• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-1105
DNAJA1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DnaJ heat shock protein family (Hsp40) member A1
Gene Name: DNAJA1
Ensembl Gene: ENSAMEG00000007589.1
Ensembl Protein: ENSAMEP00000008049.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSAMET00000008382.1ENSAMEP00000008049.1
UniProtG1LM67, G1LM67_AILME
GeneBankACTA01170091

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVKETTYYDV  LGVKPNATQE  ELKKAYRKLA  LKYHPDKNPN  EGEKFKQISQ  AYEVLSDAKK  60
61    RELYDKGGEQ  AIKEGGAGGG  FGSPMDIFDM  FFGGGGRMQR  ERRGKNVVHQ  LSVTLEDLYN  120
121   GATRKLALQK  NVICDKCEGR  GGKKGAVECC  PNCRGTGMQI  RIHQIGPGMV  QQIQSVCMEC  180
181   QGHGERISPK  DRCKSCNGRK  IVREKKILEV  HIDKGMKDGQ  KITFHGEGDQ  EPGLESGDII  240
241   IVLDQKDHAV  FTRKREDLFM  CMDIQLVEAL  CGFQKPISTL  DNRTIVITSH  PGQIVKHGDI  300
301   KCVLNEGMPI  YRRPYEKGRL  IIEFKVNFPE  NGFLSPDKLS  LLEKLLPERK  EVEETDEMDQ  360
361   VELVDFDPNQ  ERRRHYNGEA  YEDDEHHPRG  GVQCQTS  397
Nucleotide CDS Sequence (FASTA)
1     ATGGTGAAAG  AAACCACTTA  CTATGATGTT  TTGGGGGTCA  AACCCAATGC  CACCCAGGAG  60
61    GAATTGAAAA  AGGCCTACAG  GAAACTGGCC  TTGAAGTACC  ACCCTGATAA  GAATCCAAAT  120
121   GAAGGAGAGA  AGTTTAAACA  GATTTCTCAA  GCTTATGAAG  TACTCTCTGA  TGCAAAGAAA  180
181   AGGGAATTAT  ATGACAAAGG  AGGTGAACAG  GCAATTAAAG  AAGGCGGAGC  TGGTGGTGGT  240
241   TTTGGCTCCC  CCATGGACAT  CTTTGATATG  TTTTTTGGAG  GAGGAGGAAG  GATGCAGAGA  300
301   GAGAGGAGAG  GTAAAAATGT  TGTGCATCAG  CTCTCAGTAA  CCTTAGAAGA  TTTATATAAT  360
361   GGTGCAACAA  GAAAACTAGC  TCTGCAGAAG  AATGTGATTT  GTGATAAATG  TGAAGGCCGA  420
421   GGTGGTAAGA  AAGGAGCAGT  TGAATGTTGT  CCCAATTGCC  GAGGTACTGG  AATGCAAATA  480
481   AGAATTCATC  AGATAGGACC  TGGAATGGTT  CAGCAAATTC  AGTCTGTGTG  CATGGAGTGC  540
541   CAGGGCCATG  GGGAACGGAT  CAGTCCTAAA  GATAGATGTA  AAAGCTGCAA  TGGAAGGAAG  600
601   ATAGTTCGAG  AGAAGAAGAT  TCTAGAAGTT  CATATTGACA  AAGGCATGAA  AGATGGCCAG  660
661   AAGATAACAT  TCCATGGTGA  AGGAGACCAA  GAACCAGGAC  TGGAATCAGG  AGATATTATC  720
721   ATTGTTTTAG  ATCAGAAGGA  CCATGCTGTT  TTTACTCGAA  AACGAGAAGA  CCTTTTCATG  780
781   TGTATGGACA  TACAGCTGGT  TGAAGCACTG  TGTGGCTTTC  AAAAGCCAAT  ATCTACTCTT  840
841   GACAACCGAA  CCATCGTCAT  CACCTCTCAT  CCAGGTCAAA  TTGTCAAGCA  TGGAGATATC  900
901   AAGTGTGTGC  TAAATGAAGG  CATGCCAATT  TATCGTAGAC  CGTATGAGAA  GGGTCGTCTA  960
961   ATCATCGAGT  TTAAGGTAAA  CTTTCCTGAG  AATGGTTTTC  TCTCTCCTGA  TAAACTCTCT  1020
1021  TTGCTGGAGA  AACTCCTACC  TGAGAGAAAG  GAAGTGGAAG  AGACTGATGA  AATGGACCAG  1080
1081  GTAGAACTGG  TGGACTTTGA  TCCAAATCAG  GAAAGACGGC  GCCATTACAA  TGGGGAAGCC  1140
1141  TACGAGGATG  ATGAACATCA  TCCCAGGGGT  GGGGTTCAGT  GTCAGACCTC  TTAA  1194

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Paa-4407Papio anubis99.240.0 712
LLPS-Mal-1663Mandrillus leucophaeus99.240.0 712
LLPS-Dio-1511Dipodomys ordii99.240.0 712
LLPS-Caj-3191Callithrix jacchus99.240.0 712
LLPS-Fud-1691Fukomys damarensis99.240.0 712
LLPS-Gog-1024Gorilla gorilla99.240.0 712
LLPS-Sus-2137Sus scrofa99.240.0 712
LLPS-Cea-1141Cercocebus atys99.240.0 712
LLPS-Maf-2696Macaca fascicularis99.240.0 712
LLPS-Nol-1699Nomascus leucogenys99.240.0 712
LLPS-Ict-4008Ictidomys tridecemlineatus99.240.0 712
LLPS-Mam-2468Macaca mulatta99.240.0 712
LLPS-Cap-0886Cavia porcellus99.240.0 712
LLPS-Eqc-0484Equus caballus99.240.0 712
LLPS-Poa-0662Pongo abelii99.240.0 712
LLPS-Caf-2159Canis familiaris99.240.0 712
LLPS-Orc-1647Oryctolagus cuniculus99.240.0 712
LLPS-Man-3730Macaca nemestrina99.240.0 712
LLPS-Fec-1011Felis catus99.240.0 712
LLPS-Hos-0554Homo sapiens99.240.0 712
LLPS-Pat-0504Pan troglodytes99.240.0 712
LLPS-Pap-0640Pan paniscus99.240.0 712
LLPS-Bot-0920Bos taurus98.990.0 711
LLPS-Tut-1773Tursiops truncatus98.990.0 711
LLPS-Chs-1617Chlorocebus sabaeus98.974e-175 498
LLPS-Rhb-0770Rhinopithecus bieti98.780.0 570
LLPS-Myl-2259Myotis lucifugus98.740.0 710
LLPS-Ran-0407Rattus norvegicus98.740.0 710
LLPS-Mum-0000Mus musculus98.740.0 710
LLPS-Ova-2681Ovis aries98.490.0 708
LLPS-Urm-1101Ursus maritimus98.350.0 637
LLPS-Loa-0037Loxodonta africana97.990.0 681
LLPS-Mod-1342Monodelphis domestica95.990.0 667
LLPS-Sah-1512Sarcophilus harrisii95.970.0 689
LLPS-Ora-3154Ornithorhynchus anatinus94.870.0 650
LLPS-Pes-0069Pelodiscus sinensis94.190.0 667
LLPS-Aon-0673Aotus nancymaae93.980.0 588
LLPS-Anc-0729Anolis carolinensis92.440.0 665
LLPS-Mup-3433Mustela putorius furo91.440.0 640
LLPS-Gaga-2502Gallus gallus90.680.0 624
LLPS-Anp-0964Anas platyrhynchos90.440.0 541
LLPS-Fia-1851Ficedula albicollis90.170.0 572
LLPS-Tag-0012Taeniopygia guttata88.770.0 570
LLPS-Otg-2428Otolemur garnettii88.660.0 614
LLPS-Xet-2236Xenopus tropicalis85.250.0 595
LLPS-Lac-2208Latimeria chalumnae78.150.0 526
LLPS-Cas-0877Carlito syrichta76.597e-175 500
LLPS-Leo-0674Lepisosteus oculatus73.130.0 517
LLPS-Orn-1080Oreochromis niloticus71.461e-177 508
LLPS-Mea-1977Mesocricetus auratus71.115e-180 514
LLPS-Meg-2215Meleagris gallopavo71.111e-180 516
LLPS-Icp-2416Ictalurus punctatus70.781e-173 498
LLPS-Tar-0281Takifugu rubripes70.65e-172 494
LLPS-Scf-0099Scleropages formosus70.534e-168 484
LLPS-Scm-2878Scophthalmus maximus70.455e-171 491
LLPS-Dar-1752Danio rerio69.95e-172 494
LLPS-Orl-2802Oryzias latipes69.447e-172 493
LLPS-Pof-1786Poecilia formosa69.442e-168 485
LLPS-Xim-0870Xiphophorus maculatus69.194e-168 484
LLPS-Gaa-1046Gasterosteus aculeatus68.872e-176 505
LLPS-Ten-1671Tetraodon nigroviridis68.691e-170 490
LLPS-Asm-2606Astyanax mexicanus66.924e-166 479
LLPS-Cii-1762Ciona intestinalis62.695e-155 451
LLPS-Cis-0187Ciona savignyi61.692e-155 452
LLPS-Drm-0042Drosophila melanogaster58.273e-135 400
LLPS-Orbr-0183Oryza brachyantha52.073e-107 329
LLPS-Brd-0733Brachypodium distachyon52.032e-105 325
LLPS-Org-1795Oryza glaberrima51.771e-106 328
LLPS-Orni-0984Oryza nivara51.646e-106 330
LLPS-Orgl-0392Oryza glumaepatula51.371e-106 327
LLPS-Ori-0340Oryza indica51.377e-107 328
LLPS-Orb-1588Oryza barthii51.378e-106 332
LLPS-Orr-0534Oryza rufipogon51.376e-106 329
LLPS-Hov-0246Hordeum vulgare51.353e-107 331
LLPS-Orm-0513Oryza meridionalis51.095e-106 327
LLPS-Ors-0598Oryza sativa51.092e-106 327
LLPS-Tra-0049Triticum aestivum51.085e-107 328
LLPS-Coc-0255Corchorus capsularis51.021e-106 327
LLPS-Sob-1232Sorghum bicolor50.891e-106 328
LLPS-Tru-0012Triticum urartu50.541e-107 330
LLPS-Osl-0083Ostreococcus lucimarinus50.499e-112 341
LLPS-Sei-0984Setaria italica50.129e-107 328
LLPS-Hea-2102Helianthus annuus50.129e-109 333
LLPS-Cus-0973Cucumis sativus50.09e-111 338
LLPS-Cae-0641Caenorhabditis elegans49.881e-105 324
LLPS-Mua-0207Musa acuminata49.881e-107 330
LLPS-Php-1822Physcomitrella patens49.883e-111 340
LLPS-Pot-0297Populus trichocarpa49.755e-106 326
LLPS-Vir-1577Vigna radiata49.634e-107 328
LLPS-Sem-0158Selaginella moellendorffii49.512e-108 332
LLPS-Mae-0017Manihot esculenta49.511e-105 325
LLPS-Dac-0187Daucus carota49.391e-108 332
LLPS-Nia-0399Nicotiana attenuata49.392e-109 335
LLPS-Zem-1078Zea mays49.273e-108 332
LLPS-Sot-1789Solanum tuberosum49.265e-108 331
LLPS-Thc-0735Theobroma cacao49.023e-108 332
LLPS-Glm-0078Glycine max49.013e-108 332
LLPS-Via-1759Vigna angularis48.95e-109 334
LLPS-Gor-0009Gossypium raimondii48.897e-108 331
LLPS-Phv-1532Phaseolus vulgaris48.655e-106 326
LLPS-Viv-0417Vitis vinifera48.641e-107 330
LLPS-Sol-0174Solanum lycopersicum48.527e-108 331
LLPS-Amt-0590Amborella trichopoda48.393e-106 327