DrLLPS - Data resource of LLPS

Disorder▼
- IUPred2A
- MobiDB
Domain▼
PTM▼
Variation▼
Mutation▼
- CGAP
Interaction▼
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Drug▼
Physicochemical▼
- Compute pI/Mw
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Function▼
- CellMarker
Proteomics▼
Structure▼
Localization▼
- COMPARTMENTS
Expression▼
Element▼
Methylation▼

Pfam
InterPro
LCReXXXplorer
CDD
PROSITE
Gene3D

Pfam
Pfam ID	Family
PF12796	Ank_2
PF01412	ArfGap
PF00169	PH

InterPro
InterPro ID	Name
IPR027267	AH/BAR_dom_sf
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom
IPR036770	Ankyrin_rpt-contain_sf
IPR037278	ARFGAP/RecO
IPR001164	ArfGAP_dom
IPR038508	ArfGAP_dom_sf
IPR011993	PH-like_dom_sf
IPR001849	PH_domain

LCR-eXXXplorer
Start	End	Method
27	42	SEG

CDD
Hit Type	PSSM-ID	From	To	E-value	Bitscore	Accession	Short Name	Incomplete	Superfamily
Specific	153322	18	217	2.95366e-131	388.59	Cd07638	BAR_ACAP2	-	Cl12013
Superfamily	353336	18	217	2.95366e-131	388.59	Cl12013	BAR superfamily	-	-
Specific	318867	5	238	4.31527e-111	337.986	Pfam16746	BAR_3	-	Cl12013
Non-specific	153287	18	217	9.6004e-110	333.115	Cd07603	BAR_ACAPs	-	Cl12013
Non-specific	153321	18	217	2.85805e-93	290.364	Cd07637	BAR_ACAP3	-	Cl12013
Specific	350076	399	513	1.20571e-83	261.843	Cd08851	ArfGap_ACAP2	-	Cl28907
Superfamily	355783	399	513	1.20571e-83	261.843	Cl28907	ArfGap superfamily	-	-
Non-specific	350064	399	513	1.13768e-77	245.631	Cd08835	ArfGap_ACAP	-	Cl28907
Non-specific	350075	399	513	7.04802e-70	225.208	Cd08850	ArfGap_ACAP3	-	Cl28907
Non-specific	350077	401	515	3.2354e-66	215.594	Cd08852	ArfGap_ACAP1	-	Cl28907
Non-specific	153323	18	216	4.68402e-63	209.77	Cd07639	BAR_ACAP1	-	Cl12013
Specific	270070	269	365	1.68549e-58	193.59	Cd13250	PH_ACAP	-	Cl17171
Superfamily	354315	269	365	1.68549e-58	193.59	Cl17171	PH-like superfamily	-	-
Non-specific	350058	402	507	1.35276e-56	188.862	Cd08204	ArfGap	-	Cl28907
Specific	214518	402	518	1.75778e-55	186.008	Smart00105	ArfGap	-	Cl29885
Superfamily	356761	402	518	1.75778e-55	186.008	Cl29885	ArfGap superfamily	-	-
Specific	307528	399	515	4.36602e-54	182.059	Pfam01412	ArfGap	-	Cl29885
Non-specific	350065	401	508	3.94934e-49	168.238	Cd08836	ArfGap_AGAP	-	Cl28907
Non-specific	350063	400	513	6.20804e-45	156.997	Cd08834	ArfGap_ASAP	-	Cl28907
Non-specific	350068	409	507	5.11695e-39	139.714	Cd08839	ArfGap_SMAP	-	Cl28907
Non-specific	350061	401	507	3.87416e-38	137.392	Cd08832	ArfGap_ADAP	-	Cl28907
Non-specific	350078	401	507	1.32538e-37	135.908	Cd08853	ArfGap_AGAP2	-	Cl28907
Non-specific	227651	387	624	2.75258e-37	142.225	COG5347	COG5347	C	Cl34987
Superfamily	227651	387	624	2.75258e-37	142.225	Cl34987	COG5347 superfamily	C	-
Non-specific	350080	401	507	4.11152e-37	134.411	Cd08855	ArfGap_AGAP3	-	Cl28907
Non-specific	350087	405	515	7.58153e-37	134.204	Cd17900	ArfGap_ASAP3	-	Cl28907
Non-specific	350079	401	507	2.95868e-35	129.36	Cd08854	ArfGap_AGAP1	-	Cl28907
Non-specific	350074	402	515	1.646e-33	124.704	Cd08849	ArfGap_ASAP2	-	Cl28907
Non-specific	350062	414	507	2.01181e-32	121.255	Cd08833	ArfGap_GIT	-	Cl28907
Non-specific	350073	399	515	1.41719e-31	119.37	Cd08848	ArfGap_ASAP1	-	Cl28907
Non-specific	350059	402	507	3.89551e-30	114.902	Cd08830	ArfGap_ArfGap1	-	Cl28907
Non-specific	350066	402	512	1.19275e-29	113.625	Cd08837	ArfGap_ARAP	-	Cl28907
Non-specific	350084	402	467	7.15072e-28	108.369	Cd08959	ArfGap_ArfGap1_like	C	Cl28907
Non-specific	350083	411	511	8.95328e-28	107.766	Cd08859	ArfGap_SMAP2	-	Cl28907
Non-specific	350060	402	473	2.38967e-25	101.084	Cd08831	ArfGap_ArfGap2_3_like	C	Cl28907
Non-specific	350069	402	507	9.27476e-25	99.3084	Cd08843	ArfGap_ADAP1	-	Cl28907
Non-specific	350088	403	512	2.21685e-24	98.3458	Cd17901	ArfGap_ARAP1	-	Cl28907
Non-specific	153271	27	216	7.05793e-24	99.8262	Cd07307	BAR	-	Cl12013
Non-specific	350070	409	507	6.70985e-23	94.0643	Cd08844	ArfGap_ADAP2	-	Cl28907
Non-specific	350072	414	507	8.97628e-23	93.5469	Cd08847	ArfGap_GIT2	-	Cl28907
Non-specific	350081	411	512	1.98515e-22	93.0483	Cd08856	ArfGap_ARAP2	-	Cl28907
Non-specific	350089	409	512	3.55962e-22	92.2789	Cd17902	ArfGap_ARAP3	-	Cl28907
Non-specific	350086	399	472	2.49232e-20	87.041	Cd09029	ArfGap_ArfGap2	C	Cl28907
Non-specific	350067	409	514	1.08703e-19	84.9391	Cd08838	ArfGap_AGFG	-	Cl28907
Non-specific	153319	22	216	2.3529e-19	86.9751	Cd07635	BAR_GRAF2	-	Cl12013
Non-specific	350085	402	472	2.43425e-19	84.3474	Cd09028	ArfGap_ArfGap3	C	Cl28907
Non-specific	153290	19	216	1.45821e-18	84.4646	Cd07606	BAR_SFC_plant	-	Cl12013
Non-specific	153286	38	217	5.42908e-18	83.1337	Cd07602	BAR_RhoGAP_OPHN1-like	-	Cl12013
Specific	214574	267	361	6.61955e-18	79.5148	Smart00233	PH	-	Cl17171
Non-specific	350071	408	507	9.89746e-18	79.3761	Cd08846	ArfGap_GIT1	-	Cl28907
Non-specific	178661	391	473	1.72014e-17	85.2917	PLN03114	PLN03114	C	Cl28906
Superfamily	178661	391	473	1.72014e-17	85.2917	Cl28906	PLN03114 superfamily	C	-
Non-specific	153318	30	216	5.45122e-17	80.0742	Cd07634	BAR_GAP10-like	-	Cl12013
Non-specific	275388	269	356	2.6595e-16	74.5013	Cd00821	PH	-	Cl17171
Specific	333896	267	357	1.99037e-15	72.5699	Pfam00169	PH	-	Cl25538
Superfamily	333896	267	357	1.99037e-15	72.5699	Cl25538	PH superfamily	-	-
Non-specific	153320	32	216	4.86047e-15	74.3247	Cd07636	BAR_GRAF	-	Cl12013
Non-specific	270095	270	369	7.8547e-15	70.809	Cd13276	PH_AtPH1	-	Cl17171
Non-specific	153285	18	221	3.49571e-13	69.1672	Cd07601	BAR_APPL	-	Cl12013
Non-specific	269954	259	361	1.22662e-12	65.0282	Cd01252	PH_GRP1-like	-	Cl17171
Non-specific	269977	270	357	3.96867e-12	62.7269	Cd10573	PH_DAPP1	-	Cl17171
Non-specific	270110	265	356	8.42487e-12	62.258	Cd13298	PH1_PH_fungal	-	Cl17171
Non-specific	140343	669	753	1.74567e-11	67.6158	PTZ00322	PTZ00322	C	Cl31426
Superfamily	140343	669	753	1.74567e-11	67.6158	Cl31426	PTZ00322 superfamily	C	-
Non-specific	153315	72	224	2.74979e-11	63.5679	Cd07631	BAR_APPL1	N	Cl12013
Non-specific	270067	271	356	3.36985e-11	61.2329	Cd13247	BAR-PH_APPL	N	Cl17171
Non-specific	153316	18	212	3.98621e-11	63.123	Cd07632	BAR_APPL2	-	Cl12013
Specific	338493	672	753	4.7912e-11	59.735	Pfam12796	Ank_2	-	Cl38371
Superfamily	338493	672	753	4.7912e-11	59.735	Cl38371	Ank_2 superfamily	-	-
Non-specific	338493	637	731	4.9334e-11	59.3498	Pfam12796	Ank_2	-	Cl38371
Non-specific	241436	270	358	1.42996e-10	58.4629	Cd13282	PH1_PLEKHH1_PLEKHH2	-	Cl17171
Specific	223738	625	754	3.57345e-10	60.9935	COG0666	ANKYR	N	Cl34000
Superfamily	223738	625	754	3.57345e-10	60.9935	Cl34000	ANKYR superfamily	N	-
Non-specific	270113	266	360	3.70133e-10	57.3822	Cd13301	PH1_Pleckstrin_2	-	Cl17171
Non-specific	270105	269	357	4.83772e-10	57.6327	Cd13288	PH_Ses	-	Cl17171
Non-specific	153317	22	216	1.32614e-09	58.4762	Cd07633	BAR_OPHN1	-	Cl12013
Non-specific	222984	637	762	2.21453e-09	60.0638	PHA03100	PHA03100	NC	Cl33710
Superfamily	222984	637	762	2.21453e-09	60.0638	Cl33710	PHA03100 superfamily	NC	-
Non-specific	269953	268	355	2.88431e-09	55.03	Cd01249	BAR-PH_GRAF_family	-	Cl17171
Non-specific	270092	265	361	6.62062e-09	53.8383	Cd13273	PH_SWAP-70	-	Cl17171
Non-specific	153288	22	220	7.88189e-09	56.267	Cd07604	BAR_ASAPs	-	Cl12013
Non-specific	270075	262	356	1.11451e-08	53.5711	Cd13255	PH_TAAP2-like	-	Cl17171
Non-specific	270098	283	359	2.16454e-08	52.2614	Cd13280	PH_SIP3	-	Cl17171
Non-specific	222980	635	766	2.43326e-08	56.9567	PHA03095	PHA03095	C	Cl33707
Superfamily	222980	635	766	2.43326e-08	56.9567	Cl33707	PHA03095 superfamily	C	-
Non-specific	222980	635	751	4.62379e-08	56.1863	PHA03095	PHA03095	NC	Cl33707
Non-specific	270068	267	355	4.83103e-08	51.5042	Cd13248	PH_PEPP1_2_3	-	Cl17171
Non-specific	350082	402	512	8.24822e-08	51.193	Cd08857	ArfGap_AGFG1	-	Cl28907
Non-specific	269939	271	361	1.86989e-07	49.5139	Cd01233	PH_KIFIA_KIFIB	-	Cl17171
Non-specific	178677	390	549	2.41497e-07	54.0133	PLN03131	PLN03131	C	Cl28909
Superfamily	178677	390	549	2.41497e-07	54.0133	Cl28909	PLN03131 superfamily	C	-
Non-specific	153324	19	220	2.93835e-07	51.9223	Cd07640	BAR_ASAP3	-	Cl12013
Non-specific	270083	266	356	3.53635e-07	49.3043	Cd13263	PH_RhoGap25-like	-	Cl17171
Non-specific	275402	267	357	4.347e-07	49.1574	Cd13215	PH-GRAM1_AGT26	-	Cl17171
Non-specific	178666	390	549	5.79266e-07	52.9252	PLN03119	PLN03119	C	Cl28908
Superfamily	178666	390	549	5.79266e-07	52.9252	Cl28908	PLN03119 superfamily	C	-
Non-specific	153326	35	220	8.88797e-07	50.4169	Cd07642	BAR_ASAP2	-	Cl12013
Non-specific	223738	626	767	9.03716e-07	50.5931	COG0666	ANKYR	C	Cl34000
Non-specific	270093	270	366	1.38438e-06	47.0058	Cd13274	PH_DGK_type2	-	Cl17171
Non-specific	165206	637	753	1.49644e-06	51.1452	PHA02875	PHA02875	NC	Cl31516
Superfamily	165206	637	753	1.49644e-06	51.1452	Cl31516	PHA02875 superfamily	NC	-
Non-specific	153325	70	220	3.84819e-06	48.5165	Cd07641	BAR_ASAP1	N	Cl12013
Non-specific	350090	405	512	4.86899e-06	46.1351	Cd17903	ArfGap_AGFG2	-	Cl28907
Non-specific	241447	269	357	6.6052e-06	45.0117	Cd13293	PH_CpORP2-like	-	Cl17171
Non-specific	316185	670	721	1.33696e-05	43.0401	Pfam13637	Ank_4	-	Cl37869
Superfamily	316185	670	721	1.33696e-05	43.0401	Cl37869	Ank_4 superfamily	-	-
Non-specific	270090	267	362	1.72997e-05	44.2677	Cd13271	PH2_TAPP1_2	-	Cl17171
Non-specific	241522	267	353	2.16917e-05	44.6412	Cd13371	PH_GAP1_mammal-like	-	Cl17171
Non-specific	270099	262	365	2.25111e-05	44.6211	Cd13281	PH_PLEKHD1	-	Cl17171
Non-specific	222984	625	753	2.39448e-05	47.3522	PHA03100	PHA03100	C	Cl33710
Non-specific	165207	681	759	2.63691e-05	47.7506	PHA02876	PHA02876	NC	Cl31517
Superfamily	165207	681	759	2.63691e-05	47.7506	Cl31517	PHA02876 superfamily	NC	-
Non-specific	270101	269	365	3.01899e-05	43.1355	Cd13284	PH_OSBP_ORP4	-	Cl17171
Non-specific	269965	268	366	3.94128e-05	43.2172	Cd01264	PH_MELT_VEPH1	-	Cl17171
Non-specific	270071	262	366	4.97178e-05	42.7344	Cd13251	PH_ASAP	-	Cl17171
Non-specific	241448	271	358	6.78209e-05	42.4818	Cd13294	PH_ORP_plant	-	Cl17171
Non-specific	270080	266	357	7.6773e-05	42.3316	Cd13260	PH_RASA1	-	Cl17171
Non-specific	333774	670	698	8.5783e-05	39.9448	Pfam00023	Ank	-	Cl02529
Superfamily	351788	670	698	8.5783e-05	39.9448	Cl02529	Ank superfamily	-	-
Non-specific	269944	269	361	0.000122466	42.6005	Cd01238	PH_Btk	C	Cl17171
Non-specific	269966	271	358	0.000127652	41.5391	Cd01265	PH_TBC1D2A	-	Cl17171
Non-specific	223738	637	729	0.000192673	43.6595	COG0666	ANKYR	N	Cl34000
Non-specific	165205	637	753	0.000213004	44.184	PHA02874	PHA02874	NC	Cl31515
Superfamily	165205	637	753	0.000213004	44.184	Cl31515	PHA02874 superfamily	NC	-
Non-specific	316380	653	708	0.000242895	39.2755	Pfam13857	Ank_5	-	Cl37872
Superfamily	316380	653	708	0.000242895	39.2755	Cl37872	Ank_5 superfamily	-	-
Non-specific	215625	657	753	0.000354858	44.0886	PLN03192	PLN03192	NC	Cl33658
Superfamily	215625	657	753	0.000354858	44.0886	Cl33658	PLN03192 superfamily	NC	-
Non-specific	270074	302	357	0.00041142	39.7065	Cd13254	PH2_ARAP	N	Cl17171
Non-specific	165205	653	753	0.000488521	43.0284	PHA02874	PHA02874	NC	Cl31515
Non-specific	222939	637	767	0.000521994	43.3302	PHA02878	PHA02878	NC	Cl33699
Superfamily	222939	637	767	0.000521994	43.3302	Cl33699	PHA02878 superfamily	NC	-
Non-specific	153293	35	183	0.000531097	41.8865	Cd07609	BAR_SIP3_fungi	C	Cl12013
Non-specific	270094	271	363	0.000581137	39.6237	Cd13275	PH_M-RIP	-	Cl17171
Non-specific	269927	268	353	0.00101425	39.5478	Cd01218	PH_Phafin2-like	N	Cl17171
Non-specific	165206	617	753	0.00187374	41.13	PHA02875	PHA02875	C	Cl31516
Non-specific	270111	265	360	0.00196074	38.3769	Cd13299	PH2_PH_fungal	-	Cl17171
Non-specific	269947	267	359	0.0022575	37.9971	Cd01241	PH_PKB	-	Cl17171
Non-specific	270058	269	355	0.0022918	38.0112	Cd13238	PH2_FGD4_insect-like	-	Cl17171
Non-specific	269950	270	355	0.00244144	38.0381	Cd01244	PH_GAP1-like	-	Cl17171
Non-specific	222980	653	783	0.00251759	40.7783	PHA03095	PHA03095	NC	Cl33707
Non-specific	165207	653	746	0.00273342	41.2023	PHA02876	PHA02876	NC	Cl31517
Non-specific	241446	269	366	0.00392881	37.2875	Cd13292	PH_Osh1p_Osh2p_yeast	-	Cl17171
Non-specific	333774	700	732	0.00416981	35.3224	Pfam00023	Ank	-	Cl02529
Non-specific	214787	6	219	0.00441374	39.2896	Smart00721	BAR	-	Cl12013
Non-specific	270087	266	367	0.00549651	37.6916	Cd13267	PH_DOCK-D	-	Cl17171
Specific	316185	637	688	0.00608997	35.3361	Pfam13637	Ank_4	-	Cl37869
Superfamily	316185	637	688	0.00608997	35.3361	Cl37869	Ank_4 superfamily	-	-
Non-specific	165207	641	753	0.00761748	39.6615	PHA02876	PHA02876	NC	Cl31517
Non-specific	270081	269	377	0.00873894	37.0192	Cd13261	PH_RasGRF1_2	-	Cl17171

PROSITE
PROSITE ID	Family
PS50297	ANK_REP_REGION
PS50088	ANK_REPEAT
PS50115	ARFGAP
PS50003	PH_DOMAIN

Gene3D
CATH SUPERFAMILY CODE	Start-End	E-value	Domain
1.20.1270.60	1-255	2.9e-83	Arfaptin homology (AH) domain/BAR domain
2.30.29.30	261-376	3.1e-32	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
3.30.40.160	400-517	5.7e-44	Arf GTPase activating protein
1.25.40.20	596-755	1.2e-51	Ankyrin repeat-containing domain