DrLLPS - Data resource of LLPS

LLPS-Art-0761
NRPB10

▼ OVERVIEW


Status:	Reviewed
Protein Name:	DNA-directed RNA polymerases II, IV and V subunit 10; DNA-directed RNA Polymerase II subunit L
Gene Name:	NRPB10, NRPD10, NRPE10, At1g11475, T23J18.30
Ensembl Gene:	AT1G11475
Ensembl Protein:	AT1G11475.1
Organism:	Arabidopsis thaliana
Taxa ID:	3702
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Description	Tissue/Cell	PMIDs
Nucleolus	"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."	Arabidopsis thaliana cells	26980300

▼ FUNCTION

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	AT1G11475.1	AT1G11475.1
UniProt		Q8LFJ6, NRPBA_ARATH
GeneBank	AK228397, AC011661, AY084808, BT025306, CP002684, AK118363	, AAM61374.1, BAF00334.1, AEE28741.1, ABF47122.1, BAC42977.1
RefSeq	NM_179309.3	NP_849640.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MIIPVRCFTC GKVIGNKWDQ YLDLLQLDYT EGDALDALQL VRYCCRRMLM THVDLIEKLL 60 61 NYNTLEKSDN S 71
Nucleotide CDS Sequence (FASTA)
1 ATGATCATCC CTGTTCGTTG CTTTACTTGT GGAAAGGTGA TTGGAAACAA ATGGGATCAG 60 61 TATCTTGATC TTCTCCAGCT CGACTACACT GAAGGGGACG CACTTGATGC ACTCCAGCTA 120 121 GTCAGATACT GCTGCAGGCG TATGCTAATG ACTCATGTTG ATCTGATTGA GAAGCTTCTC 180 181 AACTACAACA CTCTGGAGAA ATCAGACAAC AGTTAG 216

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0240	DNA-directed RNA polymerase
KW-0479	Metal-binding
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0804	Transcription
KW-0862	Zinc

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005736	Cellular Component	RNA polymerase I complex
GO:0005665	Cellular Component	RNA polymerase II, core complex
GO:0005666	Cellular Component	RNA polymerase III complex
GO:0000418	Cellular Component	RNA polymerase IV complex
GO:0000419	Cellular Component	RNA polymerase V complex
GO:0003677	Molecular Function	DNA binding
GO:0003899	Molecular Function	DNA-directed 5'-3' RNA polymerase activity
GO:0008270	Molecular Function	Zinc ion binding
GO:0006360	Biological Process	Transcription by RNA polymerase I
GO:0006366	Biological Process	Transcription by RNA polymerase II
GO:0006383	Biological Process	Transcription by RNA polymerase III

▼ KEGG

ath:AT1G11475

▼ ANNOTATION

Disorder
IUPred2A

Domain
SMART	Pfam	InterPro	LCR-eXXXplorer	CDD
PROSITE	Gene3D

Interaction
HINT	Mentha	PINA	iRefIndex

Physicochemical
AAindex

Localization
COMPARTMENTS

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Arl-1672	Arabidopsis lyrata	100.0	3e-36	123
LLPS-Bro-2939	Brassica oleracea	97.18	2e-35	120
LLPS-Brr-2058	Brassica rapa	97.18	2e-35	120
LLPS-Brn-1029	Brassica napus	97.18	2e-35	120
LLPS-Prp-1614	Prunus persica	94.37	1e-34	118
LLPS-Hea-2581	Helianthus annuus	94.37	2e-34	118
LLPS-Orbr-1436	Oryza brachyantha	94.2	4e-33	115
LLPS-Coc-0511	Corchorus capsularis	92.96	7e-34	116
LLPS-Gor-1039	Gossypium raimondii	92.96	7e-34	116
LLPS-Viv-1018	Vitis vinifera	92.96	7e-34	116
LLPS-Pot-1504	Populus trichocarpa	92.96	9e-34	116
LLPS-Sei-0221	Setaria italica	92.96	3e-34	117
LLPS-Thc-0223	Theobroma cacao	92.96	5e-34	118
LLPS-Mua-1532	Musa acuminata	92.86	2e-33	115
LLPS-Glm-1586	Glycine max	92.75	1e-32	114
LLPS-Sot-1109	Solanum tuberosum	92.19	2e-29	105
LLPS-Tru-0305	Triticum urartu	91.55	3e-33	115
LLPS-Amt-1317	Amborella trichopoda	91.55	4e-33	114
LLPS-Tra-1204	Triticum aestivum	91.55	3e-33	115
LLPS-Cus-1601	Cucumis sativus	91.55	2e-33	115
LLPS-Sol-0213	Solanum lycopersicum	91.55	3e-33	115
LLPS-Dac-0736	Daucus carota	91.55	5e-33	114
LLPS-Zem-0120	Zea mays	90.62	3e-28	105
LLPS-Orm-0905	Oryza meridionalis	90.14	8e-33	114
LLPS-Orr-0045	Oryza rufipogon	90.14	8e-33	114
LLPS-Org-1987	Oryza glaberrima	90.14	7e-33	114
LLPS-Ors-0245	Oryza sativa	90.14	4e-33	115
LLPS-Orp-0028	Oryza punctata	90.14	6e-33	114
LLPS-Phv-1565	Phaseolus vulgaris	90.14	1e-32	113
LLPS-Mae-0208	Manihot esculenta	90.14	5e-33	114
LLPS-Orgl-1741	Oryza glumaepatula	90.14	7e-33	114
LLPS-Via-1368	Vigna angularis	90.14	8e-33	114
LLPS-Lep-0047	Leersia perrieri	90.14	7e-33	114
LLPS-Brd-0682	Brachypodium distachyon	90.14	1e-32	113
LLPS-Vir-1010	Vigna radiata	90.14	1e-32	113
LLPS-Orb-0670	Oryza barthii	90.14	8e-33	114
LLPS-Orni-1296	Oryza nivara	90.14	8e-33	114
LLPS-Met-0713	Medicago truncatula	89.86	4e-32	112
LLPS-Sem-1728	Selaginella moellendorffii	89.06	2e-27	100
LLPS-Sob-0178	Sorghum bicolor	88.73	8e-33	114
LLPS-Php-1300	Physcomitrella patens	88.73	7e-33	114
LLPS-Hov-0632	Hordeum vulgare	88.33	2e-23	91.3
LLPS-Ova-0570	Ovis aries	82.86	4e-12	60.1
LLPS-Xet-2032	Xenopus tropicalis	82.09	1e-28	103
LLPS-Lac-1104	Latimeria chalumnae	82.09	1e-28	103
LLPS-Drm-1306	Drosophila melanogaster	82.09	4e-28	102
LLPS-Osl-0681	Ostreococcus lucimarinus	81.69	1e-27	100
LLPS-Abg-1015	Absidia glauca	80.88	3e-28	102
LLPS-Eqc-0902	Equus caballus	80.6	3e-28	102
LLPS-Cap-0747	Cavia porcellus	80.6	3e-28	102
LLPS-Gaga-1555	Gallus gallus	80.6	3e-28	102
LLPS-Anc-0600	Anolis carolinensis	80.6	3e-28	102
LLPS-Nol-1803	Nomascus leucogenys	80.6	3e-28	102
LLPS-Scm-3070	Scophthalmus maximus	80.6	2e-28	102
LLPS-Fec-2128	Felis catus	80.6	3e-28	102
LLPS-Pat-3206	Pan troglodytes	80.6	3e-28	102
LLPS-Pof-1952	Poecilia formosa	80.6	2e-28	102
LLPS-Dar-3649	Danio rerio	80.6	2e-28	102
LLPS-Meg-1041	Meleagris gallopavo	80.6	3e-28	102
LLPS-Hos-0392	Homo sapiens	80.6	3e-28	102
LLPS-Anp-3069	Anas platyrhynchos	80.6	3e-28	102
LLPS-Man-2272	Macaca nemestrina	80.6	3e-28	102
LLPS-Pes-1487	Pelodiscus sinensis	80.6	3e-28	102
LLPS-Otg-2368	Otolemur garnettii	80.6	3e-28	102
LLPS-Rhb-1556	Rhinopithecus bieti	80.6	3e-28	102
LLPS-Fia-0808	Ficedula albicollis	80.6	3e-28	102
LLPS-Tut-0709	Tursiops truncatus	80.6	8e-25	93.6
LLPS-Xim-1095	Xiphophorus maculatus	80.6	2e-28	102
LLPS-Bot-2573	Bos taurus	80.6	3e-28	102
LLPS-Ran-0754	Rattus norvegicus	80.6	4e-28	107
LLPS-Paa-2640	Papio anubis	80.6	3e-28	102
LLPS-Chs-4342	Chlorocebus sabaeus	80.6	3e-28	102
LLPS-Mea-0219	Mesocricetus auratus	80.6	3e-28	102
LLPS-Maf-0450	Macaca fascicularis	80.6	3e-28	102
LLPS-Mum-3392	Mus musculus	80.6	3e-28	102
LLPS-Cis-1293	Ciona savignyi	80.6	7e-28	101
LLPS-Cea-0434	Cercocebus atys	80.6	3e-28	102
LLPS-Aon-1210	Aotus nancymaae	80.6	3e-28	102
LLPS-Sus-1220	Sus scrofa	80.6	3e-28	102
LLPS-Orl-1218	Oryzias latipes	80.6	2e-28	102
LLPS-Gog-2837	Gorilla gorilla	80.6	3e-28	102
LLPS-Caj-3722	Callithrix jacchus	80.6	3e-28	102
LLPS-Asm-2052	Astyanax mexicanus	80.6	2e-28	102
LLPS-Fud-1693	Fukomys damarensis	80.6	3e-28	102
LLPS-Chr-1680	Chlamydomonas reinhardtii	80.28	5e-29	104
LLPS-Tar-1705	Takifugu rubripes	79.1	3e-28	102
LLPS-Myl-0455	Myotis lucifugus	79.1	2e-27	100
LLPS-Icp-2633	Ictalurus punctatus	79.1	3e-28	102
LLPS-Scf-2629	Scleropages formosus	77.61	5e-28	101
LLPS-Cae-1413	Caenorhabditis elegans	77.61	2e-27	100
LLPS-Poa-1390	Pongo abelii	76.12	6e-27	99.0
LLPS-Cym-0427	Cyanidioschyzon merolae	75.81	1e-21	86.3
LLPS-Scj-0893	Schizosaccharomyces japonicus	75.71	2e-25	95.5
LLPS-Scp-1376	Schizosaccharomyces pombe	74.29	2e-25	95.5
LLPS-Scc-0296	Schizosaccharomyces cryophilus	74.29	2e-25	95.5
LLPS-Yal-1254	Yarrowia lipolytica	73.53	4e-27	100
LLPS-Miv-0232	Microbotryum violaceum	73.13	1e-26	98.2
LLPS-Mel-0280	Melampsora laricipopulina	72.86	2e-26	97.8
LLPS-Scs-0458	Sclerotinia sclerotiorum	72.73	1e-09	55.5
LLPS-Kop-0444	Komagataella pastoris	72.46	8e-27	99.0
LLPS-Gas-0921	Galdieria sulphuraria	72.06	2e-21	84.7
LLPS-Chc-0165	Chondrus crispus	71.88	6e-27	101
LLPS-Crn-0525	Cryptococcus neoformans	71.64	3e-24	92.0
LLPS-Usm-0486	Ustilago maydis	70.15	5e-24	91.7
LLPS-Spr-0557	Sporisorium reilianum	70.15	3e-24	92.0
LLPS-Tag-2108	Taeniopygia guttata	70.15	2e-26	97.8
LLPS-Gag-0677	Gaeumannomyces graminis	68.75	2e-21	85.5
LLPS-Map-0550	Magnaporthe poae	68.75	1e-21	85.5
LLPS-Cogr-1122	Colletotrichum graminicola	68.25	1e-21	85.5
LLPS-Cog-0830	Colletotrichum gloeosporioides	68.25	1e-21	85.5
LLPS-Asfu-0521	Aspergillus fumigatus	67.74	6e-20	82.8
LLPS-Ved-0818	Verticillium dahliae	67.74	5e-21	84.0
LLPS-Nec-0213	Neurospora crassa	67.19	1e-20	83.2
LLPS-Sac-0385	Saccharomyces cerevisiae	67.14	3e-22	87.0
LLPS-Tum-1305	Tuber melanosporum	66.18	3e-23	89.4
LLPS-Trv-0372	Trichoderma virens	65.62	3e-20	82.0
LLPS-Trr-1068	Trichoderma reesei	65.62	3e-20	82.0
LLPS-Phn-0337	Phaeosphaeria nodorum	64.71	2e-24	92.4
LLPS-Nef-1074	Neosartorya fischeri	64.71	2e-22	87.8
LLPS-Blg-1069	Blumeria graminis	64.71	3e-23	89.7
LLPS-Asc-0914	Aspergillus clavatus	64.71	2e-22	87.8
LLPS-Asn-0523	Aspergillus nidulans	64.71	3e-22	87.0
LLPS-Pyt-0955	Pyrenophora teres	64.52	8e-21	84.0
LLPS-Asg-0120	Ashbya gossypii	64.29	2e-22	87.4
LLPS-Cas-2957	Carlito syrichta	62.69	6e-20	80.5
LLPS-Coo-0925	Colletotrichum orbiculare	62.5	2e-20	82.8
LLPS-Pytr-0963	Pyrenophora triticirepentis	61.76	1e-22	88.2
LLPS-Pug-0794	Puccinia graminis	61.76	3e-22	87.0
LLPS-Beb-0845	Beauveria bassiana	61.43	2e-20	82.8
LLPS-Mao-0483	Magnaporthe oryzae	60.0	2e-22	87.8
LLPS-Fuo-0927	Fusarium oxysporum	59.72	1e-20	83.2
LLPS-Fuv-1178	Fusarium verticillioides	59.72	1e-20	83.2
LLPS-Ict-1554	Ictidomys tridecemlineatus	59.7	1e-14	67.4
LLPS-Ere-0653	Erinaceus europaeus	59.7	2e-16	71.6
LLPS-Nia-0671	Nicotiana attenuata	59.55	3e-26	97.8
LLPS-Lem-0061	Leptosphaeria maculans	59.42	9e-22	85.9
LLPS-Ori-0878	Oryza indica	56.64	1e-24	94.4
LLPS-Mal-3230	Mandrillus leucophaeus	54.93	1e-10	56.6
LLPS-Zyt-0311	Zymoseptoria tritici	53.42	1e-19	80.9
LLPS-Dos-1243	Dothistroma septosporum	51.35	6e-19	78.6
LLPS-Urm-2960	Ursus maritimus	46.38	1e-08	51.6

LLPS-Art-0761NRPB10

Protein Sequence

Nucleotide Sequence

LLPS-Art-0761
NRPB10