LLPS-Art-1979
HOS15
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | WD40 repeat-containing protein HOS15; HIGH OSMOTIC STRESS GENE EXPRESSION 15 |
| Gene Name: | HOS15, At5g67320, K8K14.4 |
| Ensembl Gene: | AT5G67320 |
| Ensembl Protein: | AT5G67320.1 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Acts as repressor of cold stress-regulated gene expression. Interacts specifically with and promotes deacetylation of histone H4. Plays a role in gene regulation for plant acclimation and tolerance to cold stress. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT5G67320.1 | AT5G67320.1 |
| UniProt | Q9FN19, HOS15_ARATH, Q56Y40 | |
| GeneBank | AK221483, CP002688, AY143932, AY057698, AB007645 | AAL15328.1, BAD94649.1, AED98328.1, AAN28871.1, BAB09017.1 |
| RefSeq | NM_126132.4 | NP_201533.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSSLTSVELN FLVFRYLQES GFTHAAFTLG YEAGINKSNI DGNMVPPGAL IKFVQKGLQY 60 61 MEMEANLSNS EVDIDEDFSF FQPLDLISKD VKELQDMLRE KKRKERDMEK ERDRSKENDK 120 121 GVEREHEGDR NRAKEKDRHE KQKERERERE KLEREKERER EKIEREKERE REKMEREIFE 180 181 REKDRLKLEK EREIERERER EKIEREKSHE KQLGDADREM VIDQTDKEIA GDGSTGAEPM 240 241 DIVMTPTSQT SHIPNSDVRI LEGHTSEVCA CAWSPSASLL ASGSGDATAR IWSIPEGSFK 300 301 AVHTGRNINA LILKHAKGKS NEKSKDVTTL DWNGEGTLLA TGSCDGQARI WTLNGELIST 360 361 LSKHKGPIFS LKWNKKGDYL LTGSVDRTAV VWDVKAEEWK QQFEFHSGPT LDVDWRNNVS 420 421 FATSSTDSMI YLCKIGETRP AKTFTGHQGE VNCVKWDPTG SLLASCSDDS TAKIWNIKQS 480 481 TFVHDLREHT KEIYTIRWSP TGPGTNNPNK QLTLASASFD STVKLWDAEL GKMLCSFNGH 540 541 REPVYSLAFS PNGEYIASGS LDKSIHIWSI KEGKIVKTYT GNGGIFEVCW NKEGNKIAAC 600 601 FADNSVCVLD FRM 613 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCTTCAC TTACCTCCGT CGAATTGAAT TTTCTGGTTT TCCGATATCT TCAGGAATCA 60 61 GGGTTTACAC ACGCTGCATT CACTCTAGGT TATGAGGCAG GGATTAATAA ATCCAACATT 120 121 GATGGGAATA TGGTTCCACC TGGTGCTCTT ATCAAATTTG TTCAGAAAGG TCTTCAGTAC 180 181 ATGGAGATGG AAGCTAATTT GAGCAATAGT GAAGTGGACA TTGATGAGGA TTTCTCATTC 240 241 TTTCAACCCT TGGATCTGAT TTCAAAGGAT GTAAAGGAAC TGCAGGATAT GCTGAGGGAA 300 301 AAGAAGAGGA AAGAGAGGGA TATGGAGAAG GAAAGAGACA GATCTAAAGA AAACGATAAA 360 361 GGGGTTGAAC GAGAACATGA AGGAGATCGC AACCGAGCTA AGGAAAAGGA TAGGCACGAG 420 421 AAGCAGAAGG AACGAGAGAG GGAAAGGGAA AAATTGGAAC GTGAAAAGGA GAGGGAAAGA 480 481 GAGAAGATAG AACGAGAAAA GGAACGGGAA AGGGAGAAGA TGGAACGGGA AATATTTGAG 540 541 AGGGAGAAGG ATAGATTGAA ATTAGAGAAA GAAAGAGAAA TAGAACGGGA GAGGGAAAGA 600 601 GAGAAGATAG AGAGGGAAAA GAGCCATGAA AAACAGCTTG GAGATGCTGA TAGGGAAATG 660 661 GTTATTGACC AAACTGACAA AGAAATTGCT GGGGATGGTT CTACAGGCGC AGAACCTATG 720 721 GATATTGTTA TGACTCCCAC ATCTCAGACA AGTCACATTC CTAATTCTGA TGTGAGGATT 780 781 TTGGAAGGGC ATACTTCTGA GGTTTGTGCT TGCGCATGGA GTCCCTCAGC TTCACTTCTT 840 841 GCGTCAGGGT CTGGTGATGC AACAGCGCGA ATCTGGAGTA TTCCGGAAGG ATCATTCAAA 900 901 GCTGTGCATA CTGGTCGTAA TATCAACGCT TTAATCCTGA AGCATGCAAA AGGCAAGTCA 960 961 AACGAGAAGA GCAAGGATGT GACCACTCTT GACTGGAATG GTGAAGGGAC TTTACTTGCA 1020 1021 ACTGGTTCAT GTGATGGCCA AGCAAGAATC TGGACTTTAA ATGGTGAACT GATAAGTACT 1080 1081 CTTAGCAAAC ACAAGGGACC TATTTTTTCC CTTAAGTGGA ACAAGAAGGG GGACTATCTT 1140 1141 CTAACCGGTA GTGTTGATAG AACTGCTGTT GTTTGGGACG TAAAGGCAGA GGAGTGGAAG 1200 1201 CAACAATTTG AATTTCATTC AGGTCCAACA CTTGATGTTG ATTGGCGCAA CAATGTATCT 1260 1261 TTTGCAACGA GTTCCACGGA CAGCATGATC TACTTATGTA AGATTGGAGA AACTAGGCCT 1320 1321 GCCAAAACCT TTACTGGGCA TCAGGGTGAG GTCAACTGTG TGAAATGGGA TCCTACTGGT 1380 1381 TCATTATTGG CCTCATGCTC AGATGATAGT ACTGCTAAGA TATGGAATAT AAAACAAAGC 1440 1441 ACCTTTGTTC ATGACCTCCG AGAGCATACT AAGGAAATTT ATACAATCAG ATGGAGCCCT 1500 1501 ACAGGACCAG GAACTAACAA TCCTAACAAA CAGCTAACTC TTGCAAGTGC ATCATTTGAC 1560 1561 TCAACAGTAA AGCTATGGGA TGCAGAACTC GGGAAGATGC TCTGTAGTTT CAATGGACAC 1620 1621 AGGGAACCGG TTTACTCACT GGCGTTTAGT CCAAACGGGG AGTACATAGC GAGTGGGTCT 1680 1681 TTGGACAAAT CGATACACAT ATGGTCGATT AAAGAAGGTA AAATCGTAAA GACATACACA 1740 1741 GGAAATGGAG GGATATTCGA AGTGTGTTGG AACAAAGAAG GTAACAAAAT CGCAGCTTGC 1800 1801 TTCGCTGATA ACTCAGTTTG CGTTCTTGAT TTCAGAATGT AG 1842 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cul4-RING E3 ubiquitin ligase complex | |
Cellular Component | Histone deacetylase complex | |
Cellular Component | Nucleus | |
Molecular Function | Transcription corepressor activity | |
Biological Process | Histone deacetylation | |
Biological Process | Regulation of transcription by RNA polymerase II | |
Biological Process | Response to cold |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| PTM | ||||
| EPSD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| iEKPD | ||||
| Localization | ||||
| COMPARTMENTS | NLSdb | |||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-0859 | Arabidopsis lyrata | 97.74 | 2e-63 | 226 |
| LLPS-Brn-1992 | Brassica napus | 91.84 | 2e-51 | 192 |
| LLPS-Pot-2813 | Populus trichocarpa | 81.22 | 0.0 | 623 |
| LLPS-Viv-1766 | Vitis vinifera | 80.16 | 0.0 | 611 |
| LLPS-Cus-1200 | Cucumis sativus | 80.05 | 0.0 | 636 |
| LLPS-Prp-0966 | Prunus persica | 79.66 | 0.0 | 621 |
| LLPS-Gor-2214 | Gossypium raimondii | 77.78 | 0.0 | 622 |
| LLPS-Nia-0228 | Nicotiana attenuata | 75.79 | 5e-41 | 161 |
| LLPS-Dac-1551 | Daucus carota | 75.51 | 1e-41 | 163 |
| LLPS-Mua-2518 | Musa acuminata | 74.23 | 1e-35 | 144 |
| LLPS-Ori-2482 | Oryza indica | 73.61 | 6e-69 | 245 |
| LLPS-Phv-1485 | Phaseolus vulgaris | 73.51 | 0.0 | 578 |
| LLPS-Via-1099 | Vigna angularis | 72.49 | 0.0 | 557 |
| LLPS-Mae-2185 | Manihot esculenta | 72.21 | 0.0 | 566 |
| LLPS-Met-0575 | Medicago truncatula | 71.83 | 0.0 | 602 |
| LLPS-Amt-0640 | Amborella trichopoda | 71.78 | 0.0 | 560 |
| LLPS-Glm-0450 | Glycine max | 71.43 | 0.0 | 555 |
| LLPS-Hov-1586 | Hordeum vulgare | 71.39 | 0.0 | 543 |
| LLPS-Brd-1992 | Brachypodium distachyon | 71.13 | 0.0 | 543 |
| LLPS-Vir-0499 | Vigna radiata | 70.44 | 0.0 | 548 |
| LLPS-Hea-0566 | Helianthus annuus | 70.03 | 0.0 | 567 |
| LLPS-Coc-2075 | Corchorus capsularis | 70.02 | 0.0 | 561 |
| LLPS-Sei-1616 | Setaria italica | 69.9 | 0.0 | 543 |
| LLPS-Tra-0445 | Triticum aestivum | 69.72 | 0.0 | 545 |
| LLPS-Sob-1132 | Sorghum bicolor | 69.6 | 0.0 | 548 |
| LLPS-Php-0318 | Physcomitrella patens | 69.29 | 3e-179 | 527 |
| LLPS-Orgl-2224 | Oryza glumaepatula | 68.64 | 0.0 | 545 |
| LLPS-Orni-2354 | Oryza nivara | 68.64 | 0.0 | 545 |
| LLPS-Orr-2090 | Oryza rufipogon | 68.64 | 0.0 | 546 |
| LLPS-Ors-2078 | Oryza sativa | 68.64 | 0.0 | 545 |
| LLPS-Lep-1532 | Leersia perrieri | 68.56 | 0.0 | 550 |
| LLPS-Orbr-1449 | Oryza brachyantha | 68.4 | 0.0 | 540 |
| LLPS-Sem-1317 | Selaginella moellendorffii | 68.23 | 8e-166 | 491 |
| LLPS-Zem-1149 | Zea mays | 67.82 | 0.0 | 543 |
| LLPS-Orm-0543 | Oryza meridionalis | 67.65 | 2e-180 | 530 |
| LLPS-Orb-0952 | Oryza barthii | 66.17 | 2e-173 | 511 |
| LLPS-Orp-2244 | Oryza punctata | 66.17 | 2e-173 | 511 |
| LLPS-Tru-1577 | Triticum urartu | 65.79 | 8e-80 | 267 |
| LLPS-Sot-2050 | Solanum tuberosum | 65.31 | 3e-35 | 142 |
| LLPS-Sol-1718 | Solanum lycopersicum | 63.04 | 1e-147 | 439 |
| LLPS-Chc-0969 | Chondrus crispus | 61.67 | 1e-17 | 90.5 |
| LLPS-Cii-1571 | Ciona intestinalis | 60.61 | 6e-18 | 91.3 |
| LLPS-Cis-1545 | Ciona savignyi | 60.61 | 7e-18 | 91.3 |
| LLPS-Orn-0930 | Oreochromis niloticus | 60.61 | 6e-144 | 434 |
| LLPS-Leo-0865 | Lepisosteus oculatus | 60.33 | 3e-143 | 433 |
| LLPS-Gaa-3798 | Gasterosteus aculeatus | 60.06 | 5e-140 | 424 |
| LLPS-Aon-4816 | Aotus nancymaae | 59.63 | 3e-120 | 375 |
| LLPS-Osl-1299 | Ostreococcus lucimarinus | 59.57 | 2e-147 | 444 |
| LLPS-Bot-4318 | Bos taurus | 59.5 | 6e-141 | 427 |
| LLPS-Dio-2795 | Dipodomys ordii | 59.5 | 1e-141 | 429 |
| LLPS-Ran-3271 | Rattus norvegicus | 59.5 | 1e-141 | 429 |
| LLPS-Mup-3642 | Mustela putorius furo | 59.5 | 1e-141 | 429 |
| LLPS-Aim-1540 | Ailuropoda melanoleuca | 59.5 | 6e-142 | 429 |
| LLPS-Myl-2501 | Myotis lucifugus | 59.5 | 1e-141 | 429 |
| LLPS-Paa-3260 | Papio anubis | 59.5 | 2e-141 | 428 |
| LLPS-Mal-4583 | Mandrillus leucophaeus | 59.5 | 2e-141 | 428 |
| LLPS-Chs-3307 | Chlorocebus sabaeus | 59.5 | 2e-141 | 428 |
| LLPS-Mea-1373 | Mesocricetus auratus | 59.5 | 1e-141 | 428 |
| LLPS-Mum-3721 | Mus musculus | 59.5 | 4e-142 | 430 |
| LLPS-Cea-1118 | Cercocebus atys | 59.5 | 2e-141 | 428 |
| LLPS-Sah-2251 | Sarcophilus harrisii | 59.5 | 1e-141 | 429 |
| LLPS-Sus-1232 | Sus scrofa | 59.5 | 1e-141 | 429 |
| LLPS-Gog-4347 | Gorilla gorilla | 59.5 | 2e-141 | 428 |
| LLPS-Caj-1360 | Callithrix jacchus | 59.5 | 2e-141 | 428 |
| LLPS-Fud-2898 | Fukomys damarensis | 59.5 | 1e-141 | 429 |
| LLPS-Eqc-2195 | Equus caballus | 59.5 | 1e-141 | 429 |
| LLPS-Poa-1636 | Pongo abelii | 59.5 | 2e-141 | 428 |
| LLPS-Caf-1876 | Canis familiaris | 59.5 | 1e-141 | 429 |
| LLPS-Mam-2573 | Macaca mulatta | 59.5 | 4e-141 | 428 |
| LLPS-Gaga-4023 | Gallus gallus | 59.5 | 4e-142 | 430 |
| LLPS-Cas-3231 | Carlito syrichta | 59.5 | 1e-141 | 429 |
| LLPS-Ict-2870 | Ictidomys tridecemlineatus | 59.5 | 1e-141 | 429 |
| LLPS-Nol-3857 | Nomascus leucogenys | 59.5 | 2e-141 | 428 |
| LLPS-Lac-3233 | Latimeria chalumnae | 59.5 | 3e-142 | 430 |
| LLPS-Pat-0003 | Pan troglodytes | 59.5 | 7e-141 | 428 |
| LLPS-Meg-3273 | Meleagris gallopavo | 59.5 | 4e-142 | 430 |
| LLPS-Hos-3017 | Homo sapiens | 59.5 | 2e-141 | 428 |
| LLPS-Man-1903 | Macaca nemestrina | 59.5 | 1e-141 | 428 |
| LLPS-Rhb-0394 | Rhinopithecus bieti | 59.5 | 2e-141 | 428 |
| LLPS-Fia-1000 | Ficedula albicollis | 59.5 | 6e-142 | 429 |
| LLPS-Orc-2394 | Oryctolagus cuniculus | 59.5 | 1e-141 | 429 |
| LLPS-Asm-1596 | Astyanax mexicanus | 59.41 | 3e-145 | 438 |
| LLPS-Pes-2805 | Pelodiscus sinensis | 59.34 | 1e-139 | 424 |
| LLPS-Tar-1997 | Takifugu rubripes | 59.23 | 8e-141 | 426 |
| LLPS-Ova-0058 | Ovis aries | 59.23 | 7e-141 | 427 |
| LLPS-Ora-0605 | Ornithorhynchus anatinus | 59.23 | 8e-141 | 427 |
| LLPS-Cap-1039 | Cavia porcellus | 59.23 | 6e-141 | 427 |
| LLPS-Anc-3109 | Anolis carolinensis | 59.23 | 5e-141 | 427 |
| LLPS-Mod-3014 | Monodelphis domestica | 59.23 | 4e-141 | 427 |
| LLPS-Loa-2632 | Loxodonta africana | 59.23 | 8e-141 | 427 |
| LLPS-Tag-0245 | Taeniopygia guttata | 58.99 | 1e-136 | 415 |
| LLPS-Scm-2133 | Scophthalmus maximus | 58.99 | 5e-137 | 417 |
| LLPS-Fec-2291 | Felis catus | 58.95 | 2e-139 | 425 |
| LLPS-Urm-0506 | Ursus maritimus | 58.89 | 2e-137 | 419 |
| LLPS-Tut-2208 | Tursiops truncatus | 58.7 | 5e-118 | 368 |
| LLPS-Scf-2078 | Scleropages formosus | 58.68 | 4e-139 | 422 |
| LLPS-Anp-1649 | Anas platyrhynchos | 58.68 | 1e-139 | 424 |
| LLPS-Dar-3947 | Danio rerio | 58.61 | 5e-137 | 417 |
| LLPS-Ten-1319 | Tetraodon nigroviridis | 58.4 | 1e-137 | 418 |
| LLPS-Icp-2606 | Ictalurus punctatus | 58.29 | 6e-137 | 417 |
| LLPS-Chr-0388 | Chlamydomonas reinhardtii | 58.04 | 6e-135 | 416 |
| LLPS-Orl-0937 | Oryzias latipes | 57.94 | 3e-141 | 427 |
| LLPS-Xim-1910 | Xiphophorus maculatus | 57.82 | 1e-138 | 421 |
| LLPS-Otg-1839 | Otolemur garnettii | 57.3 | 6e-133 | 406 |
| LLPS-Maf-4307 | Macaca fascicularis | 57.02 | 1e-128 | 396 |
| LLPS-Xet-0334 | Xenopus tropicalis | 56.91 | 6e-140 | 425 |
| LLPS-Pof-2959 | Poecilia formosa | 56.73 | 2e-138 | 421 |
| LLPS-Pap-1645 | Pan paniscus | 56.73 | 3e-138 | 422 |
| LLPS-Drm-1434 | Drosophila melanogaster | 55.97 | 9e-133 | 412 |
| LLPS-Cym-0698 | Cyanidioschyzon merolae | 52.24 | 8e-16 | 84.7 |
| LLPS-Gas-1340 | Galdieria sulphuraria | 52.19 | 4e-131 | 401 |
| LLPS-Abg-0364 | Absidia glauca | 47.26 | 1e-107 | 343 |
| LLPS-Yal-1136 | Yarrowia lipolytica | 44.58 | 2e-12 | 74.3 |
| LLPS-Spr-0792 | Sporisorium reilianum | 43.81 | 6e-23 | 108 |
| LLPS-Usm-0915 | Ustilago maydis | 42.86 | 4e-22 | 105 |
| LLPS-Tum-1611 | Tuber melanosporum | 39.05 | 6e-29 | 122 |
| LLPS-Miv-1528 | Microbotryum violaceum | 38.27 | 2e-07 | 58.9 |
| LLPS-Sac-0045 | Saccharomyces cerevisiae | 24.92 | 5e-28 | 122 |