• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-2313
DYRK3

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Dual specificity tyrosine phosphorylation regulated kinase 3
Gene Name: DYRK3
Ensembl Gene: ENSAMEG00000017518.1
Ensembl Protein: ENSAMEP00000018506.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000019250.1ENSAMEP00000018506.1
UniProtG1MGM2, G1MGM2_AILME
GeneBankACTA01042214

▼ SEQUENCE

Protein Sequence (FASTA)
1     PARGPGRKDA  EPPGAGLPPQ  QRRLGDGVYD  TFMMIDETKC  PPCSNVLCNP  SEPPLPRRLN  60
61    ITAEQLPRDH  TQRFLNGGEV  KVEQLFQEFG  NRRSDTLQSD  GINDSEKCSP  PDSQGKSSDS  120
121   LNAVKPSSSA  KASKVVPLTP  EQALKQYKHH  LTAYEKLEII  NYPEIYFVGP  NAKKRHGVIG  180
181   GPNNSGYDDA  DGAYIHVPRD  HLAYRYEVLK  IIGKGSFGQV  ARVYDHKLRQ  YVALKMVRNE  240
241   KRFHRQAAEE  IRILEHLKKQ  DKTGSMNVIH  MLESFTFRNH  VCMAFELLSI  DLYELIKKNK  300
301   FQGFSVQLVR  KFAQSILQSL  DALHKNKIIH  CDLKPENILL  KHHGRSATKV  IDFGSSCFEY  360
361   QKLYTYIQSR  FYRAPEIILG  SRYSTPIDIW  SFGCILAELL  TGQPLFPGED  EGDQLACMME  420
421   LLGMPPPKLL  EQSKRAKYFI  NSKGLPRYCS  VTTQADGRVV  LVGGRSRRGK  KRGPPGSKDW  480
481   VTALKGCDDY  LFIEFLKRCL  HWDPSARLTP  AQALRHPWIS  KCVPRPLTIE  KVSGKRVVNP  540
541   TNAFQGLGSK  LPPVVGIANK  LKANLMSETN  GGIPLCSVLP  KLIS  584
Nucleotide CDS Sequence (FASTA)
1     CCGGCGCGCG  GGCCCGGGCG  GAAGGATGCG  GAGCCGCCTG  GAGCCGGACT  CCCGCCCCAG  60
61    CAGCGGAGAT  TGGGGGATGG  TGTCTATGAT  ACCTTCATGA  TGATAGATGA  AACCAAATGT  120
121   CCACCCTGTT  CAAATGTACT  CTGCAATCCT  TCTGAACCGC  CTCTACCCCG  AAGACTAAAT  180
181   ATCACTGCTG  AGCAGTTACC  AAGAGATCAC  ACTCAGCGCT  TTCTGAATGG  AGGTGAGGTG  240
241   AAAGTAGAAC  AGCTGTTTCA  AGAATTTGGC  AACAGAAGAT  CTGATACTCT  TCAGTCAGAT  300
301   GGCATCAACG  ACTCTGAAAA  ATGCTCTCCT  CCCGACTCTC  AGGGTAAAAG  TTCAGATAGC  360
361   TTGAATGCGG  TGAAACCCAG  CAGTTCAGCC  AAAGCTTCCA  AAGTGGTGCC  ACTGACTCCA  420
421   GAGCAAGCAC  TGAAGCAATA  CAAACACCAC  CTCACTGCTT  ACGAGAAGCT  GGAAATCATC  480
481   AATTACCCAG  AAATTTACTT  TGTGGGCCCA  AATGCCAAAA  AAAGACACGG  AGTGATCGGT  540
541   GGTCCCAATA  ACAGCGGGTA  TGATGATGCA  GATGGGGCCT  ATATTCATGT  GCCTCGTGAC  600
601   CATCTGGCTT  ATCGATATGA  GGTGCTGAAA  ATTATTGGCA  AGGGAAGTTT  TGGGCAAGTA  660
661   GCCCGGGTCT  ACGATCATAA  ACTTCGACAG  TATGTGGCCC  TAAAGATGGT  ACGCAATGAA  720
721   AAGCGCTTCC  ATCGTCAAGC  AGCTGAGGAG  ATCCGGATTT  TGGAGCATCT  TAAAAAGCAG  780
781   GACAAGACGG  GTAGCATGAA  TGTCATCCAC  ATGCTGGAAA  GTTTCACATT  CCGGAATCAT  840
841   GTTTGCATGG  CCTTCGAATT  GCTGAGCATA  GACCTTTATG  AGCTAATTAA  AAAAAACAAG  900
901   TTTCAGGGTT  TTAGCGTCCA  GTTAGTTCGC  AAGTTTGCTC  AATCCATCTT  GCAATCCTTG  960
961   GATGCTCTCC  ACAAAAATAA  GATCATTCAC  TGTGACCTGA  AGCCAGAAAA  CATTCTCCTG  1020
1021  AAACACCATG  GGCGCAGTGC  GACCAAGGTC  ATTGACTTTG  GGTCCAGCTG  TTTCGAATAC  1080
1081  CAGAAGCTTT  ACACATATAT  CCAGTCTCGG  TTCTACAGAG  CTCCAGAGAT  CATCTTAGGG  1140
1141  AGCCGCTACA  GCACGCCTAT  AGACATATGG  AGTTTTGGCT  GCATCCTTGC  AGAACTTTTA  1200
1201  ACAGGACAGC  CTCTCTTCCC  GGGAGAGGAT  GAAGGAGACC  AGTTGGCCTG  TATGATGGAG  1260
1261  CTGCTAGGAA  TGCCACCACC  AAAACTTCTG  GAGCAATCCA  AACGTGCCAA  GTACTTCATT  1320
1321  AACTCCAAGG  GCCTACCTCG  CTACTGTTCT  GTGACTACTC  AGGCAGACGG  GAGGGTTGTA  1380
1381  CTTGTGGGGG  GTCGCTCACG  TAGGGGTAAA  AAGCGGGGTC  CCCCAGGCAG  CAAAGACTGG  1440
1441  GTGACAGCAC  TGAAGGGATG  TGATGACTAC  TTGTTTATAG  AGTTTTTGAA  AAGGTGTCTT  1500
1501  CACTGGGACC  CCTCTGCCCG  TTTGACCCCA  GCTCAAGCAC  TGAGACATCC  ATGGATTAGT  1560
1561  AAGTGTGTGC  CCAGACCTCT  CACCATTGAA  AAGGTGTCAG  GAAAACGGGT  GGTAAATCCC  1620
1621  ACAAACGCTT  TCCAGGGACT  GGGTTCCAAG  CTGCCTCCAG  TTGTCGGAAT  AGCCAATAAG  1680
1681  CTTAAAGCTA  ACTTAATGTC  AGAAACCAAT  GGTGGTATAC  CTCTGTGCAG  TGTACTGCCA  1740
1741  AAGCTCATTA  GCTAA  1755

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-2882Ursus maritimus99.820.01052
LLPS-Caf-1974Canis familiaris97.940.01098
LLPS-Fec-4306Felis catus97.430.01093
LLPS-Mup-0847Mustela putorius furo96.40.01093
LLPS-Eqc-2952Equus caballus95.10.0 997
LLPS-Ova-1340Ovis aries95.020.01028
LLPS-Tut-1307Tursiops truncatus94.970.01059
LLPS-Sus-2864Sus scrofa94.760.0 949
LLPS-Chs-3869Chlorocebus sabaeus94.690.01069
LLPS-Pat-3411Pan troglodytes94.690.01070
LLPS-Rhb-4543Rhinopithecus bieti94.690.01070
LLPS-Ict-4274Ictidomys tridecemlineatus94.680.01046
LLPS-Gog-0169Gorilla gorilla94.520.01068
LLPS-Paa-0758Papio anubis94.520.01066
LLPS-Hos-2002Homo sapiens94.520.01068
LLPS-Pap-4155Pan paniscus94.520.01062
LLPS-Bot-4677Bos taurus94.380.01007
LLPS-Cea-0111Cercocebus atys94.350.01068
LLPS-Man-4554Macaca nemestrina94.350.01067
LLPS-Cas-0797Carlito syrichta94.350.01068
LLPS-Maf-4612Macaca fascicularis94.180.01065
LLPS-Loa-3579Loxodonta africana94.170.01036
LLPS-Mal-1291Mandrillus leucophaeus94.010.01063
LLPS-Mam-2622Macaca mulatta93.980.01026
LLPS-Myl-0407Myotis lucifugus93.830.01066
LLPS-Caj-3683Callithrix jacchus92.810.01034
LLPS-Otg-4445Otolemur garnettii92.290.01026
LLPS-Mea-0763Mesocricetus auratus92.280.01040
LLPS-Nol-2474Nomascus leucogenys92.120.01031
LLPS-Cap-1669Cavia porcellus91.420.01041
LLPS-Ran-0675Rattus norvegicus90.390.01013
LLPS-Orc-1936Oryctolagus cuniculus90.220.0 998
LLPS-Mum-3320Mus musculus90.050.01010
LLPS-Aon-1510Aotus nancymaae89.730.01004
LLPS-Dio-3508Dipodomys ordii89.380.0 993
LLPS-Sah-0688Sarcophilus harrisii88.530.01000
LLPS-Mod-0609Monodelphis domestica88.010.0 968
LLPS-Fud-1535Fukomys damarensis87.030.0 946
LLPS-Anc-3148Anolis carolinensis75.730.0 770
LLPS-Cii-0752Ciona intestinalis72.750.0 580
LLPS-Tag-3383Taeniopygia guttata72.350.0 725
LLPS-Meg-0730Meleagris gallopavo71.960.0 787
LLPS-Gaga-3370Gallus gallus71.770.0 798
LLPS-Pes-2378Pelodiscus sinensis71.380.0 770
LLPS-Cis-1522Ciona savignyi70.440.0 561
LLPS-Fia-1556Ficedula albicollis68.90.0 737
LLPS-Leo-0174Lepisosteus oculatus68.210.0 666
LLPS-Lac-3984Latimeria chalumnae68.130.0 738
LLPS-Xet-3604Xenopus tropicalis67.780.0 696
LLPS-Ten-1018Tetraodon nigroviridis67.610.0 599
LLPS-Orl-1145Oryzias latipes67.540.0 593
LLPS-Icp-1692Ictalurus punctatus67.250.0 640
LLPS-Cae-0280Caenorhabditis elegans67.181e-178 533
LLPS-Asm-0173Astyanax mexicanus66.670.0 637
LLPS-Drm-1365Drosophila melanogaster66.586e-170 511
LLPS-Dar-0752Danio rerio66.470.0 627
LLPS-Anp-0109Anas platyrhynchos66.150.0 665
LLPS-Poa-2121Pongo abelii65.760.0 655
LLPS-Scf-2506Scleropages formosus65.70.0 638
LLPS-Ere-0389Erinaceus europaeus65.380.0 654
LLPS-Ora-0824Ornithorhynchus anatinus65.060.0 622
LLPS-Tar-0404Takifugu rubripes64.730.0 593
LLPS-Pof-0864Poecilia formosa63.050.0 611
LLPS-Orn-1519Oreochromis niloticus62.40.0 603
LLPS-Xim-0298Xiphophorus maculatus62.10.0 613
LLPS-Gaa-1777Gasterosteus aculeatus55.890.0 600
LLPS-Scm-1591Scophthalmus maximus55.130.0 572
LLPS-Sem-2166Selaginella moellendorffii52.349e-124 392
LLPS-Spr-0318Sporisorium reilianum52.332e-120 399
LLPS-Usm-1120Ustilago maydis51.825e-117 389
LLPS-Asni-0586Aspergillus niger50.782e-117 386
LLPS-Aso-1071Aspergillus oryzae50.652e-121 376
LLPS-Asf-0556Aspergillus flavus50.653e-117 383
LLPS-Lem-1457Leptosphaeria maculans50.392e-111 370
LLPS-Asc-0491Aspergillus clavatus50.133e-115 379
LLPS-Miv-1213Microbotryum violaceum50.131e-113 380
LLPS-Nef-0145Neosartorya fischeri50.126e-119 389
LLPS-Asfu-1169Aspergillus fumigatus50.122e-119 390
LLPS-Mel-0064Melampsora laricipopulina49.878e-128 391
LLPS-Trv-1476Trichoderma virens49.741e-114 377
LLPS-Ved-1416Verticillium dahliae49.736e-115 374
LLPS-Pyt-1521Pyrenophora teres49.619e-115 379
LLPS-Pytr-0816Pyrenophora triticirepentis49.611e-120 375
LLPS-Phn-0409Phaeosphaeria nodorum49.614e-115 380
LLPS-Cog-0036Colletotrichum gloeosporioides49.493e-117 385
LLPS-Crn-0948Cryptococcus neoformans49.333e-113 375
LLPS-Chr-1349Chlamydomonas reinhardtii49.244e-125 404
LLPS-Beb-0688Beauveria bassiana49.246e-115 379
LLPS-Ast-0965Aspergillus terreus49.177e-118 387
LLPS-Put-0441Puccinia triticina49.11e-120 397
LLPS-Mao-0939Magnaporthe oryzae49.096e-116 382
LLPS-Trr-0672Trichoderma reesei49.087e-120 368
LLPS-Map-0739Magnaporthe poae48.972e-116 383
LLPS-Cogr-0519Colletotrichum graminicola48.858e-116 380
LLPS-Tum-1414Tuber melanosporum48.632e-118 389
LLPS-Abg-1599Absidia glauca48.261e-120 391
LLPS-Asn-0089Aspergillus nidulans48.252e-118 389
LLPS-Coo-0223Colletotrichum orbiculare47.961e-116 383
LLPS-Blg-0482Blumeria graminis47.532e-114 377
LLPS-Gag-1059Gaeumannomyces graminis47.35e-116 382
LLPS-Scj-0077Schizosaccharomyces japonicus46.94e-103 340
LLPS-Dos-0950Dothistroma septosporum46.331e-106 335
LLPS-Scp-0086Schizosaccharomyces pombe45.292e-101 337
LLPS-Zyt-1151Zymoseptoria tritici45.231e-109 342
LLPS-Scc-1067Schizosaccharomyces cryophilus44.922e-96 324
LLPS-Pug-0248Puccinia graminis44.627e-100 339
LLPS-Nec-0524Neurospora crassa43.761e-115 380
LLPS-Scs-0866Sclerotinia sclerotiorum43.543e-113 374
LLPS-Yal-0220Yarrowia lipolytica42.151e-94 320
LLPS-Fus-1035Fusarium solani40.373e-118 387
LLPS-Fuo-1027Fusarium oxysporum40.362e-119 391
LLPS-Osl-0223Ostreococcus lucimarinus36.794e-79 261