LLPS-Art-0056
CARA
▼ OVERVIEW
| Status: | Reviewed |
| Protein Name: | Carbamoyl-phosphate synthase small chain, chloroplastic; Carbamoyl-phosphate synthetase glutamine chain; Protein VENOSA 6 |
| Gene Name: | CARA, VEN6, At3g27740, MGF10.15 |
| Ensembl Gene: | AT3G27740 |
| Ensembl Protein: | AT3G27740.2 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Description | Tissue/Cell | PMIDs |
|---|---|---|---|
| Nucleolus | "...We identified 1602 proteins in the nucleolar and 2544 proteins in the nuclear fraction with an overlap of 1429 proteins." | Arabidopsis thaliana cells | 26980300 |
▼ FUNCTION
| Involved in arginine biosynthesis. Required for mesophyll development. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT3G27740.2 | AT3G27740.2 |
| Ensembl | AT3G27740.1 | AT3G27740.1 |
| UniProt | Q9LVW7, CARA_ARATH, O24447 | |
| GeneBank | AB018114, AY079315, CP002686, AY046004, U73175 | AEE77358.1, BAB02698.1, AAC25961.1, AAL85046.1, AAK76678.1 |
| RefSeq | NM_113690.3 | NP_566824.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAMATRTLGF VLPTSLSSQP SFDRRGGGFR VSVIRCSTSP LTFPTSGVVE KPWTSYNARL 60 61 VLEDGSIWPA KSFGAPGTRI AELVFNTSLT GYQEILTDPS YAGQFVLMTN PQIGNTGVNP 120 121 DDEESGQCFL TGLVIRNLSI STSNWRCTKT LADYLTERDI MGVYDLDTRA ITRRLREDGS 180 181 LIGVLSTEQS KTDDELLQMS RSWDIVGIDL ISDVSCKSPY EWVDKTNAEW DFNTNSRDGK 240 241 SYKVIAYDFG IKQNILRRLS SYGCQITVVP STFPAAEALK MNPDGILFSN GPGDPSAVPY 300 301 AVETVKELLG KVPVYGICMG HQLLGQALGG KTFKMKFGHH GGNHPVRNNR TGQVEISAQN 360 361 HNYAVDPASL PGGVEVTHVN LNDGSCAGLS FPEMNVMSLQ YHPEASPGPH DSDNAFREFI 420 421 ELMKRSKQSS 430 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCATGG CAACAAGGAC TCTAGGCTTT GTTTTGCCTA CGAGCTTATC TTCCCAGCCT 60 61 TCCTTCGACC GTCGCGGCGG TGGATTTAGG GTTTCTGTCA TCCGTTGCTC CACTTCTCCA 120 121 CTCACTTTTC CCACTTCTGG TGTTGTGGAG AAACCTTGGA CTTCGTACAA TGCTAGGCTT 180 181 GTGTTAGAAG ATGGTTCTAT CTGGCCTGCT AAGTCTTTTG GTGCTCCTGG AACCCGTATT 240 241 GCTGAATTGG TGTTTAACAC TTCCTTGACA GGGTATCAAG AAATTTTAAC TGATCCTAGT 300 301 TATGCTGGGC AGTTTGTGCT AATGACAAAC CCACAAATTG GTAATACTGG TGTCAATCCT 360 361 GATGATGAAC TTCTGCAAAT GTCTCGTTCA TGGGATATCG TAGGTATTGA TCTAATAAGT 420 421 GATGTTTCAT GTAAATCTCC CTATGAATGG GTTGACAAAA CAAACGCTGA ATGGGATTTC 480 481 AACACGAATT CACGAGATGG GAAATCCTAC AAAGTTATTG CTTACGATTT TGGAATCAAG 540 541 CAAAACATCC TAAGACGCCT TTCATCTTAC GGATGTCAAA TCACTGTTGT TCCGTCCACA 600 601 TTTCCAGCTG CCGAGGCGCT GAAAATGAAT CCAGATGGGA TTTTGTTCAG CAACGGTCCT 660 661 GGAGACCCTT CTGCTGTGCC ATATGCTGTT GAGACAGTTA AAGAGCTTCT CGGTAAAGTC 720 721 CCTGTTTACG GAATCTGTAT GGGCCATCAG TTGCTTGGTC AAGCTTTGGG GGGTAAAACC 780 781 TTCAAGATGA AGTTTGGTCA TCATGGAGGA AACCACCCAG TTCGTAACAA CAGAACTGGT 840 841 CAGGTGGAGA TCAGTGCTCA GAATCACAAC TATGCGGTTG ATCCAGCTTC ACTTCCCGGA 900 901 GGCGTAGAAG TAACACATGT CAATCTCAAT GATGGAAGCT GTGCGGGTCT ATCTTTCCCG 960 961 GAAATGAATG TTATGTCACT CCAGTACCAC CCTGAAGCCT CCCCTGGACC TCACGACTCT 1020 1021 GATAACGCAT TTAGAGAGTT CATAGAGCTT ATGAAGAGAT CGAAACAAAG CTCCTGA 1077 |
▼ KEYWORD
ID | Family |
Alternative splicing | |
Amino-acid biosynthesis | |
Arginine biosynthesis | |
ATP-binding | |
Chloroplast | |
Complete proteome | |
Glutamine amidotransferase | |
Ligase | |
Nucleotide-binding | |
Plastid | |
Pyrimidine biosynthesis | |
Reference proteome | |
Transit peptide
|
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Carbamoyl-phosphate synthase complex | |
Cellular Component | Chloroplast | |
Cellular Component | Chloroplast stroma | |
Cellular Component | Cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | 'de novo' UMP biosynthetic process | |
Biological Process | Arginine biosynthetic process | |
Biological Process | Cellular response to phosphate starvation | |
Biological Process | Glutamine metabolic process | |
Biological Process | Nitrogen compound metabolic process |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| PTM | ||||
| PLMD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-2108 | Arabidopsis lyrata | 98.6 | 0.0 | 882 |
| LLPS-Brr-0532 | Brassica rapa | 91.1 | 0.0 | 802 |
| LLPS-Bro-2973 | Brassica oleracea | 90.89 | 0.0 | 806 |
| LLPS-Brn-3083 | Brassica napus | 90.19 | 0.0 | 803 |
| LLPS-Gor-2483 | Gossypium raimondii | 79.46 | 0.0 | 687 |
| LLPS-Pot-2115 | Populus trichocarpa | 79.21 | 0.0 | 676 |
| LLPS-Mae-1505 | Manihot esculenta | 79.0 | 0.0 | 671 |
| LLPS-Thc-0898 | Theobroma cacao | 77.97 | 0.0 | 668 |
| LLPS-Hea-2236 | Helianthus annuus | 77.56 | 0.0 | 673 |
| LLPS-Mua-2432 | Musa acuminata | 77.11 | 0.0 | 647 |
| LLPS-Coc-1985 | Corchorus capsularis | 76.37 | 0.0 | 684 |
| LLPS-Viv-2204 | Vitis vinifera | 75.7 | 0.0 | 686 |
| LLPS-Nia-1645 | Nicotiana attenuata | 75.6 | 0.0 | 673 |
| LLPS-Prp-0269 | Prunus persica | 75.06 | 0.0 | 677 |
| LLPS-Orgl-0721 | Oryza glumaepatula | 74.14 | 0.0 | 623 |
| LLPS-Ori-0764 | Oryza indica | 74.14 | 0.0 | 624 |
| LLPS-Sot-1621 | Solanum tuberosum | 74.13 | 0.0 | 676 |
| LLPS-Orr-0021 | Oryza rufipogon | 73.88 | 0.0 | 623 |
| LLPS-Brd-2404 | Brachypodium distachyon | 73.72 | 0.0 | 640 |
| LLPS-Glm-2423 | Glycine max | 73.71 | 0.0 | 652 |
| LLPS-Orbr-0765 | Oryza brachyantha | 73.61 | 0.0 | 618 |
| LLPS-Orb-0666 | Oryza barthii | 73.44 | 0.0 | 523 |
| LLPS-Phv-2381 | Phaseolus vulgaris | 73.29 | 0.0 | 665 |
| LLPS-Met-1909 | Medicago truncatula | 73.13 | 0.0 | 666 |
| LLPS-Dac-1020 | Daucus carota | 72.95 | 0.0 | 650 |
| LLPS-Cus-0081 | Cucumis sativus | 72.94 | 0.0 | 663 |
| LLPS-Via-0070 | Vigna angularis | 72.83 | 0.0 | 660 |
| LLPS-Tra-2245 | Triticum aestivum | 72.66 | 0.0 | 627 |
| LLPS-Vir-0839 | Vigna radiata | 72.54 | 0.0 | 656 |
| LLPS-Hov-1244 | Hordeum vulgare | 72.41 | 0.0 | 625 |
| LLPS-Amt-2077 | Amborella trichopoda | 70.23 | 0.0 | 639 |
| LLPS-Zem-1307 | Zea mays | 69.73 | 0.0 | 622 |
| LLPS-Sob-1502 | Sorghum bicolor | 69.73 | 0.0 | 621 |
| LLPS-Tru-0740 | Triticum urartu | 69.49 | 0.0 | 617 |
| LLPS-Sem-0742 | Selaginella moellendorffii | 69.35 | 0.0 | 578 |
| LLPS-Php-1858 | Physcomitrella patens | 69.25 | 0.0 | 613 |
| LLPS-Orm-1055 | Oryza meridionalis | 69.23 | 0.0 | 607 |
| LLPS-Ors-0332 | Oryza sativa | 69.21 | 0.0 | 609 |
| LLPS-Orni-2364 | Oryza nivara | 68.98 | 0.0 | 605 |
| LLPS-Lep-0911 | Leersia perrieri | 68.84 | 0.0 | 618 |
| LLPS-Sei-1982 | Setaria italica | 68.78 | 0.0 | 625 |
| LLPS-Orp-1895 | Oryza punctata | 68.56 | 0.0 | 622 |
| LLPS-Sol-0210 | Solanum lycopersicum | 65.17 | 0.0 | 594 |
| LLPS-Osl-0352 | Ostreococcus lucimarinus | 61.58 | 0.0 | 521 |
| LLPS-Chr-0106 | Chlamydomonas reinhardtii | 59.21 | 0.0 | 530 |
| LLPS-Chc-0151 | Chondrus crispus | 42.82 | 3e-102 | 317 |
| LLPS-Cym-0002 | Cyanidioschyzon merolae | 41.29 | 3e-87 | 277 |
| LLPS-Cap-1510 | Cavia porcellus | 38.89 | 6e-67 | 238 |
| LLPS-Ict-3045 | Ictidomys tridecemlineatus | 38.32 | 3e-67 | 239 |
| LLPS-Dio-0133 | Dipodomys ordii | 38.06 | 5e-65 | 233 |
| LLPS-Mea-2336 | Mesocricetus auratus | 38.06 | 1e-66 | 238 |
| LLPS-Ran-1445 | Rattus norvegicus | 37.99 | 6e-66 | 236 |
| LLPS-Poa-0397 | Pongo abelii | 37.96 | 3e-66 | 236 |
| LLPS-Nol-2230 | Nomascus leucogenys | 37.96 | 2e-66 | 237 |
| LLPS-Man-2956 | Macaca nemestrina | 37.96 | 3e-65 | 233 |
| LLPS-Rhb-1521 | Rhinopithecus bieti | 37.96 | 1e-65 | 235 |
| LLPS-Mal-2322 | Mandrillus leucophaeus | 37.96 | 2e-65 | 234 |
| LLPS-Paa-4238 | Papio anubis | 37.96 | 1e-65 | 234 |
| LLPS-Chs-1809 | Chlorocebus sabaeus | 37.96 | 4e-66 | 236 |
| LLPS-Maf-1923 | Macaca fascicularis | 37.96 | 4e-65 | 233 |
| LLPS-Aon-2296 | Aotus nancymaae | 37.96 | 4e-66 | 236 |
| LLPS-Cea-0715 | Cercocebus atys | 37.96 | 1e-65 | 234 |
| LLPS-Caj-0930 | Callithrix jacchus | 37.96 | 2e-66 | 237 |
| LLPS-Mum-3801 | Mus musculus | 37.8 | 4e-66 | 236 |
| LLPS-Hos-0707 | Homo sapiens | 37.7 | 1e-65 | 235 |
| LLPS-Pat-0188 | Pan troglodytes | 37.56 | 1e-63 | 229 |
| LLPS-Pap-0416 | Pan paniscus | 37.56 | 4e-64 | 230 |
| LLPS-Orc-0421 | Oryctolagus cuniculus | 37.5 | 1e-64 | 231 |
| LLPS-Bot-3395 | Bos taurus | 37.43 | 1e-62 | 226 |
| LLPS-Nec-1189 | Neurospora crassa | 37.43 | 3e-69 | 233 |
| LLPS-Ved-0994 | Verticillium dahliae | 37.4 | 8e-61 | 221 |
| LLPS-Aim-1760 | Ailuropoda melanoleuca | 37.4 | 2e-63 | 229 |
| LLPS-Mup-2860 | Mustela putorius furo | 37.34 | 2e-63 | 228 |
| LLPS-Scj-0917 | Schizosaccharomyces japonicus | 37.34 | 1e-68 | 243 |
| LLPS-Gog-1948 | Gorilla gorilla | 37.31 | 2e-62 | 225 |
| LLPS-Scs-1021 | Sclerotinia sclerotiorum | 37.28 | 3e-71 | 238 |
| LLPS-Leo-0399 | Lepisosteus oculatus | 37.18 | 5e-67 | 238 |
| LLPS-Otg-4164 | Otolemur garnettii | 37.17 | 9e-65 | 232 |
| LLPS-Sus-0043 | Sus scrofa | 37.17 | 3e-62 | 225 |
| LLPS-Caf-1555 | Canis familiaris | 36.98 | 9e-64 | 229 |
| LLPS-Fec-1965 | Felis catus | 36.98 | 4e-63 | 228 |
| LLPS-Trr-0985 | Trichoderma reesei | 36.84 | 2e-68 | 243 |
| LLPS-Scc-1458 | Schizosaccharomyces cryophilus | 36.84 | 1e-66 | 238 |
| LLPS-Eqc-2295 | Equus caballus | 36.81 | 9e-64 | 229 |
| LLPS-Ova-4287 | Ovis aries | 36.65 | 1e-55 | 206 |
| LLPS-Trv-1082 | Trichoderma virens | 36.64 | 8e-71 | 237 |
| LLPS-Kop-0624 | Komagataella pastoris | 36.64 | 1e-67 | 241 |
| LLPS-Mod-0175 | Monodelphis domestica | 36.62 | 2e-64 | 231 |
| LLPS-Lac-1209 | Latimeria chalumnae | 36.59 | 6e-54 | 201 |
| LLPS-Scp-1181 | Schizosaccharomyces pombe | 36.56 | 3e-68 | 242 |
| LLPS-Scf-2912 | Scleropages formosus | 36.54 | 6e-68 | 241 |
| LLPS-Pof-1994 | Poecilia formosa | 36.53 | 8e-63 | 226 |
| LLPS-Xim-0323 | Xiphophorus maculatus | 36.53 | 4e-65 | 233 |
| LLPS-Loa-1680 | Loxodonta africana | 36.46 | 5e-57 | 209 |
| LLPS-Myl-2198 | Myotis lucifugus | 36.46 | 1e-63 | 229 |
| LLPS-Orl-3507 | Oryzias latipes | 36.46 | 5e-63 | 224 |
| LLPS-Asn-0661 | Aspergillus nidulans | 36.46 | 4e-66 | 224 |
| LLPS-Pyt-0466 | Pyrenophora teres | 36.39 | 1e-62 | 224 |
| LLPS-Asg-1283 | Ashbya gossypii | 36.34 | 9e-68 | 227 |
| LLPS-Fia-1893 | Ficedula albicollis | 36.31 | 3e-50 | 189 |
| LLPS-Orn-3404 | Oreochromis niloticus | 36.29 | 2e-63 | 228 |
| LLPS-Scm-2970 | Scophthalmus maximus | 36.27 | 9e-65 | 231 |
| LLPS-Dos-0004 | Dothistroma septosporum | 36.25 | 5e-71 | 238 |
| LLPS-Gas-1183 | Galdieria sulphuraria | 36.25 | 1e-85 | 274 |
| LLPS-Fud-2853 | Fukomys damarensis | 36.24 | 4e-57 | 209 |
| LLPS-Pytr-0073 | Pyrenophora triticirepentis | 36.22 | 8e-66 | 223 |
| LLPS-Fus-0357 | Fusarium solani | 36.22 | 7e-64 | 229 |
| LLPS-Asfu-0873 | Aspergillus fumigatus | 36.2 | 5e-65 | 221 |
| LLPS-Nef-0818 | Neosartorya fischeri | 36.2 | 1e-65 | 223 |
| LLPS-Fuv-0618 | Fusarium verticillioides | 36.2 | 6e-64 | 229 |
| LLPS-Phn-0764 | Phaeosphaeria nodorum | 36.18 | 1e-67 | 229 |
| LLPS-Sac-0183 | Saccharomyces cerevisiae | 36.14 | 1e-67 | 241 |
| LLPS-Sah-3261 | Sarcophilus harrisii | 36.13 | 3e-62 | 225 |
| LLPS-Asni-0654 | Aspergillus niger | 36.13 | 3e-64 | 219 |
| LLPS-Yal-0616 | Yarrowia lipolytica | 36.1 | 9e-68 | 241 |
| LLPS-Cog-0074 | Colletotrichum gloeosporioides | 36.06 | 2e-70 | 236 |
| LLPS-Coo-0698 | Colletotrichum orbiculare | 36.06 | 1e-68 | 231 |
| LLPS-Mao-1228 | Magnaporthe oryzae | 35.97 | 3e-65 | 234 |
| LLPS-Fuo-0355 | Fusarium oxysporum | 35.95 | 9e-63 | 226 |
| LLPS-Tum-1143 | Tuber melanosporum | 35.92 | 3e-63 | 228 |
| LLPS-Icp-1708 | Ictalurus punctatus | 35.84 | 8e-64 | 229 |
| LLPS-Dar-3728 | Danio rerio | 35.82 | 2e-64 | 230 |
| LLPS-Lem-0015 | Leptosphaeria maculans | 35.82 | 3e-66 | 226 |
| LLPS-Cogr-0620 | Colletotrichum graminicola | 35.81 | 1e-69 | 234 |
| LLPS-Asm-2368 | Astyanax mexicanus | 35.75 | 1e-66 | 237 |
| LLPS-Aso-1083 | Aspergillus oryzae | 35.68 | 2e-65 | 222 |
| LLPS-Asf-0066 | Aspergillus flavus | 35.68 | 2e-65 | 222 |
| LLPS-Miv-0025 | Microbotryum violaceum | 35.64 | 1e-60 | 209 |
| LLPS-Map-0350 | Magnaporthe poae | 35.62 | 6e-66 | 223 |
| LLPS-Asc-1256 | Aspergillus clavatus | 35.6 | 3e-63 | 217 |
| LLPS-Blg-0107 | Blumeria graminis | 35.48 | 2e-67 | 228 |
| LLPS-Drm-0934 | Drosophila melanogaster | 35.46 | 2e-61 | 223 |
| LLPS-Gag-0768 | Gaeumannomyces graminis | 35.37 | 4e-66 | 225 |
| LLPS-Abg-0613 | Absidia glauca | 35.31 | 4e-64 | 218 |
| LLPS-Ast-0801 | Aspergillus terreus | 35.28 | 9e-65 | 232 |
| LLPS-Anc-1440 | Anolis carolinensis | 35.14 | 2e-59 | 216 |
| LLPS-Gaa-1956 | Gasterosteus aculeatus | 34.81 | 2e-59 | 216 |
| LLPS-Mam-0107 | Macaca mulatta | 34.61 | 4e-61 | 221 |
| LLPS-Spr-1111 | Sporisorium reilianum | 34.51 | 7e-62 | 224 |
| LLPS-Cas-2291 | Carlito syrichta | 34.33 | 1e-60 | 219 |
| LLPS-Beb-1496 | Beauveria bassiana | 34.27 | 1e-62 | 226 |
| LLPS-Pug-0561 | Puccinia graminis | 34.17 | 5e-63 | 216 |
| LLPS-Tar-0645 | Takifugu rubripes | 34.15 | 1e-63 | 228 |
| LLPS-Ten-1590 | Tetraodon nigroviridis | 34.11 | 1e-59 | 217 |
| LLPS-Put-0496 | Puccinia triticina | 34.09 | 2e-62 | 214 |
| LLPS-Zyt-0003 | Zymoseptoria tritici | 34.01 | 4e-69 | 232 |
| LLPS-Gaga-0437 | Gallus gallus | 33.78 | 8e-58 | 211 |
| LLPS-Anp-1126 | Anas platyrhynchos | 33.74 | 2e-64 | 230 |
| LLPS-Mel-0380 | Melampsora laricipopulina | 33.57 | 2e-58 | 214 |
| LLPS-Usm-1285 | Ustilago maydis | 33.56 | 3e-63 | 218 |
| LLPS-Tag-0988 | Taeniopygia guttata | 33.24 | 1e-54 | 202 |
| LLPS-Meg-0593 | Meleagris gallopavo | 33.01 | 1e-61 | 223 |
| LLPS-Crn-1390 | Cryptococcus neoformans | 32.65 | 7e-56 | 206 |
| LLPS-Cae-1071 | Caenorhabditis elegans | 32.65 | 6e-58 | 212 |
| LLPS-Xet-1012 | Xenopus tropicalis | 32.01 | 4e-62 | 224 |