LLPS-Art-0189
LPD1
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Dihydrolipoyl dehydrogenase 1, mitochondrial |
| Gene Name: | LPD1, At1g48030, F21D18.28, T2J15.6 |
| Ensembl Gene: | AT1G48030 |
| Ensembl Protein: | AT1G48030.4 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
▼ FUNCTION
| Lipoamide dehydrogenase is a component of the glycine decarboxylase (GDC) or glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. LPD1 is probably the protein most often associated with the glycine decarboxylase complex while LPD2 is probably incorporated into alpha-ketoacid dehydrogenase complexes. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT1G48030.4 | AT1G48030.4 |
| Ensembl | AT1G48030.3 | AT1G48030.3 |
| Ensembl | AT1G48030.5 | AT1G48030.5 |
| Ensembl | AT1G48030.1 | AT1G48030.1 |
| Ensembl | AT1G48030.2 | AT1G48030.2 |
| UniProt | Q9M5K3, DLDH1_ARATH, Q9LNF3 | |
| GeneBank | AC023673, CP002684, AF228639, AC051631 | AEE32239.1, ANM59709.1, AAG51522.1, ANM59707.1, AEE32240.1, AAF79529.1, AAF34795.3, ANM59708.1 |
| RefSeq | NM_001333291.1, NM_001333289.1, NM_001333290.1, NM_103699.5, NM_179451.1 | NP_001322047.1, NP_001322048.1, NP_001322049.1, NP_175237.1, NP_849782.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAMASLARRK AYFLTRNLSN SPTDALRFSF SLSRGFASSG SDENDVVIIG GGPGGYVAAI 60 61 KASQLGLKTT CIEKRGALGG TCLNVGCIPS KALLHSSHMY HEAKHSFANH GIKVSSVEVD 120 121 LPAMLAQKDN AVKNLTRGIE GLFKKNKVTY VKGYGKFISP NEVSVETIDG GNTIVKGKHI 180 181 IVATGSDVKS LPGITIDEKK IVSSTGALSL SEVPKKLIVI GAGYIGLEMG SVWGRLGSEV 240 241 TVVEFAGDIV PSMDGEIRKQ FQRSLEKQKM KFMLKTKVVS VDSSSDGVKL TVEPAEGGEQ 300 301 SILEADVVLV SAGRTPFTSG LDLEKIGVET DKAGRILVND RFLSNVPGVY AIGDVIPGPM 360 361 LAHKAEEDGV ACVEFIAGKH GHVDYDKVPG VVYTHPEVAS VGKTEEQLKK EGVSYRVGKF 420 421 PFMANSRAKA IDNAEGLVKI LADKETDKIL GVHIMAPNAG ELIHEAVLAI NYDASSEDIA 480 481 RVCHAHPTMS EALKEAAMAT YDKPIHI 507 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGATGG CGAGTTTAGC TAGGAGGAAG GCGTATTTTC TCACCAGAAA CTTATCAAAC 60 61 TCTCCCACTG ACGCTCTCAG ATTCTCCTTT TCCCTCTCCC GTGGCTTCGC CTCATCAGGA 120 121 TCTGATGAAA ACGACGTCGT CATCATCGGC GGCGGTCCCG GTGGTTACGT AGCCGCGATC 180 181 AAAGCCTCTC AGCTTGGTCT CAAAACCACT TGTATCGAGA AACGCGGCGC TCTCGGTGGT 240 241 ACTTGTCTCA ACGTCGGTTG CATTCCTTCC AAGGCTCTGC TTCACTCTTC ACATATGTAC 300 301 CATGAGGCGA AGCATTCCTT CGCTAACCAT GGTATTAAGG TCTCTTCTGT TGAGGTAGAT 360 361 CTTCCTGCTA TGTTGGCTCA GAAAGATAAT GCGGTTAAGA ACCTCACTCG TGGTATTGAG 420 421 GGTTTGTTCA AGAAAAATAA GGTGACTTAT GTCAAAGGAT ATGGTAAGTT TATTTCCCCA 480 481 AATGAAGTCT CGGTGGAGAC TATTGATGGA GGAAACACTA TTGTGAAAGG TAAACATATC 540 541 ATTGTTGCTA CTGGCTCGGA TGTTAAGTCC TTGCCTGGTA TTACGATTGA TGAAAAGAAG 600 601 ATTGTTTCGT CGACTGGAGC GTTGTCTCTA TCGGAAGTTC CGAAGAAATT GATTGTTATT 660 661 GGTGCGGGGT ATATTGGGCT TGAGATGGGT TCTGTTTGGG GTAGGCTTGG ATCTGAGGTT 720 721 ACGGTTGTTG AGTTTGCTGG AGATATTGTT CCTTCGATGG ATGGTGAAAT TCGTAAGCAG 780 781 TTTCAACGTT CTCTTGAGAA GCAGAAGATG AAGTTCATGC TCAAGACTAA AGTTGTTTCT 840 841 GTGGATTCCT CCTCTGATGG TGTGAAGCTT ACAGTGGAAC CGGCAGAAGG AGGAGAGCAG 900 901 TCTATTCTGG AAGCTGATGT GGTACTTGTC TCAGCGGGAA GAACACCGTT CACTTCTGGA 960 961 CTTGATCTGG AGAAAATCGG AGTGGAAACT GACAAAGCCG GGAGGATTCT GGTGAATGAT 1020 1021 AGATTCTTGA GTAATGTCCC AGGCGTGTAT GCTATTGGAG ATGTGATTCC AGGACCAATG 1080 1081 CTTGCTCACA AAGCCGAAGA AGACGGTGTT GCTTGTGTGG AGTTCATAGC AGGCAAACAC 1140 1141 GGTCATGTTG ATTATGACAA GGTTCCTGGT GTTGTTTACA CTCATCCTGA GGTTGCTTCG 1200 1201 GTTGGTAAAA CCGAAGAACA GCTGAAGAAA GAAGGTGTGA GTTACCGGGT TGGGAAATTC 1260 1261 CCGTTTATGG CGAATAGCAG AGCTAAGGCT ATTGATAATG CAGAAGGATT GGTTAAGATT 1320 1321 CTGGCCGATA AGGAGACTGA TAAGATCTTG GGCGTTCACA TTATGGCGCC AAACGCTGGA 1380 1381 GAGCTGATTC ATGAGGCTGT TCTTGCGATT AACTACGATG CATCAAGTGA AGACATTGCT 1440 1441 CGAGTCTGCC ATGCTCATCC CACTATGAGC GAGGCTCTTA AGGAAGCTGC CATGGCCACC 1500 1501 TATGACAAGC CTATTCACAT CTAA 1524 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Apoplast | |
Cellular Component | Mitochondrial matrix | |
Cellular Component | Mitochondrial respiratory chain complex I | |
Cellular Component | Mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | Cobalt ion binding | |
Molecular Function | Copper ion binding | |
Molecular Function | Dihydrolipoyl dehydrogenase activity | |
Molecular Function | Electron transfer activity | |
Molecular Function | Flavin adenine dinucleotide binding | |
Molecular Function | Zinc ion binding | |
Biological Process | Cell redox homeostasis | |
Biological Process | Response to cadmium ion |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-1554 | Arabidopsis lyrata | 98.81 | 0.0 | 961 |
| LLPS-Brn-2976 | Brassica napus | 95.07 | 0.0 | 935 |
| LLPS-Brr-2389 | Brassica rapa | 94.87 | 0.0 | 932 |
| LLPS-Bro-2903 | Brassica oleracea | 94.48 | 0.0 | 932 |
| LLPS-Coc-2076 | Corchorus capsularis | 88.43 | 0.0 | 881 |
| LLPS-Gor-0418 | Gossypium raimondii | 88.24 | 0.0 | 869 |
| LLPS-Thc-0675 | Theobroma cacao | 87.84 | 0.0 | 874 |
| LLPS-Mae-1519 | Manihot esculenta | 86.67 | 0.0 | 866 |
| LLPS-Prp-0573 | Prunus persica | 85.85 | 0.0 | 853 |
| LLPS-Met-2308 | Medicago truncatula | 85.63 | 0.0 | 835 |
| LLPS-Cus-0254 | Cucumis sativus | 85.63 | 0.0 | 854 |
| LLPS-Pot-1557 | Populus trichocarpa | 85.52 | 0.0 | 842 |
| LLPS-Nia-0435 | Nicotiana attenuata | 85.04 | 0.0 | 832 |
| LLPS-Via-1611 | Vigna angularis | 84.62 | 0.0 | 822 |
| LLPS-Sol-2415 | Solanum lycopersicum | 84.22 | 0.0 | 828 |
| LLPS-Phv-1054 | Phaseolus vulgaris | 84.22 | 0.0 | 819 |
| LLPS-Sot-0560 | Solanum tuberosum | 83.83 | 0.0 | 825 |
| LLPS-Vir-1608 | Vigna radiata | 83.83 | 0.0 | 822 |
| LLPS-Glm-1959 | Glycine max | 83.04 | 0.0 | 813 |
| LLPS-Viv-1307 | Vitis vinifera | 82.94 | 0.0 | 806 |
| LLPS-Ori-1588 | Oryza indica | 82.55 | 0.0 | 754 |
| LLPS-Tra-0968 | Triticum aestivum | 82.55 | 0.0 | 755 |
| LLPS-Dac-2386 | Daucus carota | 82.32 | 0.0 | 794 |
| LLPS-Orbr-1723 | Oryza brachyantha | 81.17 | 0.0 | 671 |
| LLPS-Hea-2448 | Helianthus annuus | 80.23 | 0.0 | 786 |
| LLPS-Amt-0127 | Amborella trichopoda | 79.68 | 0.0 | 786 |
| LLPS-Hov-1226 | Hordeum vulgare | 78.9 | 0.0 | 766 |
| LLPS-Brd-1799 | Brachypodium distachyon | 78.9 | 0.0 | 771 |
| LLPS-Zem-1189 | Zea mays | 78.7 | 0.0 | 766 |
| LLPS-Sei-1984 | Setaria italica | 78.5 | 0.0 | 762 |
| LLPS-Sob-0884 | Sorghum bicolor | 78.5 | 0.0 | 763 |
| LLPS-Tru-0507 | Triticum urartu | 78.46 | 0.0 | 741 |
| LLPS-Orni-1418 | Oryza nivara | 78.39 | 0.0 | 768 |
| LLPS-Orgl-0776 | Oryza glumaepatula | 78.39 | 0.0 | 768 |
| LLPS-Ors-1375 | Oryza sativa | 78.39 | 0.0 | 768 |
| LLPS-Orr-0599 | Oryza rufipogon | 78.39 | 0.0 | 768 |
| LLPS-Orb-0198 | Oryza barthii | 78.3 | 0.0 | 757 |
| LLPS-Orm-0259 | Oryza meridionalis | 78.3 | 0.0 | 758 |
| LLPS-Org-0685 | Oryza glaberrima | 78.3 | 0.0 | 757 |
| LLPS-Orp-0718 | Oryza punctata | 78.24 | 0.0 | 762 |
| LLPS-Lep-1614 | Leersia perrieri | 78.15 | 0.0 | 759 |
| LLPS-Mua-2199 | Musa acuminata | 77.62 | 0.0 | 755 |
| LLPS-Php-0611 | Physcomitrella patens | 77.42 | 0.0 | 709 |
| LLPS-Sem-0563 | Selaginella moellendorffii | 75.58 | 0.0 | 703 |
| LLPS-Chc-0499 | Chondrus crispus | 64.73 | 0.0 | 579 |
| LLPS-Spr-1002 | Sporisorium reilianum | 63.45 | 0.0 | 570 |
| LLPS-Usm-0472 | Ustilago maydis | 63.03 | 0.0 | 570 |
| LLPS-Chr-0497 | Chlamydomonas reinhardtii | 62.84 | 0.0 | 588 |
| LLPS-Crn-0304 | Cryptococcus neoformans | 62.18 | 0.0 | 563 |
| LLPS-Osl-0873 | Ostreococcus lucimarinus | 61.73 | 0.0 | 544 |
| LLPS-Gas-1372 | Galdieria sulphuraria | 61.72 | 0.0 | 567 |
| LLPS-Yal-1290 | Yarrowia lipolytica | 61.38 | 0.0 | 526 |
| LLPS-Mel-1369 | Melampsora laricipopulina | 59.72 | 9e-179 | 520 |
| LLPS-Asc-1346 | Aspergillus clavatus | 59.5 | 0.0 | 532 |
| LLPS-Nef-0811 | Neosartorya fischeri | 59.12 | 5e-178 | 518 |
| LLPS-Pug-0871 | Puccinia graminis | 59.1 | 0.0 | 555 |
| LLPS-Cym-1046 | Cyanidioschyzon merolae | 58.86 | 0.0 | 549 |
| LLPS-Drm-0975 | Drosophila melanogaster | 58.76 | 2e-176 | 513 |
| LLPS-Abg-0728 | Absidia glauca | 58.68 | 2e-179 | 522 |
| LLPS-Asni-0138 | Aspergillus niger | 58.61 | 7e-171 | 499 |
| LLPS-Ast-0991 | Aspergillus terreus | 58.53 | 4e-178 | 518 |
| LLPS-Dos-0596 | Dothistroma septosporum | 58.51 | 0.0 | 538 |
| LLPS-Asfu-0931 | Aspergillus fumigatus | 58.49 | 1e-177 | 517 |
| LLPS-Cog-0956 | Colletotrichum gloeosporioides | 58.4 | 3e-167 | 516 |
| LLPS-Cae-1104 | Caenorhabditis elegans | 58.14 | 0.0 | 533 |
| LLPS-Scs-0420 | Sclerotinia sclerotiorum | 58.02 | 2e-174 | 509 |
| LLPS-Scc-0112 | Schizosaccharomyces cryophilus | 57.97 | 0.0 | 525 |
| LLPS-Mea-0286 | Mesocricetus auratus | 57.87 | 2e-177 | 516 |
| LLPS-Miv-0544 | Microbotryum violaceum | 57.68 | 1e-171 | 501 |
| LLPS-Scf-1894 | Scleropages formosus | 57.65 | 6e-177 | 515 |
| LLPS-Cogr-1336 | Colletotrichum graminicola | 57.54 | 6e-180 | 523 |
| LLPS-Ved-0004 | Verticillium dahliae | 57.46 | 2e-177 | 516 |
| LLPS-Fuv-0782 | Fusarium verticillioides | 57.44 | 2e-174 | 508 |
| LLPS-Maf-2355 | Macaca fascicularis | 57.43 | 2e-177 | 516 |
| LLPS-Cea-2787 | Cercocebus atys | 57.43 | 6e-177 | 515 |
| LLPS-Icp-0801 | Ictalurus punctatus | 57.43 | 7e-176 | 512 |
| LLPS-Bot-1107 | Bos taurus | 57.43 | 4e-177 | 515 |
| LLPS-Ran-2444 | Rattus norvegicus | 57.43 | 4e-176 | 513 |
| LLPS-Paa-4135 | Papio anubis | 57.43 | 4e-177 | 516 |
| LLPS-Hos-1903 | Homo sapiens | 57.43 | 9e-177 | 514 |
| LLPS-Fec-1080 | Felis catus | 57.43 | 6e-176 | 512 |
| LLPS-Man-1491 | Macaca nemestrina | 57.43 | 3e-177 | 516 |
| LLPS-Ten-2995 | Tetraodon nigroviridis | 57.43 | 2e-175 | 511 |
| LLPS-Mam-4547 | Macaca mulatta | 57.43 | 2e-177 | 516 |
| LLPS-Ict-3515 | Ictidomys tridecemlineatus | 57.43 | 3e-176 | 513 |
| LLPS-Scp-1094 | Schizosaccharomyces pombe | 57.42 | 6e-178 | 518 |
| LLPS-Fuo-0113 | Fusarium oxysporum | 57.23 | 3e-174 | 508 |
| LLPS-Chs-1548 | Chlorocebus sabaeus | 57.21 | 9e-177 | 516 |
| LLPS-Sus-2732 | Sus scrofa | 57.21 | 5e-176 | 513 |
| LLPS-Gog-2219 | Gorilla gorilla | 57.21 | 4e-176 | 513 |
| LLPS-Fud-0498 | Fukomys damarensis | 57.21 | 3e-176 | 513 |
| LLPS-Caj-1031 | Callithrix jacchus | 57.21 | 6e-176 | 512 |
| LLPS-Gaa-0469 | Gasterosteus aculeatus | 57.21 | 6e-172 | 502 |
| LLPS-Ere-0711 | Erinaceus europaeus | 57.21 | 2e-174 | 508 |
| LLPS-Mal-0096 | Mandrillus leucophaeus | 57.21 | 9e-177 | 515 |
| LLPS-Mup-2956 | Mustela putorius furo | 57.21 | 1e-176 | 514 |
| LLPS-Ova-0370 | Ovis aries | 57.21 | 1e-176 | 514 |
| LLPS-Myl-2574 | Myotis lucifugus | 57.21 | 9e-178 | 516 |
| LLPS-Dar-4067 | Danio rerio | 57.21 | 4e-174 | 508 |
| LLPS-Pat-1838 | Pan troglodytes | 57.21 | 2e-176 | 514 |
| LLPS-Scm-3496 | Scophthalmus maximus | 57.21 | 4e-172 | 503 |
| LLPS-Cap-0489 | Cavia porcellus | 57.21 | 6e-177 | 515 |
| LLPS-Nol-2456 | Nomascus leucogenys | 57.21 | 3e-176 | 513 |
| LLPS-Cis-1131 | Ciona savignyi | 57.14 | 2e-171 | 501 |
| LLPS-Sac-1059 | Saccharomyces cerevisiae | 57.14 | 8e-169 | 494 |
| LLPS-Put-0732 | Puccinia triticina | 57.14 | 0.0 | 536 |
| LLPS-Coo-0189 | Colletotrichum orbiculare | 57.02 | 3e-171 | 501 |
| LLPS-Aon-4183 | Aotus nancymaae | 57.0 | 3e-151 | 450 |
| LLPS-Xim-2565 | Xiphophorus maculatus | 56.98 | 2e-175 | 511 |
| LLPS-Aim-2998 | Ailuropoda melanoleuca | 56.98 | 1e-175 | 511 |
| LLPS-Pap-2495 | Pan paniscus | 56.98 | 5e-176 | 514 |
| LLPS-Poa-1715 | Pongo abelii | 56.98 | 1e-175 | 512 |
| LLPS-Caf-2653 | Canis familiaris | 56.98 | 2e-175 | 511 |
| LLPS-Tag-2419 | Taeniopygia guttata | 56.98 | 3e-176 | 513 |
| LLPS-Pytr-0386 | Pyrenophora triticirepentis | 56.97 | 0.0 | 534 |
| LLPS-Ora-0512 | Ornithorhynchus anatinus | 56.88 | 2e-167 | 489 |
| LLPS-Pyt-0285 | Pyrenophora teres | 56.77 | 0.0 | 533 |
| LLPS-Mum-4029 | Mus musculus | 56.76 | 4e-175 | 510 |
| LLPS-Tar-0840 | Takifugu rubripes | 56.76 | 4e-171 | 500 |
| LLPS-Pof-1399 | Poecilia formosa | 56.76 | 1e-174 | 509 |
| LLPS-Orn-0446 | Oreochromis niloticus | 56.76 | 5e-174 | 508 |
| LLPS-Eqc-2563 | Equus caballus | 56.76 | 2e-175 | 511 |
| LLPS-Mod-3672 | Monodelphis domestica | 56.67 | 1e-174 | 508 |
| LLPS-Phn-0781 | Phaeosphaeria nodorum | 56.63 | 0.0 | 529 |
| LLPS-Lac-0206 | Latimeria chalumnae | 56.58 | 2e-73 | 239 |
| LLPS-Leo-0836 | Lepisosteus oculatus | 56.54 | 5e-174 | 508 |
| LLPS-Asm-3109 | Astyanax mexicanus | 56.54 | 1e-174 | 509 |
| LLPS-Tut-1772 | Tursiops truncatus | 56.54 | 2e-175 | 510 |
| LLPS-Dio-3724 | Dipodomys ordii | 56.54 | 1e-174 | 508 |
| LLPS-Anp-1898 | Anas platyrhynchos | 56.54 | 1e-176 | 514 |
| LLPS-Gag-0273 | Gaeumannomyces graminis | 56.53 | 3e-174 | 508 |
| LLPS-Nec-0746 | Neurospora crassa | 56.46 | 2e-168 | 493 |
| LLPS-Orl-1147 | Oryzias latipes | 56.32 | 1e-173 | 506 |
| LLPS-Loa-1805 | Loxodonta africana | 56.32 | 2e-174 | 508 |
| LLPS-Fia-1484 | Ficedula albicollis | 56.32 | 1e-175 | 511 |
| LLPS-Aso-0519 | Aspergillus oryzae | 56.24 | 1e-177 | 517 |
| LLPS-Asf-0143 | Aspergillus flavus | 56.24 | 1e-177 | 517 |
| LLPS-Blg-0078 | Blumeria graminis | 56.14 | 2e-174 | 509 |
| LLPS-Rhb-0257 | Rhinopithecus bieti | 56.12 | 9e-169 | 493 |
| LLPS-Trv-0049 | Trichoderma virens | 56.06 | 6e-172 | 502 |
| LLPS-Fus-0842 | Fusarium solani | 56.03 | 5e-171 | 499 |
| LLPS-Map-0548 | Magnaporthe poae | 55.91 | 2e-173 | 506 |
| LLPS-Meg-1533 | Meleagris gallopavo | 55.88 | 6e-175 | 508 |
| LLPS-Trr-1019 | Trichoderma reesei | 55.88 | 5e-168 | 489 |
| LLPS-Scj-0486 | Schizosaccharomyces japonicus | 55.8 | 5e-175 | 510 |
| LLPS-Beb-0569 | Beauveria bassiana | 55.8 | 4e-172 | 503 |
| LLPS-Orc-0714 | Oryctolagus cuniculus | 55.65 | 2e-169 | 496 |
| LLPS-Gaga-1251 | Gallus gallus | 55.65 | 2e-174 | 508 |
| LLPS-Lem-1312 | Leptosphaeria maculans | 55.64 | 2e-169 | 521 |
| LLPS-Zyt-0334 | Zymoseptoria tritici | 55.64 | 0.0 | 535 |
| LLPS-Sah-0889 | Sarcophilus harrisii | 55.56 | 3e-173 | 505 |
| LLPS-Asg-0550 | Ashbya gossypii | 55.53 | 2e-164 | 482 |
| LLPS-Tum-1453 | Tuber melanosporum | 55.45 | 2e-176 | 514 |
| LLPS-Cii-0236 | Ciona intestinalis | 55.42 | 2e-169 | 496 |
| LLPS-Pes-2135 | Pelodiscus sinensis | 55.21 | 3e-173 | 505 |
| LLPS-Mao-1400 | Magnaporthe oryzae | 54.69 | 4e-169 | 495 |
| LLPS-Cas-2022 | Carlito syrichta | 54.67 | 3e-163 | 480 |
| LLPS-Kop-0455 | Komagataella pastoris | 54.02 | 1e-159 | 469 |
| LLPS-Xet-1040 | Xenopus tropicalis | 53.74 | 1e-172 | 504 |
| LLPS-Anc-3366 | Anolis carolinensis | 53.3 | 8e-159 | 469 |
| LLPS-Urm-0892 | Ursus maritimus | 52.76 | 8e-147 | 438 |
| LLPS-Otg-1942 | Otolemur garnettii | 49.22 | 5e-136 | 409 |