Gaeumannomyces graminis      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gag-0078
GGTG_00125
J3NFT1
20340583
2
LLPS-Gag-0580
GGTG_01044
J3NIG3
20341502
3
LLPS-Gag-1383
GGTG_01556
J3NJX4
20342014
4
LLPS-Gag-0526
GGTG_02397
J3NM93
20342855
5
LLPS-Gag-1180
GGTG_03083
J3NP77
20343541
6
LLPS-Gag-0987
GGTG_03418
J3NQ61
20343876
7
LLPS-Gag-0509
GGTG_03903
J3NRJ9
20344361
8
LLPS-Gag-1003
GGTG_06851
J3P004
20347309
9
LLPS-Gag-0141
GGTG_09766
J3P8D2
20350224
10
LLPS-Gag-0128
GGTG_12764
J3PGY4
20353222
11
LLPS-Gag-0253
GGTG_13965
J3PKB5
20354423