• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Anc-2715
CNOT8

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: CNOT8
Ensembl Gene: ENSACAG00000004001.3
Ensembl Protein: ENSACAP00000003923.2
Organism: Anolis carolinensis
Taxa ID: 28377
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Stress granulePredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPAALAENSQ  VICEVWANNL  EEEMRKIREI  VLSYSYIAMD  TEFPGVVVRP  IGEFRSSIDY  60
61    QYQLLRCNVD  LLKIIQLGLT  FTNEKGEYPA  GINTWQFNFK  FNLTEDMYSQ  DSIDLLASSG  120
121   LQFQKHEEEG  IDTLHFAELL  MTSGVVLCDN  VKWLSFHSGY  DFGYMVKLLT  DSRLPEEEHE  180
181   FFHILNLFFP  SIYDVKYLMK  SCKNLKGGLQ  EVADQLDLQR  IGRQHQAGSD  SLLTGMAFFR  240
241   MKELFFEDTI  DDAKYCGRLY  GLGTGVAQKQ  SEDVETAQEK  MSILAIINNM  QQ  292
Nucleotide CDS Sequence (FASTA)
1     ATGCCAGCAG  CACTTGCAGA  AAATAGTCAG  GTGATCTGTG  AAGTATGGGC  AAACAATCTA  60
61    GAAGAAGAGA  TGAGGAAAAT  TCGGGAAATT  GTTCTCAGCT  ACAGCTACAT  TGCAATGGAT  120
121   ACAGAGTTTC  CTGGAGTTGT  GGTTCGGCCA  ATAGGTGAAT  TCCGTAGCTC  TATAGACTAC  180
181   CAGTACCAGC  TTCTCCGGTG  TAATGTTGAC  CTCTTAAAGA  TTATCCAGCT  AGGACTGACC  240
241   TTCACAAATG  AAAAAGGAGA  ATATCCTGCT  GGAATCAACA  CTTGGCAGTT  TAACTTCAAA  300
301   TTCAATCTTA  CGGAAGATAT  GTATTCTCAG  GATTCAATAG  ATCTTCTTGC  AAGCTCTGGA  360
361   CTGCAGTTCC  AGAAACATGA  GGAGGAAGGA  ATTGATACTT  TGCATTTTGC  AGAGCTACTT  420
421   ATGACTTCTG  GTGTGGTGCT  TTGTGACAAT  GTCAAGTGGC  TTTCATTTCA  CAGTGGCTAT  480
481   GACTTTGGTT  ATATGGTGAA  ACTTCTGACA  GATTCAAGGC  TTCCCGAAGA  AGAACATGAA  540
541   TTCTTTCATA  TCTTGAATCT  CTTCTTCCCA  TCCATATATG  ACGTTAAGTA  CCTGATGAAG  600
601   AGTTGCAAAA  ACCTAAAGGG  AGGCCTCCAA  GAAGTGGCCG  ACCAGCTAGA  TTTGCAGCGG  660
661   ATTGGACGAC  AGCACCAAGC  CGGATCAGAC  TCGCTACTTA  CAGGGATGGC  ATTTTTCAGG  720
721   ATGAAAGAGT  TGTTCTTTGA  GGATACAATC  GATGATGCAA  AGTACTGTGG  GAGACTGTAT  780
781   GGCCTTGGCA  CAGGAGTAGC  TCAGAAACAG  AGTGAAGATG  TAGAAACAGC  ACAAGAGAAA  840
841   ATGAGTATTT  TGGCGATTAT  CAATAATATG  CAGCAGTGA  879

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gaga-0765Gallus gallus97.940.0 595
LLPS-Rhb-4261Rhinopithecus bieti97.941e-176 495
LLPS-Fia-1930Ficedula albicollis97.940.0 595
LLPS-Meg-1374Meleagris gallopavo97.940.0 595
LLPS-Anp-0096Anas platyrhynchos97.590.0 592
LLPS-Poa-1087Pongo abelii97.562e-178 501
LLPS-Cas-1503Carlito syrichta97.260.0 596
LLPS-Mam-1825Macaca mulatta97.260.0 596
LLPS-Eqc-2765Equus caballus97.260.0 596
LLPS-Caf-2639Canis familiaris97.260.0 596
LLPS-Orc-0042Oryctolagus cuniculus97.260.0 596
LLPS-Loa-0041Loxodonta africana97.260.0 596
LLPS-Man-1709Macaca nemestrina97.260.0 596
LLPS-Mod-0575Monodelphis domestica97.260.0 595
LLPS-Fec-0669Felis catus97.260.0 596
LLPS-Pap-1183Pan paniscus97.260.0 596
LLPS-Urm-0300Ursus maritimus97.260.0 596
LLPS-Pat-0574Pan troglodytes97.260.0 596
LLPS-Hos-0060Homo sapiens97.260.0 596
LLPS-Ova-0090Ovis aries97.260.0 596
LLPS-Myl-2560Myotis lucifugus97.260.0 596
LLPS-Aim-0923Ailuropoda melanoleuca97.260.0 596
LLPS-Mup-1918Mustela putorius furo97.260.0 596
LLPS-Paa-0566Papio anubis97.260.0 596
LLPS-Mal-0022Mandrillus leucophaeus97.260.0 596
LLPS-Bot-0684Bos taurus97.260.0 596
LLPS-Tut-0865Tursiops truncatus97.260.0 596
LLPS-Caj-0449Callithrix jacchus97.260.0 596
LLPS-Fud-1800Fukomys damarensis97.260.0 596
LLPS-Gog-0384Gorilla gorilla97.260.0 596
LLPS-Cea-2040Cercocebus atys97.260.0 596
LLPS-Sus-2759Sus scrofa97.260.0 596
LLPS-Chs-0769Chlorocebus sabaeus97.260.0 596
LLPS-Maf-2798Macaca fascicularis97.260.0 596
LLPS-Cap-1889Cavia porcellus96.920.0 594
LLPS-Ora-2430Ornithorhynchus anatinus96.920.0 594
LLPS-Mum-0556Mus musculus96.920.0 593
LLPS-Ran-3698Rattus norvegicus96.580.0 593
LLPS-Dio-3823Dipodomys ordii96.580.0 592
LLPS-Tag-2490Taeniopygia guttata96.220.0 586
LLPS-Sah-0385Sarcophilus harrisii95.210.0 585
LLPS-Xet-1622Xenopus tropicalis90.351e-172 486
LLPS-Tar-1047Takifugu rubripes86.720.0 508
LLPS-Nol-2702Nomascus leucogenys86.640.0 512
LLPS-Ten-0018Tetraodon nigroviridis86.084e-179 503
LLPS-Leo-2934Lepisosteus oculatus85.360.0 513
LLPS-Scf-2181Scleropages formosus84.950.0 508
LLPS-Aon-0023Aotus nancymaae84.594e-179 501
LLPS-Dar-0049Danio rerio84.40.0 511
LLPS-Gaa-1621Gasterosteus aculeatus84.194e-172 486
LLPS-Asm-3090Astyanax mexicanus84.040.0 510
LLPS-Pof-2354Poecilia formosa83.935e-180 505
LLPS-Icp-1105Ictalurus punctatus83.930.0 508
LLPS-Scm-2327Scophthalmus maximus83.577e-179 506
LLPS-Xim-3037Xiphophorus maculatus83.572e-179 504
LLPS-Orn-0209Oreochromis niloticus83.330.0 508
LLPS-Otg-3197Otolemur garnettii82.943e-176 496
LLPS-Ere-0231Erinaceus europaeus79.317e-132 381
LLPS-Ict-4290Ictidomys tridecemlineatus78.231e-162 461
LLPS-Pes-3367Pelodiscus sinensis78.231e-162 461
LLPS-Mea-3199Mesocricetus auratus78.231e-162 461
LLPS-Lac-1707Latimeria chalumnae77.863e-162 460
LLPS-Orl-1620Oryzias latipes77.122e-161 458
LLPS-Drm-1422Drosophila melanogaster71.674e-128 376
LLPS-Cii-0703Ciona intestinalis67.73e-135 391
LLPS-Cis-0538Ciona savignyi67.542e-138 400
LLPS-Abg-1348Absidia glauca64.622e-124 365
LLPS-Miv-0374Microbotryum violaceum60.774e-116 346
LLPS-Spr-1228Sporisorium reilianum59.141e-114 340
LLPS-Gas-0169Galdieria sulphuraria59.01e-112 335
LLPS-Put-0376Puccinia triticina58.783e-113 338
LLPS-Usm-1136Ustilago maydis58.755e-114 339
LLPS-Mel-0287Melampsora laricipopulina58.572e-111 333
LLPS-Pug-0324Puccinia graminis58.42e-112 336
LLPS-Php-0755Physcomitrella patens57.756e-103 309
LLPS-Prp-0696Prunus persica56.23e-100 302
LLPS-Nia-0813Nicotiana attenuata56.22e-97 295
LLPS-Crn-0915Cryptococcus neoformans56.152e-107 321
LLPS-Sem-0303Selaginella moellendorffii55.564e-96 291
LLPS-Gor-0757Gossypium raimondii55.346e-100 301
LLPS-Sot-0427Solanum tuberosum54.961e-97 295
LLPS-Thc-1592Theobroma cacao54.968e-98 296
LLPS-Sol-1092Solanum lycopersicum54.962e-97 295
LLPS-Amt-1461Amborella trichopoda54.852e-99 300
LLPS-Tum-0981Tuber melanosporum54.845e-112 339
LLPS-Dac-0796Daucus carota54.652e-98 297
LLPS-Chr-0426Chlamydomonas reinhardtii54.232e-96 292
LLPS-Pot-0055Populus trichocarpa54.014e-101 304
LLPS-Viv-0123Vitis vinifera53.995e-97 294
LLPS-Mae-0732Manihot esculenta53.91e-98 298
LLPS-Hea-2292Helianthus annuus53.882e-96 292
LLPS-Phv-0336Phaseolus vulgaris53.552e-100 303
LLPS-Coc-0890Corchorus capsularis53.443e-93 284
LLPS-Glm-1937Glycine max53.266e-100 301
LLPS-Cus-0227Cucumis sativus53.211e-95 290
LLPS-Bro-2636Brassica oleracea53.116e-97 293
LLPS-Brn-1383Brassica napus53.113e-97 294
LLPS-Vir-0082Vigna radiata53.014e-95 289
LLPS-Scp-1496Schizosaccharomyces pombe52.961e-94 290
LLPS-Via-0336Vigna angularis52.861e-100 303
LLPS-Osl-0875Ostreococcus lucimarinus52.811e-97 295
LLPS-Brr-0737Brassica rapa52.754e-96 291
LLPS-Lep-1539Leersia perrieri52.711e-95 291
LLPS-Mua-0791Musa acuminata52.552e-97 295
LLPS-Tru-0293Triticum urartu52.534e-88 271
LLPS-Orr-0292Oryza rufipogon52.531e-95 291
LLPS-Ors-0822Oryza sativa52.531e-95 291
LLPS-Orgl-1592Oryza glumaepatula52.532e-95 290
LLPS-Orni-0894Oryza nivara52.531e-95 291
LLPS-Ori-1961Oryza indica52.531e-95 291
LLPS-Art-2829Arabidopsis thaliana52.428e-96 291
LLPS-Sob-1949Sorghum bicolor52.298e-96 291
LLPS-Brd-0727Brachypodium distachyon52.263e-91 279
LLPS-Orb-0967Oryza barthii52.174e-85 262
LLPS-Org-1699Oryza glaberrima52.145e-96 292
LLPS-Orp-1532Oryza punctata52.144e-94 287
LLPS-Tra-1001Triticum aestivum51.753e-93 285
LLPS-Hov-0439Hordeum vulgare51.753e-93 285
LLPS-Zem-0132Zea mays51.535e-93 284
LLPS-Sei-0916Setaria italica51.491e-89 278
LLPS-Arl-2512Arabidopsis lyrata51.091e-93 285
LLPS-Orbr-0650Oryza brachyantha50.991e-92 283
LLPS-Scc-0203Schizosaccharomyces cryophilus50.537e-98 298
LLPS-Asn-0509Aspergillus nidulans49.832e-96 299
LLPS-Ast-0055Aspergillus terreus48.17e-94 293
LLPS-Scj-0535Schizosaccharomyces japonicus47.895e-85 265
LLPS-Nef-0585Neosartorya fischeri47.755e-92 288
LLPS-Asf-0566Aspergillus flavus47.752e-93 292
LLPS-Aso-0143Aspergillus oryzae47.752e-93 292
LLPS-Asc-1146Aspergillus clavatus47.751e-92 290
LLPS-Cae-0089Caenorhabditis elegans47.712e-83 260
LLPS-Beb-0693Beauveria bassiana47.671e-87 276
LLPS-Asfu-0154Aspergillus fumigatus47.42e-91 287
LLPS-Cogr-0619Colletotrichum graminicola47.232e-89 282
LLPS-Fus-0304Fusarium solani47.186e-85 270
LLPS-Fuo-1451Fusarium oxysporum47.01e-85 271
LLPS-Fuv-0658Fusarium verticillioides46.672e-85 271
LLPS-Coo-0036Colletotrichum orbiculare46.468e-83 265
LLPS-Trv-0033Trichoderma virens46.187e-85 270
LLPS-Trr-0965Trichoderma reesei46.151e-84 269
LLPS-Ved-1026Verticillium dahliae45.873e-83 266
LLPS-Nec-0884Neurospora crassa45.031e-80 261
LLPS-Pyt-0749Pyrenophora teres44.771e-84 269
LLPS-Lem-0095Leptosphaeria maculans44.263e-79 264
LLPS-Dos-0423Dothistroma septosporum41.972e-76 248
LLPS-Zyt-0893Zymoseptoria tritici41.51e-76 244