LLPS-Aim-2193
PLCB1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Phosphoinositide phospholipase C |
| Gene Name: | PLCB1, PANDA_010099 |
| Ensembl Gene: | ENSAMEG00000002350.1 |
| Ensembl Protein: | ENSAMEP00000002558.1 |
| Organism: | Ailuropoda melanoleuca |
| Taxa ID: | 9646 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Postsynaptic density | Predicted from orthologs | (View) |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSAMET00000002669.1 | ENSAMEP00000002558.1 |
| UniProt | D2HGF5, D2HGF5_AILME | |
| GeneBank | GL192809, ACTA01099297, ACTA01131297, ACTA01115297, ACTA01123297, ACTA01107297 | , EFB16864.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 QDPKLRELLD VGNIGRLEHR MITVVYGPDL VNISHLNLVA FQEEVAKEWT NEVFSLATNL 60 61 LAQNMSRDAF LEKAYTKLKL QVTPEGRIPL KNIYRLFSAD RKRVETALEA CSLPSSRNDS 120 121 IPQEDFTPEV YRVFLNNLCP RPEIDNIFSE FGAKSKPYLT VDQMMDFINL KQRDPRLNEI 180 181 LYPPLKQEQV QVLIEKYEPN NSLAKKGQIS VDGFMRYLSG EENGVVSPEK LDLNEDMSQP 240 241 LSHYFINSSH NTYLTAGQLA GNSSVEMYRQ VLLSGCRCVE LDCWKGRTAE EEPVITHGFT 300 301 MTTEISFKEV IEAIAECAFK TSPFPILLSF ENHVDSPKQQ AKMAEYCRLI FGDALLMEPL 360 361 EKYPLESGVP LPSPMDLMYK ILVKNKKKSH KSSEGSGKKK LSEQASNTYS DSSSVFEPSS 420 421 PGAGEADTES DDDDDDDDCK KSSMDEGTAG SEAMATEEMS NLVNYIQPVK FESFEISKKR 480 481 NRSFEMSSFV ETKGLEQLTK SPVEFVEYNK MQLSRIYPKG TRVDSSNYMP QLFWNAGCQM 540 541 VALNFQTVDL AMQINMGMYE YNGKSGYRLK PEFMRRPDKH FDPFTEGIVD GIVANTLSVK 600 601 IISGQFLSDK KVGTYVEVDM FGLPVDTRRK AFKTKTSQGN AVNPVWEEEP IVFKKVVLPS 660 661 LACLRIAVYE EGGKFIGHRI LPVQAIRPGY HYICLRNERN QPLTLPAVFV YIEVKDYVPD 720 721 TYADVIEALS NPIRYVNLME QRAKQLAALT LEDEEEVKKE ADPGETPSEA PSEARTTPAE 780 781 NGVNHTTSLA PKPPSQALHS QPAPGSVKAP AKTEDLIQSV LTEVEAQTIE ELKQQKSFVK 840 841 LQKKHYKEMK DLVKRHHRKT TDLIKEHTTK YNEIQNDYLR RRAALEKTAK KDSKKKSDPS 900 901 SPDHGSSTIE QDLAALDAEM TQKLIDLKDK QQQQLLNLRQ EQYYSEKYQK REHIKLLIQK 960 961 LTDVAEECQN NQLKKLKEIC EKEKKELKKK MDKKRQEKIT EAKSKDKSQM EEEKTEMIRS 1020 1021 YIQEVVQYIK RLEEAQSKRQ EKLVEKHKEI RQQILDEKPK LQTDLEQEYQ DKFKRLPLEI 1080 1081 LEFVQEAMKG KINEDSNHSS APPSLASEPG KMNHKPPSSE ELEGDNPGKE FDTPL 1135 |
| Nucleotide CDS Sequence (FASTA) |
1 CAGGACCCCA AATTACGTGA ACTTTTGGAT GTGGGGAACA TCGGGCGCCT GGAGCATCGC 60 61 ATGATAACAG TGGTGTATGG GCCTGACTTG GTTAACATCT CCCACTTGAA TCTCGTGGCT 120 121 TTCCAAGAAG AAGTGGCCAA GGAATGGACA AATGAGGTTT TCAGTTTGGC AACAAACCTG 180 181 CTGGCCCAAA ACATGTCAAG AGACGCATTT CTGGAAAAAG CCTATACTAA GCTTAAGCTG 240 241 CAAGTCACTC CAGAAGGGCG CATTCCTCTC AAAAACATAT ACCGCTTGTT CTCAGCAGAC 300 301 CGGAAGCGAG TTGAAACTGC TTTAGAGGCT TGTAGTCTTC CATCTTCAAG GAACGATTCA 360 361 ATACCTCAAG AAGATTTCAC TCCAGAAGTG TACAGAGTTT TCCTGAACAA TCTTTGCCCT 420 421 CGACCTGAAA TTGATAACAT CTTTTCCGAA TTTGGTGCCA AAAGCAAACC ATACCTTACC 480 481 GTTGATCAGA TGATGGACTT TATCAATCTT AAGCAGAGAG ATCCCCGGCT AAATGAAATA 540 541 CTTTATCCAC CTCTAAAGCA AGAACAAGTC CAAGTATTGA TTGAGAAGTA TGAACCCAAC 600 601 AATAGCCTCG CCAAAAAAGG ACAGATATCA GTGGATGGCT TTATGCGCTA TCTAAGTGGA 660 661 GAAGAAAATG GAGTCGTTTC GCCTGAGAAA CTGGATTTGA ATGAAGATAT GTCTCAGCCC 720 721 CTTTCTCACT ATTTCATCAA TTCCTCACAC AACACCTACC TCACAGCTGG CCAGTTGGCT 780 781 GGAAACTCCT CTGTTGAGAT GTATCGCCAA GTGCTCCTGT CTGGTTGTCG CTGTGTGGAG 840 841 TTGGACTGCT GGAAGGGACG GACTGCTGAA GAGGAACCAG TCATCACCCA TGGGTTCACC 900 901 ATGACAACTG AAATATCCTT CAAGGAAGTG ATAGAAGCAA TCGCTGAGTG TGCATTTAAG 960 961 ACATCACCTT TTCCAATTCT GCTTTCATTT GAGAACCACG TAGATTCTCC AAAGCAGCAA 1020 1021 GCCAAGATGG CGGAGTATTG CCGACTGATC TTTGGAGATG CTCTTCTCAT GGAACCACTG 1080 1081 GAAAAATACC CACTGGAATC TGGAGTTCCT CTTCCAAGCC CTATGGATTT AATGTACAAA 1140 1141 ATTTTGGTGA AAAATAAGAA GAAATCGCAC AAGTCATCAG AAGGAAGTGG CAAAAAGAAG 1200 1201 CTCTCGGAAC AAGCCTCCAA CACGTACAGT GACTCCTCCA GCGTGTTTGA ACCCTCGTCT 1260 1261 CCAGGAGCCG GGGAAGCTGA TACCGAGAGT GATGATGATG ATGATGATGA TGACTGTAAA 1320 1321 AAATCTTCAA TGGATGAGGG GACTGCCGGG AGCGAGGCCA TGGCCACCGA AGAGATGTCT 1380 1381 AACCTGGTGA ACTATATTCA GCCAGTCAAG TTTGAGTCAT TTGAAATTTC AAAAAAAAGA 1440 1441 AATAGAAGTT TTGAAATGTC TTCCTTCGTG GAAACCAAAG GTCTCGAGCA GCTGACGAAA 1500 1501 TCGCCAGTGG AATTTGTAGA ATACAACAAA ATGCAGCTTA GCAGGATATA TCCAAAAGGA 1560 1561 ACCCGTGTGG ATTCATCTAA CTACATGCCT CAGCTCTTCT GGAATGCGGG TTGCCAAATG 1620 1621 GTTGCACTTA ATTTTCAAAC TGTGGACCTG GCTATGCAAA TAAATATGGG GATGTACGAA 1680 1681 TACAATGGGA AAAGTGGCTA CAGATTAAAG CCAGAGTTCA TGAGGAGACC TGACAAGCAT 1740 1741 TTTGATCCAT TCACCGAAGG CATCGTGGAT GGGATAGTGG CCAACACTTT ATCTGTCAAG 1800 1801 ATTATTTCAG GTCAGTTTCT TTCTGATAAG AAAGTCGGGA CTTATGTGGA AGTGGATATG 1860 1861 TTTGGTTTGC CTGTGGACAC GAGGAGGAAG GCGTTTAAGA CCAAAACATC ACAAGGAAAT 1920 1921 GCTGTAAATC CTGTCTGGGA AGAGGAGCCC ATTGTGTTCA AAAAGGTGGT TCTTCCTTCT 1980 1981 CTGGCCTGTT TGAGGATAGC AGTTTATGAA GAAGGGGGTA AATTTATCGG TCACCGGATC 2040 2041 TTGCCAGTAC AGGCGATTCG GCCAGGCTAT CACTACATCT GTCTGAGGAA TGAGAGGAAC 2100 2101 CAGCCTCTGA CGCTCCCAGC TGTCTTTGTC TACATAGAGG TGAAAGACTA TGTCCCAGAT 2160 2161 ACATATGCAG ATGTGATTGA AGCTTTGTCA AATCCAATAC GATATGTGAA TCTGATGGAG 2220 2221 CAAAGAGCTA AACAGTTGGC TGCTTTAACA CTGGAAGATG AGGAAGAAGT AAAGAAAGAG 2280 2281 GCTGATCCTG GGGAAACACC GTCAGAAGCT CCAAGTGAAG CCAGGACAAC TCCAGCAGAA 2340 2341 AATGGAGTGA ATCACACTAC GTCCCTGGCA CCCAAACCAC CTTCCCAGGC TCTCCACAGC 2400 2401 CAACCAGCTC CAGGTTCTGT AAAGGCACCT GCCAAAACAG AAGATCTTAT TCAGAGTGTT 2460 2461 TTAACAGAAG TGGAAGCCCA GACCATCGAA GAGCTAAAGC AGCAGAAATC GTTTGTGAAA 2520 2521 CTTCAAAAGA AACACTACAA AGAAATGAAA GACCTGGTTA AAAGACACCA CAGGAAAACC 2580 2581 ACTGACCTTA TCAAGGAACA CACTACAAAA TATAATGAAA TTCAGAATGA CTACTTGAGA 2640 2641 AGGAGGGCAG CTTTGGAGAA GACAGCCAAA AAGGATAGTA AGAAAAAATC AGATCCTAGC 2700 2701 AGTCCTGACC ATGGTTCGTC AACAATTGAG CAAGATCTTG CTGCCCTAGA TGCTGAAATG 2760 2761 ACCCAAAAGT TAATAGACTT GAAGGACAAA CAACAGCAGC AGCTGCTTAA TCTTCGACAA 2820 2821 GAGCAGTATT ATAGTGAAAA GTACCAGAAG CGAGAGCATA TTAAACTGCT TATTCAAAAG 2880 2881 TTGACGGATG TTGCTGAAGA ATGTCAGAAC AATCAGCTGA AGAAGCTCAA AGAAATCTGT 2940 2941 GAGAAAGAGA AGAAGGAATT AAAGAAGAAG ATGGACAAAA AAAGGCAGGA GAAGATAACA 3000 3001 GAAGCTAAAT CCAAAGACAA AAGTCAAATG GAAGAGGAAA AGACAGAGAT GATCCGGTCA 3060 3061 TACATCCAGG AGGTGGTGCA GTACATCAAG AGGTTAGAAG AGGCCCAAAG TAAACGGCAA 3120 3121 GAAAAACTTG TAGAGAAACA CAAGGAGATA CGTCAACAGA TACTGGACGA AAAGCCCAAG 3180 3181 CTGCAGACGG ACCTGGAGCA AGAGTACCAA GACAAGTTCA AAAGACTGCC CCTGGAGATC 3240 3241 CTGGAGTTCG TGCAGGAAGC CATGAAAGGG AAGATCAACG AAGACAGCAA TCACAGTTCT 3300 3301 GCCCCTCCCT CCCTGGCCTC AGAGCCTGGA AAAATGAACC ACAAGCCTCC CTCCAGTGAG 3360 3361 GAGCTAGAAG GAGACAACCC AGGAAAAGAG TTCGATACGC CTCTG 3405 |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Mup-2118 | Mustela putorius furo | 99.62 | 0.0 | 1951 |
| LLPS-Caf-1567 | Canis familiaris | 99.03 | 0.0 | 2090 |
| LLPS-Eqc-2422 | Equus caballus | 98.94 | 0.0 | 2080 |
| LLPS-Fec-0359 | Felis catus | 98.85 | 0.0 | 2080 |
| LLPS-Ova-3380 | Ovis aries | 98.4 | 0.0 | 1921 |
| LLPS-Caj-3855 | Callithrix jacchus | 98.33 | 0.0 | 2069 |
| LLPS-Ict-2783 | Ictidomys tridecemlineatus | 98.06 | 0.0 | 2070 |
| LLPS-Sus-4528 | Sus scrofa | 98.06 | 0.0 | 2042 |
| LLPS-Dio-2381 | Dipodomys ordii | 98.06 | 0.0 | 2063 |
| LLPS-Pat-3625 | Pan troglodytes | 97.97 | 0.0 | 2064 |
| LLPS-Pap-1709 | Pan paniscus | 97.97 | 0.0 | 2064 |
| LLPS-Hos-2648 | Homo sapiens | 97.97 | 0.0 | 2064 |
| LLPS-Cas-4103 | Carlito syrichta | 97.97 | 0.0 | 2059 |
| LLPS-Poa-4112 | Pongo abelii | 97.97 | 0.0 | 2056 |
| LLPS-Bot-2795 | Bos taurus | 97.97 | 0.0 | 2065 |
| LLPS-Nol-3886 | Nomascus leucogenys | 97.89 | 0.0 | 2060 |
| LLPS-Gog-2029 | Gorilla gorilla | 97.89 | 0.0 | 2062 |
| LLPS-Chs-2705 | Chlorocebus sabaeus | 97.76 | 0.0 | 2018 |
| LLPS-Cea-4454 | Cercocebus atys | 97.62 | 0.0 | 2054 |
| LLPS-Man-4245 | Macaca nemestrina | 97.53 | 0.0 | 2051 |
| LLPS-Mam-2333 | Macaca mulatta | 97.53 | 0.0 | 2051 |
| LLPS-Maf-1585 | Macaca fascicularis | 97.53 | 0.0 | 2051 |
| LLPS-Mal-0821 | Mandrillus leucophaeus | 97.53 | 0.0 | 2052 |
| LLPS-Fud-4097 | Fukomys damarensis | 97.27 | 0.0 | 2051 |
| LLPS-Mum-4654 | Mus musculus | 97.27 | 0.0 | 2045 |
| LLPS-Orc-2173 | Oryctolagus cuniculus | 97.24 | 0.0 | 1880 |
| LLPS-Ran-0715 | Rattus norvegicus | 97.0 | 0.0 | 2045 |
| LLPS-Cap-3246 | Cavia porcellus | 96.92 | 0.0 | 2045 |
| LLPS-Myl-1309 | Myotis lucifugus | 96.75 | 0.0 | 1754 |
| LLPS-Loa-2567 | Loxodonta africana | 95.96 | 0.0 | 1920 |
| LLPS-Aon-0848 | Aotus nancymaae | 95.51 | 0.0 | 1998 |
| LLPS-Paa-3942 | Papio anubis | 95.41 | 0.0 | 1986 |
| LLPS-Otg-0293 | Otolemur garnettii | 95.0 | 0.0 | 1851 |
| LLPS-Sah-2792 | Sarcophilus harrisii | 94.52 | 0.0 | 1807 |
| LLPS-Ora-3360 | Ornithorhynchus anatinus | 93.5 | 0.0 | 1820 |
| LLPS-Fia-1091 | Ficedula albicollis | 93.24 | 0.0 | 1856 |
| LLPS-Tag-0462 | Taeniopygia guttata | 93.14 | 0.0 | 1843 |
| LLPS-Anp-0406 | Anas platyrhynchos | 92.79 | 0.0 | 1752 |
| LLPS-Rhb-1124 | Rhinopithecus bieti | 92.69 | 0.0 | 1920 |
| LLPS-Meg-1279 | Meleagris gallopavo | 92.57 | 0.0 | 1327 |
| LLPS-Mea-3803 | Mesocricetus auratus | 91.83 | 0.0 | 1892 |
| LLPS-Gaga-3507 | Gallus gallus | 91.64 | 0.0 | 1919 |
| LLPS-Pes-3373 | Pelodiscus sinensis | 91.43 | 0.0 | 1812 |
| LLPS-Urm-1111 | Ursus maritimus | 91.11 | 0.0 | 1946 |
| LLPS-Mod-4249 | Monodelphis domestica | 89.2 | 0.0 | 1880 |
| LLPS-Anc-3419 | Anolis carolinensis | 86.65 | 0.0 | 1720 |
| LLPS-Lac-2433 | Latimeria chalumnae | 85.69 | 0.0 | 1659 |
| LLPS-Xet-3355 | Xenopus tropicalis | 84.02 | 0.0 | 1781 |
| LLPS-Leo-0947 | Lepisosteus oculatus | 80.97 | 0.0 | 1634 |
| LLPS-Asm-2907 | Astyanax mexicanus | 75.99 | 0.0 | 1573 |
| LLPS-Xim-4019 | Xiphophorus maculatus | 75.71 | 0.0 | 1318 |
| LLPS-Ten-2326 | Tetraodon nigroviridis | 73.53 | 0.0 | 1382 |
| LLPS-Scf-3528 | Scleropages formosus | 73.46 | 0.0 | 1508 |
| LLPS-Orn-3040 | Oreochromis niloticus | 72.61 | 0.0 | 1565 |
| LLPS-Tar-1801 | Takifugu rubripes | 72.33 | 0.0 | 1589 |
| LLPS-Pof-0838 | Poecilia formosa | 72.0 | 0.0 | 1545 |
| LLPS-Scm-1525 | Scophthalmus maximus | 71.5 | 0.0 | 1561 |
| LLPS-Orl-3537 | Oryzias latipes | 71.22 | 0.0 | 1543 |
| LLPS-Gaa-3281 | Gasterosteus aculeatus | 70.84 | 0.0 | 1507 |
| LLPS-Icp-2505 | Ictalurus punctatus | 70.56 | 0.0 | 1515 |
| LLPS-Dar-1156 | Danio rerio | 46.2 | 2e-34 | 147 |
| LLPS-Tut-0755 | Tursiops truncatus | 39.6 | 2e-45 | 180 |
| LLPS-Cis-1090 | Ciona savignyi | 32.31 | 1e-83 | 292 |
| LLPS-Scj-0190 | Schizosaccharomyces japonicus | 28.06 | 5e-55 | 211 |