
LLPS-Phn-1371Phaeosphaeria nodorum47.332e-44 162
LLPS-Ast-0021Aspergillus terreus46.882e-25 108
LLPS-Asg-1053Ashbya gossypii46.542e-43 157
LLPS-Scs-0613Sclerotinia sclerotiorum46.32e-46 169
LLPS-Mum-0256Mus musculus46.151e-104 322
LLPS-Miv-1265Microbotryum violaceum46.11e-42 159
LLPS-Ran-3704Rattus norvegicus45.916e-100 310
LLPS-Tag-0730Taeniopygia guttata45.522e-105 324
LLPS-Kop-0874Komagataella pastoris45.291e-41 153
LLPS-Fia-0574Ficedula albicollis45.041e-104 322
LLPS-Tar-2997Takifugu rubripes44.793e-102 316
LLPS-Icp-2652Ictalurus punctatus44.633e-97 303
LLPS-Asni-0199Aspergillus niger44.445e-48 172
LLPS-Sac-1505Saccharomyces cerevisiae43.758e-28 114
LLPS-Scm-2420Scophthalmus maximus43.581e-94 296
LLPS-Beb-0956Beauveria bassiana43.211e-43 161
LLPS-Orn-2678Oreochromis niloticus43.12e-97 303
LLPS-Nec-0480Neurospora crassa42.677e-35 138
LLPS-Meg-0425Meleagris gallopavo41.162e-64 216
LLPS-Anc-1073Anolis carolinensis41.13e-79 255
LLPS-Cym-0066Cyanidioschyzon merolae32.51e-1375.5