• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-4073
EIF2AK1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Uncharacterized protein
Gene Name: EIF2AK1
Ensembl Gene: ENSAMEG00000009072.1
Ensembl Protein: ENSAMEP00000009570.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: Regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000009984.1ENSAMEP00000009570.1
UniProtG1LR86, G1LR86_AILME
GeneBankACTA01042359, ACTA01034360

▼ SEQUENCE

Protein Sequence (FASTA)
1     WVGWLAGCWA  ATRARRVMLG  GSSGAPAIEF  PADGSDPTYD  ESDVPAELQV  LKGPLQQPTF  60
61    PFAVANQLLL  VSLLEHLSHV  HEPNPLRSRQ  VFKLLCQTFI  KMGLLSSFTC  SDEFSSLRLH  120
121   HNRAITHLMS  SAKERVRQDP  CEDNSHIQKI  RSREVAFEAQ  TSRYLNEFEE  LAILGKGGYG  180
181   RVYKVRNKLD  GQYYAIKKIL  INGATKTDCM  KVLREVKVLA  GLQHPNIVGY  HTAWIEHVHV  240
241   AQTQADSFSV  QLPSLEVLSD  EEEEEENDRN  QYAQNDESNS  SSIIFAEFSS  EKEKSSGEAG  300
301   TDSQNNRLVN  YGTSLITGDS  REFESSSLLQ  GNDLADLPSG  SIVEHQLPLR  HHSDSEENFT  360
361   STGESSENLS  LLGQTEVQFR  LMLHIQMQLC  ELSLWDWIVE  RNRRGREYVD  EAACPYVMAS  420
421   VATKIFQELV  EGVFYIHNMG  IVHRDLKPRN  IFLHGSDQQV  KIGDFGLACT  DIIQKSTDWI  480
481   DNDGKRMPTH  TSRVGTCLYA  SPEQLEGSEY  DAKSDMYSLG  VILLELFQPF  GTEMERVHIL  540
541   TSLRSGQIPE  SLSKRCPVQA  KYIQHLTARN  ASQRPSAVQL  LQSELFQNSG  NVNLILQMKI  600
601   LEQEKEIEEL  RKQLSLLSKD  KGAKGDMRDG  GVPV  634
Nucleotide CDS Sequence (FASTA)
1     TGGGTTGGCT  GGCTGGCGGG  CTGCTGGGCT  GCGACCCGCG  CGCGGCGGGT  CATGCTGGGA  60
61    GGCAGCTCCG  GGGCGCCCGC  CATCGAGTTC  CCGGCGGACG  GCTCGGACCC  CACGTATGAT  120
121   GAATCCGATG  TCCCAGCAGA  ACTCCAGGTA  TTAAAAGGAC  CCCTACAGCA  GCCGACTTTC  180
181   CCTTTTGCAG  TTGCAAACCA  ACTCTTGCTT  GTCTCTTTGC  TGGAGCACTT  GAGCCATGTG  240
241   CACGAACCAA  ACCCTCTCCG  TTCAAGACAG  GTGTTTAAAT  TGCTCTGCCA  GACCTTTATC  300
301   AAAATGGGGC  TGCTGTCTTC  TTTCACCTGT  AGTGATGAGT  TTAGCTCGTT  GAGACTACAC  360
361   CACAACAGAG  CTATTACTCA  TTTAATGAGC  TCTGCTAAAG  AGAGAGTTCG  TCAGGATCCT  420
421   TGTGAGGATA  ATTCTCATAT  CCAGAAGATC  AGATCAAGGG  AAGTAGCCTT  TGAAGCACAG  480
481   ACTTCACGGT  ACCTAAATGA  ATTTGAAGAG  CTTGCCATCT  TAGGAAAAGG  CGGATACGGA  540
541   AGAGTGTACA  AGGTCAGGAA  TAAATTAGAT  GGTCAGTATT  ATGCAATTAA  AAAAATCCTG  600
601   ATTAATGGTG  CAACTAAAAC  AGATTGTATG  AAGGTCCTGC  GGGAGGTGAA  GGTGCTGGCA  660
661   GGCCTTCAGC  ACCCTAATAT  CGTAGGCTAT  CACACTGCTT  GGATCGAACA  CGTTCACGTG  720
721   GCGCAAACAC  AAGCAGATAG  TTTTTCTGTT  CAGCTGCCAT  CTCTGGAAGT  GCTCTCCGAC  780
781   GAGGAGGAGG  AGGAGGAGAA  CGACCGAAAT  CAGTATGCTC  AAAATGATGA  AAGTAACAGC  840
841   TCATCCATTA  TCTTCGCCGA  GTTCTCCTCA  GAAAAAGAAA  AGTCCTCAGG  AGAAGCTGGC  900
901   ACTGACAGTC  AGAATAACAG  ATTGGTGAAC  TATGGCACCA  GTTTAATCAC  AGGAGATTCC  960
961   AGGGAATTTG  AATCATCCAG  TTTGCTCCAA  GGAAATGATT  TGGCTGATTT  GCCTTCCGGA  1020
1021  TCGATTGTTG  AACATCAGCT  GCCGCTTAGG  CATCATTCTG  ACTCGGAAGA  GAATTTCACA  1080
1081  TCCACTGGGG  AGTCTTCTGA  AAACTTAAGT  TTGTTGGGGC  AGACAGAGGT  GCAGTTCCGC  1140
1141  CTGATGTTGC  ACATCCAGAT  GCAGCTGTGC  GAGCTCTCGC  TGTGGGACTG  GATAGTCGAG  1200
1201  AGAAACCGGC  GGGGCCGGGA  GTACGTGGAC  GAAGCGGCAT  GTCCTTATGT  CATGGCCAGT  1260
1261  GTCGCAACAA  AAATTTTTCA  AGAATTGGTG  GAAGGTGTAT  TTTACATCCA  TAACATGGGA  1320
1321  ATTGTACATA  GAGACCTGAA  GCCCAGAAAT  ATTTTTCTTC  ATGGCTCTGA  TCAGCAAGTA  1380
1381  AAAATAGGAG  ACTTTGGTCT  GGCCTGCACA  GACATCATAC  AGAAGAGCAC  AGACTGGATC  1440
1441  GATAACGATG  GGAAGAGGAT  GCCCACACAC  ACTTCCAGAG  TGGGTACTTG  CCTGTACGCA  1500
1501  TCACCGGAGC  AGTTGGAAGG  ATCCGAGTAC  GATGCCAAGT  CAGACATGTA  CAGCTTGGGT  1560
1561  GTGATCCTGC  TAGAGCTCTT  TCAGCCATTT  GGAACAGAAA  TGGAGCGAGT  ACACATTTTA  1620
1621  ACAAGTTTAA  GAAGCGGTCA  GATACCTGAA  TCCCTCAGTA  AGAGGTGTCC  CGTGCAAGCC  1680
1681  AAGTATATCC  AGCACTTAAC  TGCAAGGAAC  GCATCTCAGA  GACCGTCTGC  TGTTCAGCTG  1740
1741  CTGCAAAGCG  AACTTTTCCA  AAATTCTGGA  AATGTTAATC  TCATCCTACA  GATGAAAATA  1800
1801  CTGGAGCAAG  AAAAAGAAAT  CGAAGAACTA  AGGAAGCAGC  TGAGTCTCCT  TTCTAAGGAC  1860
1861  AAAGGGGCCA  AGGGTGACAT  GAGAGATGGG  GGTGTGCCTG  TC  1902

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-0070Ursus maritimus90.40.01011
LLPS-Mup-1322Mustela putorius furo88.720.0 882
LLPS-Caf-3448Canis familiaris86.590.01004
LLPS-Fec-2745Felis catus85.990.0 996
LLPS-Eqc-4449Equus caballus83.960.0 958
LLPS-Pap-2373Pan paniscus82.70.0 924
LLPS-Pat-3995Pan troglodytes82.70.0 923
LLPS-Gog-3411Gorilla gorilla82.370.0 919
LLPS-Hos-0062Homo sapiens82.210.0 920
LLPS-Cas-2643Carlito syrichta81.520.0 947
LLPS-Chs-2027Chlorocebus sabaeus81.520.0 936
LLPS-Otg-3290Otolemur garnettii81.420.0 940
LLPS-Maf-3342Macaca fascicularis81.040.0 928
LLPS-Cea-0186Cercocebus atys80.990.0 909
LLPS-Mal-2192Mandrillus leucophaeus80.880.0 927
LLPS-Caj-4391Callithrix jacchus80.790.0 932
LLPS-Ova-2352Ovis aries80.410.0 923
LLPS-Sus-0713Sus scrofa80.190.0 793
LLPS-Fud-1255Fukomys damarensis80.170.0 851
LLPS-Mam-1075Macaca mulatta80.150.0 832
LLPS-Mum-1591Mus musculus80.10.0 858
LLPS-Myl-0821Myotis lucifugus79.90.0 898
LLPS-Cap-2531Cavia porcellus79.490.0 829
LLPS-Nol-1240Nomascus leucogenys79.410.0 871
LLPS-Dio-0684Dipodomys ordii78.90.0 844
LLPS-Loa-0425Loxodonta africana78.690.0 887
LLPS-Aon-2726Aotus nancymaae78.650.0 854
LLPS-Paa-3838Papio anubis78.440.0 887
LLPS-Orc-1265Oryctolagus cuniculus78.320.0 860
LLPS-Ict-3342Ictidomys tridecemlineatus78.060.0 906
LLPS-Mea-3819Mesocricetus auratus77.990.0 887
LLPS-Bot-0311Bos taurus77.460.0 912
LLPS-Ran-0561Rattus norvegicus77.050.0 849
LLPS-Man-1574Macaca nemestrina76.010.0 848
LLPS-Poa-3296Pongo abelii74.630.0 815
LLPS-Rhb-0532Rhinopithecus bieti69.90.0 788
LLPS-Mod-1337Monodelphis domestica68.770.0 749
LLPS-Sah-2061Sarcophilus harrisii67.890.0 740
LLPS-Gaga-2511Gallus gallus60.876e-71 247
LLPS-Ora-0531Ornithorhynchus anatinus60.612e-152 456
LLPS-Fia-3152Ficedula albicollis60.346e-89 296
LLPS-Anp-1397Anas platyrhynchos59.744e-1893.2
LLPS-Pes-0614Pelodiscus sinensis57.144e-1687.0
LLPS-Scm-1608Scophthalmus maximus57.081e-68 241
LLPS-Scf-1195Scleropages formosus57.023e-71 249
LLPS-Ten-1005Tetraodon nigroviridis56.964e-50 188
LLPS-Xet-3045Xenopus tropicalis56.793e-1790.5
LLPS-Orn-1469Oreochromis niloticus56.761e-66 236
LLPS-Asm-2689Astyanax mexicanus56.681e-66 236
LLPS-Orl-0683Oryzias latipes56.363e-66 235
LLPS-Gaa-1613Gasterosteus aculeatus55.923e-64 229
LLPS-Tar-2971Takifugu rubripes55.71e-73 255
LLPS-Pof-3632Poecilia formosa55.363e-66 235
LLPS-Xim-0615Xiphophorus maculatus55.361e-67 239
LLPS-Leo-0932Lepisosteus oculatus54.749e-69 242
LLPS-Zem-1828Zea mays54.676e-1686.3
LLPS-Sob-1388Sorghum bicolor54.675e-1686.7
LLPS-Tut-2332Tursiops truncatus54.557e-1582.8
LLPS-Anc-2336Anolis carolinensis53.751e-1585.1
LLPS-Orr-1982Oryza rufipogon53.338e-1685.9
LLPS-Org-1439Oryza glaberrima53.338e-1685.9
LLPS-Orbr-1677Oryza brachyantha53.338e-1685.9
LLPS-Orgl-1929Oryza glumaepatula53.339e-1685.5
LLPS-Lep-1221Leersia perrieri53.339e-1685.5
LLPS-Tra-1613Triticum aestivum53.336e-1686.3
LLPS-Sei-0479Setaria italica53.337e-1685.9
LLPS-Hov-2025Hordeum vulgare53.335e-1686.3
LLPS-Ori-2360Oryza indica53.338e-1685.9
LLPS-Orb-1777Oryza barthii53.339e-1685.5
LLPS-Tag-3097Taeniopygia guttata52.631e-1378.6
LLPS-Php-2252Physcomitrella patens52.633e-1687.4
LLPS-Brd-1099Brachypodium distachyon52.333e-1790.5
LLPS-Orni-2140Oryza nivara51.792e-0861.6
LLPS-Icp-1380Ictalurus punctatus51.545e-49 186
LLPS-Meg-2529Meleagris gallopavo51.461e-165 494
LLPS-Coc-2100Corchorus capsularis51.329e-1582.4
LLPS-Dar-1504Danio rerio51.325e-1376.6
LLPS-Pot-1473Populus trichocarpa51.321e-1482.0
LLPS-Sem-1202Selaginella moellendorffii51.282e-1584.3
LLPS-Abg-1030Absidia glauca50.04e-1583.6
LLPS-Cus-2185Cucumis sativus50.07e-1581.6
LLPS-Gor-2324Gossypium raimondii49.333e-1377.4
LLPS-Mae-0895Manihot esculenta49.332e-1378.6
LLPS-Crn-1481Cryptococcus neoformans49.336e-1376.6
LLPS-Glm-1554Glycine max48.842e-1481.3
LLPS-Cogr-1397Colletotrichum graminicola48.726e-1583.2
LLPS-Prp-0447Prunus persica48.681e-1379.0
LLPS-Bro-2052Brassica oleracea48.683e-1480.5
LLPS-Brr-1444Brassica rapa48.684e-1480.1
LLPS-Arl-1309Arabidopsis lyrata48.684e-1480.5
LLPS-Hea-0893Helianthus annuus48.683e-1480.9
LLPS-Scj-0288Schizosaccharomyces japonicus48.654e-1584.0
LLPS-Met-2447Medicago truncatula48.281e-1481.6
LLPS-Cis-1828Ciona savignyi47.836e-1582.8
LLPS-Phv-1041Phaseolus vulgaris47.738e-1582.8
LLPS-Via-2366Vigna angularis47.195e-1583.2
LLPS-Scp-1503Schizosaccharomyces pombe45.883e-1790.1
LLPS-Cog-1497Colletotrichum gloeosporioides44.876e-1479.7
LLPS-Sol-1893Solanum lycopersicum43.553e-0757.8
LLPS-Art-3058Arabidopsis thaliana41.842e-1480.9
LLPS-Lac-3474Latimeria chalumnae41.752e-1274.7
LLPS-Scc-1566Schizosaccharomyces cryophilus41.075e-1893.2
LLPS-Tru-0475Triticum urartu40.234e-26 118
LLPS-Nia-0634Nicotiana attenuata39.772e-26 119
LLPS-Brn-1576Brassica napus37.862e-1068.6
LLPS-Thc-2081Theobroma cacao37.681e-27 123
LLPS-Orp-0205Oryza punctata35.421e-25 116
LLPS-Sac-1083Saccharomyces cerevisiae33.035e-44 175
LLPS-Mua-0677Musa acuminata32.837e-29 123
LLPS-Kop-0918Komagataella pastoris32.192e-38 157
LLPS-Ast-0916Aspergillus terreus31.354e-37 153
LLPS-Cii-1289Ciona intestinalis31.012e-66 233
LLPS-Asg-1504Ashbya gossypii30.94e-43 172
LLPS-Asni-0342Aspergillus niger28.541e-33 141
LLPS-Asn-1377Aspergillus nidulans27.541e-30 132