LLPS-Art-0844
LPD1

▼ OVERVIEW

Status: Reviewed
Protein Name: Dihydrolipoyl dehydrogenase 1, chloroplastic
Gene Name: LPD1, At3g16950, K14A17.6
Ensembl Gene: AT3G16950
Ensembl Protein: AT3G16950.2
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...Here, we describe the first proteomic analysis of plant nucleoli, in which we have identified 217 proteins."
Protoplasts15496452
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Lipoamide dehydrogenase is a component of the plastidial pyruvate dehydrogenase complex (PDC).

▼ SEQUENCE

Protein Sequence (FASTA)
1     MQSAMALSFS  QTSFTRPNHV  LGSSGSVFST  PRSLRFCGLR  REAFGFSTSN  QLAIRSNRIQ  60
61    FLSRKSFQVS  ASASSNGNGA  PPKSFDYDLI  IIGAGVGGHG  AALHAVEKGL  KTAIIEGDVV  120
121   GGTCVNRGCV  PSKALLAVSG  RMRELQNEHH  MKSFGLQVSA  AGYDRQGVAD  HANNLATKIR  180
181   NNLTNSMKAI  GVDILTGFGS  VLGPQKVKYG  KDNIITAKDI  IIATGSVPFV  PKGIEVDGKT  240
241   VITSDHALKL  ESVPEWIAIV  GSGYIGLEFS  DVYTALGSEV  TFIEALDQLM  PGFDPEISKL  300
301   AQRVLINPRK  IDYHTGVFAS  KITPARDGKP  VLIELIDAKT  KEPKDTLEVD  AALIATGRAP  360
361   FTNGLGLENV  NVVTQRGFIP  VDERMRVIDG  KGTLVPNLYC  IGDANGKLML  AHAASAQGIS  420
421   VVEQVSGRDH  VLNHLSIPAA  CFTHPEISMV  GLTEPQAKEK  GEKEGFKVSV  VKTSFKANTK  480
481   ALAENEGEGI  AKMIYRPDNG  EILGVHIFGL  HAADLIHEAS  NAIALGTRIQ  DIKLAVHAHP  540
541   TLSEVLDELF  KAAKVESHAT  TRTGDAKIKL  NTNQEDRKGR  RRGGDDEKQP  SVSKDLKDIS  600
601   TRPSSFFENI  SVGVLSLLSL  IFV  623
Nucleotide CDS Sequence (FASTA)
1     ATGCAATCAG  CTATGGCGCT  TTCGTTCTCC  CAGACGTCGT  TTACAAGACC  AAACCACGTG  60
61    CTCGGATCAT  CTGGTTCTGT  TTTCTCTACG  CCCAGAAGTC  TCCGGTTCTG  CGGACTCCGG  120
121   CGGGAAGCGT  TTGGTTTCTC  AACGTCGAAT  CAGTTGGCTA  TTCGCAGTAA  CCGAATCCAA  180
181   TTTCTAAGTA  GGAAGTCATT  CCAAGTCTCC  GCTTCTGCTT  CAAGTAATGG  TAATGGCGCT  240
241   CCACCGAAAT  CTTTCGATTA  CGATTTGATC  ATCATCGGAG  CTGGAGTTGG  TGGCCACGGA  300
301   GCTGCTTTGC  ACGCCGTTGA  AAAGGGACTT  AAAACAGCCA  TTATTGAAGG  AGATGTTGTT  360
361   GGAGGGACTT  GTGTTAACAG  AGGATGTGTG  CCTTCTAAAG  CTCTTCTTGC  TGTTAGTGGT  420
421   CGAATGCGGG  AACTTCAGAA  CGAACATCAC  ATGAAGTCCT  TTGGTCTCCA  GGTTTCAGCT  480
481   GCTGGATATG  ATCGTCAGGG  TGTGGCAGAT  CATGCTAATA  ATCTGGCTAC  CAAAATACGA  540
541   AACAATCTGA  CCAATTCAAT  GAAGGCAATT  GGTGTTGACA  TATTGACTGG  ATTTGGCAGT  600
601   GTTCTGGGTC  CACAAAAGGT  TAAATATGGG  AAGGACAATA  TTATTACTGC  AAAAGATATA  660
661   ATCATTGCCA  CTGGATCTGT  GCCGTTTGTC  CCTAAAGGAA  TTGAAGTTGA  TGGAAAGACT  720
721   GTGATCACCA  GTGACCATGC  TTTGAAATTA  GAGTCTGTCC  CTGAGTGGAT  TGCAATTGTA  780
781   GGAAGTGGTT  ATATTGGTCT  TGAGTTCAGT  GATGTTTACA  CAGCTCTTGG  AAGTGAGGTA  840
841   ACTTTTATAG  AAGCACTGGA  TCAGCTAATG  CCTGGATTTG  ATCCTGAGAT  CAGTAAGCTA  900
901   GCTCAGAGGG  TTTTGATAAA  TCCAAGAAAG  ATTGACTATC  ATACTGGAGT  CTTTGCAAGC  960
961   AAAATTACTC  CGGCAAGGGA  TGGGAAACCA  GTTCTGATTG  AGCTTATTGA  TGCCAAAACC  1020
1021  AAGGAACCTA  AGGATACTTT  GGAGGTAGAT  GCTGCTCTTA  TTGCTACTGG  GAGAGCTCCA  1080
1081  TTCACCAATG  GACTTGGCTT  GGAAAATGTC  AATGTTGTGA  CGCAGAGAGG  TTTCATACCA  1140
1141  GTTGATGAGC  GAATGCGTGT  GATCGATGGA  AAGGGGACTC  TGGTTCCGAA  CTTGTACTGC  1200
1201  ATTGGTGATG  CCAATGGTAA  ATTGATGCTT  GCACATGCAG  CCAGTGCCCA  AGGAATTTCT  1260
1261  GTGGTCGAGC  AAGTCAGCGG  CAGAGATCAT  GTGCTTAATC  ATCTTAGCAT  CCCAGCTGCT  1320
1321  TGCTTTACTC  ATCCTGAAAT  CAGCATGGTG  GGATTAACAG  AGCCTCAAGC  AAAAGAAAAA  1380
1381  GGCGAGAAGG  AAGGATTTAA  AGTTAGTGTT  GTCAAGACAA  GTTTCAAGGC  TAACACAAAG  1440
1441  GCCCTAGCTG  AAAATGAAGG  AGAAGGAATA  GCTAAGATGA  TATACCGACC  TGACAATGGT  1500
1501  GAAATCTTAG  GAGTTCATAT  ATTTGGACTG  CATGCAGCTG  ACCTTATCCA  TGAAGCTTCT  1560
1561  AATGCGATTG  CTCTAGGAAC  GCGTATTCAG  GACATAAAAT  TGGCAGTTCA  TGCACATCCA  1620
1621  ACACTCTCTG  AGGTCCTCGA  CGAACTGTTC  AAAGCAGCCA  AGGTTGAAAG  TCATGCTACG  1680
1681  ACAAGGACAG  GAGATGCAAA  GATAAAGCTA  AACACGAACC  AGGAAGATCG  AAAAGGAAGA  1740
1741  AGAAGAGGAG  GAGATGATGA  GAAACAACCT  TCCGTAAGTA  AAGACTTGAA  AGATATATCT  1800
1801  ACAAGGCCTT  CTTCTTTCTT  TGAGAATATT  TCTGTTGGAG  TCTTGTCTCT  GCTTTCACTT  1860
1861  ATATTTGTTT  AA  1872

▼ KEYWORD

ID
Family
Alternative splicing
Chloroplast
Complete proteome
Disulfide bond
FAD
Flavoprotein
NAD
Oxidoreductase
Plastid
Redox-active center
Reference proteome
Transit peptide

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Chloroplast envelope
Cellular Component
Chloroplast stroma
Cellular Component
Nucleolus
Molecular Function
Dihydrolipoyl dehydrogenase activity
Molecular Function
Flavin adenine dinucleotide binding
Biological Process
Acetyl-CoA biosynthetic process from pyruvate
Biological Process
Cell redox homeostasis
Biological Process
Response to arsenic-containing substance

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
AAindex
Function
CGDB
Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0113Arabidopsis lyrata96.120.01117
LLPS-Brn-2148Brassica napus88.920.01045
LLPS-Bro-1026Brassica oleracea88.760.01043
LLPS-Brr-0867Brassica rapa88.60.01033
LLPS-Hov-1572Hordeum vulgare88.40.0 827
LLPS-Orb-1274Oryza barthii88.40.0 828
LLPS-Orbr-1805Oryza brachyantha88.330.0 838
LLPS-Glm-2751Glycine max86.520.0 895
LLPS-Cus-1283Cucumis sativus86.250.0 894
LLPS-Phv-1405Phaseolus vulgaris86.170.0 889
LLPS-Vir-0760Vigna radiata85.960.0 893
LLPS-Thc-2177Theobroma cacao85.230.0 910
LLPS-Hea-2482Helianthus annuus85.10.0 884
LLPS-Sem-1005Selaginella moellendorffii84.520.0 813
LLPS-Nia-2486Nicotiana attenuata84.440.0 893
LLPS-Php-1860Physcomitrella patens84.230.0 810
LLPS-Dac-1023Daucus carota84.070.0 881
LLPS-Gor-1384Gossypium raimondii83.660.0 906
LLPS-Mae-2468Manihot esculenta83.250.0 904
LLPS-Via-0097Vigna angularis82.920.0 903
LLPS-Orr-1653Oryza rufipogon82.860.0 847
LLPS-Orm-0673Oryza meridionalis82.860.0 847
LLPS-Ors-0155Oryza sativa82.860.0 847
LLPS-Ori-1052Oryza indica82.860.0 846
LLPS-Orni-0737Oryza nivara82.860.0 847
LLPS-Prp-1391Prunus persica82.740.0 890
LLPS-Met-1928Medicago truncatula82.620.0 891
LLPS-Orgl-0664Oryza glumaepatula82.610.0 833
LLPS-Sob-0815Sorghum bicolor82.580.0 849
LLPS-Org-1895Oryza glaberrima82.330.0 835
LLPS-Orp-0992Oryza punctata82.180.0 838
LLPS-Tra-2648Triticum aestivum82.080.0 838
LLPS-Lep-1667Leersia perrieri81.950.0 838
LLPS-Zem-2393Zea mays81.510.0 836
LLPS-Tru-0119Triticum urartu81.390.0 807
LLPS-Brd-0254Brachypodium distachyon80.580.0 861
LLPS-Sei-0544Setaria italica80.250.0 849
LLPS-Pot-0370Populus trichocarpa80.170.0 880
LLPS-Mua-0767Musa acuminata79.280.0 810
LLPS-Amt-0962Amborella trichopoda78.450.0 840
LLPS-Sol-0042Solanum lycopersicum77.970.0 866
LLPS-Osl-0177Ostreococcus lucimarinus65.20.0 613
LLPS-Chc-1096Chondrus crispus61.490.0 620
LLPS-Spr-1002Sporisorium reilianum38.418e-71 244
LLPS-Abg-0728Absidia glauca38.331e-74 254
LLPS-Usm-0472Ustilago maydis38.199e-70 241
LLPS-Sot-0560Solanum tuberosum37.721e-75 256
LLPS-Scc-0112Schizosaccharomyces cryophilus37.671e-70 243
LLPS-Pug-0871Puccinia graminis37.554e-68 236
LLPS-Put-0732Puccinia triticina37.183e-64 226
LLPS-Mao-1400Magnaporthe oryzae36.997e-70 241
LLPS-Aso-0519Aspergillus oryzae36.872e-69 240
LLPS-Asf-0143Aspergillus flavus36.872e-69 240
LLPS-Viv-1307Vitis vinifera36.57e-73 249
LLPS-Asc-1346Aspergillus clavatus36.52e-68 237
LLPS-Coc-2076Corchorus capsularis36.472e-72 248
LLPS-Yal-1290Yarrowia lipolytica36.448e-64 224
LLPS-Scs-0420Sclerotinia sclerotiorum36.343e-66 232
LLPS-Coo-0189Colletotrichum orbiculare36.344e-66 231
LLPS-Drm-0975Drosophila melanogaster36.326e-75 254
LLPS-Nec-0746Neurospora crassa36.294e-68 236
LLPS-Map-0548Magnaporthe poae36.291e-71 246
LLPS-Ast-0991Aspergillus terreus36.282e-69 240
LLPS-Asni-0138Aspergillus niger36.282e-63 224
LLPS-Scj-0486Schizosaccharomyces japonicus36.251e-67 235
LLPS-Kop-0455Komagataella pastoris36.223e-55 201
LLPS-Cym-1046Cyanidioschyzon merolae36.182e-68 238
LLPS-Gag-0273Gaeumannomyces graminis36.078e-72 246
LLPS-Cogr-1336Colletotrichum graminicola36.065e-69 239
LLPS-Cog-0956Colletotrichum gloeosporioides35.986e-65 237
LLPS-Tum-1453Tuber melanosporum35.851e-66 233
LLPS-Otg-1942Otolemur garnettii35.745e-51 188
LLPS-Scp-1094Schizosaccharomyces pombe35.676e-67 233
LLPS-Asfu-0931Aspergillus fumigatus35.621e-66 233
LLPS-Nef-0811Neosartorya fischeri35.623e-66 232
LLPS-Scf-1894Scleropages formosus35.64e-71 244
LLPS-Mel-1369Melampsora laricipopulina35.596e-56 203
LLPS-Cae-1104Caenorhabditis elegans35.562e-70 243
LLPS-Beb-0569Beauveria bassiana35.483e-66 231
LLPS-Dar-4067Danio rerio35.462e-68 237
LLPS-Icp-0801Ictalurus punctatus35.464e-71 244
LLPS-Ved-0004Verticillium dahliae35.423e-70 242
LLPS-Chr-0497Chlamydomonas reinhardtii35.351e-75 256
LLPS-Fus-0842Fusarium solani35.331e-65 229
LLPS-Fuo-0113Fusarium oxysporum35.212e-67 234
LLPS-Ten-2995Tetraodon nigroviridis35.161e-67 235
LLPS-Crn-0304Cryptococcus neoformans35.131e-63 224
LLPS-Tut-1772Tursiops truncatus35.097e-67 233
LLPS-Sus-2732Sus scrofa35.098e-67 233
LLPS-Scm-3496Scophthalmus maximus35.021e-68 238
LLPS-Fuv-0782Fusarium verticillioides34.993e-67 234
LLPS-Blg-0078Blumeria graminis34.962e-61 218
LLPS-Cap-0489Cavia porcellus34.957e-68 236
LLPS-Asm-3109Astyanax mexicanus34.956e-68 236
LLPS-Zyt-0334Zymoseptoria tritici34.886e-63 223
LLPS-Orl-1147Oryzias latipes34.871e-66 233
LLPS-Ova-0370Ovis aries34.737e-68 236
LLPS-Mea-0286Mesocricetus auratus34.736e-68 236
LLPS-Leo-0836Lepisosteus oculatus34.722e-69 241
LLPS-Dos-0596Dothistroma septosporum34.662e-63 224
LLPS-Cis-1131Ciona savignyi34.651e-57 208
LLPS-Miv-0544Microbotryum violaceum34.592e-59 212
LLPS-Orn-0446Oreochromis niloticus34.582e-68 237
LLPS-Gaa-0469Gasterosteus aculeatus34.582e-67 235
LLPS-Tar-0840Takifugu rubripes34.511e-64 227
LLPS-Xim-2565Xiphophorus maculatus34.513e-67 234
LLPS-Bot-1107Bos taurus34.516e-68 236
LLPS-Dio-3724Dipodomys ordii34.512e-67 234
LLPS-Ere-0711Erinaceus europaeus34.514e-67 234
LLPS-Fud-0498Fukomys damarensis34.511e-67 235
LLPS-Hos-1903Homo sapiens34.294e-66 231
LLPS-Pat-1838Pan troglodytes34.297e-66 231
LLPS-Tag-2419Taeniopygia guttata34.282e-66 231
LLPS-Loa-1805Loxodonta africana34.284e-66 231
LLPS-Trr-1019Trichoderma reesei34.276e-64 223
LLPS-Sah-0889Sarcophilus harrisii34.145e-67 234
LLPS-Eqc-2563Equus caballus34.072e-66 232
LLPS-Poa-1715Pongo abelii34.078e-66 230
LLPS-Nol-2456Nomascus leucogenys34.071e-65 230
LLPS-Fec-1080Felis catus34.074e-66 231
LLPS-Pap-2495Pan paniscus34.071e-65 231
LLPS-Pof-1399Poecilia formosa34.071e-65 230
LLPS-Gog-2219Gorilla gorilla34.071e-65 230
LLPS-Asg-0550Ashbya gossypii34.065e-59 211
LLPS-Trv-0049Trichoderma virens34.01e-63 224
LLPS-Mod-3672Monodelphis domestica33.921e-64 227
LLPS-Mam-4547Macaca mulatta33.851e-65 230
LLPS-Ict-3515Ictidomys tridecemlineatus33.859e-67 233
LLPS-Man-1491Macaca nemestrina33.852e-65 229
LLPS-Ran-2444Rattus norvegicus33.855e-65 228
LLPS-Myl-2574Myotis lucifugus33.859e-66 229
LLPS-Aim-2998Ailuropoda melanoleuca33.856e-66 231
LLPS-Mup-2956Mustela putorius furo33.857e-66 230
LLPS-Paa-4135Papio anubis33.851e-65 229
LLPS-Mal-0096Mandrillus leucophaeus33.851e-65 230
LLPS-Chs-1548Chlorocebus sabaeus33.852e-65 230
LLPS-Maf-2355Macaca fascicularis33.851e-65 230
LLPS-Cea-2787Cercocebus atys33.852e-65 230
LLPS-Caj-1031Callithrix jacchus33.851e-65 230
LLPS-Phn-0781Phaeosphaeria nodorum33.772e-59 213
LLPS-Caf-2653Canis familiaris33.72e-66 232
LLPS-Xet-1040Xenopus tropicalis33.633e-66 231
LLPS-Cii-0236Ciona intestinalis33.624e-57 206
LLPS-Pytr-0386Pyrenophora triticirepentis33.552e-59 213
LLPS-Pyt-0285Pyrenophora teres33.552e-59 213
LLPS-Pes-2135Pelodiscus sinensis33.412e-67 234
LLPS-Mum-4029Mus musculus33.413e-65 229
LLPS-Lem-1312Leptosphaeria maculans33.335e-55 208
LLPS-Orc-0714Oryctolagus cuniculus33.263e-60 215
LLPS-Ora-0512Ornithorhynchus anatinus33.117e-63 221
LLPS-Aon-4183Aotus nancymaae33.093e-54 199
LLPS-Gaga-1251Gallus gallus33.044e-67 234
LLPS-Anp-1898Anas platyrhynchos33.042e-66 232
LLPS-Fia-1484Ficedula albicollis33.044e-65 228
LLPS-Rhb-0257Rhinopithecus bieti32.893e-62 220
LLPS-Meg-1533Meleagris gallopavo32.821e-66 232
LLPS-Cas-2022Carlito syrichta32.756e-62 220
LLPS-Anc-3366Anolis carolinensis32.576e-59 211
LLPS-Sac-1059Saccharomyces cerevisiae32.43e-55 201
LLPS-Gas-1372Galdieria sulphuraria32.094e-54 198
LLPS-Urm-0892Ursus maritimus30.775e-51 189