LLPS-Art-1010
AVP1

▼ OVERVIEW

Status: Reviewed
Protein Name: Pyrophosphate-energized vacuolar membrane proton pump 1; Pyrophosphate-energized inorganic pyrophosphatase 1; H(+)-PPase 1; Vacuolar proton pyrophosphatase 1; Vacuolar proton pyrophosphatase 3
Gene Name: AVP1, AVP, AVP-3, AVP3, At1g15690, F7H2.3
Ensembl Gene: AT1G15690
Ensembl Protein: AT1G15690.2
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Contributes to the transtonoplast (from cytosol to vacuole lumen) H(+)-electrochemical potential difference. It establishes a proton gradient of similar and often greater magnitude than the H(+)-ATPase on the same membrane. In addition, facilitates auxin transport by modulating apoplastic pH and regulates auxin-mediated developmental processes. Confers tolerance to NaCl and to drought by increasing ion retention.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVAPALLPEL  WTEILVPICA  VIGIAFSLFQ  WYVVSRVKLT  SDLGASSSGG  ANNGKNGYGD  60
61    YLIEEEEGVN  DQSVVAKCAE  IQTAISEGAT  SFLFTEYKYV  GVFMIFFAAV  IFVFLGSVEG  120
121   FSTDNKPCTY  DTTRTCKPAL  ATAAFSTIAF  VLGAVTSVLS  GFLGMKIATY  ANARTTLEAR  180
181   KGVGKAFIVA  FRSGAVMGFL  LAASGLLVLY  ITINVFKIYY  GDDWEGLFEA  ITGYGLGGSS  240
241   MALFGRVGGG  IYTKAADVGA  DLVGKIERNI  PEDDPRNPAV  IADNVGDNVG  DIAGMGSDLF  300
301   GSYAEASCAA  LVVASISSFG  INHDFTAMCY  PLLISSMGIL  VCLITTLFAT  DFFEIKLVKE  360
361   IEPALKNQLI  ISTVIMTVGI  AIVSWVGLPT  SFTIFNFGTQ  KVVKNWQLFL  CVCVGLWAGL  420
421   IIGFVTEYYT  SNAYSPVQDV  ADSCRTGAAT  NVIFGLALGY  KSVIIPIFAI  AISIFVSFSF  480
481   AAMYGVAVAA  LGMLSTIATG  LAIDAYGPIS  DNAGGIAEMA  GMSHRIRERT  DALDAAGNTT  540
541   AAIGKGFAIG  SAALVSLALF  GAFVSRAGIH  TVDVLTPKVI  IGLLVGAMLP  YWFSAMTMKS  600
601   VGSAALKMVE  EVRRQFNTIP  GLMEGTAKPD  YATCVKISTD  ASIKEMIPPG  CLVMLTPLIV  660
661   GFFFGVETLS  GVLAGSLVSG  VQIAISASNT  GGAWDNAKKY  IEAGVSEHAK  SLGPKGSEPH  720
721   KAAVIGDTIG  DPLKDTSGPS  LNILIKLMAV  ESLVFAPFFA  THGGILFKYF  770
Nucleotide CDS Sequence (FASTA)
1     ATGGTGGCGC  CTGCTTTGTT  ACCGGAGCTC  TGGACGGAGA  TCCTTGTACC  GATTTGTGCG  60
61    GTGATTGGTA  TCGCCTTTTC  GCTTTTCCAA  TGGTACGTTG  TATCTCGCGT  GAAACTCACC  120
121   TCTGACCTCG  GCGCATCGTC  TTCCGGTGGA  GCTAACAATG  GGAAGAATGG  ATACGGTGAT  180
181   TATCTAATCG  AGGAAGAGGA  AGGTGTTAAT  GACCAGAGTG  TTGTCGCTAA  GTGCGCTGAG  240
241   ATTCAGACTG  CTATTTCCGA  AGGTGCAACT  TCATTCCTAT  TCACGGAGTA  CAAATATGTT  300
301   GGTGTCTTCA  TGATTTTCTT  TGCTGCTGTT  ATCTTTGTTT  TCCTCGGCTC  TGTTGAGGGA  360
361   TTCAGCACTG  ATAACAAGCC  TTGTACTTAC  GACACCACCA  GAACCTGCAA  GCCTGCATTG  420
421   GCTACTGCAG  CTTTCAGTAC  CATTGCTTTC  GTGCTTGGTG  CTGTTACCTC  TGTTCTATCT  480
481   GGTTTCCTTG  GGATGAAGAT  TGCTACATAC  GCTAATGCTA  GGACCACTTT  GGAGGCGAGG  540
541   AAAGGTGTTG  GAAAGGCGTT  CATTGTTGCA  TTCAGGTCTG  GTGCTGTGAT  GGGTTTCCTT  600
601   CTTGCAGCGA  GTGGTCTATT  GGTGCTTTAC  ATTACTATCA  ATGTGTTCAA  GATCTATTAC  660
661   GGAGATGACT  GGGAAGGTCT  TTTTGAGGCT  ATTACTGGTT  ATGGTCTTGG  TGGGTCTTCC  720
721   ATGGCTCTCT  TTGGCCGTGT  TGGTGGTGGG  ATCTACACTA  AGGCTGCTGA  TGTCGGCGCT  780
781   GACCTTGTCG  GTAAAATTGA  GAGGAATATT  CCAGAGGATG  ATCCAAGAAA  CCCAGCTGTC  840
841   ATTGCTGATA  ATGTCGGTGA  CAATGTTGGT  GACATTGCTG  GTATGGGATC  TGATCTCTTT  900
901   GGATCATATG  CTGAAGCATC  ATGCGCTGCT  CTTGTTGTTG  CCTCGATCTC  ATCTTTCGGA  960
961   ATCAACCACG  ACTTCACTGC  CATGTGCTAC  CCATTGCTCA  TCAGTTCAAT  GGGAATCTTG  1020
1021  GTTTGTTTGA  TCACAACTCT  CTTTGCCACT  GACTTCTTTG  AGATTAAGCT  TGTCAAGGAG  1080
1081  ATTGAACCAG  CATTGAAGAA  CCAGCTCATT  ATCTCAACTG  TTATTATGAC  TGTTGGTATT  1140
1141  GCTATTGTGT  CATGGGTTGG  CTTACCGACC  TCCTTTACCA  TCTTCAACTT  TGGAACACAA  1200
1201  AAAGTTGTCA  AGAACTGGCA  GCTATTCCTT  TGTGTTTGTG  TTGGTCTTTG  GGCTGGACTC  1260
1261  ATTATTGGTT  TCGTCACTGA  GTACTACACT  AGTAACGCCT  ACAGCCCTGT  GCAAGATGTT  1320
1321  GCAGATTCAT  GCAGAACTGG  TGCAGCTACC  AATGTTATCT  TCGGCCTTGC  TCTTGGTTAC  1380
1381  AAATCCGTCA  TTATTCCAAT  CTTTGCTATT  GCTATCAGTA  TATTCGTTAG  CTTCAGCTTT  1440
1441  GCTGCTATGT  ATGGTGTTGC  TGTTGCTGCT  CTTGGTATGC  TCAGTACCAT  TGCCACTGGT  1500
1501  TTGGCAATTG  ATGCTTATGG  TCCCATCAGT  GACAATGCTG  GTGGTATTGC  TGAAATGGCT  1560
1561  GGAATGAGCC  ACCGCATCCG  TGAAAGAACT  GATGCTCTTG  ATGCCGCTGG  AAACACCACT  1620
1621  GCTGCTATTG  GAAAGGGATT  TGCCATTGGC  TCTGCTGCCC  TAGTCTCCTT  GGCTCTCTTT  1680
1681  GGTGCCTTTG  TGAGCCGTGC  AGGGATCCAC  ACCGTAGATG  TTTTGACCCC  TAAAGTTATC  1740
1741  ATTGGGCTCC  TTGTTGGTGC  CATGCTTCCT  TACTGGTTCT  CTGCCATGAC  AATGAAGAGT  1800
1801  GTGGGAAGTG  CAGCTCTTAA  GATGGTTGAA  GAAGTTCGCA  GGCAGTTCAA  CACCATCCCT  1860
1861  GGACTTATGG  AAGGAACCGC  AAAACCAGAC  TACGCCACTC  ACGGTGGTAT  CCTTTTCAAG  1920
1921  TACTTCTAA  1929

▼ KEYWORD

ID
Family
Alternative splicing
Cell membrane
Complete proteome
Direct protein sequencing
Disulfide bond
Endosome
Hydrogen ion transport
Ion transport
Magnesium
Membrane
Metal-binding
Reference proteome
Translocase
Transmembrane
Transmembrane helix
Transport
Vacuole

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Chloroplast envelope
Cellular Component
Endosome membrane
Cellular Component
Golgi apparatus
Cellular Component
Integral component of membrane
Cellular Component
Membrane
Cellular Component
Mitochondrion
Cellular Component
Plant-type vacuole
Cellular Component
Plant-type vacuole membrane
Cellular Component
Plasma membrane
Cellular Component
Vacuolar membrane
Cellular Component
Vacuole
Molecular Function
Hydrogen-translocating pyrophosphatase activity
Molecular Function
Inorganic diphosphatase activity
Molecular Function
Metal ion binding
Biological Process
Auxin polar transport
Biological Process
Establishment or maintenance of transmembrane electrochemical gradient
Biological Process
Leaf development
Biological Process
Proton transmembrane transport
Biological Process
Response to salt stress
Biological Process
Response to water deprivation

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-2625Arabidopsis lyrata99.350.01416
LLPS-Bro-0433Brassica oleracea95.070.01384
LLPS-Brn-1985Brassica napus95.070.01385
LLPS-Brr-2770Brassica rapa94.290.01373
LLPS-Nia-2506Nicotiana attenuata90.60.01309
LLPS-Sot-0231Solanum tuberosum90.470.01315
LLPS-Glm-2848Glycine max89.950.01306
LLPS-Pot-1835Populus trichocarpa89.80.01305
LLPS-Gor-1296Gossypium raimondii89.560.01299
LLPS-Viv-2198Vitis vinifera89.410.01300
LLPS-Met-2507Medicago truncatula89.380.01291
LLPS-Mae-2233Manihot esculenta89.30.01304
LLPS-Prp-0654Prunus persica89.280.01300
LLPS-Thc-2352Theobroma cacao89.180.01291
LLPS-Sol-1604Solanum lycopersicum89.030.01297
LLPS-Coc-0797Corchorus capsularis88.960.01283
LLPS-Hea-1967Helianthus annuus88.960.01304
LLPS-Dac-1042Daucus carota88.630.01299
LLPS-Cus-1948Cucumis sativus88.50.01286
LLPS-Phv-1914Phaseolus vulgaris88.370.01287
LLPS-Via-0912Vigna angularis87.790.01243
LLPS-Orp-1580Oryza punctata87.530.01286
LLPS-Org-0234Oryza glaberrima87.270.01285
LLPS-Mua-1543Musa acuminata87.260.01275
LLPS-Orr-0842Oryza rufipogon87.140.01285
LLPS-Orgl-0156Oryza glumaepatula87.140.01283
LLPS-Orni-1809Oryza nivara87.140.01285
LLPS-Orb-2109Oryza barthii87.140.01285
LLPS-Orbr-1345Oryza brachyantha86.950.01272
LLPS-Zem-2423Zea mays86.550.01269
LLPS-Hov-1958Hordeum vulgare86.480.01263
LLPS-Sei-1008Setaria italica86.290.01272
LLPS-Ors-0956Oryza sativa86.220.01265
LLPS-Amt-1305Amborella trichopoda86.140.01265
LLPS-Sob-1047Sorghum bicolor86.030.01257
LLPS-Tru-0041Triticum urartu86.010.01253
LLPS-Tra-1864Triticum aestivum86.010.01252
LLPS-Lep-0075Leersia perrieri85.510.01267
LLPS-Brd-2437Brachypodium distachyon85.380.01249
LLPS-Orm-0074Oryza meridionalis85.240.01260
LLPS-Ori-1935Oryza indica84.780.01254
LLPS-Sem-0495Selaginella moellendorffii76.880.01119
LLPS-Php-0869Physcomitrella patens75.160.01092
LLPS-Chr-1457Chlamydomonas reinhardtii63.930.0 904
LLPS-Osl-0878Ostreococcus lucimarinus55.520.0 687