LLPS-Art-1458
UGD4

▼ OVERVIEW

Status: Reviewed
Protein Name: UDP-glucose 6-dehydrogenase 4
Gene Name: UGD4, UGD1, At5g39320, K3K3.170
Ensembl Gene: AT5G39320
Ensembl Protein: AT5G39320.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVKICCIGAG  YVGGPTMAVI  ALKCPDIEVA  VVDISVPRIN  AWNSDQLPIY  EPGLDDIVKQ  60
61    CRGKNLFFST  DVEKHVREAD  IVFVSVNTPT  KTTGLGAGKA  ADLTYWESAA  RMIADVSVSD  120
121   KIVVEKSTVP  VKTAEAIEKI  LMHNSKGIKF  QILSNPEFLA  EGTAIADLFN  PDRVLIGGRE  180
181   TPEGFKAVQT  LKEVYANWVP  EGQIITTNLW  SAELSKLAAN  AFLAQRISSV  NAMSALCEST  240
241   GADVTQVSYA  VGTDSRIGSK  FLNASVGFGG  SCFQKDILNL  VYICQCNGLP  EVAEYWKQVI  300
301   KINDYQKNRF  VNRIVSSMFN  TVSNKKVAIL  GFAFKKDTGD  TRETPAIDVC  KGLLGDKAQI  360
361   SIYDPQVTEE  QIQRDLSMKK  FDWDHPLHLQ  PMSPTTVKQV  SVTWDAYEAT  KDAHAVCVLT  420
421   EWDEFKSLDY  QKIFDNMQKP  AFIFDGRNIM  NVNKLREIGF  IVYSIGKPLD  PWLKDMPAFV  480
Nucleotide CDS Sequence (FASTA)
1     ATGGTGAAGA  TCTGTTGTAT  TGGAGCTGGA  TATGTAGGAG  GACCAACAAT  GGCAGTGATT  60
61    GCATTGAAAT  GTCCAGATAT  TGAAGTGGCA  GTTGTTGATA  TCTCTGTTCC  TAGAATCAAC  120
121   GCTTGGAACA  GTGATCAGCT  TCCGATTTAC  GAGCCAGGTC  TTGACGATAT  CGTTAAGCAA  180
181   TGCAGAGGAA  AGAATCTTTT  CTTCAGTACT  GATGTGGAGA  AACATGTTAG  AGAAGCTGAT  240
241   ATTGTCTTTG  TCTCTGTTAA  CACACCGACT  AAAACGACTG  GTCTTGGAGC  TGGGAAAGCT  300
301   GCTGATCTCA  CTTATTGGGA  GAGTGCTGCT  CGTATGATCG  CGGATGTATC  GGTTTCTGAC  360
361   AAGATTGTTG  TTGAGAAATC  GACTGTTCCG  GTGAAGACAG  CTGAAGCTAT  TGAGAAGATT  420
421   TTGATGCATA  ACAGTAAAGG  AATCAAGTTT  CAGATTCTTT  CGAATCCGGA  GTTTCTTGCT  480
481   GAAGGAACTG  CTATCGCTGA  TCTTTTTAAC  CCTGACCGTG  TTTTGATCGG  AGGGCGAGAA  540
541   ACACCTGAAG  GATTCAAAGC  TGTTCAGACA  CTTAAAGAGG  TTTATGCTAA  TTGGGTTCCT  600
601   GAAGGTCAGA  TCATCACAAC  TAATCTCTGG  TCTGCTGAGC  TTTCTAAGTT  AGCTGCAAAT  660
661   GCTTTCTTGG  CTCAGAGGAT  TTCATCAGTC  AATGCCATGT  CTGCACTTTG  TGAATCCACT  720
721   GGTGCTGATG  TTACTCAAGT  GTCTTACGCT  GTTGGTACTG  ATTCAAGAAT  CGGTTCCAAA  780
781   TTCTTGAACG  CTAGTGTTGG  ATTCGGAGGT  TCTTGTTTCC  AGAAGGACAT  TCTGAATCTC  840
841   GTCTACATCT  GTCAATGCAA  CGGACTTCCA  GAAGTGGCGG  AATACTGGAA  ACAAGTGATC  900
901   AAGATCAACG  ATTACCAAAA  GAACCGGTTC  GTGAACAGAA  TCGTGTCCTC  TATGTTCAAC  960
961   ACTGTCTCCA  ACAAGAAGGT  TGCGATTCTT  GGATTCGCAT  TCAAGAAAGA  CACTGGTGAC  1020
1021  ACAAGGGAAA  CACCTGCCAT  TGATGTGTGT  AAAGGTCTAT  TAGGAGACAA  AGCACAGATC  1080
1081  AGTATCTATG  ATCCTCAAGT  CACAGAGGAA  CAGATTCAGA  GAGATCTCTC  GATGAAAAAG  1140
1141  TTCGACTGGG  ACCATCCTCT  TCACTTGCAG  CCAATGAGTC  CAACCACAGT  GAAACAAGTG  1200
1201  AGTGTGACTT  GGGACGCATA  TGAAGCTACA  AAAGACGCAC  ACGCGGTTTG  CGTTTTGACT  1260
1261  GAGTGGGACG  AGTTTAAGTC  GTTAGATTAC  CAGAAGATCT  TCGACAACAT  GCAGAAACCG  1320
1321  GCTTTTATCT  TCGACGGAAG  AAACATTATG  AATGTTAACA  AGTTAAGAGA  GATTGGTTTC  1380
1381  ATTGTTTACT  CCATTGGTAA  GCCACTTGAC  CCATGGCTCA  AGGACATGCC  TGCCTTTGTC  1440
1441  TAA  1443

▼ KEYWORD

ID
Family
Complete proteome
NAD
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apoplast
Cellular Component
Cytosol
Cellular Component
Nucleus
Molecular Function
NAD binding
Molecular Function
UDP-glucose 6-dehydrogenase activity
Biological Process
Glycosaminoglycan biosynthetic process
Biological Process
UDP-glucuronate biosynthetic process

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Function
CGDBPIRSF
Localization
COMPARTMENTS
Expression
ArrayExpress

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0181Arabidopsis lyrata97.920.0 973
LLPS-Brr-1488Brassica rapa97.710.0 974
LLPS-Brn-1690Brassica napus97.290.0 969
LLPS-Bro-1137Brassica oleracea97.290.0 969
LLPS-Thc-1702Theobroma cacao91.210.0 922
LLPS-Coc-0779Corchorus capsularis91.210.0 919
LLPS-Nia-2354Nicotiana attenuata91.020.0 912
LLPS-Gor-2383Gossypium raimondii91.00.0 918
LLPS-Dac-1971Daucus carota90.380.0 909
LLPS-Met-1399Medicago truncatula89.960.0 909
LLPS-Sot-0429Solanum tuberosum89.770.0 899
LLPS-Sol-1722Solanum lycopersicum89.750.0 900
LLPS-Glm-0676Glycine max89.560.0 904
LLPS-Vir-0866Vigna radiata89.540.0 902
LLPS-Via-2054Vigna angularis89.540.0 900
LLPS-Phv-2562Phaseolus vulgaris89.540.0 899
LLPS-Mae-0529Manihot esculenta89.330.0 904
LLPS-Cus-1309Cucumis sativus88.910.0 904
LLPS-Brd-2122Brachypodium distachyon88.490.0 890
LLPS-Sei-0613Setaria italica88.280.0 890
LLPS-Hov-0042Hordeum vulgare88.080.0 889
LLPS-Tra-2762Triticum aestivum88.080.0 887
LLPS-Zem-1692Zea mays88.080.0 890
LLPS-Pot-0486Populus trichocarpa87.890.0 885
LLPS-Orr-1094Oryza rufipogon87.660.0 886
LLPS-Orp-1931Oryza punctata87.450.0 885
LLPS-Orb-0226Oryza barthii87.270.0 885
LLPS-Ori-1458Oryza indica87.240.0 883
LLPS-Orbr-1664Oryza brachyantha87.240.0 883
LLPS-Ors-2377Oryza sativa87.240.0 883
LLPS-Org-1056Oryza glaberrima87.240.0 881
LLPS-Tru-2054Triticum urartu87.230.0 857
LLPS-Prp-1304Prunus persica87.060.0 883
LLPS-Orni-0380Oryza nivara87.030.0 880
LLPS-Lep-0903Leersia perrieri86.820.0 881
LLPS-Sob-1720Sorghum bicolor86.820.0 884
LLPS-Viv-1781Vitis vinifera85.770.0 882
LLPS-Php-0683Physcomitrella patens85.290.0 865
LLPS-Orgl-0253Oryza glumaepatula83.090.0 857
LLPS-Orm-0374Oryza meridionalis81.250.0 839
LLPS-Amt-2138Amborella trichopoda73.681e-158 459
LLPS-Mua-2322Musa acuminata73.010.0 703
LLPS-Lac-3747Latimeria chalumnae69.391e-1480.1
LLPS-Drm-1445Drosophila melanogaster63.680.0 613
LLPS-Abg-0902Absidia glauca62.390.0 570
LLPS-Sah-3979Sarcophilus harrisii62.070.0 585
LLPS-Mup-2986Mustela putorius furo61.750.0 591
LLPS-Ova-3673Ovis aries61.750.0 590
LLPS-Pes-3480Pelodiscus sinensis61.750.0 590
LLPS-Fec-4477Felis catus61.750.0 590
LLPS-Fud-2203Fukomys damarensis61.540.0 585
LLPS-Gog-1770Gorilla gorilla61.540.0 589
LLPS-Ora-0323Ornithorhynchus anatinus61.540.0 589
LLPS-Chs-4513Chlorocebus sabaeus61.540.0 589
LLPS-Ran-0917Rattus norvegicus61.540.0 590
LLPS-Bot-0314Bos taurus61.540.0 589
LLPS-Loa-2669Loxodonta africana61.540.0 590
LLPS-Hos-3978Homo sapiens61.540.0 589
LLPS-Pat-3876Pan troglodytes61.540.0 589
LLPS-Urm-2493Ursus maritimus61.540.0 589
LLPS-Pap-3754Pan paniscus61.540.0 588
LLPS-Mod-1166Monodelphis domestica61.540.0 589
LLPS-Nol-0407Nomascus leucogenys61.540.0 589
LLPS-Ict-3235Ictidomys tridecemlineatus61.540.0 588
LLPS-Cas-0921Carlito syrichta61.540.0 589
LLPS-Poa-3037Pongo abelii61.540.0 589
LLPS-Caf-1831Canis familiaris61.540.0 589
LLPS-Eqc-4543Equus caballus61.540.0 588
LLPS-Crn-0973Cryptococcus neoformans61.510.0 593
LLPS-Man-2941Macaca nemestrina61.350.0 552
LLPS-Caj-3488Callithrix jacchus61.320.0 587
LLPS-Cea-2208Cercocebus atys61.320.0 586
LLPS-Mal-3174Mandrillus leucophaeus61.320.0 586
LLPS-Paa-2682Papio anubis61.320.0 588
LLPS-Rhb-3652Rhinopithecus bieti61.320.0 586
LLPS-Myl-1833Myotis lucifugus61.190.0 581
LLPS-Leo-2394Lepisosteus oculatus60.980.0 601
LLPS-Orc-4325Oryctolagus cuniculus59.870.0 564
LLPS-Yal-0576Yarrowia lipolytica59.580.0 570
LLPS-Pug-0427Puccinia graminis58.970.0 560
LLPS-Tut-1576Tursiops truncatus58.80.0 553
LLPS-Otg-1217Otolemur garnettii58.550.0 550
LLPS-Put-1314Puccinia triticina58.120.0 552
LLPS-Fus-1274Fusarium solani50.334e-151 451
LLPS-Fuv-1111Fusarium verticillioides48.588e-148 443
LLPS-Fuo-1387Fusarium oxysporum48.583e-148 444
LLPS-Aso-0705Aspergillus oryzae46.513e-148 440
LLPS-Cogr-1475Colletotrichum graminicola45.251e-130 401
LLPS-Nec-0011Neurospora crassa45.179e-136 414
LLPS-Ast-1309Aspergillus terreus42.525e-138 414
LLPS-Asni-0170Aspergillus niger38.721e-103 324
LLPS-Cym-0644Cyanidioschyzon merolae30.322e-1994.7
LLPS-Pyt-0378Pyrenophora teres24.679e-0858.5
LLPS-Pytr-1508Pyrenophora triticirepentis23.596e-0859.3