LLPS-Art-1279
At5g15810
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Probable tRNA (guanine(26)-N(2))-dimethyltransferase 1; tRNA 2,2-dimethylguanosine-26 methyltransferase 1; tRNA(guanine-26,N(2)-N(2)) methyltransferase 1; tRNA(m(2,2)G26)dimethyltransferase 1 |
| Gene Name: | At5g15810, F14F8_190 |
| Ensembl Gene: | AT5G15810 |
| Ensembl Protein: | AT5G15810.1 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
▼ FUNCTION
| Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT5G15810.1 | AT5G15810.1 |
| UniProt | Q9LFU5, TRM1_ARATH, F4KB92, Q8RXS4 | |
| GeneBank | AY080697, CP002688, AL391144 | AED92210.2, AAL86317.1, CAC01780.1 |
| RefSeq | NM_121586.3 | NP_197085.3 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 METDLNDYTV IKEGEAEVLM HKKNQVFFNK AQVNNRDMSI AVLRAFIIKR KQEHEAMLSK 60 61 RARSSGKVVE KDVSETSKEE TPTENGDDNG KTNGEHEVTT QDGPKEAAKT AYESARRELK 120 121 PPRVLEALSA SGLRALRYAR EVEGIGQVVA LDNDPASVEA CQRNIKFNGL MSTSKVESHL 180 181 TDARVHMLSH PKDFDVVDLD PYGAPSIFLD SAVQSVADGG LLMCTATDMA VLCGANGEVC 240 241 YSKYGSYPLK GKYCHEMALR ILLASIESHA NRYKRYIVPV LSVQMDFYVR VFVRVYTSAS 300 301 AMKNTPLKLS YVYQCIGCDS FHLQSVGRSL PKNNSVRYLP GVGPVVPQDC THCGKKYNMG 360 361 GPIWSAPIHD QEWVNSILNG VKSMKDRYPA YDRICAVLTT ISEELPDVPL FLSLHSLSAT 420 421 LKCTSPSAAL FRSAVINAKY RVSGSHVNPL GIKTDAPMEI IWDIMRCWVK NHPIKPQSPE 480 481 HPGSVILSKE PSHQADFSRH VGSLSKAQAK KVARFLPNPE KHWGPKIRAG RTITSKHVSL 540 541 LGHEAVNGHL NNNHKEAGDE EEEEEEEEPE EDIIEGEPEL KRQKTTEDFA STS 593 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAAACGG ATCTCAATGA TTATACTGTC ATTAAGGAAG GAGAAGCTGA GGTTCTTATG 60 61 CACAAGAAGA ACCAAGTCTT CTTCAACAAA GCTCAGGTTA ACAATAGGGA CATGTCTATT 120 121 GCTGTGCTAA GGGCATTTAT AATCAAACGC AAGCAAGAGC ATGAGGCTAT GTTATCTAAA 180 181 AGAGCTAGAT CATCTGGGAA AGTGGTTGAG AAGGATGTCT CTGAAACTTC CAAGGAAGAA 240 241 ACTCCTACTG AAAACGGTGA CGATAATGGA AAAACCAATG GAGAACACGA AGTAACAACT 300 301 CAGGATGGAC CAAAGGAAGC TGCTAAGACC GCATATGAAT CTGCACGAAG GGAACTCAAA 360 361 CCACCAAGAG TGCTTGAGGC CCTGTCAGCT TCAGGGCTAC GGGCTTTGAG GTATGCTCGT 420 421 GAAGTTGAAG GAATTGGTCA AGTTGTGGCT TTAGATAATG ACCCAGCATC GGTTGAAGCC 480 481 TGCCAGAGAA ACATTAAGTT CAATGGTTTG ATGTCTACTT CAAAGGTGGA GTCACATCTT 540 541 ACTGATGCTC GTGTTCACAT GCTCAGCCAC CCAAAAGATT TTGATGTGGT TGATCTTGAC 600 601 CCATATGGTG CGCCGTCTAT TTTCCTTGAC TCAGCTGTTC AATCAGTTGC CGATGGTGGT 660 661 TTGCTGATGT GTACAGCAAC TGACATGGCA GTGTTATGTG GAGCTAACGG CGAGGTCTGC 720 721 TATTCCAAAT ATGGCTCTTA TCCACTGAAA GGGAAATATT GTCATGAGAT GGCTTTGAGG 780 781 ATCCTCCTCG CCAGCATCGA GAGCCATGCA AATCGCTACA AGCGGTATAT TGTTCCTGTT 840 841 CTATCGGTCC AAATGGATTT CTACGTTCGT GTTTTTGTCC GCGTCTACAC TTCGGCGAGT 900 901 GCAATGAAGA ATACTCCACT AAAGCTCTCA TATGTCTACC AATGCATTGG TTGTGATTCC 960 961 TTTCATCTTC AGTCTGTTGG AAGATCTCTC CCTAAGAATA ACAGTGTGAG ATATCTACCT 1020 1021 GGAGTTGGTC CTGTTGTTCC TCAGGATTGC ACTCATTGTG GAAAGAAATA TAATATGGGT 1080 1081 GGACCAATAT GGTCTGCTCC AATCCACGAT CAAGAATGGG TGAATTCGAT ACTAAACGGT 1140 1141 GTTAAATCCA TGAAAGACAG ATATCCTGCT TACGACCGAA TTTGCGCTGT TCTTACCACA 1200 1201 ATCTCAGAGG AATTGCCAGA TGTTCCTCTC TTTTTGAGCC TGCATAGTCT CTCTGCAACG 1260 1261 CTAAAATGTA CTTCACCATC AGCTGCTTTG TTTCGATCAG CGGTAATCAA TGCAAAGTAC 1320 1321 CGTGTCTCTG GGTCCCATGT GAACCCGCTT GGGATTAAAA CTGATGCTCC AATGGAGATT 1380 1381 ATCTGGGACA TCATGCGGTG CTGGGTGAAA AATCATCCCA TAAAGCCGCA ATCACCTGAA 1440 1441 CATCCTGGAA GTGTGATTCT ATCTAAAGAA CCATCTCATC AGGCTGACTT TTCGCGCCAC 1500 1501 GTCGGTTCGC TTAGTAAAGC ACAGGCGAAG AAAGTAGCCC GGTTTCTACC AAACCCAGAG 1560 1561 AAGCATTGGG GTCCCAAGAT AAGGGCAGGT CGTACAATCA CAAGCAAACA TGTATCGCTT 1620 1621 CTTGGTCATG AAGCAGTAAA CGGTCATCTC AATAACAATC ATAAAGAAGC AGGAGACGAA 1680 1681 GAAGAAGAAG AAGAAGAAGA AGAGCCCGAA GAAGATATCA TCGAGGGTGA GCCAGAGCTC 1740 1741 AAACGCCAAA AGACAACAGA AGATTTTGCC TCAACATCAT AG 1782 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | TRNA (guanine-N2-)-methyltransferase activity | |
Molecular Function | TRNA binding |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| PTM | ||||
| EPSD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| CGDB | ||||
| Localization | ||||
| COMPARTMENTS | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-1537 | Arabidopsis lyrata | 94.77 | 0.0 | 1127 |
| LLPS-Brr-0556 | Brassica rapa | 88.72 | 0.0 | 1070 |
| LLPS-Bro-2967 | Brassica oleracea | 88.59 | 0.0 | 1072 |
| LLPS-Brn-1771 | Brassica napus | 87.67 | 0.0 | 1061 |
| LLPS-Coc-1900 | Corchorus capsularis | 78.11 | 0.0 | 929 |
| LLPS-Prp-2012 | Prunus persica | 77.26 | 0.0 | 915 |
| LLPS-Hea-2780 | Helianthus annuus | 77.06 | 0.0 | 904 |
| LLPS-Thc-1391 | Theobroma cacao | 76.87 | 0.0 | 911 |
| LLPS-Pot-0198 | Populus trichocarpa | 76.79 | 0.0 | 905 |
| LLPS-Viv-0525 | Vitis vinifera | 76.38 | 0.0 | 912 |
| LLPS-Nia-0619 | Nicotiana attenuata | 76.21 | 0.0 | 895 |
| LLPS-Gor-0827 | Gossypium raimondii | 75.62 | 0.0 | 904 |
| LLPS-Cus-0091 | Cucumis sativus | 75.0 | 0.0 | 889 |
| LLPS-Via-1566 | Vigna angularis | 74.74 | 0.0 | 901 |
| LLPS-Phv-1291 | Phaseolus vulgaris | 74.39 | 0.0 | 914 |
| LLPS-Vir-1955 | Vigna radiata | 74.39 | 0.0 | 910 |
| LLPS-Sot-1525 | Solanum tuberosum | 74.23 | 0.0 | 875 |
| LLPS-Glm-2068 | Glycine max | 73.84 | 0.0 | 904 |
| LLPS-Mae-0696 | Manihot esculenta | 73.77 | 0.0 | 905 |
| LLPS-Sol-0499 | Solanum lycopersicum | 73.44 | 0.0 | 868 |
| LLPS-Met-1017 | Medicago truncatula | 71.08 | 0.0 | 852 |
| LLPS-Orbr-0898 | Oryza brachyantha | 70.9 | 1e-173 | 504 |
| LLPS-Brd-0019 | Brachypodium distachyon | 70.86 | 0.0 | 831 |
| LLPS-Sei-0447 | Setaria italica | 70.45 | 0.0 | 833 |
| LLPS-Mua-1134 | Musa acuminata | 70.29 | 0.0 | 817 |
| LLPS-Sob-0942 | Sorghum bicolor | 69.78 | 0.0 | 830 |
| LLPS-Tra-0993 | Triticum aestivum | 69.15 | 0.0 | 818 |
| LLPS-Hov-1744 | Hordeum vulgare | 68.64 | 0.0 | 810 |
| LLPS-Lep-1565 | Leersia perrieri | 67.14 | 0.0 | 768 |
| LLPS-Ors-1261 | Oryza sativa | 67.03 | 0.0 | 774 |
| LLPS-Org-0129 | Oryza glaberrima | 67.03 | 0.0 | 773 |
| LLPS-Orgl-1510 | Oryza glumaepatula | 67.03 | 0.0 | 773 |
| LLPS-Orp-0486 | Oryza punctata | 66.85 | 0.0 | 772 |
| LLPS-Ori-1120 | Oryza indica | 66.31 | 0.0 | 766 |
| LLPS-Sem-0767 | Selaginella moellendorffii | 65.28 | 0.0 | 692 |
| LLPS-Orr-1080 | Oryza rufipogon | 65.05 | 0.0 | 734 |
| LLPS-Orb-0711 | Oryza barthii | 65.05 | 0.0 | 734 |
| LLPS-Amt-0459 | Amborella trichopoda | 64.93 | 0.0 | 766 |
| LLPS-Zem-2430 | Zea mays | 62.87 | 0.0 | 792 |
| LLPS-Dac-0594 | Daucus carota | 61.34 | 0.0 | 580 |
| LLPS-Php-0745 | Physcomitrella patens | 60.38 | 0.0 | 714 |
| LLPS-Osl-0825 | Ostreococcus lucimarinus | 59.02 | 5e-175 | 510 |
| LLPS-Orni-0185 | Oryza nivara | 58.78 | 0.0 | 655 |
| LLPS-Tru-0885 | Triticum urartu | 58.61 | 0.0 | 668 |
| LLPS-Chr-1030 | Chlamydomonas reinhardtii | 56.52 | 1e-07 | 58.9 |
| LLPS-Leo-1374 | Lepisosteus oculatus | 43.84 | 2e-120 | 375 |
| LLPS-Xet-2889 | Xenopus tropicalis | 43.83 | 5e-131 | 400 |
| LLPS-Icp-3038 | Ictalurus punctatus | 43.69 | 5e-137 | 422 |
| LLPS-Mup-2907 | Mustela putorius furo | 43.07 | 3e-137 | 423 |
| LLPS-Orc-3019 | Oryctolagus cuniculus | 43.06 | 5e-127 | 391 |
| LLPS-Cas-3003 | Carlito syrichta | 42.97 | 2e-126 | 394 |
| LLPS-Caj-4348 | Callithrix jacchus | 42.8 | 3e-139 | 426 |
| LLPS-Fud-0740 | Fukomys damarensis | 42.69 | 8e-138 | 423 |
| LLPS-Ran-3300 | Rattus norvegicus | 42.69 | 2e-135 | 416 |
| LLPS-Orn-2728 | Oreochromis niloticus | 42.64 | 7e-137 | 421 |
| LLPS-Aon-0647 | Aotus nancymaae | 42.53 | 8e-138 | 423 |
| LLPS-Aim-1155 | Ailuropoda melanoleuca | 42.5 | 9e-137 | 421 |
| LLPS-Cap-0954 | Cavia porcellus | 42.31 | 1e-140 | 430 |
| LLPS-Caf-1100 | Canis familiaris | 42.31 | 6e-136 | 419 |
| LLPS-Fec-1106 | Felis catus | 42.13 | 3e-136 | 419 |
| LLPS-Eqc-3018 | Equus caballus | 42.13 | 6e-134 | 412 |
| LLPS-Mea-2242 | Mesocricetus auratus | 42.05 | 4e-138 | 424 |
| LLPS-Sah-2023 | Sarcophilus harrisii | 42.02 | 7e-138 | 421 |
| LLPS-Scf-3178 | Scleropages formosus | 41.98 | 3e-136 | 419 |
| LLPS-Anc-1088 | Anolis carolinensis | 41.95 | 2e-139 | 426 |
| LLPS-Urm-2188 | Ursus maritimus | 41.94 | 1e-134 | 414 |
| LLPS-Bot-2986 | Bos taurus | 41.94 | 4e-136 | 420 |
| LLPS-Scm-3339 | Scophthalmus maximus | 41.89 | 4e-137 | 422 |
| LLPS-Chs-0356 | Chlorocebus sabaeus | 41.84 | 1e-125 | 387 |
| LLPS-Pof-3482 | Poecilia formosa | 41.67 | 2e-134 | 413 |
| LLPS-Loa-2724 | Loxodonta africana | 41.67 | 7e-136 | 418 |
| LLPS-Nol-2742 | Nomascus leucogenys | 41.61 | 3e-59 | 212 |
| LLPS-Mod-2053 | Monodelphis domestica | 41.57 | 3e-138 | 422 |
| LLPS-Otg-3584 | Otolemur garnettii | 41.56 | 5e-133 | 410 |
| LLPS-Pat-0396 | Pan troglodytes | 41.48 | 1e-134 | 415 |
| LLPS-Gog-1083 | Gorilla gorilla | 41.48 | 1e-134 | 415 |
| LLPS-Maf-2080 | Macaca fascicularis | 41.48 | 1e-134 | 415 |
| LLPS-Cea-1689 | Cercocebus atys | 41.48 | 3e-134 | 414 |
| LLPS-Paa-3403 | Papio anubis | 41.48 | 4e-134 | 414 |
| LLPS-Mal-0949 | Mandrillus leucophaeus | 41.48 | 9e-134 | 412 |
| LLPS-Ict-0538 | Ictidomys tridecemlineatus | 41.37 | 4e-134 | 414 |
| LLPS-Mum-3259 | Mus musculus | 41.37 | 2e-137 | 422 |
| LLPS-Sus-2391 | Sus scrofa | 41.37 | 1e-135 | 417 |
| LLPS-Rhb-2105 | Rhinopithecus bieti | 41.29 | 3e-133 | 411 |
| LLPS-Hos-4311 | Homo sapiens | 41.29 | 4e-134 | 413 |
| LLPS-Ten-2524 | Tetraodon nigroviridis | 41.18 | 4e-130 | 400 |
| LLPS-Xim-0170 | Xiphophorus maculatus | 41.17 | 1e-131 | 404 |
| LLPS-Gaa-2524 | Gasterosteus aculeatus | 41.17 | 7e-125 | 388 |
| LLPS-Poa-0569 | Pongo abelii | 41.1 | 1e-133 | 412 |
| LLPS-Dar-0193 | Danio rerio | 41.06 | 1e-129 | 402 |
| LLPS-Asm-2116 | Astyanax mexicanus | 41.06 | 2e-135 | 417 |
| LLPS-Myl-1887 | Myotis lucifugus | 40.99 | 8e-135 | 416 |
| LLPS-Mam-1406 | Macaca mulatta | 40.94 | 1e-126 | 393 |
| LLPS-Tar-1265 | Takifugu rubripes | 40.83 | 6e-120 | 377 |
| LLPS-Dio-0629 | Dipodomys ordii | 40.8 | 4e-129 | 400 |
| LLPS-Orl-0140 | Oryzias latipes | 40.34 | 6e-127 | 394 |
| LLPS-Drm-1790 | Drosophila melanogaster | 40.33 | 2e-124 | 386 |
| LLPS-Cii-0460 | Ciona intestinalis | 40.23 | 7e-121 | 376 |
| LLPS-Cis-0702 | Ciona savignyi | 40.23 | 1e-123 | 382 |
| LLPS-Usm-1053 | Ustilago maydis | 39.89 | 1e-77 | 266 |
| LLPS-Man-2004 | Macaca nemestrina | 39.15 | 5e-130 | 404 |
| LLPS-Spr-0110 | Sporisorium reilianum | 39.14 | 1e-72 | 253 |
| LLPS-Cae-0437 | Caenorhabditis elegans | 38.64 | 3e-108 | 342 |
| LLPS-Abg-0489 | Absidia glauca | 38.43 | 1e-118 | 369 |
| LLPS-Scj-1164 | Schizosaccharomyces japonicus | 37.69 | 5e-114 | 358 |
| LLPS-Pes-0546 | Pelodiscus sinensis | 37.45 | 7e-98 | 319 |
| LLPS-Scc-0813 | Schizosaccharomyces cryophilus | 37.38 | 2e-114 | 360 |
| LLPS-Mel-1165 | Melampsora laricipopulina | 36.94 | 2e-100 | 324 |
| LLPS-Lac-1376 | Latimeria chalumnae | 36.04 | 3e-101 | 326 |
| LLPS-Kop-0931 | Komagataella pastoris | 35.88 | 3e-89 | 292 |
| LLPS-Pug-0314 | Puccinia graminis | 35.19 | 1e-88 | 296 |
| LLPS-Scp-1035 | Schizosaccharomyces pombe | 35.09 | 8e-104 | 331 |
| LLPS-Gas-1323 | Galdieria sulphuraria | 34.77 | 3e-89 | 294 |
| LLPS-Ova-1081 | Ovis aries | 34.27 | 2e-75 | 259 |
| LLPS-Asni-1562 | Aspergillus niger | 34.05 | 1e-89 | 294 |
| LLPS-Miv-0345 | Microbotryum violaceum | 33.94 | 2e-90 | 301 |
| LLPS-Cym-0409 | Cyanidioschyzon merolae | 33.88 | 1e-84 | 280 |
| LLPS-Cogr-1360 | Colletotrichum graminicola | 32.91 | 3e-70 | 246 |
| LLPS-Asg-0159 | Ashbya gossypii | 32.91 | 5e-81 | 271 |
| LLPS-Ved-0768 | Verticillium dahliae | 32.84 | 2e-68 | 243 |
| LLPS-Cog-1543 | Colletotrichum gloeosporioides | 32.78 | 4e-74 | 256 |
| LLPS-Dos-1434 | Dothistroma septosporum | 32.66 | 2e-75 | 259 |
| LLPS-Pyt-0377 | Pyrenophora teres | 32.64 | 6e-78 | 266 |
| LLPS-Scs-0831 | Sclerotinia sclerotiorum | 32.58 | 8e-73 | 251 |
| LLPS-Fuo-0252 | Fusarium oxysporum | 32.41 | 7e-71 | 246 |
| LLPS-Fuv-0261 | Fusarium verticillioides | 32.41 | 4e-70 | 244 |
| LLPS-Sac-0236 | Saccharomyces cerevisiae | 32.31 | 3e-81 | 273 |
| LLPS-Yal-0402 | Yarrowia lipolytica | 32.28 | 6e-74 | 251 |
| LLPS-Nec-1511 | Neurospora crassa | 32.22 | 4e-77 | 265 |
| LLPS-Lem-0849 | Leptosphaeria maculans | 32.01 | 2e-74 | 257 |
| LLPS-Phn-0246 | Phaeosphaeria nodorum | 31.96 | 6e-74 | 256 |
| LLPS-Asc-1651 | Aspergillus clavatus | 31.88 | 1e-72 | 257 |
| LLPS-Zyt-0422 | Zymoseptoria tritici | 31.77 | 2e-70 | 246 |
| LLPS-Asfu-0552 | Aspergillus fumigatus | 31.72 | 3e-72 | 252 |
| LLPS-Nef-1626 | Neosartorya fischeri | 31.55 | 1e-72 | 252 |
| LLPS-Asn-0292 | Aspergillus nidulans | 31.54 | 1e-71 | 250 |
| LLPS-Put-0202 | Puccinia triticina | 31.44 | 2e-76 | 262 |
| LLPS-Ast-0367 | Aspergillus terreus | 31.26 | 3e-69 | 248 |
| LLPS-Asf-0763 | Aspergillus flavus | 31.24 | 2e-76 | 263 |
| LLPS-Aso-0913 | Aspergillus oryzae | 31.24 | 2e-76 | 263 |
| LLPS-Coo-1127 | Colletotrichum orbiculare | 31.18 | 4e-65 | 231 |
| LLPS-Trr-1615 | Trichoderma reesei | 31.14 | 4e-74 | 255 |
| LLPS-Tum-0147 | Tuber melanosporum | 30.96 | 4e-80 | 272 |
| LLPS-Beb-0917 | Beauveria bassiana | 30.64 | 2e-63 | 227 |
| LLPS-Blg-0336 | Blumeria graminis | 30.54 | 6e-68 | 239 |
| LLPS-Crn-0569 | Cryptococcus neoformans | 30.25 | 2e-70 | 246 |
| LLPS-Trv-1626 | Trichoderma virens | 30.18 | 2e-72 | 250 |
| LLPS-Fus-0984 | Fusarium solani | 30.02 | 2e-72 | 250 |
| LLPS-Pytr-0359 | Pyrenophora triticirepentis | 29.53 | 3e-62 | 223 |
| LLPS-Map-1366 | Magnaporthe poae | 29.48 | 1e-15 | 84.3 |
| LLPS-Mao-1011 | Magnaporthe oryzae | 29.06 | 1e-62 | 225 |
| LLPS-Gag-0639 | Gaeumannomyces graminis | 27.46 | 1e-60 | 219 |
| LLPS-Anp-1134 | Anas platyrhynchos | 27.3 | 2e-14 | 80.9 |
| LLPS-Fia-1945 | Ficedula albicollis | 26.95 | 1e-17 | 90.9 |
| LLPS-Meg-1864 | Meleagris gallopavo | 26.95 | 8e-19 | 94.7 |
| LLPS-Tag-1661 | Taeniopygia guttata | 26.95 | 4e-15 | 82.8 |
| LLPS-Ora-0046 | Ornithorhynchus anatinus | 26.95 | 1e-15 | 84.3 |
| LLPS-Pap-0288 | Pan paniscus | 26.86 | 6e-13 | 75.9 |
| LLPS-Gaga-1023 | Gallus gallus | 25.89 | 4e-21 | 102 |
| LLPS-Orm-1739 | Oryza meridionalis | 24.16 | 6e-16 | 84.3 |