Pan troglodytes      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 43 genes.  Reviewed (0 or Unreviewed (43

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pat-3249
ENSPTRG00000048111.1
A0A2I3RLS9
2
LLPS-Pat-0269
ENSPTRG00000013646.4
G2HFJ0
AURKA
3
LLPS-Pat-0838
ENSPTRG00000008731.5
H2QC74
AURKB
4
LLPS-Pat-2667
ENSPTRG00000009119.4
H2QCW3
CDC6
5
LLPS-Pat-2189
ENSPTRG00000052016.1
A0A2I3SX06
CHAMP1
6
LLPS-Pat-2792
ENSPTRG00000005903.4
K7A9E3
CKAP2
7
LLPS-Pat-1315
ENSPTRG00000003553.6
H2R5G4
CKAP5
8
LLPS-Pat-3851
ENSPTRG00000051534.1
A0A2I3SW32
CLTB
9
LLPS-Pat-0653
ENSPTRG00000020884.7
A0A2I3RSC3
DCTN3
10
LLPS-Pat-2145
ENSPTRG00000006371.5
H2Q8C6
DLGAP5
11
LLPS-Pat-1855
ENSPTRG00000020099.4
K6ZQM1
DPYSL2
12
LLPS-Pat-3411
ENSPTRG00000001914.6
H2Q103
DYRK3
13
LLPS-Pat-2702
ENSPTRG00000007462.5
H2QA35
FES
14
LLPS-Pat-4249
ENSPTRG00000001037.4
H2PZJ5
GPSM2
15
LLPS-Pat-0882
ENSPTRG00000015843.4
K7CSA4
HAUS3
16
LLPS-Pat-4544
ENSPTRG00000020800.6
K7C9H7
HAUS6
17
LLPS-Pat-2642
ENSPTRG00000013282.5
H2QK03
KAT14
18
LLPS-Pat-0938
ENSPTRG00000005753.6
H2Q7D4
KATNAL1
19
LLPS-Pat-0275
ENSPTRG00000002758.3
H2Q299
KIF11
20
LLPS-Pat-0352
ENSPTRG00000016401.6
H2QQ35
MAD2L1
21
LLPS-Pat-1174
ENSPTRG00000000149.5
H2PY08
MAD2L2
22
LLPS-Pat-2994
ENSPTRG00000020224.5
H2Q9G3
MAPK6
23
LLPS-Pat-0668
ENSPTRG00000013385.4
K7ARF5
MAPRE1
24
LLPS-Pat-3892
ENSPTRG00000051550.1
H2Q2D6
MARVELD1
25
LLPS-Pat-2300
ENSPTRG00000046874.1
A0A2I3SMJ4
MKNK1
26
LLPS-Pat-3378
ENSPTRG00000043871.1
K7BGD7
MSN
27
LLPS-Pat-3716
ENSPTRG00000000142.4
K7B4P2
MTOR
28
LLPS-Pat-2897
ENSPTRG00000020023.6
K7CHJ5
MTUS1
29
LLPS-Pat-1667
ENSPTRG00000002496.7
H2QRL5
NCOA4
30
LLPS-Pat-0175
ENSPTRG00000008744.6
K7CHH7
NDEL1
31
LLPS-Pat-3584
ENSPTRG00000002415.7
H2R1H3
PARD3
32
LLPS-Pat-1015
ENSPTRG00000007467.6
A0A2I3RHD3
PRC1
33
LLPS-Pat-4675
ENSPTRG00000008244.3
A0A2I3TQ05
RANBP10
34
LLPS-Pat-2182
ENSPTRG00000020135.6
H2QVZ7
RBPMS
35
LLPS-Pat-1587
ENSPTRG00000023481.5
H2R3C4
SEPT2
36
LLPS-Pat-2193
ENSPTRG00000002939.5
H2R1R2
SMC3
37
LLPS-Pat-3355
ENSPTRG00000047557.1
A0A2I3SGD7
SUN1
38
LLPS-Pat-2755
ENSPTRG00000023985.5
H2R4A1
SUN2
39
LLPS-Pat-1257
ENSPTRG00000014595.5
K7DHE7
TADA3
40
LLPS-Pat-1552
ENSPTRG00000049393.1
K7CX57
TMEM201
41
LLPS-Pat-2445
ENSPTRG00000001783.7
K7D5A9
TPR
42
LLPS-Pat-1890
ENSPTRG00000008690.5
H2QC42
ZBTB4
43
LLPS-Pat-4629
ENSPTRG00000008989.7
A0A2I3THL7
ZNF207