LLPS-Art-0580
VDAC3
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Mitochondrial outer membrane protein porin 3; Protein HYPERSENSITIVE RESPONSE 2; Athsr2; Voltage-dependent anion-selective channel protein 3; AtVDAC3; VDAC-3 |
| Gene Name: | VDAC3, HSR2, At5g15090, F2G14.210 |
| Ensembl Gene: | AT5G15090 |
| Ensembl Protein: | AT5G15090.1 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...Here, we describe the first proteomic analysis of plant nucleoli, in which we have identified 217 proteins." | Protoplasts | 15496452 |
| Nucleolus | "...Comparative analysis revealed that 562 proteins were consistently identified in both experimental data sets." | 3 weeks-old Arabidopsis thaliana plants | 29104584 |
▼ FUNCTION
| Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT5G15090.1 | AT5G15090.1 |
| Ensembl | AT5G15090.2 | AT5G15090.2 |
| UniProt | Q9SMX3, VDAC3_ARATH, Q8L815, Q8LET4 | |
| GeneBank | AY063891, CP002688, AY085248, AL391146, AJ131391, AY122918 | AAM62480.1, CAA10363.1, CAC01828.1, AAL36247.1, AAM67451.1, AED92116.1, AED92115.1 |
| RefSeq | NM_001203385.1, NM_121513.5 | NP_001190314.1, NP_197013.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MVKGPGLYTE IGKKARDLLY RDYQGDQKFS VTTYSSTGVA ITTTGTNKGS LFLGDVATQV 60 61 KNNNFTADVK VSTDSSLLTT LTFDEPAPGL KVIVQAKLPD HKSGKAEVQY FHDYAGISTS 120 121 VGFTATPIVN FSGVVGTNGL SLGTDVAYNT ESGNFKHFNA GFNFTKDDLT ASLILNDKGE 180 181 KLNASYYQIV SPSTVVGAEI SHNFTTKENA ITVGTQHALD PLTTVKARVN NAGVANALIQ 240 241 HEWRPKSFFT VSGEVDSKAI DKSAKVGIAL ALKP 274 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGTTAAAG GTCCAGGACT CTACACTGAA ATCGGCAAAA AGGCCAGAGA TCTTCTGTAC 60 61 AGGGATTACC AAGGAGACCA GAAATTCAGT GTCACCACTT ACTCTTCAAC TGGTGTTGCG 120 121 ATCACTACAA CGGGAACAAA CAAAGGAAGC TTGTTTTTGG GTGATGTTGC TACCCAAGTG 180 181 AAGAACAACA ACTTCACTGC TGATGTCAAA GTTTCCACTG ATTCTTCTCT TTTGACCACT 240 241 CTTACCTTTG ATGAGCCTGC CCCTGGACTG AAAGTTATTG TTCAGGCTAA GTTGCCCGAT 300 301 CACAAATCTG GAAAGGCTGA GGTTCAGTAT TTCCATGACT ATGCTGGTAT CTCTACCAGC 360 361 GTTGGATTCA CAGCTACCCC GATTGTCAAC TTCTCCGGTG TGGTTGGAAC CAATGGTTTG 420 421 TCTCTTGGTA CTGATGTGGC CTATAACACC GAATCTGGCA ACTTCAAACA TTTCAATGCT 480 481 GGTTTCAACT TCACCAAGGA TGATTTGACT GCTTCCCTCA TTCTGAATGA CAAAGGTGAG 540 541 AAATTGAATG CATCCTACTA CCAGATTGTG AGCCCGTCGA CTGTGGTTGG AGCTGAGATT 600 601 AGCCACAACT TCACGACCAA AGAGAACGCC ATCACTGTCG GAACTCAACA CGCGCTTGAC 660 661 CCATTGACCA CAGTGAAGGC AAGAGTGAAC AATGCTGGTG TGGCTAACGC TCTGATCCAA 720 721 CATGAGTGGC GTCCAAAGTC GTTCTTCACC GTTTCTGGAG AGGTTGATTC TAAGGCGATC 780 781 GATAAGAGTG CCAAGGTTGG GATTGCTCTC GCTCTCAAGC CCTGA 825 |
▼ KEYWORD
ID | Family |
Cell membrane | |
Complete proteome | |
Direct protein sequencing | |
Hypersensitive response | |
Ion transport | |
Membrane | |
Mitochondrion | |
Mitochondrion outer membrane | |
Phosphoprotein | |
Plant defense | |
Porin | |
Reference proteome | |
Transmembrane | |
Transmembrane beta strand | |
Transport
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cell wall | |
Cellular Component | Chloroplast | |
Cellular Component | Chloroplast envelope | |
Cellular Component | Membrane | |
Cellular Component | Mitochondrial outer membrane | |
Cellular Component | Mitochondrion | |
Cellular Component | Nucleolus | |
Cellular Component | Plasma membrane | |
Cellular Component | Plastid | |
Cellular Component | Pore complex | |
Cellular Component | Vacuolar membrane | |
Cellular Component | Vacuole | |
Molecular Function | Porin activity | |
Molecular Function | Voltage-gated anion channel activity | |
Biological Process | Aerobic respiration | |
Biological Process | Defense response to bacterium | |
Biological Process | Plant-type hypersensitive response | |
Biological Process | Regulation of seed germination | |
Biological Process | Response to bacterium | |
Biological Process | Response to cold | |
Biological Process | Response to cytokinin |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Localization | ||||
| COMPARTMENTS | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-2767 | Arabidopsis lyrata | 93.12 | 2e-177 | 498 |
| LLPS-Brn-0920 | Brassica napus | 80.8 | 3e-155 | 441 |
| LLPS-Bro-1324 | Brassica oleracea | 80.43 | 7e-155 | 440 |
| LLPS-Brr-2218 | Brassica rapa | 77.9 | 8e-151 | 430 |
| LLPS-Hea-1647 | Helianthus annuus | 71.38 | 2e-138 | 399 |
| LLPS-Glm-0942 | Glycine max | 70.29 | 1e-134 | 389 |
| LLPS-Prp-1190 | Prunus persica | 70.29 | 6e-135 | 390 |
| LLPS-Cus-1932 | Cucumis sativus | 69.93 | 2e-134 | 388 |
| LLPS-Nia-2156 | Nicotiana attenuata | 69.93 | 2e-132 | 383 |
| LLPS-Thc-2459 | Theobroma cacao | 69.2 | 2e-133 | 386 |
| LLPS-Coc-0126 | Corchorus capsularis | 68.98 | 5e-134 | 387 |
| LLPS-Sol-1008 | Solanum lycopersicum | 68.84 | 5e-130 | 377 |
| LLPS-Sot-0774 | Solanum tuberosum | 68.84 | 3e-130 | 378 |
| LLPS-Gor-2556 | Gossypium raimondii | 68.48 | 2e-132 | 383 |
| LLPS-Phv-2278 | Phaseolus vulgaris | 68.48 | 7e-131 | 379 |
| LLPS-Viv-2146 | Vitis vinifera | 67.75 | 9e-131 | 379 |
| LLPS-Mae-0182 | Manihot esculenta | 67.52 | 3e-129 | 375 |
| LLPS-Pot-1765 | Populus trichocarpa | 67.39 | 5e-130 | 377 |
| LLPS-Vir-1534 | Vigna radiata | 65.94 | 2e-127 | 371 |
| LLPS-Via-1814 | Vigna angularis | 65.58 | 1e-126 | 369 |
| LLPS-Amt-1582 | Amborella trichopoda | 65.22 | 6e-125 | 364 |
| LLPS-Met-2467 | Medicago truncatula | 65.11 | 6e-125 | 364 |
| LLPS-Dac-1048 | Daucus carota | 62.18 | 2e-118 | 347 |
| LLPS-Orb-1598 | Oryza barthii | 61.76 | 4e-116 | 342 |
| LLPS-Ors-0024 | Oryza sativa | 61.76 | 4e-116 | 342 |
| LLPS-Orbr-0531 | Oryza brachyantha | 61.76 | 2e-116 | 343 |
| LLPS-Orni-0396 | Oryza nivara | 61.42 | 8e-106 | 333 |
| LLPS-Ori-0988 | Oryza indica | 61.4 | 3e-115 | 339 |
| LLPS-Mua-0994 | Musa acuminata | 61.31 | 1e-113 | 335 |
| LLPS-Orr-2082 | Oryza rufipogon | 61.13 | 2e-104 | 330 |
| LLPS-Lep-0817 | Leersia perrieri | 60.66 | 1e-113 | 335 |
| LLPS-Orm-0073 | Oryza meridionalis | 60.59 | 9e-106 | 329 |
| LLPS-Brd-1740 | Brachypodium distachyon | 59.85 | 4e-112 | 332 |
| LLPS-Tra-0887 | Triticum aestivum | 59.34 | 6e-111 | 328 |
| LLPS-Sob-1707 | Sorghum bicolor | 56.99 | 1e-100 | 302 |
| LLPS-Hov-1468 | Hordeum vulgare | 56.62 | 3e-92 | 283 |
| LLPS-Sei-1960 | Setaria italica | 56.32 | 4e-100 | 303 |
| LLPS-Zem-2407 | Zea mays | 56.25 | 4e-100 | 301 |
| LLPS-Orp-1801 | Oryza punctata | 56.09 | 2e-101 | 304 |
| LLPS-Tru-1310 | Triticum urartu | 55.84 | 8e-99 | 298 |
| LLPS-Orgl-1240 | Oryza glumaepatula | 54.95 | 2e-96 | 291 |
| LLPS-Php-0141 | Physcomitrella patens | 54.71 | 3e-95 | 288 |
| LLPS-Sem-0083 | Selaginella moellendorffii | 48.55 | 9e-80 | 249 |
| LLPS-Org-1774 | Oryza glaberrima | 45.09 | 9e-74 | 234 |
| LLPS-Drm-1166 | Drosophila melanogaster | 28.83 | 3e-17 | 82.8 |
| LLPS-Anc-2562 | Anolis carolinensis | 28.27 | 7e-12 | 68.2 |
| LLPS-Gaga-2444 | Gallus gallus | 28.11 | 3e-13 | 72.0 |
| LLPS-Meg-1243 | Meleagris gallopavo | 27.76 | 2e-12 | 69.7 |
| LLPS-Scp-0851 | Schizosaccharomyces pombe | 27.6 | 1e-11 | 67.4 |
| LLPS-Pes-2391 | Pelodiscus sinensis | 27.56 | 5e-14 | 73.9 |
| LLPS-Xet-2507 | Xenopus tropicalis | 27.34 | 2e-13 | 72.4 |
| LLPS-Anp-1076 | Anas platyrhynchos | 27.21 | 2e-13 | 72.4 |
| LLPS-Ten-3814 | Tetraodon nigroviridis | 27.05 | 3e-11 | 66.2 |
| LLPS-Gag-1096 | Gaeumannomyces graminis | 26.85 | 1e-07 | 55.8 |
| LLPS-Mao-1510 | Magnaporthe oryzae | 26.85 | 3e-09 | 60.8 |
| LLPS-Ved-0911 | Verticillium dahliae | 26.81 | 8e-08 | 56.6 |
| LLPS-Chc-0917 | Chondrus crispus | 26.69 | 1e-21 | 95.9 |
| LLPS-Orn-1869 | Oreochromis niloticus | 26.5 | 6e-12 | 68.6 |
| LLPS-Fia-0866 | Ficedula albicollis | 26.5 | 9e-11 | 65.1 |
| LLPS-Dar-2888 | Danio rerio | 26.46 | 2e-13 | 72.4 |
| LLPS-Gas-0374 | Galdieria sulphuraria | 26.45 | 3e-26 | 109 |
| LLPS-Dos-1054 | Dothistroma septosporum | 26.29 | 1e-07 | 56.2 |
| LLPS-Map-0116 | Magnaporthe poae | 26.17 | 8e-08 | 56.6 |
| LLPS-Dio-2132 | Dipodomys ordii | 26.07 | 2e-08 | 58.2 |
| LLPS-Icp-0789 | Ictalurus punctatus | 26.04 | 4e-11 | 65.9 |
| LLPS-Scf-0690 | Scleropages formosus | 26.04 | 3e-12 | 68.9 |
| LLPS-Ora-0737 | Ornithorhynchus anatinus | 25.86 | 2e-09 | 60.8 |
| LLPS-Gaa-2238 | Gasterosteus aculeatus | 25.71 | 3e-14 | 74.7 |
| LLPS-Abg-0293 | Absidia glauca | 25.71 | 6e-09 | 59.7 |
| LLPS-Aim-1813 | Ailuropoda melanoleuca | 25.71 | 3e-08 | 57.4 |
| LLPS-Cym-0238 | Cyanidioschyzon merolae | 25.66 | 3e-16 | 80.5 |
| LLPS-Tum-0948 | Tuber melanosporum | 25.64 | 3e-09 | 60.5 |
| LLPS-Myl-2466 | Myotis lucifugus | 25.62 | 1e-08 | 58.5 |
| LLPS-Orl-3880 | Oryzias latipes | 25.36 | 4e-14 | 74.3 |
| LLPS-Fud-0234 | Fukomys damarensis | 25.36 | 3e-07 | 54.7 |
| LLPS-Tut-0287 | Tursiops truncatus | 25.36 | 2e-07 | 55.1 |
| LLPS-Mup-1530 | Mustela putorius furo | 25.36 | 4e-07 | 54.3 |
| LLPS-Loa-1724 | Loxodonta africana | 25.36 | 4e-07 | 54.3 |
| LLPS-Urm-0261 | Ursus maritimus | 25.36 | 3e-07 | 54.7 |
| LLPS-Orc-0285 | Oryctolagus cuniculus | 25.36 | 3e-07 | 54.7 |
| LLPS-Cap-2842 | Cavia porcellus | 25.36 | 5e-07 | 53.9 |
| LLPS-Poa-1237 | Pongo abelii | 25.36 | 2e-07 | 55.5 |
| LLPS-Caf-4157 | Canis familiaris | 25.36 | 2e-07 | 55.1 |
| LLPS-Spr-0494 | Sporisorium reilianum | 25.35 | 8e-09 | 59.3 |
| LLPS-Lac-1246 | Latimeria chalumnae | 25.27 | 4e-12 | 68.9 |
| LLPS-Pap-1664 | Pan paniscus | 25.27 | 7e-08 | 56.6 |
| LLPS-Scc-0749 | Schizosaccharomyces cryophilus | 25.09 | 3e-08 | 57.8 |
| LLPS-Scj-1294 | Schizosaccharomyces japonicus | 25.09 | 8e-11 | 65.1 |
| LLPS-Cea-2552 | Cercocebus atys | 24.91 | 1e-06 | 53.1 |
| LLPS-Maf-2231 | Macaca fascicularis | 24.91 | 1e-06 | 53.1 |
| LLPS-Mum-3129 | Mus musculus | 24.91 | 6e-07 | 53.9 |
| LLPS-Caj-3330 | Callithrix jacchus | 24.91 | 5e-07 | 53.9 |
| LLPS-Gog-0920 | Gorilla gorilla | 24.91 | 9e-07 | 53.1 |
| LLPS-Mal-2462 | Mandrillus leucophaeus | 24.91 | 1e-06 | 53.1 |
| LLPS-Man-0178 | Macaca nemestrina | 24.91 | 1e-06 | 53.1 |
| LLPS-Pat-3396 | Pan troglodytes | 24.91 | 9e-07 | 53.1 |
| LLPS-Hos-2277 | Homo sapiens | 24.91 | 9e-07 | 53.1 |
| LLPS-Rhb-2074 | Rhinopithecus bieti | 24.91 | 1e-06 | 53.1 |
| LLPS-Mam-0420 | Macaca mulatta | 24.91 | 1e-06 | 53.1 |
| LLPS-Tag-2431 | Taeniopygia guttata | 24.91 | 2e-10 | 63.5 |
| LLPS-Ict-1025 | Ictidomys tridecemlineatus | 24.91 | 3e-11 | 66.6 |
| LLPS-Nol-2216 | Nomascus leucogenys | 24.91 | 1e-06 | 53.1 |
| LLPS-Cas-2985 | Carlito syrichta | 24.91 | 7e-07 | 53.5 |
| LLPS-Cae-1315 | Caenorhabditis elegans | 24.82 | 8e-08 | 56.6 |
| LLPS-Tar-2570 | Takifugu rubripes | 24.82 | 2e-09 | 61.2 |
| LLPS-Leo-0492 | Lepisosteus oculatus | 24.74 | 2e-13 | 72.4 |
| LLPS-Cii-0513 | Ciona intestinalis | 24.74 | 2e-12 | 69.7 |
| LLPS-Xim-0772 | Xiphophorus maculatus | 24.65 | 1e-11 | 67.4 |
| LLPS-Chs-3149 | Chlorocebus sabaeus | 24.62 | 6e-08 | 56.6 |
| LLPS-Sus-2803 | Sus scrofa | 24.56 | 3e-11 | 66.6 |
| LLPS-Bot-4312 | Bos taurus | 24.56 | 2e-10 | 63.9 |
| LLPS-Ova-1912 | Ovis aries | 24.56 | 5e-11 | 65.9 |
| LLPS-Paa-1944 | Papio anubis | 24.56 | 6e-11 | 65.9 |
| LLPS-Ran-1019 | Rattus norvegicus | 24.56 | 2e-08 | 58.2 |
| LLPS-Fec-0659 | Felis catus | 24.56 | 5e-11 | 65.9 |
| LLPS-Otg-1565 | Otolemur garnettii | 24.56 | 4e-11 | 66.2 |
| LLPS-Eqc-1807 | Equus caballus | 24.56 | 5e-11 | 65.9 |
| LLPS-Sah-1129 | Sarcophilus harrisii | 24.47 | 2e-09 | 61.2 |
| LLPS-Mea-1438 | Mesocricetus auratus | 24.47 | 2e-09 | 61.2 |
| LLPS-Usm-1193 | Ustilago maydis | 24.31 | 1e-07 | 55.8 |
| LLPS-Chr-1663 | Chlamydomonas reinhardtii | 24.25 | 4e-20 | 91.7 |
| LLPS-Asm-0035 | Astyanax mexicanus | 24.11 | 1e-10 | 64.3 |
| LLPS-Pof-2478 | Poecilia formosa | 23.96 | 1e-10 | 64.3 |
| LLPS-Kop-0934 | Komagataella pastoris | 23.86 | 1e-10 | 64.3 |
| LLPS-Yal-0484 | Yarrowia lipolytica | 23.72 | 3e-09 | 60.8 |
| LLPS-Ast-1093 | Aspergillus terreus | 23.66 | 8e-07 | 53.5 |
| LLPS-Mod-1268 | Monodelphis domestica | 23.49 | 4e-09 | 60.1 |
| LLPS-Cis-0657 | Ciona savignyi | 23.37 | 1e-09 | 61.6 |
| LLPS-Pyt-0320 | Pyrenophora teres | 23.13 | 7e-07 | 53.5 |
| LLPS-Scm-1253 | Scophthalmus maximus | 23.13 | 3e-08 | 57.8 |
| LLPS-Asc-0877 | Aspergillus clavatus | 22.92 | 8e-07 | 53.5 |
| LLPS-Lem-0750 | Leptosphaeria maculans | 22.56 | 2e-07 | 55.5 |
| LLPS-Asn-0811 | Aspergillus nidulans | 22.5 | 2e-07 | 55.5 |
| LLPS-Nef-0141 | Neosartorya fischeri | 21.79 | 1e-07 | 55.8 |