Ictidomys tridecemlineatus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-0751
ENSSTOG00000006551.3
I3M849
Hnrnpa1
2
LLPS-Ict-0235
ENSSTOG00000014107.3
A0A287CYM1
HNRNPK
3
LLPS-Ict-1113
ENSSTOG00000005618.3
I3M6E5
HNRNPL
4
LLPS-Ict-0462
ENSSTOG00000014138.3
I3MMC5
KHDRBS1
5
LLPS-Ict-0498
ENSSTOG00000011529.3
I3MHI1
KHDRBS2
6
LLPS-Ict-1221
ENSSTOG00000008710.3
I3MC50
KHDRBS3
7
LLPS-Ict-1817
ENSSTOG00000012288.3
I3MIW3
LOC101965836
8
LLPS-Ict-2047
ENSSTOG00000007812.3
I3MAG8
MAK16
9
LLPS-Ict-1595
ENSSTOG00000002637.3
I3M0T5
NGDN
10
LLPS-Ict-1815
ENSSTOG00000006211.3
I3M7G6
RBMXL1
11
LLPS-Ict-4087
ENSSTOG00000000531.3
I3LWU5
TLE3
12
LLPS-Ict-0237
ENSSTOG00000013652.3
I3MLF0
YTHDC1