Komagataella pastoris      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Kop-0966
PAS_chr2-1_0331
C4R0C6
PAS_chr2-1_0331
2
LLPS-Kop-0412
PAS_chr2-2_0306
C4R276
PAS_chr2-2_0306
3
LLPS-Kop-1493
PAS_chr3_0599
C4R510
PAS_chr3_0599
4
LLPS-Kop-0240
PAS_chr4_0148
C4R6Z8
PAS_chr4_0148
5
LLPS-Kop-0280
PAS_chr4_0160
C4R710
PAS_chr4_0160
6
LLPS-Kop-0053
PAS_chr4_0282
C4R7E3
PAS_chr4_0282
7
LLPS-Kop-0163
PAS_chr4_0719
C4R8Q5
PAS_chr4_0719