LLPS-Art-0149
APX3

▼ OVERVIEW

Status: Reviewed
Protein Name: L-ascorbate peroxidase 3
Gene Name: APX3, APX, APXIII, At4g35000, M4E13.60
Ensembl Gene: AT4G35000
Ensembl Protein: AT4G35000.1
Organism: Arabidopsis thaliana
Taxa ID: 3702
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Nucleolus
"...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins."
Arabidopsis thaliana cells26980300

▼ FUNCTION

Plays a key role in hydrogen peroxide removal.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAPIVDAEY  LKEITKARRE  LRSLIANKNC  APIMLRLAWH  DAGTYDAQSK  TGGPNGSIRN  60
61    EEEHTHGANS  GLKIALDLCE  GVKAKHPKIT  YADLYQLAGV  VAVEVTGGPD  IVFVPGRKDS  120
121   NVCPKEGRLP  DAKQGFQHLR  DVFYRMGLSD  KDIVALSGGH  TLGRAHPERS  GFDGPWTQEP  180
181   LKFDNSYFVE  LLKGESEGLL  KLPTDKTLLE  DPEFRRLVEL  YAKDEDAFFR  DYAESHKKLS  240
241   ELGFNPNSSA  GKAVADSTIL  AQSAFGVAVA  AAVVAFGYFY  EIRKRMK  287
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGCAC  CGATTGTTGA  TGCGGAGTAC  TTGAAAGAGA  TCACTAAGGC  TCGCCGTGAG  60
61    CTCCGTTCTC  TCATCGCGAA  CAAGAACTGT  GCTCCTATCA  TGCTCCGATT  GGCATGGCAC  120
121   GATGCTGGAA  CCTATGATGC  TCAATCGAAG  ACCGGTGGAC  CTAATGGCTC  TATCAGGAAC  180
181   GAAGAAGAGC  ACACTCATGG  TGCCAACAGT  GGTTTGAAGA  TCGCTCTCGA  TCTCTGTGAG  240
241   GGCGTGAAAG  CTAAGCATCC  CAAAATCACA  TACGCAGACC  TGTATCAGCT  TGCTGGTGTG  300
301   GTAGCAGTTG  AGGTTACTGG  TGGACCTGAC  ATCGTGTTCG  TTCCCGGGAG  AAAGGATTCA  360
361   AATGTCTGCC  CCAAGGAAGG  AAGACTTCCT  GATGCCAAAC  AAGGTTTCCA  ACATCTCAGA  420
421   GATGTCTTCT  ACCGCATGGG  ACTATCTGAT  AAGGATATTG  TGGCACTCTC  AGGGGGTCAT  480
481   ACTCTGGGAA  GGGCTCACCC  GGAGAGGTCA  GGCTTTGATG  GACCATGGAC  CCAAGAGCCG  540
541   CTGAAGTTTG  ACAACTCCTA  CTTCGTGGAA  CTGCTGAAAG  GAGAATCAGA  GGGCTTGTTG  600
601   AAACTTCCAA  CTGACAAGAC  CTTATTGGAA  GACCCGGAGT  TCCGTCGTCT  TGTTGAGCTT  660
661   TATGCAAAGG  ATGAAGATGC  ATTCTTCAGA  GACTACGCGG  AATCGCACAA  GAAACTCTCT  720
721   GAGCTTGGTT  TCAACCCAAA  CTCCTCAGCA  GGCAAAGCAG  TTGCAGACAG  CACGATTCTG  780
781   GCACAGAGTG  CGTTCGGGGT  TGCAGTTGCT  GCTGCGGTTG  TGGCATTTGG  TTACTTTTAC  840
841   GAGATCCGGA  AGAGGATGAA  GTAA  864

▼ KEYWORD

ID
Family
Acetylation
Calcium
Complete proteome
Glyoxysome
Heme
Hydrogen peroxide
Iron
Membrane
Metal-binding
Oxidoreductase
Peroxidase
Peroxisome
Potassium
Reference proteome
Transmembrane
Transmembrane helix

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Chloroplast envelope
Cellular Component
Glyoxysomal membrane
Cellular Component
Integral component of membrane
Cellular Component
Mitochondrion
Cellular Component
Peroxisomal membrane
Cellular Component
Peroxisome
Cellular Component
Plasmodesma
Cellular Component
Plastid
Cellular Component
Vacuolar membrane
Cellular Component
Vacuole
Molecular Function
Heme binding
Molecular Function
L-ascorbate peroxidase activity
Molecular Function
Metal ion binding
Molecular Function
Peroxidase activity
Biological Process
Cellular response to oxidative stress
Biological Process
Hydrogen peroxide catabolic process
Biological Process
Response to cytokinin
Biological Process
Response to oxidative stress
Biological Process
Response to reactive oxygen species

▼ KEGG


▼ ANNOTATION

Disorder
IUPred2A
Physicochemical
AAindex
Localization
COMPARTMENTS
Expression
ArrayExpress

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0639Arabidopsis lyrata98.260.0 518
LLPS-Bro-2214Brassica oleracea90.942e-175 493
LLPS-Brn-1836Brassica napus90.246e-176 494
LLPS-Brr-2777Brassica rapa89.91e-175 494
LLPS-Sol-0150Solanum lycopersicum85.027e-160 454
LLPS-Gor-1695Gossypium raimondii84.723e-160 455
LLPS-Thc-1732Theobroma cacao84.725e-159 452
LLPS-Sot-0722Solanum tuberosum84.679e-160 454
LLPS-Nia-2248Nicotiana attenuata84.322e-154 454
LLPS-Coc-2111Corchorus capsularis83.978e-156 444
LLPS-Mae-1841Manihot esculenta82.239e-153 436
LLPS-Pot-2395Populus trichocarpa82.171e-152 435
LLPS-Cus-1302Cucumis sativus81.51e-131 381
LLPS-Viv-0807Vitis vinifera80.283e-152 439
LLPS-Via-0565Vigna angularis79.863e-152 435
LLPS-Mua-2272Musa acuminata79.792e-148 425
LLPS-Phv-1967Phaseolus vulgaris79.513e-151 432
LLPS-Zem-1338Zea mays79.443e-138 398
LLPS-Prp-0006Prunus persica79.376e-145 416
LLPS-Glm-1850Glycine max78.821e-149 428
LLPS-Met-0253Medicago truncatula78.121e-149 428
LLPS-Amt-0847Amborella trichopoda77.511e-144 416
LLPS-Sob-2179Sorghum bicolor77.162e-145 417
LLPS-Hea-1645Helianthus annuus77.02e-146 420
LLPS-Sei-1903Setaria italica76.742e-145 417
LLPS-Tra-1775Triticum aestivum76.637e-146 419
LLPS-Hov-0939Hordeum vulgare76.292e-143 416
LLPS-Orp-0349Oryza punctata75.953e-142 409
LLPS-Ors-0682Oryza sativa75.957e-142 409
LLPS-Org-1995Oryza glaberrima75.957e-142 409
LLPS-Orr-1599Oryza rufipogon75.957e-142 409
LLPS-Orni-1262Oryza nivara75.957e-142 409
LLPS-Orb-1977Oryza barthii75.957e-142 409
LLPS-Ori-1291Oryza indica75.957e-142 409
LLPS-Orgl-2366Oryza glumaepatula75.957e-142 409
LLPS-Tru-1149Triticum urartu75.782e-142 409
LLPS-Orbr-1966Oryza brachyantha75.261e-139 403
LLPS-Lep-2310Leersia perrieri75.263e-141 407
LLPS-Brd-2203Brachypodium distachyon75.04e-141 406
LLPS-Orm-1999Oryza meridionalis74.575e-139 401
LLPS-Sem-1866Selaginella moellendorffii71.533e-131 382
LLPS-Php-2139Physcomitrella patens68.122e-128 375
LLPS-Vir-1885Vigna radiata68.052e-140 409
LLPS-Dac-2363Daucus carota67.583e-136 395
LLPS-Put-0393Puccinia triticina48.911e-2194.0
LLPS-Blg-1569Blumeria graminis47.842e-60 202
LLPS-Mel-0997Melampsora laricipopulina47.132e-62 206
LLPS-Abg-1988Absidia glauca46.351e-55 187
LLPS-Gas-0625Galdieria sulphuraria45.852e-64 213
LLPS-Spr-0167Sporisorium reilianum45.671e-59 199
LLPS-Fuo-1569Fusarium oxysporum45.533e-62 207
LLPS-Fuv-0948Fusarium verticillioides45.532e-62 207
LLPS-Chr-0061Chlamydomonas reinhardtii45.491e-59 199
LLPS-Miv-1060Microbotryum violaceum44.621e-63 209
LLPS-Dos-1250Dothistroma septosporum42.039e-62 204
LLPS-Osl-1470Ostreococcus lucimarinus41.39e-48 167
LLPS-Yal-0181Yarrowia lipolytica39.384e-51 176
LLPS-Kop-1379Komagataella pastoris35.137e-45 162
LLPS-Sac-1541Saccharomyces cerevisiae34.632e-41 152