LLPS-Art-1039
LYSA1

▼ OVERVIEW

Status: Reviewed
Protein Name: Diaminopimelate decarboxylase 1, chloroplastic
Gene Name: LYSA1, At3g14390, MLN21.17
Ensembl Gene: AT3G14390
Ensembl Protein: AT3G14390.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAATQFLSQ  PSSLNPHQLK  NQTSQRSRSI  PVLSLKSTLK  PLKRLSVKAA  VVSQNSSKTV  60
61    TKFDHCFKKS  SDGFLYCEGT  KVEDIMESVE  RRPFYLYSKP  QITRNLEAYK  EALEGVSSVI  120
121   GYAIKANNNL  KILEHLRSLG  CGAVLVSGNE  LRLALRAGFD  PTKCIFNGNG  KSLEDLVLAA  180
181   QEGVFVNVDS  EFDLNNIVEA  SRISGKQVNV  LLRINPDVDP  QVHPYVATGN  KNSKFGIRNE  240
241   KLQWFLDQVK  AHPKELKLVG  AHCHLGSTIT  KVDIFRDAAV  LMIEYIDEIR  RQGFEVSYLN  300
301   IGGGLGIDYY  HAGAVLPTPM  DLINTVRELV  LSRDLNLIIE  PGRSLIANTC  CFVNHVTGVK  360
361   TNGTKNFIVI  DGSMAELIRP  SLYDAYQHIE  LVSPPPAEAE  VTKFDVVGPV  CESADFLGKD  420
421   RELPTPPQGA  GLVVHDAGAY  CMSMASTYNL  KMRPPEYWVE  EDGSITKIRH  AETFDDHLRF  480
481   FEGL  484
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGCAG  CTACTCAATT  TCTCTCCCAA  CCTTCGTCTC  TCAATCCACA  CCAACTGAAG  60
61    AACCAAACCT  CACAACGCTC  CAGAAGCATC  CCTGTCTTGT  CTCTTAAATC  CACATTGAAG  120
121   CCACTTAAAC  GCCTCTCCGT  GAAAGCCGCC  GTCGTTTCTC  AAAACTCGTC  CAAAACCGTG  180
181   ACGAAGTTCG  ATCACTGTTT  CAAGAAATCA  TCAGATGGGT  TTCTCTATTG  TGAAGGAACT  240
241   AAAGTTGAGG  ATATCATGGA  GTCAGTGGAG  AGAAGACCCT  TTTACTTATA  TAGCAAACCT  300
301   CAGATCACTA  GAAACCTCGA  GGCTTATAAA  GAAGCATTGG  AAGGAGTGAG  CTCTGTGATT  360
361   GGTTACGCTA  TCAAAGCTAA  TAACAATCTT  AAAATTTTGG  AGCATTTGAG  AAGTTTAGGC  420
421   TGTGGTGCTG  TGCTCGTTAG  TGGAAATGAG  CTTAGACTTG  CTCTTCGTGC  TGGTTTCGAT  480
481   CCCACAAAGT  GCATTTTCAA  TGGAAATGGC  AAGTCTTTGG  AAGATTTAGT  TCTAGCTGCT  540
541   CAAGAAGGTG  TTTTCGTTAA  TGTCGATAGT  GAGTTTGACT  TGAATAACAT  TGTGGAAGCT  600
601   TCAAGAATTT  CTGGTAAGCA  GGTCAATGTA  CTGCTGCGTA  TCAATCCTGA  TGTTGATCCT  660
661   CAGGTGCATC  CATATGTTGC  TACTGGGAAC  AAGAACTCAA  AGTTTGGTAT  CAGGAACGAG  720
721   AAGCTTCAAT  GGTTTCTGGA  TCAGGTCAAG  GCACATCCCA  AAGAGCTGAA  GCTTGTTGGA  780
781   GCTCATTGCC  ATCTAGGCTC  TACCATTACT  AAGGTGGATA  TATTCAGAGA  TGCGGCAGTT  840
841   CTCATGATAG  AATACATTGA  CGAGATCCGG  CGTCAAGGTT  TTGAAGTTAG  TTACTTGAAC  900
901   ATTGGTGGTG  GTTTAGGGAT  TGATTATTAC  CATGCCGGCG  CTGTCCTTCC  CACACCCATG  960
961   GATCTCATCA  ACACTGTAAG  AGAGCTTGTT  CTTTCACGAG  ACCTGAATCT  AATAATCGAG  1020
1021  CCAGGGAGAT  CTCTGATTGC  AAACACTTGC  TGTTTCGTCA  ACCATGTAAC  TGGTGTGAAG  1080
1081  ACGAATGGAA  CTAAGAACTT  CATAGTCATT  GATGGAAGTA  TGGCTGAGCT  TATCCGTCCC  1140
1141  AGTCTTTATG  ATGCTTATCA  GCACATTGAG  TTGGTCTCTC  CTCCACCGGC  TGAAGCAGAG  1200
1201  GTTACCAAAT  TCGACGTAGT  GGGTCCTGTC  TGTGAATCTG  CTGATTTCCT  GGGCAAAGAC  1260
1261  AGAGAGCTTC  CCACTCCTCC  ACAGGGAGCT  GGTCTGGTGG  TTCATGACGC  TGGTGCATAC  1320
1321  TGTATGAGCA  TGGCTTCCAC  TTACAATCTC  AAGATGCGTC  CTCCGGAATA  CTGGGTTGAA  1380
1381  GAAGATGGGT  CGATCACTAA  GATAAGGCAT  GCTGAGACAT  TCGATGACCA  TTTGCGTTTC  1440
1441  TTTGAAGGTC  TATGA  1455

▼ KEYWORD

ID
Family
Acetylation
Amino-acid biosynthesis
Chloroplast
Complete proteome
Decarboxylase
Lyase
Lysine biosynthesis
Plastid
Pyridoxal phosphate
Reference proteome
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Chloroplast stroma
Molecular Function
Diaminopimelate decarboxylase activity
Biological Process
Lysine biosynthetic process via diaminopimelate

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Function
CGDB
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-2692Arabidopsis lyrata96.490.0 968
LLPS-Brr-2402Brassica rapa90.570.0 898
LLPS-Bro-2762Brassica oleracea90.370.0 894
LLPS-Brn-2067Brassica napus89.860.0 904
LLPS-Coc-1298Corchorus capsularis87.250.0 740
LLPS-Sot-1444Solanum tuberosum85.680.0 811
LLPS-Nia-2016Nicotiana attenuata82.920.0 826
LLPS-Orbr-2292Oryza brachyantha82.210.0 711
LLPS-Gor-0714Gossypium raimondii81.190.0 811
LLPS-Viv-0718Vitis vinifera80.570.0 818
LLPS-Hea-0629Helianthus annuus79.830.0 788
LLPS-Met-2089Medicago truncatula79.710.0 785
LLPS-Orm-2112Oryza meridionalis79.710.0 720
LLPS-Orp-0942Oryza punctata79.520.0 712
LLPS-Ors-1879Oryza sativa79.520.0 729
LLPS-Pot-2740Populus trichocarpa79.470.0 793
LLPS-Org-1720Oryza glaberrima79.330.0 725
LLPS-Glm-0360Glycine max78.660.0 791
LLPS-Dac-2149Daucus carota77.070.0 763
LLPS-Zem-1959Zea mays76.360.0 687
LLPS-Brd-1573Brachypodium distachyon75.650.0 740
LLPS-Ori-2442Oryza indica74.882e-115 349
LLPS-Mua-0572Musa acuminata74.340.0 750
LLPS-Lep-1574Leersia perrieri73.760.0 733
LLPS-Tra-1820Triticum aestivum73.350.0 743
LLPS-Tru-2066Triticum urartu73.080.0 741
LLPS-Orb-0756Oryza barthii72.620.0 647
LLPS-Orgl-0747Oryza glumaepatula72.380.0 645
LLPS-Php-1583Physcomitrella patens70.840.0 662
LLPS-Chr-0855Chlamydomonas reinhardtii63.160.0 527
LLPS-Orni-0979Oryza nivara60.953e-179 516
LLPS-Chc-0560Chondrus crispus60.686e-176 510
LLPS-Cym-0227Cyanidioschyzon merolae55.693e-163 481
LLPS-Gas-0999Galdieria sulphuraria55.12e-162 476
LLPS-Osl-0231Ostreococcus lucimarinus28.711e-23 107
LLPS-Sob-0278Sorghum bicolor27.411e-1479.7
LLPS-Hov-1883Hordeum vulgare26.78e-1271.2
LLPS-Phv-2287Phaseolus vulgaris26.672e-1582.4
LLPS-Sei-2175Setaria italica26.097e-1065.1
LLPS-Sus-0772Sus scrofa26.031e-1480.1
LLPS-Via-0153Vigna angularis26.022e-1272.8
LLPS-Ran-3932Rattus norvegicus25.979e-1374.3
LLPS-Aso-1461Aspergillus oryzae25.945e-1890.1
LLPS-Gaa-0362Gasterosteus aculeatus25.925e-1993.6
LLPS-Scp-0430Schizosaccharomyces pombe25.911e-1479.7
LLPS-Sem-2209Selaginella moellendorffii25.881e-1376.3
LLPS-Vir-1067Vigna radiata25.812e-0757.4
LLPS-Orr-0535Oryza rufipogon25.654e-0859.3
LLPS-Sol-2016Solanum lycopersicum25.622e-1994.0
LLPS-Cii-1276Ciona intestinalis25.593e-1168.9
LLPS-Scm-2601Scophthalmus maximus25.541e-1686.3
LLPS-Abg-1108Absidia glauca25.52e-1685.5
LLPS-Xim-2454Xiphophorus maculatus25.36e-1890.5
LLPS-Nef-1338Neosartorya fischeri25.281e-0964.3
LLPS-Sah-3690Sarcophilus harrisii25.143e-1478.2
LLPS-Cea-0899Cercocebus atys25.122e-1582.4
LLPS-Maf-3326Macaca fascicularis25.122e-1582.4
LLPS-Paa-3042Papio anubis25.122e-1582.4
LLPS-Man-4617Macaca nemestrina25.122e-1582.4
LLPS-Mam-2893Macaca mulatta25.122e-1582.8
LLPS-Ict-1778Ictidomys tridecemlineatus25.066e-1581.3
LLPS-Ora-3167Ornithorhynchus anatinus25.01e-2097.8
LLPS-Prp-2167Prunus persica25.01e-1583.2
LLPS-Asf-1221Aspergillus flavus24.931e-1376.6
LLPS-Dio-3869Dipodomys ordii24.873e-1169.3
LLPS-Tar-3694Takifugu rubripes24.752e-1685.5
LLPS-Mae-1795Manihot esculenta24.735e-1374.7
LLPS-Thc-0389Theobroma cacao24.718e-1271.2
LLPS-Pof-2861Poecilia formosa24.711e-1789.7
LLPS-Orl-0712Oryzias latipes24.635e-1684.3
LLPS-Dos-1094Dothistroma septosporum24.577e-0652.4
LLPS-Asg-1379Ashbya gossypii24.553e-1375.9
LLPS-Asn-1630Aspergillus nidulans24.542e-1273.2
LLPS-Orn-1220Oreochromis niloticus24.542e-1685.5
LLPS-Ast-1479Aspergillus terreus24.534e-1272.4
LLPS-Cae-0487Caenorhabditis elegans24.515e-1271.6
LLPS-Lac-3367Latimeria chalumnae24.512e-1272.8
LLPS-Myl-0115Myotis lucifugus24.53e-1582.0
LLPS-Scj-0337Schizosaccharomyces japonicus24.473e-1272.4
LLPS-Mal-0466Mandrillus leucophaeus24.441e-1583.2
LLPS-Rhb-3428Rhinopithecus bieti24.442e-1582.8
LLPS-Amt-1579Amborella trichopoda24.37e-1580.5
LLPS-Anc-1323Anolis carolinensis24.256e-1684.3
LLPS-Loa-2029Loxodonta africana24.143e-1685.1
LLPS-Fud-4160Fukomys damarensis24.075e-1787.8
LLPS-Aim-3995Ailuropoda melanoleuca24.072e-1685.9
LLPS-Urm-0690Ursus maritimus24.072e-1685.9
LLPS-Asc-1242Aspergillus clavatus24.035e-1065.5
LLPS-Icp-4197Ictalurus punctatus24.026e-1477.8
LLPS-Ten-1268Tetraodon nigroviridis24.03e-1065.9
LLPS-Leo-0329Lepisosteus oculatus23.956e-1477.8
LLPS-Mao-1540Magnaporthe oryzae23.912e-0860.8
LLPS-Dar-1636Danio rerio23.91e-1583.2
LLPS-Cap-2119Cavia porcellus23.844e-1684.7
LLPS-Gog-0508Gorilla gorilla23.822e-1582.4
LLPS-Mup-3042Mustela putorius furo23.826e-1684.3
LLPS-Bot-2662Bos taurus23.826e-1684.3
LLPS-Fia-0406Ficedula albicollis23.821e-1686.7
LLPS-Hos-4561Homo sapiens23.825e-1581.3
LLPS-Pat-2957Pan troglodytes23.822e-1582.8
LLPS-Tag-0435Taeniopygia guttata23.822e-1685.5
LLPS-Nol-1828Nomascus leucogenys23.822e-1582.4
LLPS-Asfu-0974Aspergillus fumigatus23.824e-0756.2
LLPS-Cas-1319Carlito syrichta23.827e-1787.0
LLPS-Orc-3022Oryctolagus cuniculus23.819e-1580.5
LLPS-Tum-0646Tuber melanosporum23.781e-1376.6
LLPS-Drm-2133Drosophila melanogaster23.692e-1066.6
LLPS-Gaga-1753Gallus gallus23.694e-1787.8
LLPS-Ved-0209Verticillium dahliae23.665e-1065.5
LLPS-Usm-1236Ustilago maydis23.656e-1271.6
LLPS-Map-1039Magnaporthe poae23.642e-0963.9
LLPS-Pes-2893Pelodiscus sinensis23.611e-0758.2
LLPS-Coo-0954Colletotrichum orbiculare23.68e-1168.2
LLPS-Spr-0421Sporisorium reilianum23.63e-1066.6
LLPS-Gag-0252Gaeumannomyces graminis23.583e-0963.2
LLPS-Caj-4355Callithrix jacchus23.572e-1582.4
LLPS-Aon-4095Aotus nancymaae23.578e-1683.6
LLPS-Mum-3269Mus musculus23.576e-1581.3
LLPS-Ova-0689Ovis aries23.572e-1582.8
LLPS-Anp-0663Anas platyrhynchos23.572e-1685.9
LLPS-Mod-1367Monodelphis domestica23.571e-1583.2
LLPS-Pap-0128Pan paniscus23.572e-1582.4
LLPS-Eqc-1419Equus caballus23.573e-1582.4
LLPS-Poa-1644Pongo abelii23.575e-1581.3
LLPS-Pug-0643Puccinia graminis23.532e-0654.7
LLPS-Meg-2074Meleagris gallopavo23.442e-1788.6
LLPS-Caf-0367Canis familiaris23.333e-1582.0
LLPS-Asm-1713Astyanax mexicanus23.326e-1477.8
LLPS-Scc-0889Schizosaccharomyces cryophilus23.33e-1375.5
LLPS-Xet-3028Xenopus tropicalis23.244e-1375.5
LLPS-Blg-0362Blumeria graminis23.232e-1169.7
LLPS-Chs-1761Chlorocebus sabaeus23.217e-1271.6
LLPS-Cis-1339Ciona savignyi23.144e-0859.7
LLPS-Lem-1185Leptosphaeria maculans23.068e-0858.5
LLPS-Cus-2214Cucumis sativus22.966e-1168.2
LLPS-Fec-1589Felis catus22.914e-1684.7
LLPS-Kop-0848Komagataella pastoris22.616e-0755.8
LLPS-Phn-0003Phaeosphaeria nodorum22.611e-1067.4
LLPS-Mea-3465Mesocricetus auratus22.61e-1273.9
LLPS-Pyt-1578Pyrenophora teres22.565e-0756.2
LLPS-Pytr-0870Pyrenophora triticirepentis22.566e-0755.8
LLPS-Scf-3639Scleropages formosus22.256e-1478.2
LLPS-Scs-0906Sclerotinia sclerotiorum21.889e-1167.8
LLPS-Otg-1592Otolemur garnettii21.618e-0652.4
LLPS-Fuv-0650Fusarium verticillioides21.481e-0758.2
LLPS-Fuo-1107Fusarium oxysporum21.481e-0758.2