LLPS-Art-0616
TOC159
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Translocase of chloroplast 159, chloroplastic |
| Gene Name: | TOC159, PPI2, TOC160, TOC86, At4g02510, T10P11.19, T14P8.24 |
| Ensembl Gene: | AT4G02510 |
| Ensembl Protein: | AT4G02510.4 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Others |
▼ PROPERTY
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
▼ FUNCTION
| GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis. Required for chloroplast biogenesis. Probably specialized in the import of nuclear encoded photosynthetic preproteins from the cytoplasm to the chloroplast. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT4G02510.4 | AT4G02510.4 |
| Ensembl | AT4G02510.3 | AT4G02510.3 |
| Ensembl | AT4G02510.1 | AT4G02510.1 |
| Ensembl | AT4G02510.2 | AT4G02510.2 |
| UniProt | O81283, TC159_ARATH, O22774, Q56W83, Q945M4 | |
| GeneBank | AK222164, AF412063, AY133653, AC002330, AF069298, AL161494, CP002687 | CAB80744.1, AEE82182.1, ANM66759.1, ANM66760.1, AAC19285.1, AAC78265.2, BAD95269.1, AAM91483.1, ANM66758.1, AAL06516.1 |
| RefSeq | NM_001340383.1, NM_001340385.1, NM_001340384.1, NM_116485.4 | NP_001319848.1, NP_001328635.1, NP_001328636.1, NP_567242.2 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MDSKSVTPEP TNPFYASSGQ SGKTYASVVA AAAAAAADKE DGGAVSSAKE LDSSSEAVSG 60 61 NSDKVGADDL SDSEKEKPNL VGDGKVSDEV DGSLKEDSTT PEATPKPEVV SGETIGVDDV 120 121 SSLSPKPEAV SDGVGVVEEN KKVKEDVEDI KDDGESKIEN GSVDVDVKQA STDGESESKV 180 181 KDVEEEDVGT KKDDEGESEL GGKVDVDDKS DNVIEEEGVE LTDKGDVIVN SSPVESVHVD 240 241 VAKPGVVVVG DAEGSEELKI NADAETLEVA NKFDQIGDDD SGEFEPVSDK AIEEVEEKFT 300 301 SESDSIADSS KLESVDTSAV EPEVVAAESG SEPKDVEKAN GLEKGMTYAE VIKAASAVAD 360 361 NGTKEEESVL GGIVDDAEEG VKLNNKGDFV VDSSAIEAVN VDVAKPGVVV VGDVEVSEVL 420 421 ETDGNIPDVH NKFDPIGQGE GGEVELESDK ATEEGGGKLV SEGDSMVDSS VVDSVDADIN 480 481 VAEPGVVVVG AAKEAVIKED DKDDEVDKTI SNIEEPDDLT AAYDGNFELA VKEISEAAKV 540 541 EPDEPKVGVE VEELPVSESL KVGSVDAEED SIPAAESQFE VRKVVEGDSA EEDENKLPVE 600 601 DIVSSREFSF GGKEVDQEPS GEGVTRVDGS ESEEETEEMI FGSSEAAKQF LAELEKASSG 660 661 IEAHSDEANI SNNMSDRIDG QIVTDSDEDV DTEDEGEEKM FDTAALAALL KAATGGGSSE 720 721 GGNFTITSQD GTKLFSMDRP AGLSSSLRPL KPAAAPRANR SNIFSNSNVT MADETEINLS 780 781 EEEKQKLEKL QSLRVKFLRL LQRLGHSAED SIAAQVLYRL ALLAGRQAGQ LFSLDAAKKK 840 841 AVESEAEGNE ELIFSLNILV LGKAGVGKSA TINSILGNQI ASIDAFGLST TSVREISGTV 900 901 NGVKITFIDT PGLKSAAMDQ STNAKMLSSV KKVMKKCPPD IVLYVDRLDT QTRDLNNLPL 960 961 LRTITASLGT SIWKNAIVTL THAASAPPDG PSGTPLSYDV FVAQCSHIVQ QSIGQAVGDL 1020 1021 RLMNPSLMNP VSLVENHPLC RKNREGVKVL PNGQTWRSQL LLLCYSLKVL SETNSLLRPQ 1080 1081 EPLDHRKVFG FRVRSPPLPY LLSWLLQSRA HPKLPGDQGG DSVDSDIEID DVSDSEQEDG 1140 1141 EDDEYDQLPP FKPLRKTQLA KLSNEQRKAY FEEYDYRVKL LQKKQWREEL KRMKEMKKNG 1200 1201 KKLGESEFGY PGEEDDPENG APAAVPVPLP DMVLPPSFDS DNSAYRYRYL EPTSQLLTRP 1260 1261 VLDTHGWDHD CGYDGVNAEH SLALASRFPA TATVQVTKDK KEFNIHLDSS VSAKHGENGS 1320 1321 TMAGFDIQNV GKQLAYVVRG ETKFKNLRKN KTTVGGSVTF LGENIATGVK LEDQIALGKR 1380 1381 LVLVGSTGTM RSQGDSAYGA NLEVRLREAD FPIGQDQSSF GLSLVKWRGD LALGANLQSQ 1440 1441 VSVGRNSKIA LRAGLNNKMS GQITVRTSSS DQLQIALTAI LPIAMSIYKS IRPEATNDKY 1500 1501 SMY 1503 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGACTCAA AGTCGGTTAC TCCAGAACCA ACCAACCCCT TCTACGCTTC TTCGGGGCAA 60 61 TCAGGAAAAA CCTATGCTTC TGTTGTCGCC GCCGCTGCTG CTGCAGCCGC CGATAAGGAG 120 121 GATGGTGGTG CTGTGAGTAG TGCCAAGGAG TTGGATTCCT CATCGGAGGC TGTGTCTGGT 180 181 AATTCGGATA AGGTTGGAGC TGATGATTTA TCTGACTCCG AGAAGGAGAA GCCGAATTTG 240 241 GTGGGTGATG GGAAGGTTTC CGACGAGGTG GATGGTTCTT TAAAGGAGGA TTCTACTACT 300 301 CCTGAGGCTA CTCCGAAGCC TGAGGTGGTT TCTGGTGAGA CAATTGGTGT AGATGATGTT 360 361 TCATCGTTAT CTCCGAAGCC GGAGGCTGTT TCTGATGGTG TAGGGGTTGT GGAGGAGAAT 420 421 AAGAAGGTTA AGGAGGACGT GGAGGATATT AAAGACGATG GTGAGAGTAA GATTGAAAAT 480 481 GGGAGTGTTG ATGTTGATGT GAAACAGGCT TCCACAGATG GGGAGAGTGA GAGTAAAGTG 540 541 AAGGATGTGG AAGAAGAAGA TGTTGGAACA AAAAAAGATG ATGAGGGGGA GAGTGAGTTG 600 601 GGTGGAAAAG TTGATGTTGA CGATAAAAGT GATAATGTTA TTGAAGAAGA GGGTGTGGAG 660 661 TTAACTGATA AAGGAGACGT CATTGTGAAC TCGTCCCCTG TAGAATCAGT GCATGTTGAT 720 721 GTGGCAAAAC CAGGGGTGGT TGTTGTAGGA GACGCAGAGG GAAGTGAGGA GTTGAAGATT 780 781 AATGCTGATG CTGAAACTCT TGAAGTGGCT AATAAGTTTG ATCAAATTGG GGATGATGAT 840 841 AGTGGTGAAT TTGAACCTGT GTCTGACAAG GCCATTGAGG AGGTAGAAGA AAAATTTACT 900 901 AGCGAATCAG ACTCTATTGC AGACTCCTCT AAGTTAGAAT CTGTGGATAC CAGTGCTGTA 960 961 GAGCCAGAGG TTGTAGCTGC CGAGAGTGGG AGTGAACCAA AGGATGTGGA AAAAGCCAAC 1020 1021 GGATTGGAGA AGGGTATGAC TTATGCTGAA GTAATCAAGG CAGCTAGTGC AGTAGCTGAC 1080 1081 AATGGAACCA AAGAGGAGGA GAGTGTGCTC GGTGGCATAG TCGATGATGC AGAAGAAGGT 1140 1141 GTTAAGTTAA ACAACAAAGG AGACTTTGTG GTGGACTCAT CTGCTATTGA AGCTGTGAAT 1200 1201 GTAGATGTGG CAAAGCCAGG GGTTGTTGTT GTTGGAGACG TAGAGGTGAG TGAGGTGCTG 1260 1261 GAAACTGATG GCAACATCCC TGATGTGCAT AATAAGTTTG ATCCAATTGG CCAAGGTGAA 1320 1321 GGTGGTGAAG TTGAACTTGA ATCCGATAAA GCCACAGAGG AGGGAGGAGG AAAGTTGGTT 1380 1381 AGTGAAGGAG ACTCTATGGT TGACTCCTCT GTGGTGGACT CTGTTGATGC TGATATCAAT 1440 1441 GTTGCAGAGC CAGGGGTTGT GGTTGTCGGG GCGGCTAAGG AGGCTGTAAT TAAGGAAGAT 1500 1501 GATAAAGATG ATGAGGTTGA CAAGACCATC TCAAATATTG AGGAACCTGA TGACCTGACT 1560 1561 GCTGCATATG ATGGAAATTT TGAATTGGCT GTTAAGGAAA TATCAGAGGC TGCCAAAGTA 1620 1621 GAGCCAGACG AACCAAAAGT AGGTGTGGAA GTAGAAGAAT TGCCTGTTTC TGAAAGTTTA 1680 1681 AAAGTGGGTT CAGTTGATGC AGAAGAGGAT TCAATTCCTG CAGCTGAGTC ACAGTTTGAG 1740 1741 GTTCGGAAAG TTGTCGAAGG GGACAGTGCT GAAGAGGATG AAAACAAGCT CCCAGTCGAA 1800 1801 GACATTGTTT CTTCTCGTGA GTTTAGCTTT GGAGGCAAGG AAGTGGACCA GGAACCTTCT 1860 1861 GGCGAAGGTG TTACCAGGGT TGATGGGTCT GAAAGTGAAG AAGAAACTGA AGAGATGATA 1920 1921 TTTGGGAGTT CTGAAGCTGC AAAACAGTTC TTAGCAGAGT TGGAAAAGGC TTCTTCTGGT 1980 1981 ATAGAGGCAC ATTCTGATGA AGCAAACATT TCTAACAATA TGTCAGATAG GATTGATGGC 2040 2041 CAGATTGTCA CCGATTCTGA CGAGGATGTA GACACAGAGG ATGAAGGTGA GGAGAAAATG 2100 2101 TTTGATACTG CAGCTTTGGC TGCGCTTTTG AAGGCAGCCA CTGGTGGTGG AAGTTCAGAA 2160 2161 GGTGGCAATT TTACCATAAC ATCTCAGGAT GGCACGAAGC TTTTCTCTAT GGATCGACCT 2220 2221 GCTGGTTTGA GTTCATCGTT AAGGCCCTTG AAGCCTGCAG CAGCTCCACG TGCAAACCGT 2280 2281 TCCAACATCT TTTCCAATTC TAATGTCACA ATGGCAGATG AGACTGAGAT TAACTTGAGC 2340 2341 GAGGAAGAGA AACAGAAATT AGAAAAGTTG CAAAGCCTCC GTGTGAAGTT TTTGCGGCTT 2400 2401 TTGCAAAGGT TGGGTCATTC GGCAGAAGAT TCAATTGCAG CGCAGGTTCT TTACCGTCTT 2460 2461 GCACTACTTG CTGGGAGACA AGCAGGGCAG TTATTCAGTC TTGATGCTGC AAAGAAGAAG 2520 2521 GCTGTGGAGT CTGAGGCTGA GGGCAACGAA GAATTGATCT TCTCCCTAAA CATACTGGTC 2580 2581 CTTGGAAAAG CCGGGGTGGG AAAAAGTGCT ACTATAAATT CCATTTTGGG AAACCAGATT 2640 2641 GCGTCCATTG ATGCTTTTGG GCTCTCAACC ACTTCGGTTA GAGAAATTTC TGGAACGGTG 2700 2701 AATGGTGTCA AGATTACCTT TATTGATACT CCGGGTTTGA AGTCTGCTGC GATGGATCAA 2760 2761 AGTACAAATG CAAAAATGTT GTCCTCTGTA AAGAAGGTAA TGAAGAAGTG TCCCCCTGAT 2820 2821 ATTGTACTAT ATGTAGATCG TCTTGACACC CAGACCAGGG ACTTGAACAA TTTGCCCTTG 2880 2881 CTAAGGACGA TTACTGCTTC TCTTGGTACA TCCATATGGA AAAACGCTAT AGTGACATTG 2940 2941 ACCCATGCGG CTTCTGCCCC TCCTGATGGC CCATCTGGCA CCCCATTGAG CTATGATGTG 3000 3001 TTTGTAGCGC AGTGCTCACA TATTGTGCAA CAGTCTATAG GACAGGCTGT TGGAGATCTA 3060 3061 CGCTTGATGA ATCCAAGTCT GATGAATCCA GTTTCACTTG TTGAGAATCA CCCCTTGTGT 3120 3121 AGGAAGAACC GGGAGGGAGT GAAGGTTCTC CCGAATGGCC AAACTTGGAG ATCTCAGCTG 3180 3181 TTGCTATTGT GTTACTCCCT GAAGGTTTTG TCAGAAACAA ATTCTCTATT GAGGCCTCAA 3240 3241 GAACCATTGG ACCATCGTAA AGTATTTGGT TTCCGAGTTA GATCCCCGCC TCTCCCTTAC 3300 3301 TTGTTGTCTT GGCTGTTGCA GTCCCGTGCA CATCCTAAGC TCCCTGGAGA CCAAGGTGGT 3360 3361 GATAGTGTTG ACTCTGATAT CGAAATTGAT GATGTGTCTG ATTCTGAGCA GGAAGATGGG 3420 3421 GAAGATGATG AGTATGACCA GCTGCCACCA TTTAAGCCTC TTCGAAAAAC CCAACTTGCA 3480 3481 AAGCTCTCAA ATGAACAGAG AAAGGCATAT TTCGAGGAGT ATGATTACCG TGTAAAGCTC 3540 3541 CTGCAGAAGA AGCAATGGAG AGAGGAATTA AAGAGGATGA AAGAAATGAA GAAAAACGGG 3600 3601 AAGAAGCTGG GTGAAAGTGA GTTTGGTTAT CCGGGAGAAG AAGATGATCC AGAAAACGGG 3660 3661 GCTCCAGCTG CAGTGCCAGT TCCATTACCC GATATGGTTT TGCCACCTTC ATTTGATAGT 3720 3721 GATAACTCAG CTTACCGATA CCGATATCTG GAACCCACTT CACAACTCCT AACCAGGCCA 3780 3781 GTGTTGGATA CCCATGGTTG GGACCATGAC TGTGGATATG ACGGCGTCAA TGCAGAACAC 3840 3841 AGTCTTGCTC TAGCTAGCCG GTTCCCTGCC ACAGCTACTG TCCAAGTCAC CAAGGACAAG 3900 3901 AAAGAGTTCA ACATTCATCT GGACTCCTCT GTGTCTGCTA AGCACGGGGA GAATGGATCC 3960 3961 ACCATGGCAG GGTTCGATAT TCAGAATGTA GGCAAGCAGC TGGCATATGT GGTCAGAGGA 4020 4021 GAAACCAAAT TCAAGAATTT GAGGAAGAAC AAGACAACTG TTGGAGGGTC AGTGACATTC 4080 4081 TTGGGAGAGA ACATCGCCAC TGGGGTCAAA CTCGAGGACC AAATAGCACT GGGGAAAAGG 4140 4141 TTGGTGCTTG TGGGCAGCAC TGGGACAATG CGATCACAGG GAGATTCGGC CTATGGTGCG 4200 4201 AACCTCGAGG TCAGGCTTAG GGAAGCTGAT TTCCCAATTG GACAGGACCA ATCTTCTTTT 4260 4261 GGGCTGTCTC TGGTAAAGTG GAGAGGCGAT TTAGCCCTTG GAGCCAATCT CCAATCTCAA 4320 4321 GTCTCTGTTG GAAGGAACTC AAAGATTGCG CTTCGTGCAG GACTTAACAA CAAGATGAGC 4380 4381 GGACAGATCA CAGTCAGAAC CAGCAGCTCG GATCAGTTGC AAATCGCTCT CACAGCCATT 4440 4441 CTTCCAATTG CCATGTCCAT CTACAAGAGC ATTCGACCCG AAGCGACGAA CGACAAGTAC 4500 4501 AGCATGTACT AA 4512 |
▼ KEYWORD
ID | Family |
Chloroplast | |
Coiled coil | |
Complete proteome | |
Cytoplasm | |
GTP-binding | |
Hydrolase | |
Magnesium | |
Membrane | |
Metal-binding | |
Nucleotide-binding | |
Phosphoprotein | |
Plastid | |
Plastid outer membrane | |
Protein transport | |
Receptor | |
Reference proteome | |
Transmembrane | |
Transmembrane helix | |
Transport
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Chloroplast | |
Cellular Component | Chloroplast envelope | |
Cellular Component | Chloroplast outer membrane | |
Cellular Component | Cytosol | |
Cellular Component | Integral component of membrane | |
Cellular Component | Membrane | |
Cellular Component | Plastid | |
Cellular Component | TOC-TIC supercomplex I | |
Molecular Function | Chaperone binding | |
Molecular Function | G protein-coupled receptor activity | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | Metal ion binding | |
Molecular Function | Ribosomal small subunit binding | |
Molecular Function | Transmembrane signaling receptor activity | |
Biological Process | Protein import into chloroplast stroma | |
Biological Process | Protein targeting to chloroplast |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-1300 | Arabidopsis lyrata | 89.91 | 0.0 | 1961 |
| LLPS-Bro-1436 | Brassica oleracea | 88.5 | 0.0 | 1332 |
| LLPS-Vir-0202 | Vigna radiata | 77.17 | 2e-150 | 494 |
| LLPS-Mae-2239 | Manihot esculenta | 76.34 | 0.0 | 902 |
| LLPS-Coc-0067 | Corchorus capsularis | 75.9 | 0.0 | 1027 |
| LLPS-Brn-2675 | Brassica napus | 74.97 | 0.0 | 924 |
| LLPS-Thc-1291 | Theobroma cacao | 74.59 | 0.0 | 1014 |
| LLPS-Gor-2275 | Gossypium raimondii | 74.16 | 0.0 | 1009 |
| LLPS-Viv-2165 | Vitis vinifera | 72.41 | 0.0 | 981 |
| LLPS-Phv-2415 | Phaseolus vulgaris | 70.18 | 0.0 | 930 |
| LLPS-Glm-0613 | Glycine max | 69.96 | 0.0 | 915 |
| LLPS-Nia-2185 | Nicotiana attenuata | 69.27 | 0.0 | 939 |
| LLPS-Cus-0368 | Cucumis sativus | 69.11 | 0.0 | 837 |
| LLPS-Sot-1696 | Solanum tuberosum | 68.92 | 0.0 | 911 |
| LLPS-Via-0442 | Vigna angularis | 68.88 | 0.0 | 930 |
| LLPS-Mua-2234 | Musa acuminata | 68.8 | 3e-134 | 447 |
| LLPS-Sol-0983 | Solanum lycopersicum | 66.28 | 0.0 | 876 |
| LLPS-Prp-2410 | Prunus persica | 65.86 | 0.0 | 889 |
| LLPS-Brd-2518 | Brachypodium distachyon | 65.43 | 0.0 | 842 |
| LLPS-Hea-0027 | Helianthus annuus | 65.38 | 0.0 | 829 |
| LLPS-Lep-2342 | Leersia perrieri | 64.93 | 0.0 | 804 |
| LLPS-Hov-0414 | Hordeum vulgare | 64.93 | 0.0 | 840 |
| LLPS-Dac-0595 | Daucus carota | 64.92 | 0.0 | 857 |
| LLPS-Tru-1477 | Triticum urartu | 64.8 | 0.0 | 841 |
| LLPS-Tra-2917 | Triticum aestivum | 64.8 | 0.0 | 842 |
| LLPS-Met-2055 | Medicago truncatula | 63.98 | 0.0 | 771 |
| LLPS-Sob-1635 | Sorghum bicolor | 63.02 | 0.0 | 827 |
| LLPS-Orp-2002 | Oryza punctata | 62.57 | 0.0 | 834 |
| LLPS-Orm-1795 | Oryza meridionalis | 62.56 | 0.0 | 839 |
| LLPS-Zem-2437 | Zea mays | 62.51 | 0.0 | 823 |
| LLPS-Org-1431 | Oryza glaberrima | 62.44 | 0.0 | 842 |
| LLPS-Ori-1786 | Oryza indica | 62.44 | 0.0 | 842 |
| LLPS-Orb-2314 | Oryza barthii | 62.44 | 0.0 | 838 |
| LLPS-Orni-1331 | Oryza nivara | 62.44 | 0.0 | 841 |
| LLPS-Orgl-0028 | Oryza glumaepatula | 62.44 | 0.0 | 841 |
| LLPS-Sei-1808 | Setaria italica | 62.4 | 0.0 | 813 |
| LLPS-Orr-1773 | Oryza rufipogon | 62.33 | 0.0 | 840 |
| LLPS-Amt-0419 | Amborella trichopoda | 62.23 | 0.0 | 791 |
| LLPS-Ors-0368 | Oryza sativa | 62.21 | 0.0 | 840 |
| LLPS-Orbr-2002 | Oryza brachyantha | 62.1 | 0.0 | 832 |
| LLPS-Brr-2512 | Brassica rapa | 60.91 | 0.0 | 719 |
| LLPS-Pot-1274 | Populus trichocarpa | 58.74 | 0.0 | 741 |
| LLPS-Php-2459 | Physcomitrella patens | 52.21 | 2e-178 | 580 |
| LLPS-Osl-1448 | Ostreococcus lucimarinus | 50.0 | 5e-62 | 231 |
| LLPS-Sem-0818 | Selaginella moellendorffii | 39.22 | 9e-28 | 121 |
| LLPS-Chr-0975 | Chlamydomonas reinhardtii | 35.71 | 5e-22 | 104 |