Oryctolagus cuniculus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-2571
ENSOCUG00000017097.2
G1TD01
2
LLPS-Orc-0566
ENSOCUG00000001357.2
G1SF95
HNRNPD
3
LLPS-Orc-0570
ENSOCUG00000010364.2
O19049
HNRNPK
4
LLPS-Orc-1725
ENSOCUG00000002943.3
G1SIP2
HNRNPL
5
LLPS-Orc-2262
ENSOCUG00000007654.3
G1STI3
KHDRBS1
6
LLPS-Orc-0087
ENSOCUG00000012344.3
G1T339
KHDRBS2
7
LLPS-Orc-0379
ENSOCUG00000000743.3
G1SDZ1
KHDRBS3
8
LLPS-Orc-2882
ENSOCUG00000008735.3
G1SVS1
MAK16
9
LLPS-Orc-2099
ENSOCUG00000013973.2
G1T6H3
NGDN
10
LLPS-Orc-0332
ENSOCUG00000007220.2
G1U5N7
RBMX
11
LLPS-Orc-0168
ENSOCUG00000023043.2
G1TIB1
TLE3
12
LLPS-Orc-1010
ENSOCUG00000015886.3
G1TAG1
YTHDC1