• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-2218
MKNK1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: MAP kinase interacting serine/threonine kinase 1
Gene Name: MKNK1
Ensembl Gene: ENSAMEG00000014008.1
Ensembl Protein: ENSAMEP00000014788.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, Spindle apparatusPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000015398.1ENSAMEP00000014788.1
UniProtG1M620, G1M620_AILME
GeneBankACTA01057749

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLNKFTAFLH  FFLPSFKNNS  PSTSSVSKES  LNHLSLLAYP  LPLKSMQNRP  EMGSSEPLPI  60
61    AEGDRRKKKK  RKARATDSLP  GKFEDTYKLT  SELLGEGAYA  KVQGAVSLQN  GKEYAVKIIE  120
121   KQAGHSRSRV  FREVETLYQC  QGNKNILELI  EFFEDDTRFY  LVFEKLQGGS  ILAHIQKQKH  180
181   FNEREASRVV  RDVAAALDFL  HTKGIAHRDL  KPENILCESP  EKVSPVKICD  FDLGSGVKLN  240
241   NSCTPITTPE  LTTPCGSAEY  MAPEVVEVFR  DEATFYDKRC  DLWSLGVVLY  IMLSGYPPFV  300
301   GHCGTDCGWD  RGEVCRVCQN  KLFESIQEGK  YEFPDKDWAH  ISSEAKDLIS  KLLVRDAKQR  360
361   LSAAQVLQHP  WVQGQAPERG  LPTPQVLQRN  SSTMDLTLFA  AEAIALNRQL  SQREEDELAE  420
421   ESESLVEGLC  SVRLSPPCKS  RLARRR  446
Nucleotide CDS Sequence (FASTA)
1     ATGCTTAATA  AATTCACTGC  CTTCCTACAT  TTTTTTCTTC  CTAGTTTCAA  AAACAACTCT  60
61    CCTTCAACAA  GTTCTGTTTC  CAAGGAAAGT  CTTAACCATT  TGTCCCTTCT  GGCGTACCCT  120
121   CTTCCATTGA  AATCCATGCA  GAATAGACCA  GAGATGGGCA  GCAGTGAACC  CCTTCCCATC  180
181   GCAGAGGGTG  ACAGGAGGAA  AAAGAAGAAG  CGGAAGGCCC  GGGCCACTGA  CTCCTTACCA  240
241   GGGAAGTTTG  AAGATACGTA  CAAGCTGACC  TCTGAATTGC  TTGGAGAGGG  AGCCTATGCC  300
301   AAAGTTCAAG  GTGCTGTGAG  CCTGCAGAAT  GGCAAAGAGT  ATGCTGTCAA  AATCATCGAA  360
361   AAACAAGCAG  GGCACAGCCG  GAGTAGGGTG  TTCCGAGAGG  TGGAGACGCT  CTATCAGTGT  420
421   CAGGGAAACA  AGAACATTTT  GGAGCTGATT  GAGTTCTTTG  AAGATGACAC  AAGGTTTTAC  480
481   TTGGTCTTTG  AGAAATTGCA  AGGAGGCTCC  ATCCTGGCCC  ACATCCAGAA  GCAGAAGCAC  540
541   TTCAATGAGC  GAGAAGCCAG  CCGAGTGGTG  CGGGATGTGG  CCGCTGCCCT  TGACTTTCTG  600
601   CACACCAAAG  GCATCGCTCA  TCGTGACCTG  AAGCCGGAAA  ATATATTGTG  TGAGTCTCCA  660
661   GAAAAGGTGT  CTCCAGTGAA  AATCTGTGAC  TTTGACTTGG  GCAGTGGGGT  GAAATTGAAC  720
721   AACTCCTGCA  CCCCCATAAC  CACACCAGAG  CTGACCACTC  CATGTGGCTC  TGCGGAGTAC  780
781   ATGGCCCCAG  AGGTGGTGGA  GGTCTTCAGG  GACGAGGCCA  CATTTTACGA  CAAGCGCTGT  840
841   GACCTGTGGA  GCCTGGGCGT  GGTTCTCTAC  ATCATGCTGA  GCGGCTACCC  GCCCTTCGTA  900
901   GGTCACTGTG  GGACCGACTG  TGGCTGGGAC  CGCGGAGAGG  TCTGCAGGGT  GTGCCAGAAC  960
961   AAGCTGTTCG  AGAGCATCCA  GGAAGGCAAG  TACGAGTTTC  CCGACAAGGA  CTGGGCACAC  1020
1021  ATCTCCAGCG  AGGCCAAAGA  CCTCATCTCC  AAGCTCCTGG  TTCGCGATGC  AAAGCAGAGA  1080
1081  CTGAGTGCTG  CCCAAGTTCT  GCAGCACCCG  TGGGTGCAGG  GGCAAGCTCC  AGAAAGGGGA  1140
1141  CTCCCCACGC  CGCAAGTCCT  CCAGAGAAAT  AGCAGCACGA  TGGACCTGAC  ACTCTTCGCG  1200
1201  GCTGAGGCCA  TCGCCCTTAA  CCGCCAGCTT  TCTCAGCGCG  AGGAAGACGA  GCTGGCAGAG  1260
1261  GAGTCCGAGT  CCCTGGTCGA  GGGCCTCTGC  TCTGTGAGGC  TTTCCCCCCC  CTGCAAGTCA  1320
1321  CGCCTGGCTC  GCCGGAGG  1338

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-2507Ursus maritimus99.750.0 747
LLPS-Mup-3306Mustela putorius furo99.490.0 746
LLPS-Caf-2493Canis familiaris98.390.0 829
LLPS-Eqc-0720Equus caballus97.570.0 672
LLPS-Man-0450Macaca nemestrina95.960.0 736
LLPS-Chs-0400Chlorocebus sabaeus95.760.0 747
LLPS-Poa-0824Pongo abelii95.510.0 745
LLPS-Otg-0709Otolemur garnettii95.440.0 731
LLPS-Cea-2606Cercocebus atys94.990.0 811
LLPS-Sus-2260Sus scrofa94.940.0 727
LLPS-Dio-2568Dipodomys ordii94.680.0 720
LLPS-Mea-1849Mesocricetus auratus94.180.0 724
LLPS-Fud-2778Fukomys damarensis94.180.0 723
LLPS-Myl-1681Myotis lucifugus94.010.0 729
LLPS-Ran-2031Rattus norvegicus94.010.0 736
LLPS-Mum-0706Mus musculus93.920.0 723
LLPS-Tut-0544Tursiops truncatus93.750.0 710
LLPS-Orc-0265Oryctolagus cuniculus93.670.0 723
LLPS-Cap-2289Cavia porcellus93.270.0 735
LLPS-Bot-1206Bos taurus92.080.0 728
LLPS-Loa-1058Loxodonta africana91.980.0 721
LLPS-Sah-0087Sarcophilus harrisii91.040.0 636
LLPS-Ova-1632Ovis aries89.90.0 714
LLPS-Cas-0341Carlito syrichta89.050.0 703
LLPS-Fec-0399Felis catus88.940.0 724
LLPS-Mod-1121Monodelphis domestica87.590.0 684
LLPS-Nol-2344Nomascus leucogenys87.360.0 722
LLPS-Aon-0038Aotus nancymaae86.890.0 676
LLPS-Mam-0172Macaca mulatta86.840.0 712
LLPS-Maf-1958Macaca fascicularis86.840.0 712
LLPS-Paa-3343Papio anubis86.730.0 717
LLPS-Pap-0611Pan paniscus86.50.0 721
LLPS-Pat-2300Pan troglodytes86.50.0 715
LLPS-Hos-1875Homo sapiens86.50.0 714
LLPS-Rhb-0563Rhinopithecus bieti86.50.0 720
LLPS-Mal-0837Mandrillus leucophaeus86.50.0 722
LLPS-Gog-1451Gorilla gorilla86.50.0 721
LLPS-Gaga-1536Gallus gallus86.360.0 684
LLPS-Fia-1338Ficedula albicollis85.860.0 671
LLPS-Tag-2554Taeniopygia guttata85.610.0 687
LLPS-Caj-0229Callithrix jacchus85.170.0 674
LLPS-Anc-1259Anolis carolinensis83.910.0 682
LLPS-Meg-0930Meleagris gallopavo82.910.0 650
LLPS-Scm-1878Scophthalmus maximus82.480.0 563
LLPS-Lac-0534Latimeria chalumnae80.940.0 603
LLPS-Pes-1149Pelodiscus sinensis79.460.0 700
LLPS-Leo-2443Lepisosteus oculatus79.440.0 634
LLPS-Orn-2419Oreochromis niloticus79.250.0 612
LLPS-Anp-1869Anas platyrhynchos78.260.0 661
LLPS-Tar-0415Takifugu rubripes78.170.0 607
LLPS-Xet-1310Xenopus tropicalis78.030.0 618
LLPS-Orl-0601Oryzias latipes77.570.0 599
LLPS-Gaa-0228Gasterosteus aculeatus77.30.0 592
LLPS-Asm-2904Astyanax mexicanus76.960.0 612
LLPS-Ten-0925Tetraodon nigroviridis76.340.0 593
LLPS-Dar-2378Danio rerio75.120.0 608
LLPS-Pof-0552Poecilia formosa74.220.0 616
LLPS-Icp-1382Ictalurus punctatus74.150.0 607
LLPS-Xim-0393Xiphophorus maculatus73.730.0 614
LLPS-Ict-0185Ictidomys tridecemlineatus68.530.0 573
LLPS-Scf-1730Scleropages formosus65.020.0 548
LLPS-Cis-1330Ciona savignyi59.354e-150 439
LLPS-Cii-0681Ciona intestinalis58.542e-147 435
LLPS-Drm-0227Drosophila melanogaster57.691e-131 414
LLPS-Cae-0946Caenorhabditis elegans49.552e-108 343
LLPS-Chr-1584Chlamydomonas reinhardtii35.749e-51 182
LLPS-Gas-0441Galdieria sulphuraria35.479e-50 180