※ Regulator introduction

    The LLPS of scaffold proteins and the stability of MLOs can be modulated by PTMs and other proteins (1-4). For example, arginine methylation of FUS by PRMT1 or PRMT8 reduces the LLPS of FUS, and both PRMTs were classified as PTM regulators. Also, Buchan et al. conducted a microscopy-based genetic screen of >4000 gene deletions in Saccharomyces cerevisiae, and identified 125 genes to be involved in regulating the stability and formation of P-bodies and/or stress granules (5). None of these proteins have been characterized to undergo LLPS, and here we classified all the 125 proteins as MLO regulators.

References
1. Vernon, R.M. and Forman-Kay, J.D. (2019) First-generation predictors of biological protein phase separation. Current opinion in structural biology 58, 88-96. PMID: 31252218
2. Wang, Z. and Zhang, H. (2019) Phase Separation, Transition, and Autophagic Degradation of Proteins in Development and Pathogenesis. Trends in cell biology, 29, 417-427. PMID: 30826216
3. Alberti, S., Gladfelter, A. and Mittag, T. (2019) Considerations and challenges in studying liquid-liquid phase separation and biomolecular condensates. Cell, 176, 419-434. PMID: 30682370
4. Bergeron-Sandoval, L.P., Safaee, N. and Michnick, S.W. (2016) Mechanisms and Consequences of Macromolecular Phase Separation. Cell, 165, 1067-1079. PMID: 27203111
5. Buchan, J.R., Kolaitis, R.M., Taylor, J.P. and Parker, R. (2013) Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function. Cell, 176, 419-434. PMID: 23791177

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Sol-0004	Solyc02g062620.3
2		LLPS-Sol-0009	Solyc04g074300.3
3		LLPS-Sol-0013	Solyc08g077700.3
4		LLPS-Sol-0016	Solyc02g070510.3
5		LLPS-Sol-0017	Solyc09g065330.3
6		LLPS-Sol-0019	Solyc02g082190.3
7		LLPS-Sol-0026	Solyc09g007940.3
8		LLPS-Sol-0033	Solyc01g028930.3
9		LLPS-Sol-0035	Solyc09g010500.3
10		LLPS-Sol-0038	Solyc02g081680.3
11		LLPS-Sol-0045	Solyc01g094540.3
12		LLPS-Sol-0047	Solyc03g007430.3
13		LLPS-Sol-0048	Solyc04g064700.3
14		LLPS-Sol-0059	Solyc05g053220.3
15		LLPS-Sol-0061	Solyc01g100720.3
16		LLPS-Sol-0062	Solyc01g005960.3
17		LLPS-Sol-0064	Solyc10g006470.3
18		LLPS-Sol-0069	Solyc01g110530.3
19		LLPS-Sol-0072	Solyc02g079110.3
20		LLPS-Sol-0079	Solyc10g078860.2
21		LLPS-Sol-0096	Solyc07g017660.2
22		LLPS-Sol-0104	Solyc01g102370.3
23		LLPS-Sol-0114	Solyc02g078120.2
24		LLPS-Sol-0120	Solyc07g006790.3
25		LLPS-Sol-0127	Solyc02g021550.3
26		LLPS-Sol-0129	Solyc09g097830.3
27		LLPS-Sol-0141	Solyc02g068420.3
28		LLPS-Sol-0147	Solyc08g016420.3
29		LLPS-Sol-0149	Solyc01g097110.2
30		LLPS-Sol-0160	Solyc08g076660.3
31		LLPS-Sol-0164	Solyc08g061850.3
32		LLPS-Sol-0166	Solyc04g016380.3
33		LLPS-Sol-0173	Solyc07g054140.3
34		LLPS-Sol-0175	Solyc01g100650.3
35		LLPS-Sol-0185	Solyc03g119790.3
36		LLPS-Sol-0189	Solyc04g007560.3
37		LLPS-Sol-0195	Solyc07g049480.3
38		LLPS-Sol-0197	Solyc10g005530.3
39		LLPS-Sol-0199	Solyc03g063220.2
40		LLPS-Sol-0201	Solyc06g074720.3
41		LLPS-Sol-0206	Solyc01g088370.3
42		LLPS-Sol-0212	Solyc06g053385.1
43		LLPS-Sol-0215	Solyc03g082920.3
44		LLPS-Sol-0220	Solyc04g074490.3
45		LLPS-Sol-0239	Solyc10g081030.2
46		LLPS-Sol-0242	Solyc01g008270.3
47		LLPS-Sol-0253	Solyc03g051900.3
48		LLPS-Sol-0255	Solyc03g114690.3
49		LLPS-Sol-0260	Solyc07g065950.3
50		LLPS-Sol-0266	Solyc02g089280.3
51		LLPS-Sol-0268	Solyc12g095860.2
52		LLPS-Sol-0276	Solyc05g017893.1
53		LLPS-Sol-0283	Solyc03g118350.3
54		LLPS-Sol-0286	Solyc06g005670.3
55		LLPS-Sol-0287	Solyc01g088080.3
56		LLPS-Sol-0288	Solyc03g032070.3
57		LLPS-Sol-0291	Solyc12g099890.2
58		LLPS-Sol-0295	Solyc06g071470.3
59		LLPS-Sol-0302	Solyc02g069340.3
60		LLPS-Sol-0303	Solyc09g048990.3
61		LLPS-Sol-0305	Solyc11g071910.2
62		LLPS-Sol-0312	Solyc05g054810.3
63		LLPS-Sol-0316	Solyc12g099910.2
64		LLPS-Sol-0317	Solyc01g110130.3
65		LLPS-Sol-0323	Solyc11g009090.2
66		LLPS-Sol-0326	Solyc03g062650.3
67		LLPS-Sol-0327	Solyc02g038750.3
68		LLPS-Sol-0331	Solyc03g123730.3
69		LLPS-Sol-0347	Solyc09g059310.3
70		LLPS-Sol-0349	Solyc03g113780.3
71		LLPS-Sol-0350	Solyc06g053210.3
72		LLPS-Sol-0353	Solyc12g008760.2
73		LLPS-Sol-0357	Solyc10g080180.2
74		LLPS-Sol-0366	Solyc08g078070.3
75		LLPS-Sol-0368	Solyc03g019780.3
76		LLPS-Sol-0372	Solyc02g066830.3
77		LLPS-Sol-0375	Solyc01g079507.1
78		LLPS-Sol-0377	Solyc01g068240.3
79		LLPS-Sol-0412	Solyc11g039830.2
80		LLPS-Sol-0413	Solyc03g112820.3
81		LLPS-Sol-0419	Solyc06g074980.3
82		LLPS-Sol-0420	Solyc09g061430.3
83		LLPS-Sol-0421	Solyc01g095710.3
84		LLPS-Sol-0424	Solyc00g007270.3
85		LLPS-Sol-0426	Solyc09g005760.3
86		LLPS-Sol-0428	Solyc02g091790.3
87		LLPS-Sol-0435	Solyc03g007100.3
88		LLPS-Sol-0452	Solyc09g066495.1
89		LLPS-Sol-0467	Solyc03g093260.3
90		LLPS-Sol-0491	Solyc12g015780.2
91		LLPS-Sol-0494	Solyc08g076335.1
92		LLPS-Sol-0514	Solyc12g095960.2
93		LLPS-Sol-0529	Solyc11g008670.2
94		LLPS-Sol-0530	Solyc06g060780.3	Q84V30
95		LLPS-Sol-0540	Solyc02g093390.3
96		LLPS-Sol-0543	Solyc03g122110.1
97		LLPS-Sol-0558	Solyc01g099300.3
98		LLPS-Sol-0561	Solyc07g005050.3
99		LLPS-Sol-0565	Solyc01g107870.3
100		LLPS-Sol-0574	Solyc03g098280.3
101		LLPS-Sol-0579	Solyc09g007540.3
102		LLPS-Sol-0590	Solyc10g039190.2
103		LLPS-Sol-0603	Solyc03g118010.3
104		LLPS-Sol-0604	Solyc10g047000.2
105		LLPS-Sol-0607	Solyc01g103800.3
106		LLPS-Sol-0612	Solyc11g005110.2
107		LLPS-Sol-0616	Solyc05g056160.3
108		LLPS-Sol-0621	Solyc07g008880.3
109		LLPS-Sol-0630	Solyc02g070310.3
110		LLPS-Sol-0640	Solyc09g091520.2
111		LLPS-Sol-0644	Solyc12g008750.2
112		LLPS-Sol-0648	Solyc11g069150.2
113		LLPS-Sol-0658	Solyc01g103720.3
114		LLPS-Sol-0666	Solyc06g034160.3
115		LLPS-Sol-0679	Solyc12g056110.2
116		LLPS-Sol-0686	Solyc04g079200.3
117		LLPS-Sol-0687	Solyc09g005640.3
118		LLPS-Sol-0693	Solyc06g071770.3
119		LLPS-Sol-0709	Solyc12g006010.2
120		LLPS-Sol-0710	Solyc01g068390.3
121		LLPS-Sol-0716	Solyc01g067830.3
122		LLPS-Sol-0724	Solyc01g094000.3
123		LLPS-Sol-0727	Solyc07g049590.3
124		LLPS-Sol-0732	Solyc01g111450.3
125		LLPS-Sol-0733	Solyc01g094350.3
126		LLPS-Sol-0742	Solyc04g064560.3
127		LLPS-Sol-0751	Solyc04g010290.3
128		LLPS-Sol-0759	Solyc11g062270.2
129		LLPS-Sol-0764	Solyc11g020810.2
130		LLPS-Sol-0774	Solyc12g006550.2
131		LLPS-Sol-0775	Solyc06g071200.3
132		LLPS-Sol-0781	Solyc03g114370.3
133		LLPS-Sol-0783	Solyc03g119040.3
134		LLPS-Sol-0793	Solyc06g073330.3
135		LLPS-Sol-0799	Solyc10g005560.3
136		LLPS-Sol-0814	Solyc12g062870.2
137		LLPS-Sol-0816	Solyc02g067970.3
138		LLPS-Sol-0832	Solyc06g075590.3
139		LLPS-Sol-0837	Solyc10g008180.2
140		LLPS-Sol-0841	Solyc09g009040.3
141		LLPS-Sol-0850	Solyc02g081700.1
142		LLPS-Sol-0856	Solyc12g044730.2
143		LLPS-Sol-0858	Solyc08g007520.3
144		LLPS-Sol-0861	Solyc09g005330.3
145		LLPS-Sol-0864	Solyc11g017070.2
146		LLPS-Sol-0875	Solyc03g116730.3
147		LLPS-Sol-0880	Solyc03g117970.3
148		LLPS-Sol-0887	Solyc01g099900.3
149		LLPS-Sol-0891	Solyc03g093680.3	K4BIP4
150		LLPS-Sol-0892	Solyc08g006700.3
151		LLPS-Sol-0909	Solyc04g077920.3
152		LLPS-Sol-0915	Solyc12g056940.2
153		LLPS-Sol-0927	Solyc11g069370.2
154		LLPS-Sol-0930	Solyc11g007940.2
155		LLPS-Sol-0934	Solyc01g100430.3
156		LLPS-Sol-0956	Solyc05g054630.3
157		LLPS-Sol-0961	Solyc01g111710.3
158		LLPS-Sol-0963	Solyc03g115810.3
159		LLPS-Sol-0969	Solyc09g064660.3
160		LLPS-Sol-0970	Solyc02g093900.3
161		LLPS-Sol-0973	Solyc06g074210.3
162		LLPS-Sol-0975	Solyc01g095410.3
163		LLPS-Sol-0981	Solyc01g106770.3
164		LLPS-Sol-0993	Solyc09g010460.3
165		LLPS-Sol-1044	Solyc06g082650.3
166		LLPS-Sol-1045	Solyc12g044640.2
167		LLPS-Sol-1047	Solyc02g082180.3
168		LLPS-Sol-1072	Solyc01g109960.3
169		LLPS-Sol-1073	Solyc01g044360.3
170		LLPS-Sol-1077	Solyc03g097290.3
171		LLPS-Sol-1082	Solyc01g096800.3
172		LLPS-Sol-1092	Solyc03g117030.2
173		LLPS-Sol-1096	Solyc04g081280.3
174		LLPS-Sol-1102	Solyc10g078450.2
175		LLPS-Sol-1108	Solyc10g054560.2	O24011
176		LLPS-Sol-1120	Solyc08g062800.3
177		LLPS-Sol-1123	Solyc06g069280.3
178		LLPS-Sol-1133	Solyc09g010190.3
179		LLPS-Sol-1136	Solyc03g111630.3
180		LLPS-Sol-1161	Solyc07g007690.3
181		LLPS-Sol-1166	Solyc10g080560.2
182		LLPS-Sol-1167	Solyc09g082320.3
183		LLPS-Sol-1168	Solyc07g065550.3
184		LLPS-Sol-1171	Solyc06g073120.3
185		LLPS-Sol-1172	Solyc10g055670.2
186		LLPS-Sol-1181	Solyc05g050680.3
187		LLPS-Sol-1188	Solyc06g050770.3
188		LLPS-Sol-1191	Solyc03g095840.3
189		LLPS-Sol-1198	Solyc06g071870.3
190		LLPS-Sol-1225	Solyc01g097640.3
191		LLPS-Sol-1237	Solyc05g009600.3
192		LLPS-Sol-1241	Solyc04g057880.3
193		LLPS-Sol-1246	Solyc07g016200.3
194		LLPS-Sol-1253	Solyc01g112150.3
195		LLPS-Sol-1262	Solyc04g063280.3
196		LLPS-Sol-1268	Solyc09g091280.3
197		LLPS-Sol-1273	Solyc01g094480.3
198		LLPS-Sol-1284	Solyc12g010520.2
199		LLPS-Sol-1297	Solyc06g053590.3
200		LLPS-Sol-1299	Solyc01g099760.3
201		LLPS-Sol-1301	Solyc05g009980.3
202		LLPS-Sol-1303	Solyc01g087095.1
203		LLPS-Sol-1315	Solyc10g081170.2
204		LLPS-Sol-1322	Solyc10g079880.2
205		LLPS-Sol-1325	Solyc11g071660.1
206		LLPS-Sol-1327	Solyc05g013820.3
207		LLPS-Sol-1331	Solyc01g095040.3
208		LLPS-Sol-1347	Solyc07g007210.3
209		LLPS-Sol-1366	Solyc01g102970.3
210		LLPS-Sol-1369	Solyc08g061000.3
211		LLPS-Sol-1376	Solyc06g005865.1
212		LLPS-Sol-1383	Solyc03g120010.3
213		LLPS-Sol-1385	Solyc06g053800.2
214		LLPS-Sol-1387	Solyc01g111780.3
215		LLPS-Sol-1398	Solyc04g012060.3
216		LLPS-Sol-1413	Solyc06g063000.3
217		LLPS-Sol-1414	Solyc01g096580.3
218		LLPS-Sol-1423	Solyc01g005430.3
219		LLPS-Sol-1441	Solyc02g085420.3
220		LLPS-Sol-1442	Solyc04g074910.3
221		LLPS-Sol-1449	Solyc01g098870.3
222		LLPS-Sol-1460	Solyc06g061120.3
223		LLPS-Sol-1471	Solyc11g040120.2
224		LLPS-Sol-1484	Solyc02g089890.3
225		LLPS-Sol-1487	Solyc07g008760.3
226		LLPS-Sol-1501	Solyc04g063290.3
227		LLPS-Sol-1502	Solyc07g056540.3
228		LLPS-Sol-1505	Solyc09g010330.3
229		LLPS-Sol-1511	Solyc01g010540.3
230		LLPS-Sol-1514	Solyc11g072880.2
231		LLPS-Sol-1518	Solyc11g005600.2
232		LLPS-Sol-1521	Solyc05g008480.3
233		LLPS-Sol-1545	Solyc11g013520.2
234		LLPS-Sol-1571	Solyc07g065900.3
235		LLPS-Sol-1577	Solyc01g102570.3
236		LLPS-Sol-1585	Solyc11g066480.2
237		LLPS-Sol-1588	Solyc08g074790.3
238		LLPS-Sol-1596	Solyc08g081280.3
239		LLPS-Sol-1599	Solyc01g106020.3
240		LLPS-Sol-1608	Solyc06g071530.3
241		LLPS-Sol-1623	Solyc10g081020.2
242		LLPS-Sol-1625	Solyc01g066610.3
243		LLPS-Sol-1630	Solyc06g007870.3
244		LLPS-Sol-1636	Solyc09g005100.3
245		LLPS-Sol-1637	Solyc06g076460.3
246		LLPS-Sol-1650	Solyc03g111380.3
247		LLPS-Sol-1659	Solyc01g110410.3
248		LLPS-Sol-1673	Solyc05g055160.3
249		LLPS-Sol-1676	Solyc11g005800.2
250		LLPS-Sol-1678	Solyc03g044140.3
251		LLPS-Sol-1680	Solyc08g005970.3
252		LLPS-Sol-1684	Solyc11g013440.2
253		LLPS-Sol-1693	Solyc05g005610.3
254		LLPS-Sol-1694	Solyc11g068870.2
255		LLPS-Sol-1725	Solyc03g118020.3
256		LLPS-Sol-1748	Solyc09g090200.3
257		LLPS-Sol-1755	Solyc08g074550.3
258		LLPS-Sol-1769	Solyc07g065930.3
259		LLPS-Sol-1771	Solyc02g082460.3
260		LLPS-Sol-1778	Solyc10g038120.2
261		LLPS-Sol-1787	Solyc04g076390.3
262		LLPS-Sol-1797	Solyc03g121140.3
263		LLPS-Sol-1798	Solyc09g014320.3
264		LLPS-Sol-1802	Solyc02g081810.3
265		LLPS-Sol-1811	Solyc04g082320.3
266		LLPS-Sol-1812	Solyc01g090780.3
267		LLPS-Sol-1824	Solyc01g104920.3
268		LLPS-Sol-1834	Solyc12g021190.2
269		LLPS-Sol-1839	Solyc12g049570.2
270		LLPS-Sol-1852	Solyc03g115230.3
271		LLPS-Sol-1860	Solyc10g078950.2
272		LLPS-Sol-1861	Solyc07g052175.1
273		LLPS-Sol-1874	Solyc06g062980.3
274		LLPS-Sol-1876	Solyc03g115470.3
275		LLPS-Sol-1893	Solyc11g044965.1
276		LLPS-Sol-1906	Solyc03g005740.2
277		LLPS-Sol-1907	Solyc10g045390.2
278		LLPS-Sol-1911	Solyc11g068930.2
279		LLPS-Sol-1921	Solyc01g091500.3
280		LLPS-Sol-1927	Solyc07g055695.1
281		LLPS-Sol-1930	Solyc02g094160.1
282		LLPS-Sol-1934	Solyc06g054080.3
283		LLPS-Sol-1936	Solyc06g051270.3
284		LLPS-Sol-1937	Solyc04g009410.3
285		LLPS-Sol-1956	Solyc05g015630.3
286		LLPS-Sol-1962	Solyc06g065590.3
287		LLPS-Sol-1966	Solyc02g093830.3
288		LLPS-Sol-1982	Solyc06g063330.3
289		LLPS-Sol-2000	Solyc08g082200.3
290		LLPS-Sol-2004	Solyc11g007170.2
291		LLPS-Sol-2007	Solyc04g078620.3
292		LLPS-Sol-2008	Solyc12g089030.2
293		LLPS-Sol-2032	Solyc01g098180.3
294		LLPS-Sol-2037	Solyc08g062915.1
295		LLPS-Sol-2041	Solyc08g080170.3
296		LLPS-Sol-2046	Solyc01g087120.3
297		LLPS-Sol-2048	Solyc06g008330.2
298		LLPS-Sol-2066	Solyc09g082670.3
299		LLPS-Sol-2081	Solyc01g099830.3
300		LLPS-Sol-2082	Solyc03g025540.3
301		LLPS-Sol-2097	Solyc03g111730.3
302		LLPS-Sol-2112	Solyc03g120780.3
303		LLPS-Sol-2117	Solyc05g013790.3
304		LLPS-Sol-2146	Solyc04g080590.3
305		LLPS-Sol-2164	Solyc01g066590.3
306		LLPS-Sol-2184	Solyc06g082630.3
307		LLPS-Sol-2198	Solyc07g032080.3
308		LLPS-Sol-2200	Solyc12g098910.2
309		LLPS-Sol-2221	Solyc09g097880.3
310		LLPS-Sol-2224	Solyc04g008610.3
311		LLPS-Sol-2227	Solyc02g091110.3
312		LLPS-Sol-2265	Solyc02g069790.3
313		LLPS-Sol-2273	Solyc01g112350.3
314		LLPS-Sol-2279	Solyc08g068810.3
315		LLPS-Sol-2283	Solyc08g007360.3
316		LLPS-Sol-2288	Solyc03g115050.3
317		LLPS-Sol-2293	Solyc12g015660.2
318		LLPS-Sol-2307	Solyc01g111870.2
319		LLPS-Sol-2317	Solyc11g020890.2
320		LLPS-Sol-2332	Solyc02g061650.2
321		LLPS-Sol-2366	Solyc07g005090.3
322		LLPS-Sol-2370	Solyc06g053460.2
323		LLPS-Sol-2387	Solyc06g065170.3
324		LLPS-Sol-2414	Solyc06g076860.3
325		LLPS-Sol-2431	Solyc05g006590.3
326		LLPS-Sol-2453	Solyc03g120670.3
327		LLPS-Sol-2468	Solyc12g088680.2
328		LLPS-Sol-2484	Solyc03g118620.3
329		LLPS-Sol-2485	Solyc05g007755.1
330		LLPS-Sol-2494	Solyc12g088810.2
331		LLPS-Sol-2501	Solyc06g067880.3
332		LLPS-Sol-2518	Solyc02g084360.3
333		LLPS-Sol-2523	Solyc06g082220.3
334		LLPS-Sol-1367	Solyc07g064680.3	F1JYZ5	100736468
335		LLPS-Sol-0447	Solyc06g071210.3	Q56R02	101246352
336		LLPS-Sol-0711	Solyc11g065670.1	K4DAA0	101247691
337		LLPS-Sol-0474	Solyc02g021400.2	K4B4Z0	101248825
338		LLPS-Sol-1204	Solyc10g084310.2	K4D3L7	101252449
339		LLPS-Sol-2057	Solyc12g099820.1	K4DI03	101254464
340		LLPS-Sol-0551	Solyc12g056490.1	K4DFY0	101257937
341		LLPS-Sol-1345	Solyc02g086240.3	K4CG62	101259713
342		LLPS-Sol-2371	Solyc10g011740.3	K4CYF2	101260872
343		LLPS-Sol-0559	Solyc06g073790.3	K4C998	101266035
344		LLPS-Sol-0022	Solyc02g084920.3	K4BB06	101266585
345		LLPS-Sol-1999	Solyc03g115700.3	Q6XNM3	543870
346		LLPS-Sol-0851	Solyc10g006290.3	A0RZC9	CHRD
347		LLPS-Sol-2024	Solyc01g098610.3	E1U7P9	GSH2
348		LLPS-Sol-0008	Solyc12g019460.2	Q84MI6	MPK1
349		LLPS-Sol-1594	Solyc05g023800.3	P38546	RAN1
350		LLPS-Sol-0903	Solyc08g062660.3	Q94K24	RanBP1
351		LLPS-Sol-0890	Solyc06g065475.1	K4C7H6	RBM8
352		LLPS-Sol-0338	Solyc02g078260.3	Q42877	RPB2
353		LLPS-Sol-1890	Solyc10g083165.1	P49215	RPS17
354		LLPS-Sol-1067	Solyc05g053835.1	Q8RVB2	SPY
355		LLPS-Sol-1030	Solyc09g059970.3	Q9SMD1	sumo