Ashbya gossypii      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asg-0245
AGOS_AAL182W
Q75FB3
AGOS_AAL182W
2
LLPS-Asg-0640
AGOS_AAR024W
Q75EQ5
AGOS_AAR024W
3
LLPS-Asg-0363
AGOS_AAR137W
Q75EE4
AGOS_AAR137W
4
LLPS-Asg-0459
AGOS_ACL132C
Q75CQ1
AGOS_ACL132C
5
LLPS-Asg-0608
AGOS_ACR043W
Q75C73
AGOS_ACR043W
6
LLPS-Asg-0645
AGOS_AFR286W
Q753M6
AGOS_AFR286W
7
LLPS-Asg-1001
AGOS_AFR621C
Q752F5
AGOS_AFR621C
8
LLPS-Asg-1039
AGOS_ACR228C
Q8J1G4
KIP1