• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-2952
FLI1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Fli-1 proto-oncogene, ETS transcription factor
Gene Name: FLI1
Ensembl Gene: ENSAMEG00000002559.1
Ensembl Protein: ENSAMEP00000002699.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000002814.1ENSAMEP00000002699.1
UniProtG1L733, G1L733_AILME
GeneBankACTA01184203, ACTA01192201

▼ SEQUENCE

Protein Sequence (FASTA)
1     LTLGFRSPSL  TLQEALSVVS  DDQSLFDSAY  GAAAHLPKAD  MTASGSPDYG  QPHKINPLPP  60
61    QQEWINQPVR  VNVKREYDHM  NGSRESPVDC  SVSKCSKLVG  GSESNAMNYN  SYMDEKNGPP  120
121   PPNMTTNERR  VIVPADPTLW  TQEHVRQWLE  WAIKEYGLME  IDTSFFQNMD  GKELCKMNKE  180
181   DFLRATSLYN  TEVLLSHLSY  LRESSQPHAQ  TDTTDKAIIL  LSPNINHVHI  TGGRTSICPP  240
241   TDPCPKLFMP  VATDVDPSYD  SVRRGGWGSN  MNSGLNKSKS  PALSSLCDTA  ENQRSSLDPY  300
301   QILGPTSSRL  ANPGSGQIQL  WQFLLELLSD  SANASCITWE  GTNGEFKMTD  PDEVARRWGE  360
361   RKSKPNMNYD  KLSRALRYYY  DKNIMTKVHG  KRYAYKFDFH  GIAQALQPHP  TESSMYKYPS  420
421   DISYMPSYHA  HQQKVNFVPP  HPTSMPVTSS  SFFGAASQYW  TSPTGGIYPN  PNVPRHPNTH  480
481   VPSHLGSYY  489
Nucleotide CDS Sequence (FASTA)
1     CTGACACTGG  GCTTTCGGTC  TCCTTCTCTG  ACCCTCCAGG  AGGCTCTGTC  GGTGGTGAGC  60
61    GACGACCAGT  CCCTCTTCGA  CTCTGCCTAC  GGAGCGGCGG  CCCATCTCCC  CAAGGCCGAC  120
121   ATGACCGCCT  CAGGGAGCCC  TGACTATGGC  CAGCCCCACA  AAATCAACCC  CCTCCCACCG  180
181   CAGCAGGAGT  GGATTAATCA  GCCGGTGAGG  GTCAATGTCA  AGCGGGAGTA  TGACCACATG  240
241   AATGGATCCA  GGGAGTCTCC  GGTGGACTGC  AGTGTTAGCA  AATGCAGCAA  GCTAGTTGGT  300
301   GGAAGCGAGT  CCAACGCCAT  GAACTACAAC  AGCTACATGG  ACGAGAAGAA  CGGCCCCCCT  360
361   CCTCCCAACA  TGACCACCAA  CGAGAGAAGG  GTCATCGTCC  CCGCAGACCC  CACGCTGTGG  420
421   ACTCAGGAGC  ACGTGCGGCA  GTGGCTGGAG  TGGGCGATAA  AAGAGTATGG  CTTGATGGAG  480
481   ATCGACACGT  CCTTCTTCCA  AAACATGGAT  GGCAAGGAAC  TGTGTAAAAT  GAACAAGGAG  540
541   GACTTCCTCC  GAGCCACTTC  CCTCTACAAC  ACCGAAGTGC  TGCTGTCACA  TCTCAGTTAT  600
601   CTCAGGGAAA  GCTCACAGCC  TCATGCTCAG  ACAGATACTA  CAGATAAGGC  CATAATTTTG  660
661   TTGTCTCCCA  ACATAAATCA  TGTGCACATT  ACTGGAGGTC  GAACCAGCAT  TTGCCCCCCC  720
721   ACTGACCCCT  GCCCCAAACT  TTTCATGCCA  GTTGCTACAG  ACGTAGACCC  TTCTTATGAC  780
781   TCAGTCAGGA  GAGGAGGATG  GGGCAGTAAC  ATGAATTCTG  GCCTCAACAA  AAGTAAAAGC  840
841   CCAGCTCTGT  CGTCTCTGTG  TGACACAGCA  GAAAACCAGA  GATCTTCCTT  AGATCCATAT  900
901   CAGATCCTGG  GCCCGACCAG  CAGTCGCCTC  GCCAACCCTG  GCAGTGGGCA  GATCCAATTG  960
961   TGGCAGTTCC  TCCTCGAGCT  TCTCTCCGAC  AGCGCGAATG  CCAGCTGTAT  CACCTGGGAG  1020
1021  GGGACCAACG  GGGAGTTCAA  AATGACGGAC  CCCGATGAGG  TGGCCCGGCG  CTGGGGGGAG  1080
1081  CGGAAAAGCA  AGCCCAACAT  GAATTACGAC  AAGCTGAGCC  GGGCCCTCAG  ATACTACTAT  1140
1141  GATAAAAACA  TTATGACCAA  AGTGCATGGC  AAGAGGTATG  CCTACAAATT  TGACTTCCAC  1200
1201  GGCATCGCTC  AGGCCCTGCA  GCCACATCCC  ACTGAGTCGT  CCATGTACAA  GTACCCTTCT  1260
1261  GACATCTCCT  ACATGCCCTC  CTACCACGCC  CATCAACAGA  AGGTGAACTT  TGTCCCTCCC  1320
1321  CACCCGACCT  CCATGCCCGT  CACCTCCTCT  AGCTTCTTTG  GAGCAGCGTC  GCAATACTGG  1380
1381  ACCTCGCCCA  CGGGTGGGAT  TTACCCCAAC  CCCAATGTCC  CCCGCCATCC  CAACACCCAC  1440
1441  GTGCCCTCCC  ACTTAGGCAG  CTACTACTAG  1470

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-1055Fukomys damarensis88.01e-39 147
LLPS-Mal-4743Mandrillus leucophaeus87.648e-51 176
LLPS-Pap-0423Pan paniscus86.69e-55 187
LLPS-Mup-3463Mustela putorius furo86.220.0 838
LLPS-Ict-2983Ictidomys tridecemlineatus86.040.0 832
LLPS-Caf-3372Canis familiaris85.80.0 827
LLPS-Cap-2840Cavia porcellus85.710.0 827
LLPS-Caj-2965Callithrix jacchus85.560.0 829
LLPS-Cea-4121Cercocebus atys85.530.0 827
LLPS-Fec-3563Felis catus85.420.0 841
LLPS-Rhb-4636Rhinopithecus bieti85.390.0 830
LLPS-Chs-0346Chlorocebus sabaeus85.390.0 830
LLPS-Man-4116Macaca nemestrina85.360.0 830
LLPS-Maf-3464Macaca fascicularis85.320.0 826
LLPS-Paa-3575Papio anubis85.320.0 824
LLPS-Pat-2817Pan troglodytes85.180.0 828
LLPS-Hos-1376Homo sapiens85.180.0 828
LLPS-Nol-2820Nomascus leucogenys85.180.0 827
LLPS-Gog-4802Gorilla gorilla85.180.0 828
LLPS-Loa-2064Loxodonta africana85.150.0 827
LLPS-Mam-1069Macaca mulatta84.970.0 827
LLPS-Cas-2240Carlito syrichta84.760.0 825
LLPS-Eqc-4762Equus caballus84.760.0 827
LLPS-Dio-2119Dipodomys ordii84.760.0 823
LLPS-Poa-3215Pongo abelii84.730.0 823
LLPS-Aon-3054Aotus nancymaae84.650.0 826
LLPS-Ran-1147Rattus norvegicus84.440.0 816
LLPS-Sus-4432Sus scrofa84.390.0 834
LLPS-Orc-3382Oryctolagus cuniculus84.340.0 826
LLPS-Bot-4148Bos taurus84.250.0 824
LLPS-Mum-4502Mus musculus83.920.0 816
LLPS-Ova-0446Ovis aries83.750.0 742
LLPS-Otg-2915Otolemur garnettii83.680.0 824
LLPS-Cae-1743Caenorhabditis elegans82.766e-60 207
LLPS-Anp-2034Anas platyrhynchos82.010.0 790
LLPS-Sah-3742Sarcophilus harrisii81.910.0 745
LLPS-Pes-3439Pelodiscus sinensis81.827e-60 200
LLPS-Mod-2970Monodelphis domestica81.740.0 746
LLPS-Meg-1359Meleagris gallopavo81.460.0 785
LLPS-Mea-1385Mesocricetus auratus81.190.0 659
LLPS-Xet-0647Xenopus tropicalis80.79e-60 202
LLPS-Urm-3950Ursus maritimus80.250.0 751
LLPS-Fia-2737Ficedula albicollis80.040.0 769
LLPS-Tut-0314Tursiops truncatus79.410.0 716
LLPS-Anc-0065Anolis carolinensis78.880.0 753
LLPS-Myl-2468Myotis lucifugus78.60.0 750
LLPS-Gaa-1850Gasterosteus aculeatus77.958e-63 210
LLPS-Drm-0541Drosophila melanogaster77.489e-52 188
LLPS-Lac-1825Latimeria chalumnae76.60.0 747
LLPS-Scm-2372Scophthalmus maximus76.387e-62 207
LLPS-Orl-1795Oryzias latipes76.383e-61 207
LLPS-Leo-1204Lepisosteus oculatus75.940.0 717
LLPS-Tag-0658Taeniopygia guttata75.720.0 727
LLPS-Dar-0573Danio rerio75.596e-61 206
LLPS-Pof-2099Poecilia formosa75.420.0 713
LLPS-Tar-3121Takifugu rubripes75.420.0 711
LLPS-Xim-2559Xiphophorus maculatus75.420.0 714
LLPS-Scf-3862Scleropages formosus75.00.0 709
LLPS-Ten-3364Tetraodon nigroviridis74.690.0 711
LLPS-Orn-3170Oreochromis niloticus73.140.0 715
LLPS-Icp-3566Ictalurus punctatus71.730.0 683
LLPS-Gaga-3564Gallus gallus70.242e-32 132
LLPS-Asm-3333Astyanax mexicanus70.248e-33 134
LLPS-Ora-2047Ornithorhynchus anatinus70.243e-32 132
LLPS-Cii-0362Ciona intestinalis34.832e-38 149