Ovis aries      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ova-1615
ENSOARG00000016240.1
W5Q400
HNRNPA1
2
LLPS-Ova-3731
ENSOARG00000000579.1
W5NR02
HNRNPD
3
LLPS-Ova-1880
ENSOARG00000005864.1
W5P779
HNRNPL
4
LLPS-Ova-0962
ENSOARG00000000666.1
W5NR95
KHDRBS1
5
LLPS-Ova-1582
ENSOARG00000005603.1
W5P6F5
KHDRBS2
6
LLPS-Ova-0439
ENSOARG00000005036.1
W5P4P5
KHDRBS3
7
LLPS-Ova-0242
ENSOARG00000008935.1
W5PGN1
LOC101123349
8
LLPS-Ova-1311
ENSOARG00000000384.1
W5NQE1
MAK16
9
LLPS-Ova-1144
ENSOARG00000019301.1
W5QDD6
NGDN
10
LLPS-Ova-0096
ENSOARG00000010884.1
W5PMJ5
RBMX
11
LLPS-Ova-0134
ENSOARG00000005425.1
W5P5W7
SMN2
12
LLPS-Ova-2343
ENSOARG00000018695.1
W5QBH6
TLE3
13
LLPS-Ova-0690
ENSOARG00000008633.1
W5PFP8
YTHDC1