LLPS-Art-0371
At4g26870

▼ OVERVIEW

Status: Reviewed
Protein Name: Aspartate--tRNA ligase 1, cytoplasmic; Aspartyl-tRNA synthetase; AspRS
Gene Name: At4g26870, F10M23.210
Ensembl Gene: AT4G26870
Ensembl Protein: AT4G26870.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVGSEVLEEC  GEKISKKESK  KRAAKLEKLL  RKQEREEATS  SSLSLEEEDE  SCSSNYGDVT  60
61    TNELQSAVEG  KELTDVSNLV  EEIVGSEVSI  RGRLHKNRLV  GTKLFVILRE  SGFTVQCVVE  120
121   ETRVGANMIK  FVKQLSRESV  VELIGVVSHP  KKPLTGTTQQ  VEIHVRKMYC  LSRSLPNLPL  180
181   VVEDAARSES  DIEKSGKDGK  QAARVLQDTR  LNNRVLDIRT  PANQAIFRIQ  CQVQIAFREY  240
241   LQSKGFLEIH  TPKLIAGSSE  GGSAVFRLDY  KGQPACLAQS  PQLHKQMAIC  GDMRRVFEVG  300
301   PVFRAEDSFT  HRHLCEFVGL  DVEMEIRMHY  SEIMDLVGEL  FPFIFTKIEE  RCPKELESVR  360
361   KQYPFQSLKF  LPQTLRLTFA  EGIQMLKEAG  EEVDPLGDLN  TESERKLGQL  VLEKYKTEFY  420
421   MLHRYPSAVR  PFYTMPYEND  SNYSNSFDVF  IRGEEIMSGA  QRIHDPELLE  KRARECGIDV  480
481   KTISTYIDAF  RYGAPPHGGF  GVGLERVVML  LCALNNIRKT  SLFPRDSQRL  TP  532
Nucleotide CDS Sequence (FASTA)
1     ATGGTGGGAT  CAGAGGTTTT  GGAGGAATGT  GGAGAAAAAA  TAAGCAAGAA  AGAGTCAAAG  60
61    AAGCGAGCCG  CTAAACTGGA  GAAGTTGCTC  CGTAAACAGG  AACGAGAAGA  AGCCACATCA  120
121   TCATCTCTTT  CTCTGGAGGA  GGAGGATGAA  TCGTGTTCCA  GCAACTACGG  TGACGTGACT  180
181   ACTAACGAGT  TGCAGTCGGC  TGTTGAGGGA  AAAGAGCTCA  CTGATGTGAG  CAACTTGGTT  240
241   GAAGAGATTG  TGGGGTCAGA  GGTTTCGATC  AGAGGTCGAC  TGCACAAGAA  TCGCTTAGTC  300
301   GGTACCAAAT  TGTTTGTGAT  CTTGAGGGAA  AGTGGATTCA  CGGTTCAATG  CGTGGTGGAG  360
361   GAGACCAGAG  TTGGTGCAAA  CATGATTAAA  TTTGTCAAGC  AGCTGAGTCG  TGAATCTGTT  420
421   GTTGAGCTTA  TCGGTGTCGT  CTCTCACCCT  AAGAAGCCTC  TCACAGGAAC  CACCCAGCAG  480
481   GTTGAAATAC  ATGTCAGAAA  AATGTACTGC  CTCAGCAGAT  CCTTGCCAAA  TTTACCACTT  540
541   GTTGTGGAGG  ATGCTGCTCG  TAGTGAATCA  GATATTGAAA  AATCTGGCAA  GGATGGCAAA  600
601   CAAGCTGCTC  GTGTCCTTCA  GGACACACGT  TTGAATAATA  GGGTTCTTGA  CATCAGAACA  660
661   CCGGCTAATC  AAGCCATCTT  CCGTATTCAG  TGCCAAGTCC  AAATTGCGTT  CAGAGAATAC  720
721   TTACAATCCA  AGGGGTTTCT  TGAAATCCAC  ACACCGAAAT  TGATCGCTGG  CAGTAGTGAA  780
781   GGAGGTTCTG  CTGTGTTTAG  GTTGGACTAC  AAAGGGCAGC  CTGCTTGTCT  GGCTCAGTCT  840
841   CCTCAGCTTC  ATAAGCAGAT  GGCGATATGT  GGTGACATGC  GACGCGTCTT  TGAGGTTGGT  900
901   CCTGTTTTCA  GAGCTGAAGA  CTCCTTCACT  CATAGACACC  TGTGTGAATT  CGTTGGTCTT  960
961   GATGTGGAGA  TGGAGATTCG  AATGCACTAC  TCTGAGATAA  TGGATCTTGT  GGGGGAGTTG  1020
1021  TTTCCGTTCA  TATTCACAAA  AATAGAAGAA  AGGTGCCCAA  AGGAACTTGA  ATCTGTCAGA  1080
1081  AAGCAATACC  CTTTTCAATC  TTTGAAGTTT  CTTCCGCAAA  CATTGAGGCT  AACCTTTGCA  1140
1141  GAAGGGATTC  AAATGCTTAA  GGAAGCTGGC  GAGGAGGTTG  ATCCTCTTGG  TGATCTAAAT  1200
1201  ACAGAATCTG  AGAGGAAACT  TGGCCAGCTT  GTTCTGGAAA  AGTACAAGAC  GGAGTTCTAC  1260
1261  ATGCTGCATC  GCTATCCATC  GGCTGTCAGA  CCGTTCTACA  CTATGCCCTA  TGAAAATGAT  1320
1321  TCTAACTACA  GCAACTCTTT  CGATGTCTTC  ATCAGAGGAG  AGGAGATCAT  GTCAGGAGCT  1380
1381  CAACGTATCC  ATGACCCAGA  ACTCTTGGAG  AAGCGCGCAA  GAGAATGCGG  CATTGATGTC  1440
1441  AAGACAATAT  CCACGTACAT  TGATGCATTC  AGGTACGGTG  CACCACCTCA  CGGTGGATTC  1500
1501  GGAGTGGGGC  TGGAGCGTGT  GGTAATGCTC  TTATGTGCCC  TCAATAACAT  CCGCAAAACT  1560
1561  TCGCTATTCC  CTCGTGACTC  TCAAAGGCTC  ACTCCCTAA  1599

▼ KEYWORD

ID
Family
Aminoacyl-tRNA synthetase
ATP-binding
Coiled coil
Complete proteome
Cytoplasm
DNA-binding
Ligase
Magnesium
Metal-binding
Nucleotide-binding
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Aminoacyl-tRNA synthetase multienzyme complex
Cellular Component
Cytosol
Cellular Component
Plasmodesma
Molecular Function
Aspartate-tRNA ligase activity
Molecular Function
ATP binding
Molecular Function
DNA binding
Molecular Function
Metal ion binding
Molecular Function
RNA binding
Biological Process
Aspartyl-tRNA aminoacylation
Biological Process
Response to cadmium ion

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
Compute pI/MwAAindex
Function
PIRSF
Localization
COMPARTMENTS
Expression
ArrayExpress

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-2456Arabidopsis lyrata93.720.0 905
LLPS-Brn-0177Brassica napus91.420.0 897
LLPS-Bro-0399Brassica oleracea90.060.0 891
LLPS-Brr-0891Brassica rapa76.670.0 766
LLPS-Prp-1926Prunus persica72.437e-160 464
LLPS-Mua-0977Musa acuminata70.860.0 613
LLPS-Sol-1039Solanum lycopersicum70.390.0 704
LLPS-Tru-0888Triticum urartu69.362e-148 435
LLPS-Coc-0347Corchorus capsularis68.970.0 671
LLPS-Orb-0244Oryza barthii68.680.0 627
LLPS-Dac-1911Daucus carota68.530.0 680
LLPS-Mae-0460Manihot esculenta68.530.0 682
LLPS-Viv-2104Vitis vinifera68.460.0 674
LLPS-Gor-0016Gossypium raimondii68.290.0 697
LLPS-Glm-2971Glycine max68.120.0 674
LLPS-Cus-1654Cucumis sativus68.120.0 681
LLPS-Nia-0494Nicotiana attenuata68.110.0 681
LLPS-Vir-0448Vigna radiata67.080.0 667
LLPS-Thc-1325Theobroma cacao67.070.0 673
LLPS-Via-1208Vigna angularis66.870.0 666
LLPS-Met-0080Medicago truncatula66.870.0 671
LLPS-Hea-0480Helianthus annuus66.60.0 662
LLPS-Amt-1480Amborella trichopoda66.390.0 658
LLPS-Orp-0804Oryza punctata65.840.0 659
LLPS-Orgl-1425Oryza glumaepatula65.70.0 655
LLPS-Ori-0879Oryza indica65.630.0 658
LLPS-Orni-0606Oryza nivara65.630.0 658
LLPS-Orr-1283Oryza rufipogon65.630.0 658
LLPS-Orm-1205Oryza meridionalis65.630.0 658
LLPS-Org-0320Oryza glaberrima65.630.0 658
LLPS-Php-0814Physcomitrella patens65.490.0 648
LLPS-Ors-0370Oryza sativa65.420.0 657
LLPS-Brd-0842Brachypodium distachyon65.220.0 662
LLPS-Phv-1593Phaseolus vulgaris65.220.0 646
LLPS-Orbr-0842Oryza brachyantha65.010.0 657
LLPS-Pot-0112Populus trichocarpa64.940.0 659
LLPS-Sei-1468Setaria italica64.60.0 652
LLPS-Zem-1723Zea mays64.60.0 652
LLPS-Sob-1416Sorghum bicolor64.390.0 650
LLPS-Lep-1149Leersia perrieri64.180.0 648
LLPS-Tra-0932Triticum aestivum64.180.0 655
LLPS-Hov-0229Hordeum vulgare63.770.0 650
LLPS-Asm-0283Astyanax mexicanus63.565e-47 174
LLPS-Sem-0933Selaginella moellendorffii63.280.0 636
LLPS-Cis-0259Ciona savignyi57.461e-106 327
LLPS-Osl-0460Ostreococcus lucimarinus57.380.0 556
LLPS-Chr-0835Chlamydomonas reinhardtii56.640.0 547
LLPS-Sah-0946Sarcophilus harrisii53.224e-145 431
LLPS-Gas-0313Galdieria sulphuraria51.686e-146 452
LLPS-Aim-2178Ailuropoda melanoleuca51.157e-150 444
LLPS-Tag-1425Taeniopygia guttata51.085e-161 474
LLPS-Cym-0599Cyanidioschyzon merolae50.884e-153 457
LLPS-Anp-1585Anas platyrhynchos50.876e-160 472
LLPS-Fia-1908Ficedula albicollis50.874e-161 475
LLPS-Leo-0466Lepisosteus oculatus50.653e-158 469
LLPS-Orc-0269Oryctolagus cuniculus50.656e-158 467
LLPS-Gaga-1210Gallus gallus50.652e-158 468
LLPS-Abg-1180Absidia glauca50.529e-164 484
LLPS-Mum-0551Mus musculus50.435e-158 467
LLPS-Ova-1847Ovis aries50.433e-158 468
LLPS-Fec-0567Felis catus50.438e-157 464
LLPS-Xet-1664Xenopus tropicalis50.431e-159 473
LLPS-Cea-0620Cercocebus atys50.224e-153 454
LLPS-Chs-0606Chlorocebus sabaeus50.224e-153 454
LLPS-Maf-1046Macaca fascicularis50.224e-153 454
LLPS-Gog-1071Gorilla gorilla50.221e-153 456
LLPS-Dio-0420Dipodomys ordii50.226e-157 464
LLPS-Mup-0369Mustela putorius furo50.221e-156 464
LLPS-Paa-0789Papio anubis50.224e-153 454
LLPS-Man-0786Macaca nemestrina50.224e-153 454
LLPS-Hos-0086Homo sapiens50.221e-153 456
LLPS-Urm-0364Ursus maritimus50.221e-156 464
LLPS-Pap-1410Pan paniscus50.221e-153 456
LLPS-Rhb-2398Rhinopithecus bieti50.224e-153 454
LLPS-Pes-2700Pelodiscus sinensis50.228e-157 464
LLPS-Mam-1559Macaca mulatta50.224e-153 454
LLPS-Caf-0204Canis familiaris50.221e-156 464
LLPS-Nol-3237Nomascus leucogenys50.222e-153 456
LLPS-Myl-0225Myotis lucifugus50.219e-161 474
LLPS-Sus-0995Sus scrofa50.01e-156 464
LLPS-Aon-0713Aotus nancymaae50.06e-153 454
LLPS-Caj-0175Callithrix jacchus50.07e-153 454
LLPS-Scf-0254Scleropages formosus50.05e-159 471
LLPS-Drm-0785Drosophila melanogaster50.02e-155 462
LLPS-Mal-1353Mandrillus leucophaeus50.07e-153 454
LLPS-Pat-0060Pan troglodytes50.03e-154 457
LLPS-Gaa-2236Gasterosteus aculeatus49.789e-157 465
LLPS-Tut-0010Tursiops truncatus49.782e-156 463
LLPS-Ran-2675Rattus norvegicus49.788e-157 464
LLPS-Mod-1237Monodelphis domestica49.781e-155 461
LLPS-Dar-0146Danio rerio49.781e-156 465
LLPS-Otg-0969Otolemur garnettii49.782e-152 453
LLPS-Icp-2430Ictalurus punctatus49.573e-157 464
LLPS-Cas-0948Carlito syrichta49.572e-156 463
LLPS-Pof-1973Poecilia formosa49.467e-157 466
LLPS-Bot-2057Bos taurus49.422e-142 428
LLPS-Fud-0024Fukomys damarensis49.372e-158 468
LLPS-Ict-0393Ictidomys tridecemlineatus49.372e-157 466
LLPS-Tar-0761Takifugu rubripes49.359e-157 465
LLPS-Xim-2608Xiphophorus maculatus49.356e-158 468
LLPS-Scm-1586Scophthalmus maximus49.351e-155 462
LLPS-Orn-1262Oreochromis niloticus49.356e-157 466
LLPS-Yal-0309Yarrowia lipolytica49.158e-153 456
LLPS-Loa-0120Loxodonta africana49.147e-153 454
LLPS-Ten-1503Tetraodon nigroviridis49.139e-156 462
LLPS-Sac-1171Saccharomyces cerevisiae49.121e-144 435
LLPS-Chc-0237Chondrus crispus49.083e-151 452
LLPS-Cap-1961Cavia porcellus48.951e-155 461
LLPS-Poa-1157Pongo abelii48.921e-148 443
LLPS-Cii-0164Ciona intestinalis48.752e-158 469
LLPS-Lac-0861Latimeria chalumnae48.713e-154 459
LLPS-Orl-0459Oryzias latipes48.491e-153 457
LLPS-Anc-1441Anolis carolinensis48.273e-153 456
LLPS-Kop-0372Komagataella pastoris48.256e-148 443
LLPS-Eqc-3244Equus caballus48.052e-152 454
LLPS-Meg-1348Meleagris gallopavo47.953e-144 432
LLPS-Tum-0189Tuber melanosporum47.856e-145 436
LLPS-Asg-0730Ashbya gossypii47.542e-146 440
LLPS-Crn-0291Cryptococcus neoformans47.052e-150 450
LLPS-Usm-0731Ustilago maydis46.915e-144 434
LLPS-Scp-0716Schizosaccharomyces pombe46.751e-142 431
LLPS-Lem-0005Leptosphaeria maculans46.428e-126 386
LLPS-Spr-0257Sporisorium reilianum46.091e-141 427
LLPS-Cae-0683Caenorhabditis elegans45.964e-147 440
LLPS-Scj-1349Schizosaccharomyces japonicus45.942e-134 409
LLPS-Pug-0067Puccinia graminis45.857e-142 427
LLPS-Pytr-1042Pyrenophora triticirepentis45.777e-125 384
LLPS-Miv-0093Microbotryum violaceum45.491e-142 432
LLPS-Pyt-0442Pyrenophora teres45.121e-122 378
LLPS-Ora-1447Ornithorhynchus anatinus45.042e-135 409
LLPS-Phn-0670Phaeosphaeria nodorum44.845e-122 377
LLPS-Mel-0947Melampsora laricipopulina44.673e-142 428
LLPS-Scc-0517Schizosaccharomyces cryophilus44.491e-132 405
LLPS-Aso-0535Aspergillus oryzae44.213e-122 389
LLPS-Asf-1193Aspergillus flavus44.213e-122 389
LLPS-Asc-1411Aspergillus clavatus44.191e-124 383
LLPS-Mea-2653Mesocricetus auratus43.622e-116 357
LLPS-Asfu-0316Aspergillus fumigatus43.555e-122 377
LLPS-Nef-0721Neosartorya fischeri43.349e-122 376
LLPS-Asni-0697Aspergillus niger43.162e-119 370
LLPS-Dos-0062Dothistroma septosporum43.123e-125 398
LLPS-Coo-1274Colletotrichum orbiculare42.984e-113 363
LLPS-Asn-0262Aspergillus nidulans42.926e-121 374
LLPS-Map-1036Magnaporthe poae42.783e-96 306
LLPS-Ast-0579Aspergillus terreus42.774e-124 382
LLPS-Cog-1266Colletotrichum gloeosporioides41.877e-110 355
LLPS-Zyt-0163Zymoseptoria tritici41.682e-124 393
LLPS-Nec-1371Neurospora crassa41.257e-114 365
LLPS-Beb-0829Beauveria bassiana41.218e-112 359
LLPS-Ved-1459Verticillium dahliae41.21e-105 342
LLPS-Gag-1324Gaeumannomyces graminis40.81e-105 335
LLPS-Blg-0815Blumeria graminis40.562e-92 300
LLPS-Trr-0901Trichoderma reesei40.528e-111 355
LLPS-Mao-1391Magnaporthe oryzae40.261e-109 355
LLPS-Trv-1003Trichoderma virens40.178e-110 352
LLPS-Cogr-1405Colletotrichum graminicola40.178e-108 349
LLPS-Fuv-1553Fusarium verticillioides39.784e-108 346
LLPS-Fuo-0490Fusarium oxysporum39.572e-106 347
LLPS-Put-0480Puccinia triticina38.927e-87 281
LLPS-Fus-1241Fusarium solani38.93e-101 330
LLPS-Scs-1077Sclerotinia sclerotiorum38.341e-87 288