• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Aim-1062
CDC25A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cell division cycle 25A
Gene Name: CDC25A
Ensembl Gene: ENSAMEG00000001398.1
Ensembl Protein: ENSAMEP00000001504.1
Organism: Ailuropoda melanoleuca
Taxa ID: 9646
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole body, P-body, OthersPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     AGSSPAPVGD  RQLSPACASP  PCVDLREGVM  QRWPTAAASG  GLSPVTNLTV  TMDQLQGLGS  60
61    EYEQPLEVRN  SSLQRMGSSE  STDSGFCLDS  PGPLDSKENL  ENPMRRISFL  PQKLLGCSPA  120
121   LKRSHSDSLD  HDVFQLMDQD  ENKENEAFEF  KKPVRPASRG  CLHFHGLEES  KDLFTQRQNS  180
181   APARMLSSNE  RDGGEPGNFV  PLFMPQSPVT  ATLSDEDDGF  MDLLDGENLK  NDEETPSCMA  240
241   SLWTAPLVMR  RTTNLGNRCK  LFDSSSTCSS  ITRSVLKRPE  RSQEEHPPAN  SKRRKSMAGA  300
301   SPAEAASPEK  PQEILHHSLS  LASSPKGTIE  NILDNDPRDL  IGDFSKGYLF  HTVAGKHQDL  360
361   KYISPEIMAS  VLNGKFANLI  KEFVIIDCRY  PYEYEGGHIK  GAVNLHMEEE  VEDFLLKKPI  420
421   VPTDGKRVIV  VFHCEFSSER  GPRMCRYVRE  RDRLGNEYPK  LHYPELYVLK  GGYKEFFLKC  480
481   QSHCEPPGYR  PMHHEDFKED  LKKFRTKSRT  WAGEKSKREM  YSRLKKL  527
Nucleotide CDS Sequence (FASTA)
1     GCTGGGTCCA  GCCCGGCCCC  AGTGGGGGAC  AGACAGCTGT  CTCCAGCGTG  CGCGTCCCCT  60
61    CCGTGTGTGG  ACCTCCGGGA  AGGGGTTATG  CAGCGGTGGC  CCACAGCGGC  AGCCTCCGGG  120
121   GGCCTGTCGC  CTGTCACCAA  CCTGACGGTC  ACCATGGACC  AGCTGCAGGG  GCTGGGCAGT  180
181   GAATATGAAC  AGCCGCTGGA  GGTGAGAAAC  AGCAGTCTGC  AGAGAATGGG  CTCCTCTGAG  240
241   TCAACCGATT  CAGGCTTCTG  TCTGGATTCT  CCTGGGCCCT  TGGATAGTAA  AGAAAACCTT  300
301   GAAAATCCCA  TGAGGAGAAT  AAGTTTCCTG  CCTCAGAAGC  TCTTGGGATG  TAGCCCAGCT  360
361   CTGAAGAGGA  GCCATTCTGA  TTCTCTTGAC  CATGATGTCT  TTCAACTGAT  GGACCAGGAT  420
421   GAGAACAAGG  AAAACGAAGC  CTTTGAGTTT  AAGAAGCCAG  TAAGACCGGC  ATCTCGTGGC  480
481   TGCCTGCATT  TTCATGGACT  TGAGGAGAGT  AAAGATCTCT  TCACACAGAG  GCAGAACTCT  540
541   GCCCCAGCTC  GGATGCTTTC  CTCTAATGAA  AGAGATGGCG  GCGAGCCAGG  GAATTTCGTT  600
601   CCTCTTTTTA  TGCCCCAATC  CCCTGTGACG  GCCACTTTGT  CTGATGAGGA  TGATGGCTTC  660
661   ATGGACCTTC  TTGATGGAGA  GAATCTGAAG  AACGATGAAG  AGACCCCATC  GTGCATGGCA  720
721   AGCCTCTGGA  CGGCTCCCCT  TGTCATGAGA  AGAACTACAA  ACCTTGGCAA  TCGATGCAAG  780
781   CTGTTTGACT  CTTCTTCCAC  GTGTAGCTCC  ATCACCCGGT  CAGTGTTAAA  AAGACCAGAA  840
841   CGATCTCAAG  AGGAGCACCC  GCCTGCAAAT  TCAAAGCGGA  GAAAGAGCAT  GGCTGGGGCC  900
901   AGTCCCGCTG  AGGCAGCCAG  TCCAGAGAAG  CCCCAGGAGA  TTCTACATCA  CTCTTTATCC  960
961   CTGGCATCTT  CCCCAAAGGG  GACCATTGAG  AACATTTTGG  ATAATGACCC  AAGGGACCTT  1020
1021  ATAGGAGACT  TCTCCAAGGG  TTATCTCTTT  CATACAGTTG  CTGGGAAGCA  TCAGGATTTA  1080
1081  AAATACATCT  CTCCAGAAAT  TATGGCATCT  GTTTTAAATG  GCAAATTTGC  CAACCTCATT  1140
1141  AAAGAATTTG  TTATCATTGA  CTGCCGATAC  CCATATGAAT  ATGAGGGTGG  CCACATCAAG  1200
1201  GGTGCGGTGA  ACTTGCACAT  GGAAGAGGAG  GTTGAGGACT  TCTTGCTCAA  GAAGCCTATC  1260
1261  GTACCTACTG  ATGGCAAGCG  CGTCATTGTC  GTGTTCCACT  GCGAGTTCTC  TTCCGAGCGA  1320
1321  GGCCCTCGCA  TGTGCCGGTA  TGTGAGAGAG  CGAGATCGGC  TTGGTAACGA  GTACCCCAAG  1380
1381  CTGCACTACC  CCGAGCTGTA  TGTCCTGAAG  GGCGGGTACA  AGGAGTTCTT  CCTGAAATGC  1440
1441  CAGTCTCACT  GTGAGCCCCC  CGGCTACCGG  CCCATGCACC  ACGAGGACTT  CAAAGAAGAC  1500
1501  CTGAAGAAGT  TCCGCACCAA  GAGCCGGACC  TGGGCCGGGG  AAAAGAGCAA  AAGGGAGATG  1560
1561  TACAGCCGTC  TGAAGAAGCT  GTGA  1584

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mup-0003Mustela putorius furo96.850.0 867
LLPS-Caf-3816Canis familiaris92.350.0 898
LLPS-Orc-3039Oryctolagus cuniculus91.930.0 847
LLPS-Fec-1852Felis catus91.010.0 882
LLPS-Loa-3881Loxodonta africana90.710.0 845
LLPS-Eqc-2918Equus caballus90.630.0 888
LLPS-Sus-0729Sus scrofa89.870.0 875
LLPS-Cas-1094Carlito syrichta88.590.0 858
LLPS-Otg-2168Otolemur garnettii88.170.0 863
LLPS-Bot-3842Bos taurus88.00.0 858
LLPS-Hos-3314Homo sapiens87.790.0 863
LLPS-Gog-1114Gorilla gorilla87.790.0 862
LLPS-Nol-1665Nomascus leucogenys87.60.0 861
LLPS-Mal-2475Mandrillus leucophaeus87.60.0 855
LLPS-Man-2380Macaca nemestrina87.40.0 853
LLPS-Pap-0654Pan paniscus87.40.0 860
LLPS-Pat-1983Pan troglodytes87.40.0 860
LLPS-Ova-0162Ovis aries87.290.0 849
LLPS-Poa-0391Pongo abelii87.210.0 856
LLPS-Paa-1584Papio anubis87.210.0 851
LLPS-Caj-3820Callithrix jacchus87.210.0 850
LLPS-Cea-3861Cercocebus atys87.210.0 852
LLPS-Myl-2456Myotis lucifugus85.810.0 749
LLPS-Fud-0067Fukomys damarensis84.650.0 744
LLPS-Dio-3040Dipodomys ordii82.890.0 806
LLPS-Ict-2425Ictidomys tridecemlineatus81.680.0 806
LLPS-Cap-3051Cavia porcellus81.440.0 804
LLPS-Anc-3729Anolis carolinensis81.411e-117 353
LLPS-Maf-2092Macaca fascicularis81.30.0 781
LLPS-Mam-1286Macaca mulatta81.260.0 768
LLPS-Mum-1341Mus musculus80.530.0 764
LLPS-Ran-1372Rattus norvegicus80.080.0 791
LLPS-Rhb-3783Rhinopithecus bieti77.480.0 716
LLPS-Sah-0324Sarcophilus harrisii77.190.0 667
LLPS-Aon-2391Aotus nancymaae74.480.0 672
LLPS-Mod-4120Monodelphis domestica73.330.0 683
LLPS-Ora-1519Ornithorhynchus anatinus69.56e-178 515
LLPS-Anp-2575Anas platyrhynchos66.450.0 568
LLPS-Pes-1304Pelodiscus sinensis65.760.0 582
LLPS-Meg-0874Meleagris gallopavo62.710.0 536
LLPS-Fia-1488Ficedula albicollis61.340.0 531
LLPS-Gaga-1143Gallus gallus59.560.0 549
LLPS-Tag-3208Taeniopygia guttata59.160.0 538
LLPS-Urm-3536Ursus maritimus58.764e-75 252
LLPS-Chs-0713Chlorocebus sabaeus58.762e-72 244
LLPS-Scf-0942Scleropages formosus54.369e-64 222
LLPS-Lac-2338Latimeria chalumnae53.477e-103 328
LLPS-Leo-1313Lepisosteus oculatus51.376e-56 198
LLPS-Ere-0064Erinaceus europaeus50.811e-103 330
LLPS-Xet-3337Xenopus tropicalis50.07e-159 470
LLPS-Mea-3076Mesocricetus auratus48.247e-2094.0
LLPS-Pof-2326Poecilia formosa48.181e-131 402
LLPS-Drm-1479Drosophila melanogaster47.897e-51 186
LLPS-Scm-2102Scophthalmus maximus47.758e-129 395
LLPS-Xim-0245Xiphophorus maculatus47.633e-129 395
LLPS-Cis-1715Ciona savignyi47.568e-59 205
LLPS-Asm-2568Astyanax mexicanus47.232e-126 388
LLPS-Orn-0988Oreochromis niloticus47.224e-134 408
LLPS-Dar-3685Danio rerio47.072e-127 390
LLPS-Icp-0642Ictalurus punctatus47.01e-133 407
LLPS-Tar-0819Takifugu rubripes45.942e-124 384
LLPS-Orl-2065Oryzias latipes45.883e-128 393
LLPS-Ten-3559Tetraodon nigroviridis44.892e-113 355
LLPS-Tut-1771Tursiops truncatus43.832e-116 362
LLPS-Trv-1291Trichoderma virens43.71e-29 126
LLPS-Trr-1437Trichoderma reesei43.71e-29 126
LLPS-Fuo-1225Fusarium oxysporum42.381e-29 126
LLPS-Fuv-1288Fusarium verticillioides42.382e-29 125
LLPS-Mel-0948Melampsora laricipopulina41.383e-28 114
LLPS-Pug-0602Puccinia graminis41.14e-30 129
LLPS-Fus-0922Fusarium solani41.064e-28 122
LLPS-Ast-0808Aspergillus terreus41.016e-28 121
LLPS-Scp-1651Schizosaccharomyces pombe40.353e-33 137
LLPS-Gaa-0352Gasterosteus aculeatus40.245e-90 293
LLPS-Asni-0556Aspergillus niger40.142e-27 120
LLPS-Asf-0660Aspergillus flavus40.02e-25 114
LLPS-Aso-0595Aspergillus oryzae40.02e-25 114
LLPS-Mao-1582Magnaporthe oryzae40.04e-27 119
LLPS-Cae-0402Caenorhabditis elegans39.071e-22 102
LLPS-Dos-0570Dothistroma septosporum38.933e-26 116
LLPS-Cogr-0593Colletotrichum graminicola38.322e-28 122
LLPS-Map-0514Magnaporthe poae38.156e-27 118
LLPS-Gag-0961Gaeumannomyces graminis38.151e-27 120
LLPS-Asn-0942Aspergillus nidulans37.841e-28 123
LLPS-Coo-1399Colletotrichum orbiculare36.811e-28 123
LLPS-Spr-0504Sporisorium reilianum36.654e-29 126
LLPS-Asfu-0919Aspergillus fumigatus35.982e-26 117
LLPS-Nef-0121Neosartorya fischeri35.987e-27 116
LLPS-Asc-1473Aspergillus clavatus35.441e-28 122
LLPS-Zyt-1162Zymoseptoria tritici34.723e-25 113
LLPS-Crn-0036Cryptococcus neoformans34.437e-0959.7
LLPS-Usm-1027Ustilago maydis34.039e-28 122
LLPS-Asg-1021Ashbya gossypii33.94e-27 117
LLPS-Phn-1424Phaeosphaeria nodorum32.626e-26 115