Yarrowia lipolytica      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Yal-0117
YALI0_A00616g
Q6CI88
YALI0_A00616g
2
LLPS-Yal-0162
YALI0_B12210g
Q6CEX2
YALI0_B12210g
3
LLPS-Yal-0301
YALI0_E13684g
Q6C600
YALI0_E13684g
4
LLPS-Yal-0179
YALI0_E28371g
Q6C4A8
YALI0_E28371g
5
LLPS-Yal-0749
YALI0_F11693g
Q6C214
YALI0_F11693g
6
LLPS-Yal-0122
YALI0_F14179g
Q6C1R1
YALI0_F14179g
7
LLPS-Yal-0866
YALI0_F15763g
Q6C1J4
YALI0_F15763g
8
LLPS-Yal-0589
YALI0_F20526g
Q6C0Z5
YALI0_F20526g