LLPS-Art-1824
AL7
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
| Nucleolus | "...Comparative analysis revealed that 562 proteins were consistently identified in both experimental data sets." | 3 weeks-old Arabidopsis thaliana plants | 29104584 |
▼ FUNCTION
| Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT1G14510.1 | AT1G14510.1 |
| UniProt | Q8LA16, ALFL7_ARATH, Q9M9R2, Q9MA31 | |
| GeneBank | BT006199, AC012188, CP002684, AC010657, AY088087, AK228067 | AAP12848.1, AAF43952.1, AAM65633.1, AAF63181.1, AEE29173.1, BAF00027.1 |
| RefSeq | NM_101318.4 | NP_172903.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEGIQHPIPR TVEEVFSDFR GRRAGLIKAL STDVQKFYHQ CDPEKENLCL YGLPNETWEV 60 61 NLPVEEVPPE LPEPALGINF ARDGMQEKDW ISLVAVHSDS WLISVAFYFG ARFGFGKNER 120 121 KRLFQMINDL PTIFEVVTGN AKQSKDQSAN HNSSRSKSSG GKPRHSESHT KASKMSPPPR 180 181 KEDESGDEDE DDEQGAVCGA CGDNYGGDEF WICCDACEKW FHGKCVKITP AKAEHIKHYK 240 241 CPSCTTSKKM KA 252 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAAGGAA TTCAGCATCC TATACCTCGC ACTGTCGAAG AGGTTTTTAG CGACTTTCGT 60 61 GGTCGTAGAG CTGGTCTCAT CAAGGCTCTC TCTACTGATG TACAGAAGTT TTACCATCAG 120 121 TGTGACCCTG AGAAGGAAAA CTTGTGTCTT TATGGACTTC CAAATGAGAC ATGGGAGGTT 180 181 AATCTTCCCG TTGAGGAGGT CCCTCCTGAG CTTCCTGAAC CAGCGTTAGG CATCAATTTC 240 241 GCAAGGGACG GAATGCAAGA AAAAGACTGG ATTTCTTTGG TTGCAGTTCA CAGTGATTCA 300 301 TGGCTTATCT CTGTTGCATT TTACTTTGGT GCACGTTTCG GATTTGGCAA GAATGAGAGG 360 361 AAGAGGCTCT TCCAGATGAT AAATGATCTC CCAACCATTT TCGAGGTTGT AACTGGCAAT 420 421 GCAAAGCAAT CCAAGGATCA ATCTGCTAAC CACAACAGTA GCAGAAGCAA ATCTAGTGGT 480 481 GGCAAGCCTC GTCATTCTGA ATCTCACACT AAGGCTTCAA AGATGTCCCC TCCACCAAGA 540 541 AAAGAAGATG AGAGCGGAGA TGAGGATGAA GATGACGAGC AAGGTGCTGT TTGTGGTGCG 600 601 TGTGGCGACA ACTATGGAGG AGATGAGTTC TGGATATGTT GTGATGCTTG CGAGAAATGG 660 661 TTCCATGGGA AATGCGTGAA GATCACACCA GCAAAGGCTG AGCATATCAA ACATTACAAA 720 721 TGCCCAAGTT GCACTACCAG CAAGAAAATG AAAGCCTGA 759 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nucleus | |
Molecular Function | Metal ion binding | |
Molecular Function | Methylated histone binding | |
Biological Process | Chromatin organization | |
Biological Process | Regulation of transcription, DNA-templated |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Structure | ||||
| PDB | ||||
| Localization | ||||
| COMPARTMENTS | NLSdb | |||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-1322 | Arabidopsis lyrata | 96.83 | 5e-141 | 403 |
| LLPS-Brn-3205 | Brassica napus | 88.89 | 2e-129 | 374 |
| LLPS-Brr-1751 | Brassica rapa | 88.89 | 2e-129 | 374 |
| LLPS-Bro-2588 | Brassica oleracea | 88.49 | 7e-128 | 370 |
| LLPS-Gor-1882 | Gossypium raimondii | 80.8 | 6e-118 | 345 |
| LLPS-Glm-0565 | Glycine max | 80.32 | 1e-121 | 354 |
| LLPS-Pot-1610 | Populus trichocarpa | 78.63 | 4e-117 | 342 |
| LLPS-Nia-0271 | Nicotiana attenuata | 76.21 | 1e-108 | 321 |
| LLPS-Sol-2023 | Solanum lycopersicum | 76.11 | 1e-107 | 318 |
| LLPS-Hea-1548 | Helianthus annuus | 75.81 | 2e-108 | 322 |
| LLPS-Tra-2546 | Triticum aestivum | 72.84 | 6e-103 | 306 |
| LLPS-Dac-0345 | Daucus carota | 71.83 | 2e-106 | 315 |
| LLPS-Lep-0872 | Leersia perrieri | 71.02 | 5e-103 | 307 |
| LLPS-Mua-2255 | Musa acuminata | 69.55 | 1e-95 | 288 |
| LLPS-Via-0771 | Vigna angularis | 69.55 | 2e-97 | 293 |
| LLPS-Mae-2644 | Manihot esculenta | 68.44 | 4e-98 | 294 |
| LLPS-Orp-1679 | Oryza punctata | 68.31 | 3e-94 | 285 |
| LLPS-Orb-0313 | Oryza barthii | 68.03 | 2e-92 | 280 |
| LLPS-Ori-0614 | Oryza indica | 68.03 | 2e-92 | 280 |
| LLPS-Orni-1801 | Oryza nivara | 68.03 | 2e-92 | 280 |
| LLPS-Orgl-1457 | Oryza glumaepatula | 68.03 | 2e-92 | 280 |
| LLPS-Ors-2211 | Oryza sativa | 68.03 | 2e-92 | 280 |
| LLPS-Orr-2122 | Oryza rufipogon | 68.03 | 2e-92 | 280 |
| LLPS-Org-0935 | Oryza glaberrima | 68.03 | 2e-92 | 280 |
| LLPS-Sob-0817 | Sorghum bicolor | 67.6 | 1e-95 | 288 |
| LLPS-Sei-1071 | Setaria italica | 65.83 | 2e-92 | 280 |
| LLPS-Orbr-1253 | Oryza brachyantha | 65.77 | 2e-93 | 286 |
| LLPS-Hov-2213 | Hordeum vulgare | 64.11 | 4e-93 | 282 |
| LLPS-Php-0163 | Physcomitrella patens | 62.0 | 3e-83 | 256 |
| LLPS-Cis-1611 | Ciona savignyi | 54.05 | 2e-06 | 52.4 |
| LLPS-Tar-1726 | Takifugu rubripes | 53.49 | 8e-07 | 53.5 |
| LLPS-Sem-0949 | Selaginella moellendorffii | 51.67 | 1e-57 | 190 |
| LLPS-Scf-3457 | Scleropages formosus | 51.16 | 4e-06 | 52.0 |
| LLPS-Leo-1929 | Lepisosteus oculatus | 50.0 | 5e-06 | 51.6 |
| LLPS-Anp-2283 | Anas platyrhynchos | 47.62 | 9e-06 | 50.4 |
| LLPS-Ran-1548 | Rattus norvegicus | 43.75 | 2e-07 | 55.8 |
| LLPS-Cii-1864 | Ciona intestinalis | 43.18 | 8e-07 | 53.9 |
| LLPS-Cae-1449 | Caenorhabditis elegans | 42.31 | 2e-07 | 55.5 |
| LLPS-Orl-2423 | Oryzias latipes | 41.67 | 7e-08 | 57.0 |
| LLPS-Cea-2494 | Cercocebus atys | 41.67 | 4e-07 | 54.7 |
| LLPS-Aon-2973 | Aotus nancymaae | 41.67 | 2e-06 | 52.4 |
| LLPS-Maf-3921 | Macaca fascicularis | 41.67 | 4e-07 | 54.7 |
| LLPS-Chs-1778 | Chlorocebus sabaeus | 41.67 | 4e-07 | 54.7 |
| LLPS-Fud-2080 | Fukomys damarensis | 41.67 | 4e-07 | 54.7 |
| LLPS-Caj-0107 | Callithrix jacchus | 41.67 | 4e-07 | 54.7 |
| LLPS-Gog-4806 | Gorilla gorilla | 41.67 | 4e-07 | 54.7 |
| LLPS-Dio-2883 | Dipodomys ordii | 41.67 | 5e-07 | 54.7 |
| LLPS-Gaa-2468 | Gasterosteus aculeatus | 41.67 | 1e-07 | 56.6 |
| LLPS-Bot-3822 | Bos taurus | 41.67 | 4e-07 | 54.7 |
| LLPS-Xim-2478 | Xiphophorus maculatus | 41.67 | 8e-08 | 57.0 |
| LLPS-Paa-4198 | Papio anubis | 41.67 | 4e-07 | 54.7 |
| LLPS-Mup-1683 | Mustela putorius furo | 41.67 | 4e-07 | 54.7 |
| LLPS-Ova-4216 | Ovis aries | 41.67 | 5e-07 | 54.7 |
| LLPS-Myl-2382 | Myotis lucifugus | 41.67 | 4e-07 | 55.1 |
| LLPS-Loa-2560 | Loxodonta africana | 41.67 | 4e-07 | 54.7 |
| LLPS-Dar-1212 | Danio rerio | 41.67 | 9e-08 | 56.6 |
| LLPS-Hos-4208 | Homo sapiens | 41.67 | 4e-07 | 54.7 |
| LLPS-Pat-3858 | Pan troglodytes | 41.67 | 4e-07 | 54.7 |
| LLPS-Pof-0832 | Poecilia formosa | 41.67 | 8e-08 | 57.0 |
| LLPS-Pap-0289 | Pan paniscus | 41.67 | 4e-07 | 54.7 |
| LLPS-Scm-3426 | Scophthalmus maximus | 41.67 | 2e-07 | 55.8 |
| LLPS-Fec-3287 | Felis catus | 41.67 | 3e-07 | 55.1 |
| LLPS-Orc-1345 | Oryctolagus cuniculus | 41.67 | 5e-07 | 54.7 |
| LLPS-Orn-2819 | Oreochromis niloticus | 41.67 | 7e-08 | 57.0 |
| LLPS-Rhb-4800 | Rhinopithecus bieti | 41.67 | 4e-07 | 54.7 |
| LLPS-Mam-4132 | Macaca mulatta | 41.67 | 4e-07 | 54.7 |
| LLPS-Ten-2610 | Tetraodon nigroviridis | 41.67 | 1e-07 | 56.2 |
| LLPS-Caf-2246 | Canis familiaris | 41.67 | 4e-07 | 54.7 |
| LLPS-Cap-2952 | Cavia porcellus | 41.67 | 4e-07 | 54.7 |
| LLPS-Eqc-1407 | Equus caballus | 41.67 | 3e-07 | 55.1 |
| LLPS-Anc-3879 | Anolis carolinensis | 41.67 | 3e-08 | 58.2 |
| LLPS-Nol-4413 | Nomascus leucogenys | 41.67 | 4e-07 | 54.7 |
| LLPS-Ict-2057 | Ictidomys tridecemlineatus | 41.67 | 5e-07 | 54.7 |
| LLPS-Asm-2417 | Astyanax mexicanus | 40.82 | 9e-08 | 56.6 |
| LLPS-Sah-1032 | Sarcophilus harrisii | 39.58 | 1e-06 | 53.1 |
| LLPS-Mum-1679 | Mus musculus | 39.58 | 1e-06 | 53.1 |
| LLPS-Ora-1768 | Ornithorhynchus anatinus | 39.58 | 1e-06 | 53.5 |
| LLPS-Icp-2446 | Ictalurus punctatus | 39.58 | 1e-06 | 53.5 |
| LLPS-Meg-2896 | Meleagris gallopavo | 39.58 | 1e-06 | 53.1 |
| LLPS-Mod-3728 | Monodelphis domestica | 39.58 | 1e-06 | 53.5 |
| LLPS-Fia-2923 | Ficedula albicollis | 39.58 | 2e-06 | 53.1 |