LLPS-Art-0749
TOC34
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Translocase of chloroplast 34, chloroplastic |
| Gene Name: | TOC34, OEP34, PPI3, At5g05000, MUG13.14 |
| Ensembl Gene: | AT5G05000 |
| Ensembl Protein: | AT5G05000.2 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
▼ FUNCTION
| GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT5G05000.2 | AT5G05000.2 |
| Ensembl | AT5G05000.3 | AT5G05000.3 |
| Ensembl | AT5G05000.1 | AT5G05000.1 |
| UniProt | Q38906, TOC34_ARATH, Q0WNL4, Q8L9G5, Q9FF74, Q9GDD2 | |
| GeneBank | AK229425, CP002688, U43377, AJ132696, AB005245, AY088447 | AAM65983.1, AED90815.1, AAD09203.1, AED90814.1, CAC17699.1, BAB11522.1, BAF01285.1, AED90816.1 |
| RefSeq | NM_120582.5, NM_180437.2, NM_203003.3 | NP_196119.1, NP_850768.1, NP_974732.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAALQTLREW IGIQQFPPAT QSKLLEILGK YKEEDVSSLT VLVMGKGGVG KSSTVNSVIG 60 61 EKAAAVSTFQ SEGLRPTLVS RTRSGFTLNI IDTPGLIEGG YVNDQAINII KRFLLNMTID 120 121 VLLYVDRLDV YRVDDLDRQV VGAITDAFGK EIWKKSALVL THAQFSPPDG LNYNHFVSKR 180 181 SNALLKVIQT GAQLKKQDLQ GFSIPVILVE NSGRCHKNES DEKILPCGTS WIPNLFNKIT 240 241 EISFNGNKAI HVDKKLVEGP NPNERGKKLI PLMFAFQYLL VMKPLVRAIK SDVSRESKPA 300 301 WELRDSGLAS RRS 313 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCAGCTT TGCAAACGCT TCGTGAATGG ATCGGTATCC AGCAGTTCCC ACCTGCTACT 60 61 CAATCTAAAT TGCTCGAGAT CCTTGGGAAG TATAAAGAAG AGGATGTGAG CTCGCTAACG 120 121 GTCCTTGTAA TGGGGAAAGG TGGTGTTGGA AAGTCATCAA CTGTGAATTC AGTTATAGGC 180 181 GAGAAAGCTG CTGCAGTTAG TACTTTCCAG TCTGAAGGAC TGAGGCCTAC CTTGGTCTCT 240 241 CGCACAAGAT CGGGATTTAC ATTGAATATC ATCGACACTC CTGGTCTTAT TGAGGGAGGA 300 301 TATGTGAATG ATCAAGCCAT CAACATTATA AAACGATTTC TCCTCAACAT GACTATAGAT 360 361 GTGCTACTAT ACGTAGACCG TTTGGATGTG TACCGGGTGG ATGACCTTGA TAGGCAAGTT 420 421 GTCGGTGCTA TAACTGATGC ATTTGGTAAA GAGATATGGA AGAAGTCTGC TCTTGTTCTC 480 481 ACCCATGCTC AGTTCTCTCC ACCAGACGGG TTAAATTATA ACCACTTTGT CTCCAAAAGA 540 541 TCTAATGCTC TTCTAAAAGT TATCCAGACA GGCGCTCAAC TGAAGAAACA GGATTTGCAG 600 601 GGTTTTTCTA TTCCTGTCAT TCTTGTTGAG AACAGCGGAA GATGCCATAA GAACGAAAGC 660 661 GATGAAAAGA TTCTTCCATG CGGGACTAGT TGGATTCCCA ATCTGTTCAA CAAAATCACA 720 721 GAGATCTCTT TTAATGGCAA CAAGGCGATT CATGTTGACA AGAAACTGGT CGAAGGGCCA 780 781 AACCCAAACG AAAGAGGAAA AAAACTGATT CCTTTAATGT TTGCATTCCA ATACTTGCTG 840 841 GTGATGAAGC CATTGGTTCG AGCAATCAAG TCCGATGTTT CGAGAGAGAG TAAACCGGCG 900 901 TGGGAGCTGC GAGACTCCGG TTTAGCAAGT CGAAGGTCTT GA 942 |
▼ KEYWORD
ID | Family |
Acetylation | |
Chloroplast | |
Complete proteome | |
GTP-binding | |
Hydrolase | |
Magnesium | |
Membrane | |
Metal-binding | |
Nucleotide-binding | |
Plastid | |
Plastid outer membrane | |
Protein transport | |
Receptor | |
Reference proteome | |
Transmembrane | |
Transmembrane helix | |
Transport
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Chloroplast | |
Cellular Component | Chloroplast envelope | |
Cellular Component | Chloroplast outer membrane | |
Cellular Component | Integral component of membrane | |
Cellular Component | Plastid | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | Identical protein binding | |
Molecular Function | Metal ion binding | |
Molecular Function | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | |
Biological Process | Chloroplast localization | |
Biological Process | Protein targeting to chloroplast |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Localization | ||||
| COMPARTMENTS | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-0037 | Arabidopsis lyrata | 93.93 | 0.0 | 550 |
| LLPS-Brn-2879 | Brassica napus | 89.46 | 0.0 | 529 |
| LLPS-Bro-0747 | Brassica oleracea | 89.22 | 2e-178 | 520 |
| LLPS-Brr-1170 | Brassica rapa | 85.95 | 3e-165 | 485 |
| LLPS-Viv-1759 | Vitis vinifera | 72.37 | 2e-146 | 422 |
| LLPS-Vir-0164 | Vigna radiata | 71.0 | 2e-74 | 235 |
| LLPS-Sot-0784 | Solanum tuberosum | 70.23 | 4e-135 | 393 |
| LLPS-Sol-2043 | Solanum lycopersicum | 69.23 | 5e-132 | 385 |
| LLPS-Prp-1620 | Prunus persica | 69.03 | 5e-135 | 393 |
| LLPS-Mua-1043 | Musa acuminata | 68.51 | 6e-139 | 403 |
| LLPS-Nia-1159 | Nicotiana attenuata | 67.22 | 8e-128 | 374 |
| LLPS-Hea-0696 | Helianthus annuus | 67.22 | 1e-130 | 381 |
| LLPS-Glm-2005 | Glycine max | 67.21 | 8e-137 | 397 |
| LLPS-Phv-1613 | Phaseolus vulgaris | 66.99 | 6e-130 | 380 |
| LLPS-Met-0977 | Medicago truncatula | 66.78 | 2e-128 | 377 |
| LLPS-Amt-0604 | Amborella trichopoda | 66.35 | 8e-127 | 372 |
| LLPS-Dac-0162 | Daucus carota | 65.89 | 1e-121 | 358 |
| LLPS-Cus-2032 | Cucumis sativus | 65.16 | 1e-136 | 397 |
| LLPS-Brd-1316 | Brachypodium distachyon | 64.31 | 2e-124 | 367 |
| LLPS-Tra-2138 | Triticum aestivum | 63.97 | 1e-123 | 364 |
| LLPS-Org-1788 | Oryza glaberrima | 63.49 | 9e-126 | 370 |
| LLPS-Orr-1583 | Oryza rufipogon | 63.49 | 9e-126 | 370 |
| LLPS-Orm-1513 | Oryza meridionalis | 63.49 | 9e-126 | 370 |
| LLPS-Orp-1148 | Oryza punctata | 63.49 | 2e-125 | 369 |
| LLPS-Ors-1976 | Oryza sativa | 63.49 | 9e-126 | 370 |
| LLPS-Orgl-1072 | Oryza glumaepatula | 63.49 | 1e-125 | 369 |
| LLPS-Orni-1406 | Oryza nivara | 63.49 | 9e-126 | 370 |
| LLPS-Ori-1269 | Oryza indica | 63.49 | 2e-125 | 370 |
| LLPS-Orb-1730 | Oryza barthii | 63.49 | 2e-124 | 370 |
| LLPS-Sob-1261 | Sorghum bicolor | 63.4 | 1e-126 | 372 |
| LLPS-Lep-0305 | Leersia perrieri | 62.83 | 2e-124 | 367 |
| LLPS-Orbr-0597 | Oryza brachyantha | 62.5 | 4e-124 | 366 |
| LLPS-Sei-2508 | Setaria italica | 62.42 | 5e-125 | 368 |
| LLPS-Sem-0818 | Selaginella moellendorffii | 61.28 | 4e-108 | 325 |
| LLPS-Zem-2187 | Zea mays | 61.15 | 6e-123 | 363 |
| LLPS-Via-1541 | Vigna angularis | 59.22 | 7e-103 | 310 |
| LLPS-Tru-1924 | Triticum urartu | 58.78 | 2e-97 | 296 |
| LLPS-Hov-1297 | Hordeum vulgare | 57.49 | 9e-116 | 345 |
| LLPS-Php-1965 | Physcomitrella patens | 56.86 | 4e-91 | 282 |
| LLPS-Thc-1291 | Theobroma cacao | 39.73 | 1e-23 | 106 |
| LLPS-Coc-0067 | Corchorus capsularis | 37.22 | 5e-24 | 107 |
| LLPS-Gor-2471 | Gossypium raimondii | 36.71 | 1e-22 | 103 |
| LLPS-Mae-2239 | Manihot esculenta | 34.65 | 7e-23 | 104 |
| LLPS-Pot-1274 | Populus trichocarpa | 34.22 | 5e-21 | 98.2 |
| LLPS-Osl-1448 | Ostreococcus lucimarinus | 33.97 | 1e-20 | 96.7 |
| LLPS-Chr-0975 | Chlamydomonas reinhardtii | 32.53 | 5e-24 | 104 |