DrLLPS - Data resource of LLPS

Disorder▼
- IUPred2A
Domain▼
PTM▼
Variation▼
- VarCards
Mutation▼
Interaction▼
Disease▼
- OMIM
- ActiveDriverDB
Drug▼
Physicochemical▼
- Compute pI/Mw
- AAindex
Function▼
- CellMarker
- RaftProt
Proteomics▼
- THPA
- HPM
Structure▼
Localization▼
- COMPARTMENTS
Expression▼
Element▼
Methylation▼

ICGC
CGAP
IntOGen
BioMuta

ICGC
Mutation	Project	AA Mutation	CDS Mutation	Chromosome	Start	End	Type	Consequence
MU63811858	BRCA-EU	P387S	1159 C>T	17	29622191	29622191	Single base substitution	Missense_variant
MU66868489	BRCA-EU	Y267*	801 T>A	17	29622549	29622549	Single base substitution	Stop_gained
MU80617386	BRCA-FR	Y64S	191 A>C	17	29623159	29623159	Single base substitution	Missense_variant
MU1995657	BRCA-UK	G272E	815 G>A	17	29622535	29622535	Single base substitution	Missense_variant
MU95454705	BTCA-SG	T309K	926 C>A	17	29622424	29622424	Single base substitution	Missense_variant
MU29141013	CESC-US	L10V	28 C>G	17	29623322	29623322	Single base substitution	Missense_variant
MU29140995	CESC-US	L429F	1285 C>T	17	29622065	29622065	Single base substitution	Missense_variant
MU50740	CLLE-ES	M104K	311 T>A	17	29623039	29623039	Single base substitution	Missense_variant
MU91780595	COAD-US	N88S	263 A>G	17	29623087	29623087	Single base substitution	Missense_variant
MU91780569	COAD-US	K202T	605 A>C	17	29622745	29622745	Single base substitution	Missense_variant
MU48432327	COCA-CN	L158P	473 T>C	17	29622877	29622877	Single base substitution	Missense_variant
MU46072596	COCA-CN	N224S	671 A>G	17	29622679	29622679	Single base substitution	Missense_variant
MU46828273	COCA-CN	S178Y	533 C>A	17	29622817	29622817	Single base substitution	Missense_variant
MU46828254	COCA-CN	F428S	1283 T>C	17	29622067	29622067	Single base substitution	Missense_variant
MU97047675	ESAD-UK	L80V	238 C>G	17	29623112	29623112	Single base substitution	Missense_variant
MU97049411	ESAD-UK	S374F	1121 C>T	17	29622229	29622229	Single base substitution	Missense_variant
MU97047325	ESAD-UK	L429L	1287 C>G	17	29622063	29622063	Single base substitution	Synonymous_variant
MU92706014	ESAD-UK	L402L	1204 T>C	17	29622146	29622146	Single base substitution	Synonymous_variant
MU68312155	ESAD-UK	N401H	1201 A>C	17	29622149	29622149	Single base substitution	Missense_variant
MU91709710	GBM-US	R99R	297 G>A	17	29623053	29623053	Single base substitution	Synonymous_variant
MU28787998	LAML-KR	T75T	225 C>T	17	29623125	29623125	Single base substitution	Synonymous_variant
MU29904774	LICA-FR	N265S	794 A>G	17	29622556	29622556	Single base substitution	Missense_variant
MU29904802	LICA-FR	L70P	209 T>C	17	29623141	29623141	Single base substitution	Missense_variant
MU29904824	LICA-FR	I14N	41 T>A	17	29623309	29623309	Single base substitution	Missense_variant
MU30135935	LICA-FR	Y64Y	192 T>C	17	29623158	29623158	Single base substitution	Synonymous_variant
MU29530157	LIHC-US	S345T	1033 T>A	17	29622317	29622317	Single base substitution	Missense_variant
MU3300597	LIRI-JP	H96H	288 C>T	17	29623062	29623062	Single base substitution	Synonymous_variant
MU926318	LIRI-JP	E392K	1174 G>A	17	29622176	29622176	Single base substitution	Missense_variant
MU80586049	READ-US	F215V	643 T>G	17	29622707	29622707	Single base substitution	Missense_variant
MU4396044	SKCM-US	A330T	988 G>A	17	29622362	29622362	Single base substitution	Missense_variant
MU4402890	SKCM-US	D208E	624 C>A	17	29622726	29622726	Single base substitution	Missense_variant
MU4463234	SKCM-US	V434A	1301 T>C	17	29622049	29622049	Single base substitution	Missense_variant
MU5332581	STAD-US	T399T	1197 C>A	17	29622153	29622153	Single base substitution	Synonymous_variant
MU1838260	UCEC-US	F67L	201 T>G	17	29623149	29623149	Single base substitution	Missense_variant
MU1893343	UCEC-US	D321Y	961 G>T	17	29622389	29622389	Single base substitution	Missense_variant
MU1891035	UCEC-US	A426T	1276 G>A	17	29622074	29622074	Single base substitution	Missense_variant
MU1980457	UCEC-US	R308*	922 C>T	17	29622428	29622428	Single base substitution	Stop_gained
MU1863303	UCEC-US	L148L	444 C>T	17	29622906	29622906	Single base substitution	Synonymous_variant

CGAP
UniGene	Cytoband	OMIM	SNP
Hs.113874	17q11.2	164345

IntOGen
Cancer	Mutation AA	cDNA	Chr	Position	Consequence
BRCA	p.G272E	c.815 G>A	17	29622535	Missense
CLL	p.C26R	c.76 T>C	17	29623274	Missense
CLL	p.M104K	c.311 T>A	17	29623039	Missense
CM	p.S319C	c.955 A>T	17	29622395	Missense
OV	p.P253L	c.758 C>T	17	29622592	Missense
UCEC	p.F67L	c.201 T>G	17	29623149	Missense
UCEC	p.A426T	c.1276 G>A	17	29622074	Missense

BioMuta
Position	Ref	Var	Position (AA)	Ref (AA)	Var (AA)	Cancer Type	Function	References
426	A	T	1276	G	A	DOID:363 / Uterine cancer [Uteca]	Loss\|+1 from N-linked Glycosylation	-
67	F	L	201	T	G	DOID:363 / Uterine cancer [Uteca]	-	-
186	T	A	556	A	G	DOID:219 / Colon cancer [Colca]	Gain\|Phosphorylation	-
412	K	N	1236	G	T	DOID:219 / Colon cancer [Colca]	-	-
253	P	Q	758	C	A	DOID:219 / Colon cancer [Colca]	Gain\|Phosphorylation	-
395	Q	STOP	1183	C	T	DOID:10283 / Prostate cancer [PCa]	-	22610119
104	M	K	311	T	A	DOID:2531 / Hematologic cancer [Hemca]	Gain\|Phosphorylation	22158541
321	D	Y	961	G	T	DOID:363 / Uterine cancer [Uteca]	-	-
285	T	I	854	C	T	DOID:363 / Uterine cancer [Uteca]	-	-
26	C	R	76	T	C	DOID:2531 / Hematologic cancer [Hemca]	-	23415222
302	K	T	905	A	C	DOID:219 / Colon cancer [Colca]	-	22895193
392	E	K	1174	G	A	DOID:3571 / Liver cancer [Livca]	Gain\|Glycosylation	-
253	P	L	758	C	T	DOID:2394 / Ovarian cancer [OVCA]	-	21720365
162	P	T	484	C	A	DOID:1324 / Lung cancer [Lunca]	Gain\|Phosphorylation	-
177	N	T	530	A	C	DOID:219 / Colon cancer [Colca]	Loss\|+1 from N-linked Glycosylation	23856246
426	A	T	1276	G	A	DOID:363 / Uterine cancer [Uteca]	Loss\|+1 from N-linked Glycosylation	-
67	F	L	201	T	G	DOID:363 / Uterine cancer [Uteca]	-	-
253	P	L	758	C	T	DOID:2394 / Ovarian cancer [OVCA]	-	-
26	C	R	76	T	C	DOID:2531 / Hematologic cancer [Hemca]	-	-
104	M	K	311	T	A	DOID:2531 / Hematologic cancer [Hemca]	Gain\|Phosphorylation	-
272	G	E	815	G	A	DOID:1612 / Breast cancer [BRCA]	-	-
434	V	A	1301	T	C	DOID:4159 / Skin cancer [Skica]	-	-
392	E	K	1174	G	A	DOID:3571 / Liver cancer [Livca]	Gain\|Glycosylation	-
330	A	T	988	G	A	DOID:4159 / Skin cancer [Skica]	Gain\|Phosphorylation	-
272	G	E	815	G	A	DOID:1612 / Breast cancer [BRCA]	-	-
208	D	E	624	C	A	DOID:4159 / Skin cancer [Skica]	-	-
104	M	K	311	T	A	DOID:2531 / Hematologic cancer [Hemca]	Gain\|Phosphorylation	-
308	R	STOP	922	C	T	DOID:363 / Uterine cancer [Uteca]	-	-
390	F	I	1168	T	A	DOID:2531 / Hematologic cancer [Hemca]	Loss\|+1 from N-linked Glycosylation	23297126
390	F	Y	1169	T	A	DOID:2531 / Hematologic cancer [Hemca]	Loss\|+1 from N-linked Glycosylation	23297126
390	F	L	1170	C	G	DOID:2531 / Hematologic cancer [Hemca]	Loss\|+1 from N-linked Glycosylation	23297126
67	F	L	201	T	G	DOID:363 / Uterine cancer [Uteca]	-	-
202	K	T	605	A	C	DOID:219 / Colon cancer [Colca]	Gain\|Glycosylation	-
285	T	I	854	C	T	DOID:363 / Uterine cancer [Uteca]	-	-
426	A	T	1276	G	A	DOID:363 / Uterine cancer [Uteca]	Loss\|+1 from N-linked Glycosylation	-
308	R	STOP	922	C	T	DOID:363 / Uterine cancer [Uteca]	-	-
321	D	Y	961	G	T	DOID:363 / Uterine cancer [Uteca]	-	-
208	D	E	624	C	A	DOID:4159 / Skin cancer [Skica]	-	-
434	V	A	1301	T	C	DOID:4159 / Skin cancer [Skica]	-	-
330	A	T	988	G	A	DOID:4159 / Skin cancer [Skica]	Gain\|Phosphorylation	-
179	L	F	537	G	T	DOID:1793 / Pancreatic cancer [PACA]	Gain\|Glycosylation	-
346	H	L	1037	A	T	DOID:2394 / Ovarian cancer [OVCA]	-	-
345	S	T	1033	T	A	DOID:3571 / Liver cancer [Livca]	-	-
272	G	E	815	G	A	DOID:1612 / Breast cancer [BRCA]	-	22722201
390	F	L	1170	C	A	DOID:11934 / Head and neck cancer [H/NC]	Loss\|+1 from N-linked Glycosylation	-
10	L	V	28	C	G	DOID:4362 / Cervical cancer [Cerca]	-	-
429	L	F	1285	C	T	DOID:4362 / Cervical cancer [Cerca]	Gain\|Glycosylation	-
318	L	V	952	C	G	DOID:3953 / Adrenal gland cancer [Adrgc]	-	-