Taeniopygia guttata      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tag-0168
ENSTGUG00000001548.1
H0YTI6
2
LLPS-Tag-0179
ENSTGUG00000002858.1
H0YXC8
HNRNPD
3
LLPS-Tag-0931
ENSTGUG00000003138.1
H0YY68
HNRNPK
4
LLPS-Tag-1796
ENSTGUG00000017346.1
H1A408
KHDRBS1
5
LLPS-Tag-2135
ENSTGUG00000017303.1
H1A3W6
MAK16
6
LLPS-Tag-2123
ENSTGUG00000004452.1
H0Z219
YTHDC1