Sarcophilus harrisii Stress granule
※ Stress granule introduction Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs) that form from mRNAs stalled in translation initiation, which form through interactions between mRNA-binding proteins that link together populations of mRNPs. Stress granules are a kind of conserved cytoplasmic mRNP and represent an active liquid wherein energy input maintains their dynamic state, its formation modulates the stress response and signaling pathways (1). Besides, stress granules facilitate the establishment of an antiviral state by limiting viral protein accumulation and regulating signalling cascades that affect virus replication and immune responses (2). Reference
1. McCormick, C., & Khaperskyy, D. A. (2017) Translation inhibition and stress granules in the antiviral immune response. Nat Rev Immunol, 17(10), 647-660. PMID: 28669985
2. Protter, D. S. W., & Parker, R. (2016) Principles and Properties of Stress Granules. Trends Cell Biol, 26(9), 668-679. PMID:27289443
There are 935 genes. Reviewed (0)
or Unreviewed (935) 
※ Stress granule introduction Stress granules are assemblies of untranslating messenger ribonucleoproteins (mRNPs) that form from mRNAs stalled in translation initiation, which form through interactions between mRNA-binding proteins that link together populations of mRNPs. Stress granules are a kind of conserved cytoplasmic mRNP and represent an active liquid wherein energy input maintains their dynamic state, its formation modulates the stress response and signaling pathways (1). Besides, stress granules facilitate the establishment of an antiviral state by limiting viral protein accumulation and regulating signalling cascades that affect virus replication and immune responses (2). Reference
1. McCormick, C., & Khaperskyy, D. A. (2017) Translation inhibition and stress granules in the antiviral immune response. Nat Rev Immunol, 17(10), 647-660. PMID: 28669985
2. Protter, D. S. W., & Parker, R. (2016) Principles and Properties of Stress Granules. Trends Cell Biol, 26(9), 668-679. PMID:27289443
There are 935 genes. Reviewed (0)
or Unreviewed (935)