LLPS-Art-1281
FTSH1

▼ OVERVIEW

Status: Reviewed
Protein Name: ATP-dependent zinc metalloprotease FTSH 1, chloroplastic
Gene Name: FTSH1, AAA, FTSH, At1g50250, F14I3.14
Ensembl Gene: AT1G50250
Ensembl Protein: AT1G50250.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...Comparative analysis revealed that 562 proteins were consistently identified in both experimental data sets."
3 weeks-old Arabidopsis thaliana plants29104584

▼ FUNCTION

Part of a complex that function as an ATP-dependent zinc metallopeptidase. Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MASNSLLRSS  SNFFLGSHII  ISSPTPKTTR  KPSFPFSFVS  RAKYQITRSS  QDENSPNGKP  60
61    NSPFSSQVAL  AAILLSSISS  SPLALAVVDE  PASPSVVIES  QAVKPSTPSP  LFIQNEILKA  120
121   PSPKSSDLPE  GSQWRYSEFL  NAVKKGKVER  VRFSKDGSVV  QLTAVDNRRA  SVIVPNDPDL  180
181   IDILAMNGVD  ISVSEGESSG  NDLFTVIGNL  IFPLLAFGGL  FLLFRRAQGG  PGGGPGGLGG  240
241   PMDFGRSKSK  FQEVPETGVS  FADVAGADQA  KLELQEVVDF  LKNPDKYTAL  GAKIPKGCLL  300
301   VGPPGTGKTL  LARAVAGEAG  VPFFSCAASE  FVELFVGVGA  SRVRDLFEKA  KSKAPCIVFI  360
361   DEIDAVGRQR  GAGMGGGNDE  REQTINQLLT  EMDGFSGNSG  VIVLAATNRP  DVLDSALLRP  420
421   GRFDRQVTVD  RPDVAGRVKI  LQVHSRGKAL  GKDVDFDKVA  RRTPGFTGAD  LQNLMNEAAI  480
481   LAARRELKEI  SKDEISDALE  RIIAGPEKKN  AVVSEEKKRL  VAYHEAGHAL  VGALMPEYDP  540
541   VAKISIIPRG  QAGGLTFFAP  SEERLESGLY  SRSYLENQMA  VALGGRVAEE  VIFGDENVTT  600
601   GASNDFMQVS  RVARQMIERF  GFSKKIGQVA  VGGPGGNPFM  GQQMSSQKDY  SMATADIVDA  660
661   EVRELVEKAY  KRATEIITTH  IDILHKLAQL  LIEKETVDGE  EFMSLFIDGQ  AELYIS  716
Nucleotide CDS Sequence (FASTA)
1     ATGGCTTCTA  ACTCATTACT  ACGTTCTTCT  TCAAATTTCT  TCTTAGGATC  CCATATCATA  60
61    ATCTCATCTC  CCACCCCTAA  AACCACCAGA  AAACCCTCTT  TCCCTTTCTC  CTTCGTCTCC  120
121   CGTGCTAAAT  ACCAAATCAC  TCGATCGTCT  CAAGACGAAA  ATTCGCCAAA  TGGTAAACCC  180
181   AATTCGCCAT  TCTCGTCGCA  AGTAGCCTTA  GCAGCTATTC  TACTATCTTC  AATTTCATCT  240
241   TCGCCGCTAG  CTTTAGCTGT  AGTGGACGAA  CCAGCTTCTC  CGTCTGTCGT  TATAGAATCT  300
301   CAAGCTGTGA  AGCCATCGAC  GCCATCGCCA  TTGTTCATTC  AGAACGAGAT  ACTTAAGGCT  360
361   CCTAGTCCTA  AATCATCGGA  TCTCCCAGAA  GGATCACAGT  GGCGATACAG  CGAGTTTCTT  420
421   AACGCTGTGA  AGAAAGGGAA  AGTCGAGAGA  GTTAGATTCA  GCAAAGATGG  TTCTGTTGTT  480
481   CAGCTTACTG  CCGTCGACAA  TCGCCGTGCT  TCAGTCATCG  TCCCTAACGA  CCCTGACCTT  540
541   ATTGATATCT  TGGCTATGAA  CGGAGTTGAT  ATATCCGTCT  CTGAAGGAGA  ATCCTCAGGC  600
601   AATGACTTGT  TCACTGTCAT  TGGAAACTTG  ATTTTCCCGC  TTTTGGCCTT  TGGTGGACTC  660
661   TTCTTGCTTT  TCAGGCGAGC  TCAGGGAGGC  CCTGGTGGTG  GTCCTGGTGG  CTTGGGTGGT  720
721   CCTATGGATT  TCGGACGTTC  TAAATCCAAG  TTCCAGGAAG  TGCCTGAGAC  TGGTGTATCA  780
781   TTTGCAGATG  TTGCTGGGGC  TGATCAAGCT  AAGTTGGAGT  TACAGGAAGT  TGTGGATTTC  840
841   TTGAAGAATC  CTGATAAGTA  CACAGCCTTG  GGTGCTAAGA  TTCCTAAAGG  GTGTTTGCTT  900
901   GTTGGACCGC  CTGGTACGGG  TAAGACACTC  CTGGCTAGGG  CGGTGGCTGG  GGAAGCTGGA  960
961   GTGCCGTTCT  TCTCTTGCGC  GGCCTCGGAG  TTCGTAGAGC  TTTTTGTGGG  TGTGGGTGCA  1020
1021  TCGAGAGTTA  GGGATTTGTT  CGAGAAGGCT  AAGTCTAAAG  CCCCTTGTAT  TGTATTCATT  1080
1081  GATGAGATTG  ACGCTGTGGG  TAGGCAGAGA  GGAGCTGGGA  TGGGAGGAGG  AAATGATGAG  1140
1141  AGAGAACAGA  CTATTAATCA  GCTGTTGACA  GAGATGGATG  GATTTTCTGG  CAACTCTGGT  1200
1201  GTGATAGTTT  TGGCAGCTAC  GAATAGGCCG  GACGTTCTTG  ATTCGGCTTT  GTTGAGGCCT  1260
1261  GGAAGGTTTG  ATCGACAGGT  CACGGTGGAT  AGGCCTGATG  TGGCTGGCAG  AGTCAAGATT  1320
1321  CTTCAGGTTC  ATTCTAGGGG  GAAGGCACTC  GGTAAAGATG  TGGACTTTGA  CAAGGTTGCC  1380
1381  AGAAGGACCC  CTGGTTTCAC  GGGTGCTGAC  TTACAAAACC  TGATGAATGA  AGCGGCGATT  1440
1441  CTTGCGGCTA  GGCGTGAGCT  TAAGGAAATA  AGCAAGGATG  AAATCTCTGA  TGCTCTTGAG  1500
1501  AGGATCATTG  CTGGACCTGA  GAAGAAGAAT  GCAGTTGTCT  CTGAAGAGAA  GAAGAGACTT  1560
1561  GTTGCATACC  ATGAGGCTGG  TCATGCTCTA  GTGGGTGCTC  TTATGCCAGA  ATATGATCCG  1620
1621  GTTGCAAAGA  TTTCTATCAT  TCCTCGTGGC  CAAGCTGGTG  GGCTCACTTT  TTTTGCTCCA  1680
1681  AGCGAAGAAA  GACTTGAGTC  TGGATTGTAC  AGTAGGAGCT  ACCTTGAGAA  TCAAATGGCT  1740
1741  GTTGCACTTG  GCGGAAGGGT  TGCAGAGGAG  GTGATCTTTG  GGGATGAGAA  TGTGACGACT  1800
1801  GGAGCATCAA  ATGATTTCAT  GCAGGTGTCT  CGTGTGGCAC  GTCAAATGAT  TGAGAGATTT  1860
1861  GGGTTCAGCA  AAAAGATTGG  ACAAGTTGCT  GTTGGTGGCC  CTGGTGGAAA  TCCCTTCATG  1920
1921  GGTCAACAAA  TGTCATCACA  GAAAGATTAC  TCAATGGCAA  CTGCGGATAT  TGTAGATGCT  1980
1981  GAGGTGCGAG  AGTTAGTTGA  GAAGGCATAC  AAGAGAGCAA  CGGAGATCAT  AACAACTCAT  2040
2041  ATTGATATCC  TACACAAGCT  TGCACAGCTC  CTGATCGAGA  AAGAAACTGT  TGACGGTGAA  2100
2101  GAGTTCATGA  GTCTCTTTAT  TGACGGCCAA  GCTGAGTTGT  ATATTTCTTG  A  2151

▼ KEYWORD

ID
Family
ATP-binding
Chloroplast
Complete proteome
Developmental protein
Hydrolase
Membrane
Metal-binding
Metalloprotease
Nucleotide-binding
Plastid
Protease
Reference proteome
Thylakoid
Transit peptide
Transmembrane
Transmembrane helix
Ubl conjugation
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Chloroplast envelope
Cellular Component
Chloroplast thylakoid
Cellular Component
Chloroplast thylakoid membrane
Cellular Component
Integral component of membrane
Cellular Component
Membrane
Cellular Component
Thylakoid lumen
Molecular Function
ATP binding
Molecular Function
ATP-dependent peptidase activity
Molecular Function
Metal ion binding
Molecular Function
Metalloendopeptidase activity
Biological Process
Multicellular organism development
Biological Process
Photoinhibition
Biological Process
Photosystem II repair
Biological Process
Proteolysis
Biological Process
PSII associated light-harvesting complex II catabolic process
Biological Process
Thylakoid membrane organization

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0114Arabidopsis lyrata98.150.01258
LLPS-Orgl-1825Oryza glumaepatula95.370.0 909
LLPS-Tru-0693Triticum urartu93.330.0 691
LLPS-Orr-1332Oryza rufipogon88.870.01043
LLPS-Orni-0936Oryza nivara87.840.01045
LLPS-Ors-1220Oryza sativa87.680.01044
LLPS-Orbr-2099Oryza brachyantha87.360.01044
LLPS-Ori-2265Oryza indica78.320.0 913
LLPS-Sob-2425Sorghum bicolor54.173e-178 532
LLPS-Phv-0704Phaseolus vulgaris53.832e-175 526
LLPS-Lep-1296Leersia perrieri53.837e-176 530
LLPS-Chc-0575Chondrus crispus53.810.0 553
LLPS-Tra-1912Triticum aestivum53.772e-174 522
LLPS-Hov-2051Hordeum vulgare53.753e-173 519
LLPS-Orp-2112Oryza punctata53.664e-175 527
LLPS-Orm-0559Oryza meridionalis53.662e-176 528
LLPS-Orb-2182Oryza barthii53.661e-176 528
LLPS-Vir-1266Vigna radiata53.665e-175 525
LLPS-Php-0842Physcomitrella patens53.491e-174 524
LLPS-Sei-1581Setaria italica53.432e-177 530
LLPS-Pot-0032Populus trichocarpa53.328e-174 522
LLPS-Dac-1957Daucus carota53.258e-175 524
LLPS-Thc-2017Theobroma cacao53.257e-175 524
LLPS-Gor-1794Gossypium raimondii53.085e-176 528
LLPS-Hea-1730Helianthus annuus53.085e-174 523
LLPS-Prp-0765Prunus persica53.073e-173 520
LLPS-Mae-0445Manihot esculenta52.917e-174 522
LLPS-Brd-0885Brachypodium distachyon52.915e-173 519
LLPS-Cus-2372Cucumis sativus52.911e-174 527
LLPS-Met-2370Medicago truncatula52.98e-173 519
LLPS-Glm-2021Glycine max52.812e-170 513
LLPS-Sem-1112Selaginella moellendorffii52.751e-172 515
LLPS-Amt-2224Amborella trichopoda52.742e-174 523
LLPS-Nia-2424Nicotiana attenuata52.641e-172 518
LLPS-Coc-0776Corchorus capsularis52.643e-172 517
LLPS-Viv-1454Vitis vinifera52.576e-172 516
LLPS-Sot-2049Solanum tuberosum52.37e-172 516
LLPS-Sol-1554Solanum lycopersicum52.181e-167 515
LLPS-Chr-0786Chlamydomonas reinhardtii51.711e-179 536
LLPS-Brr-1070Brassica rapa51.472e-171 515
LLPS-Zem-1700Zea mays51.344e-136 428
LLPS-Bro-0848Brassica oleracea51.31e-171 517
LLPS-Brn-2023Brassica napus51.35e-171 516
LLPS-Scm-0658Scophthalmus maximus50.882e-139 435
LLPS-Osl-1298Ostreococcus lucimarinus50.85e-130 401
LLPS-Pof-2485Poecilia formosa50.779e-138 431
LLPS-Xim-2157Xiphophorus maculatus50.777e-137 431
LLPS-Orn-4128Oreochromis niloticus50.663e-137 430
LLPS-Tar-2892Takifugu rubripes50.666e-138 431
LLPS-Abg-0634Absidia glauca50.651e-132 435
LLPS-Rhb-1597Rhinopithecus bieti50.553e-138 432
LLPS-Orc-2722Oryctolagus cuniculus50.551e-135 423
LLPS-Pat-3932Pan troglodytes50.554e-138 432
LLPS-Pap-0218Pan paniscus50.554e-138 432
LLPS-Hos-0336Homo sapiens50.554e-138 432
LLPS-Poa-2045Pongo abelii50.555e-138 432
LLPS-Caj-2353Callithrix jacchus50.551e-137 431
LLPS-Gog-3398Gorilla gorilla50.554e-138 432
LLPS-Cea-3972Cercocebus atys50.554e-138 432
LLPS-Orl-2752Oryzias latipes50.552e-138 433
LLPS-Chs-4606Chlorocebus sabaeus50.553e-139 432
LLPS-Maf-4810Macaca fascicularis50.554e-138 432
LLPS-Mup-0908Mustela putorius furo50.558e-138 432
LLPS-Mal-3302Mandrillus leucophaeus50.552e-138 432
LLPS-Paa-2654Papio anubis50.555e-138 432
LLPS-Ran-3513Rattus norvegicus50.557e-138 432
LLPS-Ast-1012Aspergillus terreus50.441e-134 424
LLPS-Asc-1010Aspergillus clavatus50.442e-135 425
LLPS-Nol-2857Nomascus leucogenys50.336e-137 429
LLPS-Cas-3101Carlito syrichta50.339e-140 431
LLPS-Ten-2569Tetraodon nigroviridis50.332e-138 430
LLPS-Fud-2983Fukomys damarensis50.332e-138 432
LLPS-Mum-3793Mus musculus50.334e-137 430
LLPS-Bot-2152Bos taurus50.332e-137 431
LLPS-Otg-3001Otolemur garnettii50.223e-136 427
LLPS-Aim-0908Ailuropoda melanoleuca50.222e-135 426
LLPS-Myl-2330Myotis lucifugus50.222e-136 428
LLPS-Ova-0232Ovis aries50.222e-135 426
LLPS-Loa-2264Loxodonta africana50.114e-137 430
LLPS-Fec-2375Felis catus50.111e-136 429
LLPS-Mod-2263Monodelphis domestica50.112e-136 429
LLPS-Urm-3783Ursus maritimus50.112e-137 429
LLPS-Caf-1649Canis familiaris50.117e-137 429
LLPS-Cae-1415Caenorhabditis elegans50.116e-136 426
LLPS-Icp-2891Ictalurus punctatus50.115e-137 429
LLPS-Aon-3786Aotus nancymaae50.117e-136 427
LLPS-Leo-2121Lepisosteus oculatus50.115e-135 424
LLPS-Ora-3397Ornithorhynchus anatinus50.112e-135 424
LLPS-Scc-1017Schizosaccharomyces cryophilus50.115e-139 434
LLPS-Dio-3563Dipodomys ordii50.112e-137 430
LLPS-Gaa-1812Gasterosteus aculeatus50.114e-137 428
LLPS-Asg-0160Ashbya gossypii50.01e-132 416
LLPS-Asf-0535Aspergillus flavus50.02e-134 417
LLPS-Aso-0925Aspergillus oryzae50.02e-133 418
LLPS-Cap-4233Cavia porcellus49.891e-136 429
LLPS-Sah-3239Sarcophilus harrisii49.892e-136 427
LLPS-Lac-1561Latimeria chalumnae49.672e-133 421
LLPS-Dar-3147Danio rerio49.677e-136 427
LLPS-Meg-3084Meleagris gallopavo49.675e-136 426
LLPS-Gaga-1867Gallus gallus49.675e-135 425
LLPS-Asm-3179Astyanax mexicanus49.671e-135 427
LLPS-Scf-0581Scleropages formosus49.673e-135 425
LLPS-Crn-1310Cryptococcus neoformans49.579e-135 424
LLPS-Kop-1105Komagataella pastoris49.574e-134 419
LLPS-Nef-1214Neosartorya fischeri49.565e-133 420
LLPS-Asfu-0937Aspergillus fumigatus49.565e-133 419
LLPS-Fia-3630Ficedula albicollis49.452e-136 424
LLPS-Pes-2350Pelodiscus sinensis49.457e-135 426
LLPS-Tag-1123Taeniopygia guttata49.457e-136 425
LLPS-Usm-1422Ustilago maydis49.369e-137 431
LLPS-Asni-1325Aspergillus niger49.344e-133 419
LLPS-Via-2339Vigna angularis49.342e-138 434
LLPS-Anp-2649Anas platyrhynchos49.232e-133 420
LLPS-Spr-0865Sporisorium reilianum49.153e-136 429
LLPS-Mao-1622Magnaporthe oryzae49.156e-131 419
LLPS-Blg-1499Blumeria graminis49.154e-138 435
LLPS-Anc-2716Anolis carolinensis49.122e-136 426
LLPS-Mel-1056Melampsora laricipopulina48.942e-135 426
LLPS-Org-1802Oryza glaberrima48.71e-134 423
LLPS-Mua-1138Musa acuminata48.73e-135 425
LLPS-Tum-0910Tuber melanosporum48.611e-133 422
LLPS-Scp-0203Schizosaccharomyces pombe48.63e-141 440
LLPS-Asn-1264Aspergillus nidulans48.562e-132 417
LLPS-Scs-0679Sclerotinia sclerotiorum48.531e-130 412
LLPS-Drm-2160Drosophila melanogaster48.492e-134 424
LLPS-Gas-1178Galdieria sulphuraria48.37e-132 416
LLPS-Pytr-0296Pyrenophora triticirepentis48.217e-131 413
LLPS-Cym-0740Cyanidioschyzon merolae47.974e-130 410
LLPS-Scj-0968Schizosaccharomyces japonicus47.948e-132 414
LLPS-Eqc-3716Equus caballus47.737e-132 417
LLPS-Fuo-0762Fusarium oxysporum46.953e-131 417
LLPS-Fuv-1498Fusarium verticillioides46.953e-131 417
LLPS-Pug-1326Puccinia graminis46.631e-134 426
LLPS-Put-0271Puccinia triticina46.158e-134 423