Carlito syrichta      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cas-0341
ENSTSYG00000012319.2
2
LLPS-Cas-0658
ENSTSYG00000006298.2
3
LLPS-Cas-1651
ENSTSYG00000033527.1
4
LLPS-Cas-1694
ENSTSYG00000027636.1
5
LLPS-Cas-1789
ENSTSYG00000009201.2
6
LLPS-Cas-2182
ENSTSYG00000011405.2
7
LLPS-Cas-1922
ENSTSYG00000036090.1
A0A1U7TPV5
AURKA
8
LLPS-Cas-2249
ENSTSYG00000012554.2
A0A1U7TH01
AURKB
9
LLPS-Cas-3855
ENSTSYG00000007574.2
A0A1U7U579
CDC6
10
LLPS-Cas-3945
ENSTSYG00000002023.2
A0A1U7U9R1
DCTN3
11
LLPS-Cas-0094
ENSTSYG00000029688.1
A0A1U7T8D9
DPYSL2
12
LLPS-Cas-1285
ENSTSYG00000002133.2
A0A1U7SSB8
FES
13
LLPS-Cas-3511
ENSTSYG00000002594.2
A0A1U7UCK2
GPSM2
14
LLPS-Cas-3780
ENSTSYG00000001322.2
A0A1U7UER8
HAUS3
15
LLPS-Cas-3789
ENSTSYG00000009563.2
A0A1U7U8R3
HAUS6
16
LLPS-Cas-1202
ENSTSYG00000000383.2
A0A1U7TJG5
KAT14
17
LLPS-Cas-0964
ENSTSYG00000008120.2
A0A1U7TBU3
KATNA1
18
LLPS-Cas-1699
ENSTSYG00000010551.2
A0A1U7U7H8
KIF11
19
LLPS-Cas-2843
ENSTSYG00000010462.2
A0A1U7TQH1
LOC103264185
20
LLPS-Cas-0675
ENSTSYG00000012505.2
A0A1U7TIR3
MAD2L1
21
LLPS-Cas-0401
ENSTSYG00000031720.1
A0A1U7V0K0
MAD2L2
22
LLPS-Cas-1170
ENSTSYG00000000833.2
A0A1U7UKC2
MAPRE1
23
LLPS-Cas-3185
ENSTSYG00000007951.2
A0A1U7TNR8
MSN
24
LLPS-Cas-1725
ENSTSYG00000012607.2
A0A1U7U6S9
MTOR
25
LLPS-Cas-2967
ENSTSYG00000027281.1
A0A1U7TMN6
MTUS1
26
LLPS-Cas-3849
ENSTSYG00000008109.2
A0A1U7SZZ8
NCOA4
27
LLPS-Cas-2374
ENSTSYG00000009870.2
A0A1U7TVG7
PARD3
28
LLPS-Cas-3528
ENSTSYG00000012594.2
A0A1U7UF91
RANBP10
29
LLPS-Cas-2035
ENSTSYG00000003579.2
A0A1U7SR85
SEPT2
30
LLPS-Cas-0986
ENSTSYG00000005227.2
A0A1U7SZ70
SMC3
31
LLPS-Cas-0526
ENSTSYG00000002174.2
A0A1U7UNM7
SUN2
32
LLPS-Cas-2616
ENSTSYG00000034934.1
A0A1U7TVR8
ZBTB4
33
LLPS-Cas-1258
ENSTSYG00000003620.2
A0A1U7SJ20
ZNF207