LLPS-Aon-a1193
ATP2B4
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Calcium-transporting ATPase |
| Gene Name: | ATP2B4 |
| Ensembl Gene: | ENSANAG00000033579.1 |
| Ensembl Protein: | ENSANAP00000031725.1 |
| Organism: | Aotus nancymaae |
| Taxa ID: | 37293 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSANAT00000049770.1 | ENSANAP00000031725.1 |
| Ensembl | ENSANAT00000049774.1 | ENSANAP00000031729.1 |
| UniProt | A0A2K5EEU7, A0A2K5EEU7_AOTNA |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 ADLEKRRQVF GHNVIPPKKP KTFLELVWEA LQDVTLIILE IAAIISLVLS FYRPAGEENE 60 61 LCGQVATAPE DENEAQAGWI EGAAILFSVI IVVLVTAFND WSKEKQFRGL QSRIEQEQKF 120 121 SVIRNGQLIQ LPVAEIVVGD IAQVKYGDLL PADGVLIQGN DLKIDESSLT GESDHVKKSL 180 181 EKDPMLLSGT HVMEGSGRMV VTAVGVNSQT GIILTLLGVN EDDEGEKKKK GKKQGVPENR 240 241 NKAKTQDGVA LEIQPLNSQE GTDNEEKEKK AVKVPKKEKS VLQGKLTRLA VQIGKAGLIM 300 301 SALTVFILIL YFVIDNFVIN RRPWLPECTP IYIQYFVKFF IIGVTVLVVA VPEGLPLAVT 360 361 ISLAYSVKKM MKDNNLVRHL DACETMGNAT AICSDKTGTL TMNRMTVVQA YIGGIHYRQI 420 421 PSPDVFLPKV LDLIVNGISI NSAYTSKILV SIAFGRIPGS QWRMCIRDRP SWDNENEILT 480 481 ELTCIAVVGI EDPVRPEVPD AIAKCKQAGI TVRMVTGDNI NTARAIATKC GILTPGDDFL 540 541 CLEGKEFNRL IRNEKGEVEQ EKLDKIWPKL RVLARSSPTD KHTLVKGIID STVGEHRQVV 600 601 AVTGDGTNDG PALKKADVGF AMGIAGTDVA KEASDIILTD DNFTSIVKAV MWGRNVYDSI 660 661 SKFLQFQLTV NVVAVIVAFT GACITQDSPL KAVQMLWVNL IMDTFASLAL ATEPPTESLL 720 721 KRRPYGRNKP LISRTMMKNI LGHAFYQLIV IFILVFAGEK FFDIDSGRKA PLHSPPTQHY 780 781 TIVFNTFVLM QLFNEINSRK IHGEKNVFSG IYRNVIFCAV VLGTFICQIF IVEFGGKPFS 840 841 CTRLSLSQWL WCLFIGIGEL LWGQIISAIP TRSLKFLKEA GHGTTKEEIT KDAEGLDEID 900 901 HAEMELRRGQ ILWFRGLNRI QTQIKVVKAF HSSLHESIQK PYNQNSIHNF MTHPEFAIDE 960 961 ELPRTPLLDE EEEENPDKAS NFGTRVLLLD GEVTAHANTN NNAVGCNQVQ ISHADSPLQS 1020 1021 LETSV 1025 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Integral component of membrane | |
Cellular Component | Sperm flagellum | |
Cellular Component | T-tubule | |
Cellular Component | Z disc | |
Molecular Function | ATP binding | |
Molecular Function | Calcium-transporting ATPase activity | |
Molecular Function | Calmodulin binding | |
Molecular Function | Nitric-oxide synthase binding | |
Molecular Function | Nitric-oxide synthase inhibitor activity | |
Molecular Function | Protein phosphatase 2B binding | |
Biological Process | Cellular calcium ion homeostasis | |
Biological Process | Cellular response to acetylcholine | |
Biological Process | Cellular response to epinephrine stimulus | |
Biological Process | Flagellated sperm motility | |
Biological Process | Negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | |
Biological Process | Negative regulation of arginine catabolic process | |
Biological Process | Negative regulation of calcineurin-NFAT signaling cascade | |
Biological Process | Negative regulation of cardiac muscle hypertrophy in response to stress | |
Biological Process | Negative regulation of citrulline biosynthetic process | |
Biological Process | Negative regulation of nitric oxide biosynthetic process | |
Biological Process | Negative regulation of nitric oxide mediated signal transduction | |
Biological Process | Negative regulation of nitric-oxide synthase activity | |
Biological Process | Negative regulation of the force of heart contraction | |
Biological Process | Positive regulation of cAMP-dependent protein kinase activity | |
Biological Process | Positive regulation of peptidyl-serine phosphorylation | |
Biological Process | Regulation of cell cycle G1/S phase transition | |
Biological Process | Regulation of transcription by RNA polymerase II | |
Biological Process | Response to hydrostatic pressure | |
Biological Process | Urinary bladder smooth muscle contraction |